Click here to switch to the map view.

The map label for this gene is mtrA [H]

Identifier: 50842818

GI number: 50842818

Start: 1460153

End: 1460863

Strand: Reverse

Name: mtrA [H]

Synonym: PPA1338

Alternate gene names: 50842818

Gene position: 1460863-1460153 (Counterclockwise)

Preceding gene: 50842819

Following gene: 50842817

Centisome position: 57.06

GC content: 59.35

Gene sequence:

>711_bases
GTGGACGCCGCCGGTGATCATGGGCCGATTCTTGTCGTTGACGACGACGCGGCCCTAGCGGAGATGCTTCAGCTTGTCCT
CATCAAAGAAGGGTTCTCGACGGCATGGGTCGGGCACGGCAGTGATGTCATGGACGTATTCCGCGAGCACCGGCCCGCCC
TGGTCCTTCTCGACCTCATGCTGCCCGGGCGTGACGGTATCCGGATCTGTCAGGACATCCGACGTGAGTCAGGCGTCCCG
ATCATCATGCTCACTGCCCGCACTGACACCCCTAATGTCGTCCAAGGACTTGGTGCTGGAGCCGACGACTACGTCTGTAA
GCCGTTCCGGTCCGCCGAGCTCATTGCTCGTATTCGTGCCCGGTTGCGCACACCCGTTTCCCGGCGTGAGGAGGGCGAGG
TCATTACCGTCGGGGATTTGACCATTGATCCCGTTGCCCATCTGGTTCAACTAGGAGGCGAGGAGATCTCACTCACTCCG
TTGGAATACTCCCTGCTCGTTACGATGGCCCAATACCCCAATAGGGTATTTAGCAGGGAGACCCTGTTGCGTGAGGTATG
GGGATACACCAACATCACCGATACTCGGTTGGTCAACGTCCATGTGCAGAGACTGCGTTCCAAGGTGGAGCGCAACGCGG
ACCACCCCCAGATGATCGTCACTGTTCGTGGCATCGGTTACCGCATCAACACCCCTGGGGAGGAAAGCTGA

Upstream 100 bases:

>100_bases
CTCGCAACGGCGACCGACACCCCTGCCCTCAACTGATCACCGGCCAGGAGTATGGGGGCTACCATATGCACCATCTCAGA
ATCCAGTCAGGAGGTCCACG

Downstream 100 bases:

>100_bases
TCACCCTGGCGGGGCGCGCCGGTCGTGGTTGGCGGCCGGGTTGGTGCCCATCGTGGCTGACCGGACCTCGACGGCTGTGG
TGGTCTTCCCTGCCGCTGCG

Product: putative response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MDAAGDHGPILVVDDDAALAEMLQLVLIKEGFSTAWVGHGSDVMDVFREHRPALVLLDLMLPGRDGIRICQDIRRESGVP
IIMLTARTDTPNVVQGLGAGADDYVCKPFRSAELIARIRARLRTPVSRREEGEVITVGDLTIDPVAHLVQLGGEEISLTP
LEYSLLVTMAQYPNRVFSRETLLREVWGYTNITDTRLVNVHVQRLRSKVERNADHPQMIVTVRGIGYRINTPGEES

Sequences:

>Translated_236_residues
MDAAGDHGPILVVDDDAALAEMLQLVLIKEGFSTAWVGHGSDVMDVFREHRPALVLLDLMLPGRDGIRICQDIRRESGVP
IIMLTARTDTPNVVQGLGAGADDYVCKPFRSAELIARIRARLRTPVSRREEGEVITVGDLTIDPVAHLVQLGGEEISLTP
LEYSLLVTMAQYPNRVFSRETLLREVWGYTNITDTRLVNVHVQRLRSKVERNADHPQMIVTVRGIGYRINTPGEES
>Mature_236_residues
MDAAGDHGPILVVDDDAALAEMLQLVLIKEGFSTAWVGHGSDVMDVFREHRPALVLLDLMLPGRDGIRICQDIRRESGVP
IIMLTARTDTPNVVQGLGAGADDYVCKPFRSAELIARIRARLRTPVSRREEGEVITVGDLTIDPVAHLVQLGGEEISLTP
LEYSLLVTMAQYPNRVFSRETLLREVWGYTNITDTRLVNVHVQRLRSKVERNADHPQMIVTVRGIGYRINTPGEES

Specific function: Member of the two-component regulatory system mtrA/mtrB [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=42.2222222222222, Blast_Score=170, Evalue=7e-44,
Organism=Escherichia coli, GI1788394, Length=219, Percent_Identity=36.986301369863, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=33.1818181818182, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=36.6071428571429, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=35.7466063348416, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=37.3873873873874, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=33.6322869955157, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=36.8888888888889, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=31.6239316239316, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=28.5087719298246, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=31.6964285714286, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=32.7868852459016, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=164, Percent_Identity=29.2682926829268, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26216; Mature: 26216

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAGDHGPILVVDDDAALAEMLQLVLIKEGFSTAWVGHGSDVMDVFREHRPALVLLDLM
CCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCEEEEEEEC
LPGRDGIRICQDIRRESGVPIIMLTARTDTPNVVQGLGAGADDYVCKPFRSAELIARIRA
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
RLRTPVSRREEGEVITVGDLTIDPVAHLVQLGGEEISLTPLEYSLLVTMAQYPNRVFSRE
HHCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCHHHHHHH
TLLREVWGYTNITDTRLVNVHVQRLRSKVERNADHPQMIVTVRGIGYRINTPGEES
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCC
>Mature Secondary Structure
MDAAGDHGPILVVDDDAALAEMLQLVLIKEGFSTAWVGHGSDVMDVFREHRPALVLLDLM
CCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCEEEEEEEC
LPGRDGIRICQDIRRESGVPIIMLTARTDTPNVVQGLGAGADDYVCKPFRSAELIARIRA
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
RLRTPVSRREEGEVITVGDLTIDPVAHLVQLGGEEISLTPLEYSLLVTMAQYPNRVFSRE
HHCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCHHHHHHH
TLLREVWGYTNITDTRLVNVHVQRLRSKVERNADHPQMIVTVRGIGYRINTPGEES
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]