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The map label for this gene is infC

Identifier: 50842895

GI number: 50842895

Start: 1535354

End: 1536160

Strand: Reverse

Name: infC

Synonym: PPA1414

Alternate gene names: 50842895

Gene position: 1536160-1535354 (Counterclockwise)

Preceding gene: 50842896

Following gene: 50842894

Centisome position: 60.0

GC content: 59.36

Gene sequence:

>807_bases
ATGTGTGTACATCCCACGTGTCAGGTCTTCGCGCATTCGCGAGGGCCTTATTTTGTATCCGGATCGTGGAGGCGCAGTTA
TGCGCCACGATCTAAGAGAACAGACATCCGGGAGGACCCCATCAGTACTGAACCCCGCATCAACGAGCGGATTCGCGTTC
CCGAGGTGCGCCTGGTCGGCCCTAATGGCGAACAGGTCGGCATCGTCAGGGTCGAGCAGGCATTGCAACTTGCCCGCGAG
CAGGACCTCGACCTCGTCGAGGTGGCTCCGCAGGCCCGGCCCCCTGTCGTCAAGCTCATGGACTACGGCAAGTTCAAGTA
CGAGGCGGCCCAAAAGGCCCGGGAGTCACGACGCAACCAGGCGAACTCCATCATTAAGGAGATGAAGCTTCGTCCGAAGA
TTGATGACCACGATTATGAGACCAAGAAGGGCCACGTTCTGCGCTTCCTCAAGGCCGGGGACAAGGTCAAGATCACGATT
ATGTTCCGTGGTCGTGAGCAGTCTCGACCGGAGCTCGGGGTCAACCTGCTGCGTCGTCTTGCCGATGATCTGACTGAGTA
CGCGACCGTCGAGTCTCCTCCCAAACAGGAGGGCCGCAACATGCTCATGATCCTGGCTCCGACTCGTAAGAAGAACCAGG
CCAAGGCGGATCAGAAGGCTGAGCGTGACCGTCGCGCCGCTGAGCGTGCCGAGGCTGCTGAGGCTGATAAGGCCTACGAG
GCTGCGCAGCGGGCTGCTGCAGGCACTGCGAAGAAAAAGAAGAAGAAGGGTCCGGCCGACAATATGGATCCTGACATTGA
CCTCTGA

Upstream 100 bases:

>100_bases
ATCAGGGCAAAACTGGTCTTGCGTAAGCGGGGGCCTGACCTCCCACCTAGGCGGATTCCGTTCGCCGGGTTATGCTGATG
AGTTTCATCGGCTTGGCGGG

Downstream 100 bases:

>100_bases
GCGTTGCTCAGAACCTGGCGATCCGGTTTTCGCCGGTGAGCCAGCCCGGGACCTTCCCTCCGGTTCGCGGGACGACATAC
ATGAACGAATGGAGCTATCC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MCVHPTCQVFAHSRGPYFVSGSWRRSYAPRSKRTDIREDPISTEPRINERIRVPEVRLVGPNGEQVGIVRVEQALQLARE
QDLDLVEVAPQARPPVVKLMDYGKFKYEAAQKARESRRNQANSIIKEMKLRPKIDDHDYETKKGHVLRFLKAGDKVKITI
MFRGREQSRPELGVNLLRRLADDLTEYATVESPPKQEGRNMLMILAPTRKKNQAKADQKAERDRRAAERAEAAEADKAYE
AAQRAAAGTAKKKKKKGPADNMDPDIDL

Sequences:

>Translated_268_residues
MCVHPTCQVFAHSRGPYFVSGSWRRSYAPRSKRTDIREDPISTEPRINERIRVPEVRLVGPNGEQVGIVRVEQALQLARE
QDLDLVEVAPQARPPVVKLMDYGKFKYEAAQKARESRRNQANSIIKEMKLRPKIDDHDYETKKGHVLRFLKAGDKVKITI
MFRGREQSRPELGVNLLRRLADDLTEYATVESPPKQEGRNMLMILAPTRKKNQAKADQKAERDRRAAERAEAAEADKAYE
AAQRAAAGTAKKKKKKGPADNMDPDIDL
>Mature_268_residues
MCVHPTCQVFAHSRGPYFVSGSWRRSYAPRSKRTDIREDPISTEPRINERIRVPEVRLVGPNGEQVGIVRVEQALQLARE
QDLDLVEVAPQARPPVVKLMDYGKFKYEAAQKARESRRNQANSIIKEMKLRPKIDDHDYETKKGHVLRFLKAGDKVKITI
MFRGREQSRPELGVNLLRRLADDLTEYATVESPPKQEGRNMLMILAPTRKKNQAKADQKAERDRRAAERAEAAEADKAYE
AAQRAAAGTAKKKKKKGPADNMDPDIDL

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=50.2994011976048, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 30480; Mature: 30480

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVHPTCQVFAHSRGPYFVSGSWRRSYAPRSKRTDIREDPISTEPRINERIRVPEVRLVG
CCCCCCHHHEECCCCCEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
PNGEQVGIVRVEQALQLAREQDLDLVEVAPQARPPVVKLMDYGKFKYEAAQKARESRRNQ
CCCCEEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHH
ANSIIKEMKLRPKIDDHDYETKKGHVLRFLKAGDKVKITIMFRGREQSRPELGVNLLRRL
HHHHHHHHHCCCCCCCCCCCCCCCHHHHEECCCCEEEEEEEECCCCCCCHHHHHHHHHHH
ADDLTEYATVESPPKQEGRNMLMILAPTRKKNQAKADQKAERDRRAAERAEAAEADKAYE
HHHHHHHHCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQRAAAGTAKKKKKKGPADNMDPDIDL
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MCVHPTCQVFAHSRGPYFVSGSWRRSYAPRSKRTDIREDPISTEPRINERIRVPEVRLVG
CCCCCCHHHEECCCCCEEEECCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEC
PNGEQVGIVRVEQALQLAREQDLDLVEVAPQARPPVVKLMDYGKFKYEAAQKARESRRNQ
CCCCEEEHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHH
ANSIIKEMKLRPKIDDHDYETKKGHVLRFLKAGDKVKITIMFRGREQSRPELGVNLLRRL
HHHHHHHHHCCCCCCCCCCCCCCCHHHHEECCCCEEEEEEEECCCCCCCHHHHHHHHHHH
ADDLTEYATVESPPKQEGRNMLMILAPTRKKNQAKADQKAERDRRAAERAEAAEADKAYE
HHHHHHHHCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQRAAAGTAKKKKKKGPADNMDPDIDL
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]