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The map label for this gene is rnhB

Identifier: 50842913

GI number: 50842913

Start: 1551333

End: 1551947

Strand: Reverse

Name: rnhB

Synonym: PPA1433

Alternate gene names: 50842913

Gene position: 1551947-1551333 (Counterclockwise)

Preceding gene: 50842914

Following gene: 50842912

Centisome position: 60.62

GC content: 59.84

Gene sequence:

>615_bases
ATGGGCCATGAACGGGCCCTAGCGAGGGCCGGACTCGGCCCCGTGGCCGGATGCGACGAGGCGGGGCGGGGCGCGTGTGC
AGGGCCATTGGTAGCCGCAGCTGTCATTCTTGATGATCGCAGATCCGGCAGGATTGCGGGGCTAGCAGATTCCAAGACAC
TATCTGCGGCCAAGAGAGAGGCCCTGTTTAACGTCATCATGGATAAAGCTTTGGCAGTGTCGTGGGTACGTGTAGAAGCC
GACGAATGCGATCGGTTGGGGATGCAGGAGGCAGATATCAGCGGCTTAAGGCGTGCCGTGGTGAGGCTGGGAGTTGAACC
GGGATACGTGCTGTCGGACGGTTTCCCGGTCGACGGACTCACGGTTCCCGATCTGGGAATGTGGAAGGGCGATTCAGTGT
GTGCGTGTGTGGCAGCTGCCTCCATCGTGGCCAAAGTGGCCAGGGATCGCATCATGATCGCTATGGACGCCGAGATTCCT
GGTTACGATTTTGCGGTGCACAAGGGGTACGCGACAGCCTTACACCAGCGCCGTCTGAAGGAGTTAGGACCGTCTCGTCA
ACACCGGATGAGCTACGCCAATGTGCGACGAGCGGCTAGGCTTCATTCATCATGA

Upstream 100 bases:

>100_bases
ATAGGTCGTCGTCAGCTCCAGGCAAGGCGCGCATCTGCGTCGGTAACGCGTGCTGCCCTAAGTGACGGATTCCATGTCGG
TGCGAGTCGGGTCGGGGCCG

Downstream 100 bases:

>100_bases
GTGCCGAAGATCTGGAACAGTACGAGAATCGGATGGAGTTGGAGCTCTACCGCGAGTACAAGGACGTCGTCGGGATCTTC
AAATATGCCGTAGAAACCGA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MGHERALARAGLGPVAGCDEAGRGACAGPLVAAAVILDDRRSGRIAGLADSKTLSAAKREALFNVIMDKALAVSWVRVEA
DECDRLGMQEADISGLRRAVVRLGVEPGYVLSDGFPVDGLTVPDLGMWKGDSVCACVAAASIVAKVARDRIMIAMDAEIP
GYDFAVHKGYATALHQRRLKELGPSRQHRMSYANVRRAARLHSS

Sequences:

>Translated_204_residues
MGHERALARAGLGPVAGCDEAGRGACAGPLVAAAVILDDRRSGRIAGLADSKTLSAAKREALFNVIMDKALAVSWVRVEA
DECDRLGMQEADISGLRRAVVRLGVEPGYVLSDGFPVDGLTVPDLGMWKGDSVCACVAAASIVAKVARDRIMIAMDAEIP
GYDFAVHKGYATALHQRRLKELGPSRQHRMSYANVRRAARLHSS
>Mature_203_residues
GHERALARAGLGPVAGCDEAGRGACAGPLVAAAVILDDRRSGRIAGLADSKTLSAAKREALFNVIMDKALAVSWVRVEAD
ECDRLGMQEADISGLRRAVVRLGVEPGYVLSDGFPVDGLTVPDLGMWKGDSVCACVAAASIVAKVARDRIMIAMDAEIPG
YDFAVHKGYATALHQRRLKELGPSRQHRMSYANVRRAARLHSS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=189, Percent_Identity=47.6190476190476, Blast_Score=150, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PROAC (Q6A7T3)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056140.1
- ProteinModelPortal:   Q6A7T3
- SMR:   Q6A7T3
- GeneID:   2931526
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1433
- NMPDR:   fig|267747.1.peg.1417
- HOGENOM:   HBG584843
- OMA:   LFEEICA
- ProtClustDB:   PRK00015
- BioCyc:   PACN267747:PPA1433-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21694; Mature: 21563

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHERALARAGLGPVAGCDEAGRGACAGPLVAAAVILDDRRSGRIAGLADSKTLSAAKRE
CCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHH
ALFNVIMDKALAVSWVRVEADECDRLGMQEADISGLRRAVVRLGVEPGYVLSDGFPVDGL
HHHHHHHHHHHHHHHEEECHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
TVPDLGMWKGDSVCACVAAASIVAKVARDRIMIAMDAEIPGYDFAVHKGYATALHQRRLK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHH
ELGPSRQHRMSYANVRRAARLHSS
HHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GHERALARAGLGPVAGCDEAGRGACAGPLVAAAVILDDRRSGRIAGLADSKTLSAAKRE
CCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHH
ALFNVIMDKALAVSWVRVEADECDRLGMQEADISGLRRAVVRLGVEPGYVLSDGFPVDGL
HHHHHHHHHHHHHHHEEECHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCC
TVPDLGMWKGDSVCACVAAASIVAKVARDRIMIAMDAEIPGYDFAVHKGYATALHQRRLK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHH
ELGPSRQHRMSYANVRRAARLHSS
HHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA