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The map label for this gene is bacC [H]

Identifier: 50842768

GI number: 50842768

Start: 1395840

End: 1397579

Strand: Reverse

Name: bacC [H]

Synonym: PPA1287

Alternate gene names: 50842768

Gene position: 1397579-1395840 (Counterclockwise)

Preceding gene: 50842769

Following gene: 50842767

Centisome position: 54.59

GC content: 49.25

Gene sequence:

>1740_bases
ATGCAACCGTCACATGATTTGCTGGAGGGGTTTCGTAATATAGTCATTCAGAAACCAGGTGATGTCTGTCTGACCGGTCC
CGCCGGCGAGCAATGCTCATGGGAACAGCTAGTTAAAAATATCCTTGCGTGGAGAAGGTGGTTCAACCGAAAACAAAGTG
AGGGCGTTACTTTTGCTGCTCGACTCGATTTATCCGCCAAGTCTGTTGCCCTTATAATAGCAGCTGTGACGTTGCCTGTC
AAGATTGCTTGGATTCCGTTGAATATTCCGGCTTCACGAGAGCGGGACATGATTATTAATCTTGGGCCTAAAACGGTTCT
GATCGACGACTCAACAGCGGAAGAAGCGATTTTTGCAGGGAACTGGATAAGTGATGTCAGGTCCTTGACCTGGAGCGGTA
AATCAAAATTCTTATATTTCACATCTGGATCAGAAGGAGTTCCGAAAGCCGTCCAAGTAGGAATGGATGCGGTGCGGAAC
CGTATCACGTGGATGTGGAACGCCTACCCTTACGAGTCAAGCGATCTTGTGGTCGTCCAGAAGCCACTCTCATTTGTTGC
TTCATTTTGGGAAGTGTTGGGGACTCTGCTGGCAGGTGTTACTGGTGTTTTGATTACTAATATCGAGCGTAGCAGACCTG
ACGTGATGTTCGATCGACTTGCGTCTAGTGGTGCTACCCACCTTTTTACGACACCTCCAGCACTAGCCAGCTTGTGTGAC
ATTGCCACAGAGCAAGGGAGCACTCTTCCTCAGCTCCGTCTAGCGTGCAGCAGTGCAGACCAGCTGATGGCAAGCGTTGT
CCGTCAATTCTTCGAGATCGCGCCCCGTGCGCGAGTAGTGAATCTTTACGGAGCTACTGAGACGTCGGCTAACACAACAA
GTTTCGAGGTTTCTCGGTCAGGTAGCATTCCGGACCCTATCCCCCTTGGCGAGCCGATCTGTGCTACGAAAATTGTAATT
CGGGACATGAAAGGTAACGAAAAGTTATCTGGGGAAGAGGGGCAGATATGCGTACAGGGTGCCCCAGTGGCCGATGGATA
TATCGTTAATGGTCAACTCAGTCCAGGGGACGATGCGTTCTTTACACTTGGAAGTGGACAACGTGAAATACGGACTGGTG
ATCTGGGAATCATCAAGGATGGTGTCCTTTCACTGGTTGGCAGGCTCGATAATGCGGTAAATATCGCTGGATACAAGATC
CACTTGGAAGAGGTTGAAAGAGCTGCAGCTCGAGTTGCTAACTCCACGAAACAATGTGGTGCAGTTTATCACCAAGGCAG
TGGTGGATTTTTGGCGCTCGTGATTCCACGCGAATGGGAATCTCAGGTCACGACTTCTCGTCTTGCCGAATTTCTACCTT
CCTATATGATTCCTCTCAAGATCGTAACTACGCAGAATGTTCCTAGATCAAGAACGGGAAAAATCGATCGGAGCGAGTGC
CTGAAATTGGTAACACAGAGCGAACTCTACGATCACGACAGAATATCCCAAGGACAAATGCAGCGTAACAGTGTTCACGA
TCAAGTGCAAAATATCTGGGATATGGTCCTTGGAAAGAAGAGCCACGGTGAAGATCGTGATTTTTTCTCCGCAGGTGGAA
ATTCGTTGCGCGCTGTTCAGCTTTTGACCGCCATCGGTAAACAGTTTGGTGTTCGTGTCCCCTTGCGGAACTTCTATTCC
AATCCAACGATTTCCTGCTTGGTCAGCTTGCTGATGCCTGTTGAGGAGCGCGAGCAGTGA

Upstream 100 bases:

>100_bases
ACGACTGTCGCTAATGCCATAAAAACTGCCCTTAATGATTGTGATACATCTCAGATAACAATGCTCAAAAGCTATTGATG
TAGTATGAAGGGAAATAAAG

Downstream 100 bases:

>100_bases
ATCCGGAAGTTTGGCAGCGTATTAGTTCAGCAACTACCTCTTGTTGCTCCACAGTCCTGATATTCCCTCCTACGGGTGCC
GGAGCTCCTGCCTTTCAATC

Product: non-ribosomal peptide synthetase

Products: NA

Alternate protein names: BA3; ATP-dependent isoleucine adenylase; IleA; Isoleucine activase; ATP-dependent D-phenylalanine adenylase; D-PheA; D-phenylalanine activase; ATP-dependent histidine adenylase; HisA; Histidine activase; ATP-dependent D-aspartate adenylase; D-AspA; D-aspartate activase; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; Aspartate racemase; Phenylalanine racemase [ATP hydrolyzing] [H]

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MQPSHDLLEGFRNIVIQKPGDVCLTGPAGEQCSWEQLVKNILAWRRWFNRKQSEGVTFAARLDLSAKSVALIIAAVTLPV
KIAWIPLNIPASRERDMIINLGPKTVLIDDSTAEEAIFAGNWISDVRSLTWSGKSKFLYFTSGSEGVPKAVQVGMDAVRN
RITWMWNAYPYESSDLVVVQKPLSFVASFWEVLGTLLAGVTGVLITNIERSRPDVMFDRLASSGATHLFTTPPALASLCD
IATEQGSTLPQLRLACSSADQLMASVVRQFFEIAPRARVVNLYGATETSANTTSFEVSRSGSIPDPIPLGEPICATKIVI
RDMKGNEKLSGEEGQICVQGAPVADGYIVNGQLSPGDDAFFTLGSGQREIRTGDLGIIKDGVLSLVGRLDNAVNIAGYKI
HLEEVERAAARVANSTKQCGAVYHQGSGGFLALVIPREWESQVTTSRLAEFLPSYMIPLKIVTTQNVPRSRTGKIDRSEC
LKLVTQSELYDHDRISQGQMQRNSVHDQVQNIWDMVLGKKSHGEDRDFFSAGGNSLRAVQLLTAIGKQFGVRVPLRNFYS
NPTISCLVSLLMPVEEREQ

Sequences:

>Translated_579_residues
MQPSHDLLEGFRNIVIQKPGDVCLTGPAGEQCSWEQLVKNILAWRRWFNRKQSEGVTFAARLDLSAKSVALIIAAVTLPV
KIAWIPLNIPASRERDMIINLGPKTVLIDDSTAEEAIFAGNWISDVRSLTWSGKSKFLYFTSGSEGVPKAVQVGMDAVRN
RITWMWNAYPYESSDLVVVQKPLSFVASFWEVLGTLLAGVTGVLITNIERSRPDVMFDRLASSGATHLFTTPPALASLCD
IATEQGSTLPQLRLACSSADQLMASVVRQFFEIAPRARVVNLYGATETSANTTSFEVSRSGSIPDPIPLGEPICATKIVI
RDMKGNEKLSGEEGQICVQGAPVADGYIVNGQLSPGDDAFFTLGSGQREIRTGDLGIIKDGVLSLVGRLDNAVNIAGYKI
HLEEVERAAARVANSTKQCGAVYHQGSGGFLALVIPREWESQVTTSRLAEFLPSYMIPLKIVTTQNVPRSRTGKIDRSEC
LKLVTQSELYDHDRISQGQMQRNSVHDQVQNIWDMVLGKKSHGEDRDFFSAGGNSLRAVQLLTAIGKQFGVRVPLRNFYS
NPTISCLVSLLMPVEEREQ
>Mature_579_residues
MQPSHDLLEGFRNIVIQKPGDVCLTGPAGEQCSWEQLVKNILAWRRWFNRKQSEGVTFAARLDLSAKSVALIIAAVTLPV
KIAWIPLNIPASRERDMIINLGPKTVLIDDSTAEEAIFAGNWISDVRSLTWSGKSKFLYFTSGSEGVPKAVQVGMDAVRN
RITWMWNAYPYESSDLVVVQKPLSFVASFWEVLGTLLAGVTGVLITNIERSRPDVMFDRLASSGATHLFTTPPALASLCD
IATEQGSTLPQLRLACSSADQLMASVVRQFFEIAPRARVVNLYGATETSANTTSFEVSRSGSIPDPIPLGEPICATKIVI
RDMKGNEKLSGEEGQICVQGAPVADGYIVNGQLSPGDDAFFTLGSGQREIRTGDLGIIKDGVLSLVGRLDNAVNIAGYKI
HLEEVERAAARVANSTKQCGAVYHQGSGGFLALVIPREWESQVTTSRLAEFLPSYMIPLKIVTTQNVPRSRTGKIDRSEC
LKLVTQSELYDHDRISQGQMQRNSVHDQVQNIWDMVLGKKSHGEDRDFFSAGGNSLRAVQLLTAIGKQFGVRVPLRNFYS
NPTISCLVSLLMPVEEREQ

