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The map label for this gene is lgrC [H]

Identifier: 50842769

GI number: 50842769

Start: 1397602

End: 1400898

Strand: Reverse

Name: lgrC [H]

Synonym: PPA1288

Alternate gene names: 50842769

Gene position: 1400898-1397602 (Counterclockwise)

Preceding gene: 50842770

Following gene: 50842768

Centisome position: 54.72

GC content: 46.01

Gene sequence:

>3297_bases
GTGATAAACCTTACCAAAAGTTTGGAAAAAAATGGGTTGAGCTTGCTCGCTACCGGGAGTGCACTGGTCGGGGAAAACGT
CGACTGGCCTTTAGAACGCACACTCTACTCGTATTTAGTTGAATGGGCCCAGATCACTTCACATCACGTTGCCGTAATAG
ATATTCATGGTGAAGAAATCACCTACGAAATGTTATTGAATCGAGTTAACAATCGAGCCTATCTCTTGGAAAAGAAACAT
GCCTTTGGGAGGGTAGTCATTTCAGAGCACTTGCGCGGTATCGAATGTCTTGTCGATATCCTAGCTTGTAGTGCCGCAGG
TGCCATCTATACACCCATTGATCCTCAGTGGCCAGAGGCTCGTCGTAAACATATTAAGACGATCACGAACGCGGCCGCCA
TTTTCACTGAAAATACCTCGCACGTAACGGAAGCAAAGGCACCATTAGGAGTCACATTTCTGGAGCGTGTGGATGATCCT
TTCAACACTCCAAGCTACTGCTTTTTCACCTCGGGTAGCGCAGGTGAACCGAAAGGTGCGCTAATCGCGCATATGGGCAT
GATGAATCACTTGCATAGCAAAGCCCATCTCCTTCATCTTGGTGCTGACTCAGTTGTGGCCCAGACGGCACCCACCACCT
TTGATGTATCCATTTGGCAATTTTGCTCAGCCTTACTGGTAGGCGGTGCAGTACGTATCGTCCCCAACGGTATTTCACAG
GATCCGCATGAGCTTTTTTCTTTACTGAAAGAGAAACATATAACACACATTGAACTAGTTCCGACAGTATTTCGTGAACT
TATTCACGAAATCGGGCCAAGCGTGTCTTTCTCTGGGCTTGAGTATGTTCTGGTGACTGGCGAAGAATTACCCCTTCGGT
TGGCTAAAGACTGGGCAGAAAAATTCCCGTCTGTCCCGTTAATTAATGCGTATGGTCCTACGGAATGTTCTGACGATGTA
ACGCATGCGATCGTGGATGGCGAATCGCTTAACTCAGGTGAAGTTCCCATCGGAATTCCAATACCTAATGCGTCTTTATA
CGTCCTAGAGTATGCAGAAGGTACTTGGCGTCCAGTTCCTCCTGGAGCGCAAGGTGAGCTTTTTGTTGCTGGTCTTTGTG
TGGGTTTAGGTTATATCGGAAGCCCAGATAAAACCGCTCAAGCATTTGCCAGGATTGACGGATACCCATTCCGAATATAC
CGCACCGGAGATCTCGTTCACCAGCGAGCGGATAGTCAACTGGTTTACGATGGCCGCGCTGATCGACAGATAAAAATTAG
TGGAGTACGGATTGAGCCCGGTGAAATCGAGAACCGTATCCTTCAAGAAATCCCAGAGCTTGAAGACGTTGTAGTAGTTA
AATTCCACCCTCGTGTCCGTGAACGTCGCGCAATGGTGCTCCGAGAAACGACGCACCAGTTTCTTCGCCAAGGAGACGCT
AGCTTGGCTGCATTCTATCTTCCTCGCGCCGATTGTTTAGTTACTCCCAAAATGCTTAATAATCGCGCGAAAAGCAGTCT
CCCGAGAGTGATGTGTCCATCCCGTTGGATAGAGGTTACTGATATTCCCACTACTTCAAATGGCAAGGTAGATATTAAGT
TATTAGAGCGCCGTGCTGGGGAACTGTTACTGAATGAAATTCAAGAGTCAAGAGAGGGATCCATTCCCGGTAGAGTTGAA
CAGAATCAGGACTCTTTCATTCTTCTCGTTCAGGACGTGCTTGGCACTCCTGTGAATCCAGAACTAACATTTATCGAATC
CGGAGGCGATTCTCTTCGAGCAATTCAGCTAGCCAATATTGTCCGCTCACGAGGATCTTACGTAAGAGTACGAGATTTGC
TTTCTTCATATACGTTAGGCTCTCTAGCAAAAGAATATCAAGCACAACAGATATCTCCGAAGAAATCGACCTCTGCAAAA
AGATCTCCTTCCCGCTTTGATGACGTCAAAATTCCTTTGACTTGTGACATGAATCCGGCTCAGCAAGGAATTTATTTTCA
ATGGCTACTGGAGCCTGAAAGCCCTTACTATAATTATCAGATATTGTTAGAATGCGCTGGGTCGAACACCGATAGAATCC
GTCGTGCTCTTGGCCAGGCATTACGGGCGAATCCACAGCTAATGGCGAAGTTTGGAGTGGATTCAACTGGGAGATTTACA
CAGACGTTTCCTATCTCTGCTATCGATATGGATGAAATCTCAATACACGAAGTGGCCTCTGCGCAAGAGGCTCGTAAGAT
CTGTTGGATGAAAGCAGCAGTCCCTTTTAACCTGGAGGAAGGTCCCGCTATCGCCGTGGACGAGATCCGTATAAATGGAT
ATTCTACCTGGTTCGTTTTGACCATGAACGAGATCCTTATCGATGGCTGGGGAGCAATGAAGTTCATGGAACAGTTAATT
TCTCTTTTTGAGTGTCGTAACATGGACGATCAGGAGATCGAAGTCAAGACAGCTATGACTTCAGCTCTGGAATATTTCCA
ACATCTGTCGAAACCTGAAGAGATATCCGCTGAAGCACGAGAATTTTGGTCAAAATCACTCGATGGAGTGAAATCATGTT
TCCCATTGCGCGATACATTAAATAGTTCGTGTGATCCCTACGCTGCTTCTGTTATAGAGGTCTCTCTAGATGACGAAGCG
ACTGCTGAGATCCGTTCCACTGCGCATGCATTGAGTACAAGCCCATTTGCAGTATTTGTGGCTGCTTATTCGTTAGCGTT
GGCAGCGGTCTCTGACCAACATGATTTTGTTGTCGGTGCACCAGTAGCAGGGCGAAACGATGAGTATAAAATTGGCGTCC
CAACTCTGATGCTTAACATGATTGCAATACGAACTCGTATAGATGTCGAAAAGAAAATTAGTGACACAGTACGTTCGATG
ATATCTAATGTGACTGAAGCTGTCTCATTCGGTGACAGCGTATTTAGCAAGGTTGTTTCTGAGTTCGCTGATCACACGAA
CGAGGATCCATTGTTTAGCACGATGGTTAATATGCTTACTTACCCGTCTCTGGAGTTTTGGGATGGTGATCGAAGCCTTC
ACTTAACTGAATTGAATACTGGGTTTACGAAATATGATGCGTCTCTTTATATCCAGCGACACGGCGAAGATTATACCTTG
CAACTTGCTTATAAAGTGGCGTATGTGACACCAGAACGCGCTAATAAAGTACTGGCTCTTACAGCGTGGTTCCTTACCTC
TGATTGGCTCTCGGGGAAGACGACTGTCGCTAATGCCATAAAAACTGCCCTTAATGATTGTGATACATCTCAGATAACAA
TGCTCAAAAGCTATTGA

Upstream 100 bases:

>100_bases
GACCTTGCTGTTGCTCAAAGCTTGTACGAGCACGTTCAAATATCCGGCGATGGATTACGTGTTCCAGACTTTCACGGAGA
CATGAAACGGTGAATATAGA

Downstream 100 bases:

