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The map label for this gene is yaeL [C]

Identifier: 50842987

GI number: 50842987

Start: 1631256

End: 1632536

Strand: Reverse

Name: yaeL [C]

Synonym: PPA1509

Alternate gene names: 50842987

Gene position: 1632536-1631256 (Counterclockwise)

Preceding gene: 50842988

Following gene: 50842986

Centisome position: 63.76

GC content: 59.25

Gene sequence:

>1281_bases
GTGATAGTTGTAGTCGAAGTGCTGGCTGGAATCGTCTTCTTCGGCCTCATCATCCTCTCGGTGCTACTTCATGAGTGCGG
TCACTTCATCCCGGCGAAGATCTTCGGGGTCAAGGTCACCGAGTTCTTTGCCGGGTTCGGACCGAAGATCTGGTCGTTCA
CGCCCGGTGAGACGGAGTACGGGTTCAAATGGATCCCGCTGGGTGGCTATGTGCGCCTCATCGGGATGTACCCCGCCAAG
GTCCACCATCGTCACAGCAATCGGCTTACCAGATTTGCTGATGAGGCGCGTGTTGCTGAGGTCGAGGGCATCACAGACGC
CGATCAAGGTCGGCTTTTCAGTGACAAGCCGGTGTGGCAGCGCCTCATCATCATGAGCGGTGGTATTCTTACCAATCTGC
TGCTGGCCTTCCTGCTGTTCTGGGCGGTTTTCGGCATTCACGGACGAGCCGACCAGACGACGACAGTCGCTGCAGTCACC
CCCTGCGCCCATTCCGCCCAGACCAGCGGCCCATGCTCCAAGGAAGACCGTCGTGCACCGGCTGCCGAGGCCGGTGTGCG
AGCGGGGGATCGCATCGTCTCTTTTAACGGTCGACAGGTGGATTCCTGGTCGCAACTTCAGGAGTTCATCCGTGGTAATG
GTGGCGGCGAAGTGCGTCTCGGAGTGGAACGCGATGGCGCTTTCGTCAGCCTTACGCCCACGCACACCCTCCTCACCAAG
GTGCCTGACCTCAGCACTCCCGGTCGTACAGTCGAGGCGGGTTACTTGGGCGTGAGCCCGACGATGGTCATTGTTCATTC
TGGGCCGGGCGATACCGTCTCCCAGATGTGGACGATGTCGAAACAGTCGTTGAGCGCATTGGCCAGACTTCCAGTTCTGA
CGTGGAACGTCGCCTCCGATCTGGTGACCGGTCAGGCTCGCGACGCCAACAGCCCAATGAGCATCGTTGGAGCCTCTCGG
GTGGCCGGGGATGTTGCCGGCGATTCCCAGCTGACCTTGGGCGACAAGATCGCCACCGGTGCAAGCTTGCTGGGTGGCCT
CAATCTCTTTTTGTTTTGGTTCAACGTCGTGCCATTGCCGCCCATGGACGGTGGACATATCGCTGGAGCCATCTATGAGG
CAGGTAAGCGGGGGCTATTTAAACTTGCCAGAAAGCCTGATCCTGGCCCGGCGGACACCGCGATGATGCTGCCGGTGGCA
TGGACAATCGGGGCGCTTATGCTCATGATGGGACTCGTCCTCGTTGTCGCAGATGTCGTATCGCCGGTAAAAATTTTCTA
A

Upstream 100 bases:

>100_bases
GACATGTCGGTGACGAGGCCCTCACCCTCGATGCCGTGTTGGCCGCCGACGCCTGGGGTCGTCGTCGCGCCGCCGAGGTG
TGTGCCCGGGGGATTCGCCG

Downstream 100 bases:

>100_bases
TTATGGCTTCGTATCGGTGAATGAGCTGTAAATTATCGCTCGCAGTGCGGGAATGTTTGGTGAATTGTCAATGATGAGCA
TTCCTGTCCTCGTGCCGACC

Product: membrane-spanning metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MIVVVEVLAGIVFFGLIILSVLLHECGHFIPAKIFGVKVTEFFAGFGPKIWSFTPGETEYGFKWIPLGGYVRLIGMYPAK
VHHRHSNRLTRFADEARVAEVEGITDADQGRLFSDKPVWQRLIIMSGGILTNLLLAFLLFWAVFGIHGRADQTTTVAAVT
PCAHSAQTSGPCSKEDRRAPAAEAGVRAGDRIVSFNGRQVDSWSQLQEFIRGNGGGEVRLGVERDGAFVSLTPTHTLLTK
VPDLSTPGRTVEAGYLGVSPTMVIVHSGPGDTVSQMWTMSKQSLSALARLPVLTWNVASDLVTGQARDANSPMSIVGASR
VAGDVAGDSQLTLGDKIATGASLLGGLNLFLFWFNVVPLPPMDGGHIAGAIYEAGKRGLFKLARKPDPGPADTAMMLPVA
WTIGALMLMMGLVLVVADVVSPVKIF

