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The map label for this gene is lepB [H]

Identifier: 50842914

GI number: 50842914

Start: 1551983

End: 1552807

Strand: Reverse

Name: lepB [H]

Synonym: PPA1434

Alternate gene names: 50842914

Gene position: 1552807-1551983 (Counterclockwise)

Preceding gene: 50842915

Following gene: 50842913

Centisome position: 60.65

GC content: 58.91

Gene sequence:

>825_bases
GTGGCGGATGACTACCGGGCGAGGCGGGCTGCAAACGGCGACACCAGGGACTCTGACGATGCAACAGCACGTGGGGAACA
GGCGTCTGGGTGGCAGCGCTTTCGGTCGGGGGCGATCGAAGTTGTTCTCATCGTCGTTGGTGCCCTCATCATCTCAGCTG
TGCTGCGTGGTTTCGTCGCTCAGATGTTTGTCATCCCGTCGAAGTCTATGCAAAACACCTTGCAGGTGGGCGACCGCGTG
ATCGCGGTGAAAGCCGCCGATTTTCATCGGGGCGACGTCGTCGTGTTCAAAGACACCGAACATTGGCTACCTGCTGCCCA
GGATCGCCGCTCTGTTCCAGGACAGATCCTCGAATTCGTCGGGTTGTTGCCTAACAAGAGCTCGAACTACCTCATTAAGC
GAGTGATCGGCATGCCTGGGGACACCGTTGCCTGCTGCAACGTCAACGGCCAGGTGACCGTCAACGGTAAGGCGCTTGAC
GAGCGGTCATACCTGTACTCCGAAAATGGTGAAATGGTTAAACCCTCGGCGATGGAATTCCGGGTCACTGTTCCTCGGGG
GCGGATGTTCGTCTTGGGGGACCATCGCAATGCCTCGGGTGACTCGCGCTATCACCTCCAAGACCTTGATCCGGGTGAGT
ATACGGGCGCTCCTGCGTTTGTGCCGCTCGATGACGTCGTTGGGCCGGCAAAGGCCATTCTCATGCCTCTCAATCGCATT
GAGGGACTGGGGACTCCTGACATTTTCCGAGGAATCCCGGATAGGTCGTCGTCAGCTCCAGGCAAGGCGCGCATCTGCGT
CGGTAACGCGTGCTGCCCTAAGTGA

Upstream 100 bases:

>100_bases
GGTAGGCGCGTCATGATGCAGCTTTTTTCTGTGCGTTGGTTACACTGCAAGGTGGCACCCGACGGGAAGTTCCCACAGGG
GATGAGGGAGAGGTTTTGCC

Downstream 100 bases:

>100_bases
CGGATTCCATGTCGGTGCGAGTCGGGTCGGGGCCGATGGGCCATGAACGGGCCCTAGCGAGGGCCGGACTCGGCCCCGTG
GCCGGATGCGACGAGGCGGG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MADDYRARRAANGDTRDSDDATARGEQASGWQRFRSGAIEVVLIVVGALIISAVLRGFVAQMFVIPSKSMQNTLQVGDRV
IAVKAADFHRGDVVVFKDTEHWLPAAQDRRSVPGQILEFVGLLPNKSSNYLIKRVIGMPGDTVACCNVNGQVTVNGKALD
ERSYLYSENGEMVKPSAMEFRVTVPRGRMFVLGDHRNASGDSRYHLQDLDPGEYTGAPAFVPLDDVVGPAKAILMPLNRI
EGLGTPDIFRGIPDRSSSAPGKARICVGNACCPK

Sequences:

>Translated_274_residues
MADDYRARRAANGDTRDSDDATARGEQASGWQRFRSGAIEVVLIVVGALIISAVLRGFVAQMFVIPSKSMQNTLQVGDRV
IAVKAADFHRGDVVVFKDTEHWLPAAQDRRSVPGQILEFVGLLPNKSSNYLIKRVIGMPGDTVACCNVNGQVTVNGKALD
ERSYLYSENGEMVKPSAMEFRVTVPRGRMFVLGDHRNASGDSRYHLQDLDPGEYTGAPAFVPLDDVVGPAKAILMPLNRI
EGLGTPDIFRGIPDRSSSAPGKARICVGNACCPK
>Mature_273_residues
ADDYRARRAANGDTRDSDDATARGEQASGWQRFRSGAIEVVLIVVGALIISAVLRGFVAQMFVIPSKSMQNTLQVGDRVI
AVKAADFHRGDVVVFKDTEHWLPAAQDRRSVPGQILEFVGLLPNKSSNYLIKRVIGMPGDTVACCNVNGQVTVNGKALDE
RSYLYSENGEMVKPSAMEFRVTVPRGRMFVLGDHRNASGDSRYHLQDLDPGEYTGAPAFVPLDDVVGPAKAILMPLNRIE
GLGTPDIFRGIPDRSSSAPGKARICVGNACCPK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29689; Mature: 29558

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDYRARRAANGDTRDSDDATARGEQASGWQRFRSGAIEVVLIVVGALIISAVLRGFVA
CCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QMFVIPSKSMQNTLQVGDRVIAVKAADFHRGDVVVFKDTEHWLPAAQDRRSVPGQILEFV
HHHHCCCHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCCCCCCHHHCCCCHHHHHHH
GLLPNKSSNYLIKRVIGMPGDTVACCNVNGQVTVNGKALDERSYLYSENGEMVKPSAMEF
HCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEECCCEECCCCEEECCCCCEECCCCEEE
RVTVPRGRMFVLGDHRNASGDSRYHLQDLDPGEYTGAPAFVPLDDVVGPAKAILMPLNRI
EEECCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHH
EGLGTPDIFRGIPDRSSSAPGKARICVGNACCPK
CCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
ADDYRARRAANGDTRDSDDATARGEQASGWQRFRSGAIEVVLIVVGALIISAVLRGFVA
CCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QMFVIPSKSMQNTLQVGDRVIAVKAADFHRGDVVVFKDTEHWLPAAQDRRSVPGQILEFV
HHHHCCCHHHHHHHHHCCEEEEEEECCCCCCCEEEEECCCCCCCCCHHHCCCCHHHHHHH
GLLPNKSSNYLIKRVIGMPGDTVACCNVNGQVTVNGKALDERSYLYSENGEMVKPSAMEF
HCCCCCCCCHHHHHHHCCCCCEEEEEECCCEEEECCCEECCCCEEECCCCCEECCCCEEE
RVTVPRGRMFVLGDHRNASGDSRYHLQDLDPGEYTGAPAFVPLDDVVGPAKAILMPLNRI
EEECCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCEEEHHHHCCCHHHHHHHHHHH
EGLGTPDIFRGIPDRSSSAPGKARICVGNACCPK
CCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]