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The map label for this gene is coaD

Identifier: 50842942

GI number: 50842942

Start: 1579669

End: 1580142

Strand: Reverse

Name: coaD

Synonym: PPA1463

Alternate gene names: 50842942

Gene position: 1580142-1579669 (Counterclockwise)

Preceding gene: 50842943

Following gene: 50842941

Centisome position: 61.72

GC content: 55.49

Gene sequence:

>474_bases
GTGAAAGCAGTCTTTTCAGGGTCATTCGACCCCATCACCCTCGGTCACGTTGACATCGTGACCCGAGCAGCCGAACTCAT
CGACGAGGTCGTCGTCGGAGTGGCCGTGAACTCCGCGAAGAACGGCATCTTCTCCATGGATGAGCGGGTGGCCTTCGTTA
AGGATGCTGTCGCTGATATTCCCGGTGTCGAGGTGGCGCTCGTTGACGGACTGCTGGTCGACTTCTGCACCGAAATGGGA
GCTGACGCAATCATCCGCGGGTTGCGATTTGGTGGCGACTTCGACTACGAACTCCAGATGGCTCACCTCAATAAGGCCAT
GAGCGGTATTGAAACCATTTTGCTCCCGGCTGGCCGTGAATTCGGCACGATCAGCTCCTCGATGATTCGCTCTGCTGCTT
GTAATGGCGGCAATGTATCCGAGTTTGTGCCGGGAATGGTTAATACCGCGTTGCATGAAAGATTCCCGCATTAA

Upstream 100 bases:

>100_bases
CGGATGGATACGAGTCGTGGAATTCTCGCTACGGCGAGACAGTTGTCTATTACGCCCAACGTACCGGTGAGCCGGAGGCA
GATGCGGGCAGGGAGCAGCA

Downstream 100 bases:

>100_bases
TGATTTCTTCAGATATTGGAGAACTCTGCTCGCACCATTCCTCTTTGGGAGTTATGATTTTCGGAAAGCGTTGGCGACAT
CGGTTGCCGATCCCTTGGGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKAVFSGSFDPITLGHVDIVTRAAELIDEVVVGVAVNSAKNGIFSMDERVAFVKDAVADIPGVEVALVDGLLVDFCTEMG
ADAIIRGLRFGGDFDYELQMAHLNKAMSGIETILLPAGREFGTISSSMIRSAACNGGNVSEFVPGMVNTALHERFPH

Sequences:

>Translated_157_residues
MKAVFSGSFDPITLGHVDIVTRAAELIDEVVVGVAVNSAKNGIFSMDERVAFVKDAVADIPGVEVALVDGLLVDFCTEMG
ADAIIRGLRFGGDFDYELQMAHLNKAMSGIETILLPAGREFGTISSSMIRSAACNGGNVSEFVPGMVNTALHERFPH
>Mature_157_residues
MKAVFSGSFDPITLGHVDIVTRAAELIDEVVVGVAVNSAKNGIFSMDERVAFVKDAVADIPGVEVALVDGLLVDFCTEMG
ADAIIRGLRFGGDFDYELQMAHLNKAMSGIETILLPAGREFGTISSSMIRSAACNGGNVSEFVPGMVNTALHERFPH

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=40.3973509933775, Blast_Score=135, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PROAC (Q6A7Q4)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056169.1
- ProteinModelPortal:   Q6A7Q4
- SMR:   Q6A7Q4
- GeneID:   2933115
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1463
- NMPDR:   fig|267747.1.peg.1446
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   CLSK2523203
- BioCyc:   PACN267747:PPA1463-MONOMER
- BRENDA:   2.7.7.3
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 16660; Mature: 16660

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVFSGSFDPITLGHVDIVTRAAELIDEVVVGVAVNSAKNGIFSMDERVAFVKDAVADI
CCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
PGVEVALVDGLLVDFCTEMGADAIIRGLRFGGDFDYELQMAHLNKAMSGIETILLPAGRE
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
FGTISSSMIRSAACNGGNVSEFVPGMVNTALHERFPH
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAVFSGSFDPITLGHVDIVTRAAELIDEVVVGVAVNSAKNGIFSMDERVAFVKDAVADI
CCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
PGVEVALVDGLLVDFCTEMGADAIIRGLRFGGDFDYELQMAHLNKAMSGIETILLPAGRE
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
FGTISSSMIRSAACNGGNVSEFVPGMVNTALHERFPH
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA