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The map label for this gene is sdhB [H]

Identifier: 50842916

GI number: 50842916

Start: 1553582

End: 1554355

Strand: Reverse

Name: sdhB [H]

Synonym: PPA1437

Alternate gene names: 50842916

Gene position: 1554355-1553582 (Counterclockwise)

Preceding gene: 50842917

Following gene: 50842915

Centisome position: 60.71

GC content: 60.72

Gene sequence:

>774_bases
GTGAAGATCAACCTGCGAATCTGGCGTCAGCGCAATTCCAAGGATCAGGGCCGCCTCGTCGAGTACACCCTGGACGGTGT
TTCCGGTGATATGTCCTTCCTTGAGATGTTGGACATGCTCAACGAGAACCTCACCGCTCAGGGTGAAGAGCCCGTCGCAT
TTGACTCGGACTGCCGCGAGGGTATTTGCGGTCAGTGCGGCGTCGTCATCAATGGTGTGCCGCACGGTGGTATGGGTGCT
GCCCAGCCGGTGCGTACCACTACGTGTCAGCTGCACATGCGCTCCTTCGCCGATGGCTCGACCATCACGATCGAGCCATG
GAAGTCGGGTGCCTTCCCGATTCTGCGTGACCTTATCGTGGATCGCTCGGCCCTTGACCGTGTCATCCAGGCTGGCGGCT
ATGTCTCGGTGAACACCGGTGCTGCCCCGGACGCTCACGCTGTTCAGGTCAACAAGAAGCGCTCTGACCGCTCCTTCGAC
GCCGCTACCTGCATCGGTTGTGGCGCCTGCGTGGCGGCCTGCCCGAACGGCTCCTCGATGCTGTTTACTTCTGCGAAGAT
CACTCACCTGGCCATGCTTCCGCAGGGTCAGCCGGAGCGGATGCGTCGTGTTAAGGCTATGGCTGCGCAGAACGACGCTG
AAGGATTCGGTGGCTGCACCAACATTGGTGAGTGCGCCTCGGTGTGCCCGAAAGGTATTCCGCTGGAGTCCATCAGCCAG
CTCAACCGCGACCTCATTGCGTCGCTGTTCAAGCACGACGGCAAGGACGACTGA

Upstream 100 bases:

>100_bases
ACGTCGCTGCCTGGGAGTGGACTGGCGAAGGCCACAAGCCGACCCTGCACAAGGAGCCGCTGGTCTACAAGTCCATCCAG
GTCAAGCAGAGGAGCTACAA

Downstream 100 bases:

>100_bases
GTCCTGACTCGTGTGGTCGATTACTCGGGCTCCGACACCTCGCGGTGTCGGAGCCCGGTTATGTTGTGGAGCACTGCCTG
TTGGCGGGCACGAGTGATGG

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKINLRIWRQRNSKDQGRLVEYTLDGVSGDMSFLEMLDMLNENLTAQGEEPVAFDSDCREGICGQCGVVINGVPHGGMGA
AQPVRTTTCQLHMRSFADGSTITIEPWKSGAFPILRDLIVDRSALDRVIQAGGYVSVNTGAAPDAHAVQVNKKRSDRSFD
AATCIGCGACVAACPNGSSMLFTSAKITHLAMLPQGQPERMRRVKAMAAQNDAEGFGGCTNIGECASVCPKGIPLESISQ
LNRDLIASLFKHDGKDD

Sequences:

>Translated_257_residues
MKINLRIWRQRNSKDQGRLVEYTLDGVSGDMSFLEMLDMLNENLTAQGEEPVAFDSDCREGICGQCGVVINGVPHGGMGA
AQPVRTTTCQLHMRSFADGSTITIEPWKSGAFPILRDLIVDRSALDRVIQAGGYVSVNTGAAPDAHAVQVNKKRSDRSFD
AATCIGCGACVAACPNGSSMLFTSAKITHLAMLPQGQPERMRRVKAMAAQNDAEGFGGCTNIGECASVCPKGIPLESISQ
LNRDLIASLFKHDGKDD
>Mature_257_residues
MKINLRIWRQRNSKDQGRLVEYTLDGVSGDMSFLEMLDMLNENLTAQGEEPVAFDSDCREGICGQCGVVINGVPHGGMGA
AQPVRTTTCQLHMRSFADGSTITIEPWKSGAFPILRDLIVDRSALDRVIQAGGYVSVNTGAAPDAHAVQVNKKRSDRSFD
AATCIGCGACVAACPNGSSMLFTSAKITHLAMLPQGQPERMRRVKAMAAQNDAEGFGGCTNIGECASVCPKGIPLESISQ
LNRDLIASLFKHDGKDD

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790596, Length=212, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786943, Length=258, Percent_Identity=25.1937984496124, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27522; Mature: 27522

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINLRIWRQRNSKDQGRLVEYTLDGVSGDMSFLEMLDMLNENLTAQGEEPVAFDSDCRE
CEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHC
GICGQCGVVINGVPHGGMGAAQPVRTTTCQLHMRSFADGSTITIEPWKSGAFPILRDLIV
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DRSALDRVIQAGGYVSVNTGAAPDAHAVQVNKKRSDRSFDAATCIGCGACVAACPNGSSM
CHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEE
LFTSAKITHLAMLPQGQPERMRRVKAMAAQNDAEGFGGCTNIGECASVCPKGIPLESISQ
EEEHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
LNRDLIASLFKHDGKDD
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKINLRIWRQRNSKDQGRLVEYTLDGVSGDMSFLEMLDMLNENLTAQGEEPVAFDSDCRE
CEEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHC
GICGQCGVVINGVPHGGMGAAQPVRTTTCQLHMRSFADGSTITIEPWKSGAFPILRDLIV
CCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DRSALDRVIQAGGYVSVNTGAAPDAHAVQVNKKRSDRSFDAATCIGCGACVAACPNGSSM
CHHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEE
LFTSAKITHLAMLPQGQPERMRRVKAMAAQNDAEGFGGCTNIGECASVCPKGIPLESISQ
EEEHHHEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
LNRDLIASLFKHDGKDD
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]