Sequences:

>Translated_426_residues
MIVVVEVLAGIVFFGLIILSVLLHECGHFIPAKIFGVKVTEFFAGFGPKIWSFTPGETEYGFKWIPLGGYVRLIGMYPAK
VHHRHSNRLTRFADEARVAEVEGITDADQGRLFSDKPVWQRLIIMSGGILTNLLLAFLLFWAVFGIHGRADQTTTVAAVT
PCAHSAQTSGPCSKEDRRAPAAEAGVRAGDRIVSFNGRQVDSWSQLQEFIRGNGGGEVRLGVERDGAFVSLTPTHTLLTK
VPDLSTPGRTVEAGYLGVSPTMVIVHSGPGDTVSQMWTMSKQSLSALARLPVLTWNVASDLVTGQARDANSPMSIVGASR
VAGDVAGDSQLTLGDKIATGASLLGGLNLFLFWFNVVPLPPMDGGHIAGAIYEAGKRGLFKLARKPDPGPADTAMMLPVA
WTIGALMLMMGLVLVVADVVSPVKIF
>Mature_426_residues
MIVVVEVLAGIVFFGLIILSVLLHECGHFIPAKIFGVKVTEFFAGFGPKIWSFTPGETEYGFKWIPLGGYVRLIGMYPAK
VHHRHSNRLTRFADEARVAEVEGITDADQGRLFSDKPVWQRLIIMSGGILTNLLLAFLLFWAVFGIHGRADQTTTVAAVT
PCAHSAQTSGPCSKEDRRAPAAEAGVRAGDRIVSFNGRQVDSWSQLQEFIRGNGGGEVRLGVERDGAFVSLTPTHTLLTK
VPDLSTPGRTVEAGYLGVSPTMVIVHSGPGDTVSQMWTMSKQSLSALARLPVLTWNVASDLVTGQARDANSPMSIVGASR
VAGDVAGDSQLTLGDKIATGASLLGGLNLFLFWFNVVPLPPMDGGHIAGAIYEAGKRGLFKLARKPDPGPADTAMMLPVA
WTIGALMLMMGLVLVVADVVSPVKIF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=199, Percent_Identity=28.1407035175879, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 45533; Mature: 45533

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50817 INTEIN_N_TER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVVEVLAGIVFFGLIILSVLLHECGHFIPAKIFGVKVTEFFAGFGPKIWSFTPGETEY
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEHHHHHHCCCCCCCCCCCCCCCC
GFKWIPLGGYVRLIGMYPAKVHHRHSNRLTRFADEARVAEVEGITDADQGRLFSDKPVWQ
CEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
RLIIMSGGILTNLLLAFLLFWAVFGIHGRADQTTTVAAVTPCAHSAQTSGPCSKEDRRAP
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCCC
AAEAGVRAGDRIVSFNGRQVDSWSQLQEFIRGNGGGEVRLGVERDGAFVSLTPTHTLLTK
CHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHC
VPDLSTPGRTVEAGYLGVSPTMVIVHSGPGDTVSQMWTMSKQSLSALARLPVLTWNVASD
CCCCCCCCCEEECCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEHHHH
LVTGQARDANSPMSIVGASRVAGDVAGDSQLTLGDKIATGASLLGGLNLFLFWFNVVPLP
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
PMDGGHIAGAIYEAGKRGLFKLARKPDPGPADTAMMLPVAWTIGALMLMMGLVLVVADVV
CCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
SPVKIF
CCHHCC
>Mature Secondary Structure
MIVVVEVLAGIVFFGLIILSVLLHECGHFIPAKIFGVKVTEFFAGFGPKIWSFTPGETEY
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEHHHHHHCCCCCCCCCCCCCCCC
GFKWIPLGGYVRLIGMYPAKVHHRHSNRLTRFADEARVAEVEGITDADQGRLFSDKPVWQ
CEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
RLIIMSGGILTNLLLAFLLFWAVFGIHGRADQTTTVAAVTPCAHSAQTSGPCSKEDRRAP
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCCC
AAEAGVRAGDRIVSFNGRQVDSWSQLQEFIRGNGGGEVRLGVERDGAFVSLTPTHTLLTK
CHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEECCHHHHHHC
VPDLSTPGRTVEAGYLGVSPTMVIVHSGPGDTVSQMWTMSKQSLSALARLPVLTWNVASD
CCCCCCCCCEEECCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEHHHH
LVTGQARDANSPMSIVGASRVAGDVAGDSQLTLGDKIATGASLLGGLNLFLFWFNVVPLP
HHCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
PMDGGHIAGAIYEAGKRGLFKLARKPDPGPADTAMMLPVAWTIGALMLMMGLVLVVADVV
CCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
SPVKIF
CCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]