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The map label for this gene is aglA [H]

Identifier: 50843098

GI number: 50843098

Start: 1771379

End: 1773052

Strand: Direct

Name: aglA [H]

Synonym: PPA1630

Alternate gene names: 50843098

Gene position: 1771379-1773052 (Clockwise)

Preceding gene: 50843097

Following gene: 50843101

Centisome position: 69.19

GC content: 61.23

Gene sequence:

>1674_bases
ATGACCACCTCCCCTACGATCAACGACTGGTGGAAGTCCGCTGTCGTCTATCAGGTCTACCCACGCAGCTTCGCCGACTC
GAACGGAGACGGCATTGGCGACGTGCGTGGCATCATCGACCACCTCGACCACCTCGTCACCTTGGGTGTCGACGCCCTGT
GGATCTCACCGTGGTACCCCTCCCCCATGGCTGACGGCGGATACGACGTCAGCGACTACTGCGACATCAACCCGGACTTT
GGCACCCTCGCCGATGCGGACGCCCTCGTGGCACAGGCGCACGAGCTGGGTCTGCGGGTCATCATCGATCTCGTCCCGAA
CCACTCCTCTCAAGAGCATCCATGGTTCAAAAAGGCGTTAGCCGCAGCTCCCGGCTCCCCAGAACGCGACCGCTACATCT
TTCGTGATGGCCGGGGCGAGAACGGTGAACTTCCCCCGAACAACTGGCCGTCAGTTTTCGGCAGCGGCGCATGGGAGCGC
ATCACCGAGCCGGACGGCACTCCCGGTCAGTGGTACCTACACTTTTTTGACGTTTCCCAGCCCGACTGGAACTGGGAGAA
CTCCGACGTCCTCGAAGAGTTTGACCGGGTGCTGAGGTTCTGGTTCGACCGCGGGATCGACGGTTTCCGCATCGACGTCG
CCAACTCGCTGGTTAAGGAATCCGGTCTTCCAGATCTCCCCGAGAACGAAAAGTTCGGCGAGCTCGTCGGGGATAGTCCG
ATGTGGGATCAGCCTGAACTTGCATCAATTCAGCGACGCTGGCGTGCTATCGCCGACGAATACGCCGATACTCCCGAGGG
ACCCAGGATGTTTGTCGCCGAGGCTTACCTCCCCCACGACCGCCTGGTCCGCTACCTCGAGTCAGATCGGCTGCATACGT
CCTTTAACTTCGAGTTCCTCATCTCGGCGTGGAAGGCCAACTCGCTTCGCACCACGATCACCGAATCGCTAGCAGCTCAC
GAGTCGGTGGGCGCTAGTGCCACCTGGGTACTTGGTAACCACGACAATGTCCGCCCGGTCTCCCGCTACGGCAAGGAGAT
CTCCGGGCTGGACTTCTCGGATCCGTCGGCTCCGCACGCCCAGTTTCATGGCACCCCTACCGATGTGGCTCTGGGACGGT
GTCGGGCTCGCGCCGCCGCCATGCTGGAGCTGGCTCTACCGGGCGGTGCCTACATTTACCAAGGCGAAGAACTTGGCCTC
CCAGAGGTCGAAGATCTTCCCGAAGAAACCCTCCAAGACCCCACCTGGAAACGTTCTGGACACACAGATCGCGGTCGTGA
CGGATGTCGCGTTCCCATGCCGTGGAGCGGTTCCAACGCACCCTATGGGTGGTCGACAAACGCGAACACCTGGCTCCCCA
TGCCGAGTAATTGGGCCGAGTGGACCGTCGAATCTGAGCAGAACGATTCGTCATCCTTCTTTGCCCTCTACCGCACCCTA
CTGGCCGAGCGCCATGCCAACCCAGCACTGGGCGCCGGAACGATGACTTGGAACGAGTCCAGCGACGAGGTCCTCGACTT
TTCCCGCGAGCCCGGTTTCCGGTGCATCGTCAACTTCGGCGCCGAAAAGGTGACCGTGGACGCTGACGCGGTTATCGCAT
CGTCGATTCCGTTGGACACCCAAGGTAAGACGGTGTCAGTCGGACGCGATCAGGCTGTCTGGTTGCGAGTCTGA

Upstream 100 bases:

>100_bases
CGGTCGCGAAGTCCGCGCCAACTGAGTCTTCCCTCCACGAGAGTGGCCAGCCCTGGCCGTCGTGTCTGTTCCTACCCCAC
GCAACCCCATAAGGAGCCCC

Downstream 100 bases:

>100_bases
ACGTCGATCACACCGTGACGAGGTAGGCCGATAAGGCCTGCCTCGTCTGGTCGTCGATGGGCACCGAAGCGCCCGTCTTC
GGATCGACACAAACCAGCAC

Product: alpha-glucosidase/amylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTTSPTINDWWKSAVVYQVYPRSFADSNGDGIGDVRGIIDHLDHLVTLGVDALWISPWYPSPMADGGYDVSDYCDINPDF
GTLADADALVAQAHELGLRVIIDLVPNHSSQEHPWFKKALAAAPGSPERDRYIFRDGRGENGELPPNNWPSVFGSGAWER
ITEPDGTPGQWYLHFFDVSQPDWNWENSDVLEEFDRVLRFWFDRGIDGFRIDVANSLVKESGLPDLPENEKFGELVGDSP
MWDQPELASIQRRWRAIADEYADTPEGPRMFVAEAYLPHDRLVRYLESDRLHTSFNFEFLISAWKANSLRTTITESLAAH
ESVGASATWVLGNHDNVRPVSRYGKEISGLDFSDPSAPHAQFHGTPTDVALGRCRARAAAMLELALPGGAYIYQGEELGL
PEVEDLPEETLQDPTWKRSGHTDRGRDGCRVPMPWSGSNAPYGWSTNANTWLPMPSNWAEWTVESEQNDSSSFFALYRTL
LAERHANPALGAGTMTWNESSDEVLDFSREPGFRCIVNFGAEKVTVDADAVIASSIPLDTQGKTVSVGRDQAVWLRV

Sequences:

>Translated_557_residues
MTTSPTINDWWKSAVVYQVYPRSFADSNGDGIGDVRGIIDHLDHLVTLGVDALWISPWYPSPMADGGYDVSDYCDINPDF
GTLADADALVAQAHELGLRVIIDLVPNHSSQEHPWFKKALAAAPGSPERDRYIFRDGRGENGELPPNNWPSVFGSGAWER
ITEPDGTPGQWYLHFFDVSQPDWNWENSDVLEEFDRVLRFWFDRGIDGFRIDVANSLVKESGLPDLPENEKFGELVGDSP
MWDQPELASIQRRWRAIADEYADTPEGPRMFVAEAYLPHDRLVRYLESDRLHTSFNFEFLISAWKANSLRTTITESLAAH
ESVGASATWVLGNHDNVRPVSRYGKEISGLDFSDPSAPHAQFHGTPTDVALGRCRARAAAMLELALPGGAYIYQGEELGL
PEVEDLPEETLQDPTWKRSGHTDRGRDGCRVPMPWSGSNAPYGWSTNANTWLPMPSNWAEWTVESEQNDSSSFFALYRTL
LAERHANPALGAGTMTWNESSDEVLDFSREPGFRCIVNFGAEKVTVDADAVIASSIPLDTQGKTVSVGRDQAVWLRV
>Mature_556_residues
TTSPTINDWWKSAVVYQVYPRSFADSNGDGIGDVRGIIDHLDHLVTLGVDALWISPWYPSPMADGGYDVSDYCDINPDFG
TLADADALVAQAHELGLRVIIDLVPNHSSQEHPWFKKALAAAPGSPERDRYIFRDGRGENGELPPNNWPSVFGSGAWERI
TEPDGTPGQWYLHFFDVSQPDWNWENSDVLEEFDRVLRFWFDRGIDGFRIDVANSLVKESGLPDLPENEKFGELVGDSPM
WDQPELASIQRRWRAIADEYADTPEGPRMFVAEAYLPHDRLVRYLESDRLHTSFNFEFLISAWKANSLRTTITESLAAHE
SVGASATWVLGNHDNVRPVSRYGKEISGLDFSDPSAPHAQFHGTPTDVALGRCRARAAAMLELALPGGAYIYQGEELGLP
EVEDLPEETLQDPTWKRSGHTDRGRDGCRVPMPWSGSNAPYGWSTNANTWLPMPSNWAEWTVESEQNDSSSFFALYRTLL
AERHANPALGAGTMTWNESSDEVLDFSREPGFRCIVNFGAEKVTVDADAVIASSIPLDTQGKTVSVGRDQAVWLRV

