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The map label for this gene is argJ

Identifier: 50842833

GI number: 50842833

Start: 1472853

End: 1473662

Strand: Reverse

Name: argJ

Synonym: PPA1349

Alternate gene names: 50842833

Gene position: 1473662-1472853 (Counterclockwise)

Preceding gene: 50842834

Following gene: 50842832

Centisome position: 57.56

GC content: 59.01

Gene sequence:

>810_bases
ATGTCGGTCACCTATCCACTCGGATTCCGCGCCGGGGGTATTCAGGCCGGGTTGCGAACCACCCCAGGCCTGGACCTTGC
ACTCATCGTCAACGATGGACCCGCCGACGTCGTTGCCGGGGTATTCACAACAAACCGCGTGTGCGCTGCGCCGGTCCAGT
GGTCGCGTCATGCCACTGCCGACCACAAGGCTCGTGCTGTCATTGTCAACGCGGCTGTCGCTAACGCCTGTACCGGGATC
GATGGCTTCGCCGACTGTGACATCACCTTCAGTCGGGTTGACTCCGATGCCTGCATGTCGACCAATGACACAGTTGTCGC
TATGGCCTCGGGGGCTTCCGGTATCAGCCTGACGGGTGATGAACTTACCGACGCACTCACCGAGCTGTGCGCCATCTTGG
CTCGCCAGCTTGTCGCAGATGCTGAGGGATCCCACCACGATGTCAAAGTGACCGTTACAGGTGCCATCAGTACCGAAGCT
GCTGTGGCGGTGGCCCGGGAGGTCACGCGTTCCAACCTCGTCAAAACGGCTATCGCAGGAAATGACCCCAACTGGGGTCG
CATCCTCGCGGCGATCGGATGTGTTCCCGAGAATGTAGCTCCCTTCGATCCCGACCAAGTGGATGTGTCTATCAATGACA
TCCAGATCTGTAAGGCCGGGGGTATCGGGGAGGACCGCAACCTCGTCGATATGAGGCCACGAGAGGTTCACATCGATATT
GAGCTGCATGCGGGTGACGCCGAAGCTGCGGTATGGACCAATGATCTGACCCACCAATACGTCGAAGAGAATAGCGCGTA
TACATCATGA

Upstream 100 bases:

>100_bases
GGACGGCTGGTGCCGTCATTCAATGTCTCAACGTGGCCTTTGGTCTCCCCGAGACTACGGGGTTGCCTCTCATTGGTCTT
AATCCGTGACAGGAGGATTC

Downstream 100 bases:

>100_bases
CCCTTGCTCTTGACATCCCCCTCAACGACACCCAGTTCTCGGCTCAGCGGAAATCTGAGGTCCTGGTAGAAGCGCTGCCT
TGGATCAGGCGGTTTCAGGG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSVTYPLGFRAGGIQAGLRTTPGLDLALIVNDGPADVVAGVFTTNRVCAAPVQWSRHATADHKARAVIVNAAVANACTGI
DGFADCDITFSRVDSDACMSTNDTVVAMASGASGISLTGDELTDALTELCAILARQLVADAEGSHHDVKVTVTGAISTEA
AVAVAREVTRSNLVKTAIAGNDPNWGRILAAIGCVPENVAPFDPDQVDVSINDIQICKAGGIGEDRNLVDMRPREVHIDI
ELHAGDAEAAVWTNDLTHQYVEENSAYTS

Sequences:

>Translated_269_residues
MSVTYPLGFRAGGIQAGLRTTPGLDLALIVNDGPADVVAGVFTTNRVCAAPVQWSRHATADHKARAVIVNAAVANACTGI
DGFADCDITFSRVDSDACMSTNDTVVAMASGASGISLTGDELTDALTELCAILARQLVADAEGSHHDVKVTVTGAISTEA
AVAVAREVTRSNLVKTAIAGNDPNWGRILAAIGCVPENVAPFDPDQVDVSINDIQICKAGGIGEDRNLVDMRPREVHIDI
ELHAGDAEAAVWTNDLTHQYVEENSAYTS
>Mature_268_residues
SVTYPLGFRAGGIQAGLRTTPGLDLALIVNDGPADVVAGVFTTNRVCAAPVQWSRHATADHKARAVIVNAAVANACTGID
GFADCDITFSRVDSDACMSTNDTVVAMASGASGISLTGDELTDALTELCAILARQLVADAEGSHHDVKVTVTGAISTEAA
VAVAREVTRSNLVKTAIAGNDPNWGRILAAIGCVPENVAPFDPDQVDVSINDIQICKAGGIGEDRNLVDMRPREVHIDIE
LHAGDAEAAVWTNDLTHQYVEENSAYTS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=200, Percent_Identity=33.5, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 28054; Mature: 27922

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTYPLGFRAGGIQAGLRTTPGLDLALIVNDGPADVVAGVFTTNRVCAAPVQWSRHATA
CEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHEEHHHHCCCEEECCCCCCCCCCC
DHKARAVIVNAAVANACTGIDGFADCDITFSRVDSDACMSTNDTVVAMASGASGISLTGD
CCCCEEEEEEEHHHHHHCCCCCCEECCEEEEECCCCHHCCCCCEEEEEECCCCCCEECHH
ELTDALTELCAILARQLVADAEGSHHDVKVTVTGAISTEAAVAVAREVTRSNLVKTAIAG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEEEEECC
NDPNWGRILAAIGCVPENVAPFDPDQVDVSINDIQICKAGGIGEDRNLVDMRPREVHIDI
CCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECEEEEEECCCCCCCCCEEECCCCEEEEEE
ELHAGDAEAAVWTNDLTHQYVEENSAYTS
EEECCCCCEEEEECHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVTYPLGFRAGGIQAGLRTTPGLDLALIVNDGPADVVAGVFTTNRVCAAPVQWSRHATA
EEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHEEHHHHCCCEEECCCCCCCCCCC
DHKARAVIVNAAVANACTGIDGFADCDITFSRVDSDACMSTNDTVVAMASGASGISLTGD
CCCCEEEEEEEHHHHHHCCCCCCEECCEEEEECCCCHHCCCCCEEEEEECCCCCCEECHH
ELTDALTELCAILARQLVADAEGSHHDVKVTVTGAISTEAAVAVAREVTRSNLVKTAIAG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHEEEEECC
NDPNWGRILAAIGCVPENVAPFDPDQVDVSINDIQICKAGGIGEDRNLVDMRPREVHIDI
CCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECEEEEEECCCCCCCCCEEECCCCEEEEEE
ELHAGDAEAAVWTNDLTHQYVEENSAYTS
EEECCCCCEEEEECHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]