Specific function: Induces peptide synthesis, activates and incorporates five amino acids, forms a thiazoline ring between the first two amino acids and incoporates a D-glutamine in the fourth position [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=432, Percent_Identity=23.3796296296296, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1786801, Length=520, Percent_Identity=25, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788107, Length=397, Percent_Identity=23.1738035264484, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550940, Length=424, Percent_Identity=23.3490566037736, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564422, Length=492, Percent_Identity=21.9512195121951, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32564420, Length=492, Percent_Identity=21.9512195121951, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=448, Percent_Identity=24.3303571428571, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648676, Length=522, Percent_Identity=27.3946360153257, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24582852, Length=449, Percent_Identity=23.6080178173719, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: =5.1.1.13; =5.1.1.11 [H]

Molecular weight: Translated: 63429; Mature: 63429

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSHDLLEGFRNIVIQKPGDVCLTGPAGEQCSWEQLVKNILAWRRWFNRKQSEGVTFAA
CCCCHHHHHHHHHHEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
RLDLSAKSVALIIAAVTLPVKIAWIPLNIPASRERDMIINLGPKTVLIDDSTAEEAIFAG
EECCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCHHEECC
NWISDVRSLTWSGKSKFLYFTSGSEGVPKAVQVGMDAVRNRITWMWNAYPYESSDLVVVQ
CHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEE
KPLSFVASFWEVLGTLLAGVTGVLITNIERSRPDVMFDRLASSGATHLFTTPPALASLCD
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHH
IATEQGSTLPQLRLACSSADQLMASVVRQFFEIAPRARVVNLYGATETSANTTSFEVSRS
HHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECC
GSIPDPIPLGEPICATKIVIRDMKGNEKLSGEEGQICVQGAPVADGYIVNGQLSPGDDAF
CCCCCCCCCCCCHHHHHHHEEECCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCE
FTLGSGQREIRTGDLGIIKDGVLSLVGRLDNAVNIAGYKIHLEEVERAAARVANSTKQCG
EEECCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHCCHHHHC
AVYHQGSGGFLALVIPREWESQVTTSRLAEFLPSYMIPLKIVTTQNVPRSRTGKIDRSEC
CEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHH
LKLVTQSELYDHDRISQGQMQRNSVHDQVQNIWDMVLGKKSHGEDRDFFSAGGNSLRAVQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHH
LLTAIGKQFGVRVPLRNFYSNPTISCLVSLLMPVEEREQ
HHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MQPSHDLLEGFRNIVIQKPGDVCLTGPAGEQCSWEQLVKNILAWRRWFNRKQSEGVTFAA
CCCCHHHHHHHHHHEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
RLDLSAKSVALIIAAVTLPVKIAWIPLNIPASRERDMIINLGPKTVLIDDSTAEEAIFAG
EECCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCHHEECC
NWISDVRSLTWSGKSKFLYFTSGSEGVPKAVQVGMDAVRNRITWMWNAYPYESSDLVVVQ
CHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEE
KPLSFVASFWEVLGTLLAGVTGVLITNIERSRPDVMFDRLASSGATHLFTTPPALASLCD
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHH
IATEQGSTLPQLRLACSSADQLMASVVRQFFEIAPRARVVNLYGATETSANTTSFEVSRS
HHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEECC
GSIPDPIPLGEPICATKIVIRDMKGNEKLSGEEGQICVQGAPVADGYIVNGQLSPGDDAF
CCCCCCCCCCCCHHHHHHHEEECCCCCCCCCCCCCEEEECCCCCCCEEEECCCCCCCCCE
FTLGSGQREIRTGDLGIIKDGVLSLVGRLDNAVNIAGYKIHLEEVERAAARVANSTKQCG
EEECCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHCCHHHHC
AVYHQGSGGFLALVIPREWESQVTTSRLAEFLPSYMIPLKIVTTQNVPRSRTGKIDRSEC
CEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHH
LKLVTQSELYDHDRISQGQMQRNSVHDQVQNIWDMVLGKKSHGEDRDFFSAGGNSLRAVQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHH
LLTAIGKQFGVRVPLRNFYSNPTISCLVSLLMPVEEREQ
HHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9427658 [H]