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=538, Percent_Identity=31.9702602230483, Blast_Score=244, Evalue=2e-64,
Organism=Escherichia coli, GI1790687, Length=520, Percent_Identity=36.3461538461538, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1786604, Length=252, Percent_Identity=26.1904761904762, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32565753, Length=554, Percent_Identity=23.6462093862816, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25147709, Length=411, Percent_Identity=26.0340632603406, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=516, Percent_Identity=31.7829457364341, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6319776, Length=563, Percent_Identity=31.0834813499112, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321731, Length=563, Percent_Identity=30.9058614564831, Blast_Score=241, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6321726, Length=522, Percent_Identity=30.0766283524904, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6322241, Length=524, Percent_Identity=30.3435114503817, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6322021, Length=524, Percent_Identity=30.3435114503817, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6324416, Length=524, Percent_Identity=30.3435114503817, Blast_Score=227, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24583747, Length=533, Percent_Identity=37.8986866791745, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24583749, Length=533, Percent_Identity=37.8986866791745, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24583745, Length=523, Percent_Identity=36.7112810707457, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24586599, Length=555, Percent_Identity=33.3333333333333, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24586597, Length=552, Percent_Identity=34.963768115942, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI221330053, Length=551, Percent_Identity=35.2087114337568, Blast_Score=292, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24586593, Length=522, Percent_Identity=35.2490421455939, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI45549022, Length=568, Percent_Identity=32.5704225352113, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24586591, Length=524, Percent_Identity=35.3053435114504, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24586589, Length=569, Percent_Identity=34.0949033391916, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24586587, Length=575, Percent_Identity=31.4782608695652, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI281360393, Length=469, Percent_Identity=32.8358208955224, Blast_Score=203, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 62136; Mature: 62005

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSPTINDWWKSAVVYQVYPRSFADSNGDGIGDVRGIIDHLDHLVTLGVDALWISPWYP
CCCCCCHHHHHHCCEEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCC
SPMADGGYDVSDYCDINPDFGTLADADALVAQAHELGLRVIIDLVPNHSSQEHPWFKKAL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHH
AAAPGSPERDRYIFRDGRGENGELPPNNWPSVFGSGAWERITEPDGTPGQWYLHFFDVSQ
HCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCEEEEEEEECCC
PDWNWENSDVLEEFDRVLRFWFDRGIDGFRIDVANSLVKESGLPDLPENEKFGELVGDSP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
MWDQPELASIQRRWRAIADEYADTPEGPRMFVAEAYLPHDRLVRYLESDRLHTSFNFEFL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHHHHHCCCEEECCCEEE
ISAWKANSLRTTITESLAAHESVGASATWVLGNHDNVRPVSRYGKEISGLDFSDPSAPHA
EEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCHHCCCCCCCCCCCCC
QFHGTPTDVALGRCRARAAAMLELALPGGAYIYQGEELGLPEVEDLPEETLQDPTWKRSG
EECCCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCHHHCCHHHHCCCCCCCCC
HTDRGRDGCRVPMPWSGSNAPYGWSTNANTWLPMPSNWAEWTVESEQNDSSSFFALYRTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHCEEECCCCCCCHHHHHHHHHH
LAERHANPALGAGTMTWNESSDEVLDFSREPGFRCIVNFGAEKVTVDADAVIASSIPLDT
HHHHCCCCCCCCCEEECCCCCHHHHHCCCCCCCEEEEECCCCEEEECCCHHEECCCCCCC
QGKTVSVGRDQAVWLRV
CCCEEECCCCCEEEEEC
>Mature Secondary Structure 
TTSPTINDWWKSAVVYQVYPRSFADSNGDGIGDVRGIIDHLDHLVTLGVDALWISPWYP
CCCCCHHHHHHCCEEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCC
SPMADGGYDVSDYCDINPDFGTLADADALVAQAHELGLRVIIDLVPNHSSQEHPWFKKAL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHH
AAAPGSPERDRYIFRDGRGENGELPPNNWPSVFGSGAWERITEPDGTPGQWYLHFFDVSQ
HCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCEEEEEEEECCC
PDWNWENSDVLEEFDRVLRFWFDRGIDGFRIDVANSLVKESGLPDLPENEKFGELVGDSP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCCCCCHHHHCCCCC
MWDQPELASIQRRWRAIADEYADTPEGPRMFVAEAYLPHDRLVRYLESDRLHTSFNFEFL
CCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCHHHHHHHHHHCCCEEECCCEEE
ISAWKANSLRTTITESLAAHESVGASATWVLGNHDNVRPVSRYGKEISGLDFSDPSAPHA
EEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCHHCCCCCCCCCCCCC
QFHGTPTDVALGRCRARAAAMLELALPGGAYIYQGEELGLPEVEDLPEETLQDPTWKRSG
EECCCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCHHHCCHHHHCCCCCCCCC
HTDRGRDGCRVPMPWSGSNAPYGWSTNANTWLPMPSNWAEWTVESEQNDSSSFFALYRTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHCEEECCCCCCCHHHHHHHHHH
LAERHANPALGAGTMTWNESSDEVLDFSREPGFRCIVNFGAEKVTVDADAVIASSIPLDT
HHHHCCCCCCCCCEEECCCCCHHHHHCCCCCCCEEEEECCCCEEEECCCHHEECCCCCCC
QGKTVSVGRDQAVWLRV
CCCEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]