>100_bases
TGTAGTATGAAGGGAAATAAAGATGCAACCGTCACATGATTTGCTGGAGGGGTTTCGTAATATAGTCATTCAGAAACCAG
GTGATGTCTGTCTGACCGGT

Product: surfactin synthetase subunit 1

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1098; Mature: 1098

Protein sequence:

>1098_residues
MINLTKSLEKNGLSLLATGSALVGENVDWPLERTLYSYLVEWAQITSHHVAVIDIHGEEITYEMLLNRVNNRAYLLEKKH
AFGRVVISEHLRGIECLVDILACSAAGAIYTPIDPQWPEARRKHIKTITNAAAIFTENTSHVTEAKAPLGVTFLERVDDP
FNTPSYCFFTSGSAGEPKGALIAHMGMMNHLHSKAHLLHLGADSVVAQTAPTTFDVSIWQFCSALLVGGAVRIVPNGISQ
DPHELFSLLKEKHITHIELVPTVFRELIHEIGPSVSFSGLEYVLVTGEELPLRLAKDWAEKFPSVPLINAYGPTECSDDV
THAIVDGESLNSGEVPIGIPIPNASLYVLEYAEGTWRPVPPGAQGELFVAGLCVGLGYIGSPDKTAQAFARIDGYPFRIY
RTGDLVHQRADSQLVYDGRADRQIKISGVRIEPGEIENRILQEIPELEDVVVVKFHPRVRERRAMVLRETTHQFLRQGDA
SLAAFYLPRADCLVTPKMLNNRAKSSLPRVMCPSRWIEVTDIPTTSNGKVDIKLLERRAGELLLNEIQESREGSIPGRVE
QNQDSFILLVQDVLGTPVNPELTFIESGGDSLRAIQLANIVRSRGSYVRVRDLLSSYTLGSLAKEYQAQQISPKKSTSAK
RSPSRFDDVKIPLTCDMNPAQQGIYFQWLLEPESPYYNYQILLECAGSNTDRIRRALGQALRANPQLMAKFGVDSTGRFT
QTFPISAIDMDEISIHEVASAQEARKICWMKAAVPFNLEEGPAIAVDEIRINGYSTWFVLTMNEILIDGWGAMKFMEQLI
SLFECRNMDDQEIEVKTAMTSALEYFQHLSKPEEISAEAREFWSKSLDGVKSCFPLRDTLNSSCDPYAASVIEVSLDDEA
TAEIRSTAHALSTSPFAVFVAAYSLALAAVSDQHDFVVGAPVAGRNDEYKIGVPTLMLNMIAIRTRIDVEKKISDTVRSM
ISNVTEAVSFGDSVFSKVVSEFADHTNEDPLFSTMVNMLTYPSLEFWDGDRSLHLTELNTGFTKYDASLYIQRHGEDYTL
QLAYKVAYVTPERANKVLALTAWFLTSDWLSGKTTVANAIKTALNDCDTSQITMLKSY

Sequences:

>Translated_1098_residues
MINLTKSLEKNGLSLLATGSALVGENVDWPLERTLYSYLVEWAQITSHHVAVIDIHGEEITYEMLLNRVNNRAYLLEKKH
AFGRVVISEHLRGIECLVDILACSAAGAIYTPIDPQWPEARRKHIKTITNAAAIFTENTSHVTEAKAPLGVTFLERVDDP
FNTPSYCFFTSGSAGEPKGALIAHMGMMNHLHSKAHLLHLGADSVVAQTAPTTFDVSIWQFCSALLVGGAVRIVPNGISQ
DPHELFSLLKEKHITHIELVPTVFRELIHEIGPSVSFSGLEYVLVTGEELPLRLAKDWAEKFPSVPLINAYGPTECSDDV
THAIVDGESLNSGEVPIGIPIPNASLYVLEYAEGTWRPVPPGAQGELFVAGLCVGLGYIGSPDKTAQAFARIDGYPFRIY
RTGDLVHQRADSQLVYDGRADRQIKISGVRIEPGEIENRILQEIPELEDVVVVKFHPRVRERRAMVLRETTHQFLRQGDA
SLAAFYLPRADCLVTPKMLNNRAKSSLPRVMCPSRWIEVTDIPTTSNGKVDIKLLERRAGELLLNEIQESREGSIPGRVE
QNQDSFILLVQDVLGTPVNPELTFIESGGDSLRAIQLANIVRSRGSYVRVRDLLSSYTLGSLAKEYQAQQISPKKSTSAK
RSPSRFDDVKIPLTCDMNPAQQGIYFQWLLEPESPYYNYQILLECAGSNTDRIRRALGQALRANPQLMAKFGVDSTGRFT
QTFPISAIDMDEISIHEVASAQEARKICWMKAAVPFNLEEGPAIAVDEIRINGYSTWFVLTMNEILIDGWGAMKFMEQLI
SLFECRNMDDQEIEVKTAMTSALEYFQHLSKPEEISAEAREFWSKSLDGVKSCFPLRDTLNSSCDPYAASVIEVSLDDEA
TAEIRSTAHALSTSPFAVFVAAYSLALAAVSDQHDFVVGAPVAGRNDEYKIGVPTLMLNMIAIRTRIDVEKKISDTVRSM
ISNVTEAVSFGDSVFSKVVSEFADHTNEDPLFSTMVNMLTYPSLEFWDGDRSLHLTELNTGFTKYDASLYIQRHGEDYTL
QLAYKVAYVTPERANKVLALTAWFLTSDWLSGKTTVANAIKTALNDCDTSQITMLKSY
>Mature_1098_residues
MINLTKSLEKNGLSLLATGSALVGENVDWPLERTLYSYLVEWAQITSHHVAVIDIHGEEITYEMLLNRVNNRAYLLEKKH
AFGRVVISEHLRGIECLVDILACSAAGAIYTPIDPQWPEARRKHIKTITNAAAIFTENTSHVTEAKAPLGVTFLERVDDP
FNTPSYCFFTSGSAGEPKGALIAHMGMMNHLHSKAHLLHLGADSVVAQTAPTTFDVSIWQFCSALLVGGAVRIVPNGISQ
DPHELFSLLKEKHITHIELVPTVFRELIHEIGPSVSFSGLEYVLVTGEELPLRLAKDWAEKFPSVPLINAYGPTECSDDV
THAIVDGESLNSGEVPIGIPIPNASLYVLEYAEGTWRPVPPGAQGELFVAGLCVGLGYIGSPDKTAQAFARIDGYPFRIY
RTGDLVHQRADSQLVYDGRADRQIKISGVRIEPGEIENRILQEIPELEDVVVVKFHPRVRERRAMVLRETTHQFLRQGDA
SLAAFYLPRADCLVTPKMLNNRAKSSLPRVMCPSRWIEVTDIPTTSNGKVDIKLLERRAGELLLNEIQESREGSIPGRVE
QNQDSFILLVQDVLGTPVNPELTFIESGGDSLRAIQLANIVRSRGSYVRVRDLLSSYTLGSLAKEYQAQQISPKKSTSAK
RSPSRFDDVKIPLTCDMNPAQQGIYFQWLLEPESPYYNYQILLECAGSNTDRIRRALGQALRANPQLMAKFGVDSTGRFT
QTFPISAIDMDEISIHEVASAQEARKICWMKAAVPFNLEEGPAIAVDEIRINGYSTWFVLTMNEILIDGWGAMKFMEQLI
SLFECRNMDDQEIEVKTAMTSALEYFQHLSKPEEISAEAREFWSKSLDGVKSCFPLRDTLNSSCDPYAASVIEVSLDDEA
TAEIRSTAHALSTSPFAVFVAAYSLALAAVSDQHDFVVGAPVAGRNDEYKIGVPTLMLNMIAIRTRIDVEKKISDTVRSM
ISNVTEAVSFGDSVFSKVVSEFADHTNEDPLFSTMVNMLTYPSLEFWDGDRSLHLTELNTGFTKYDASLYIQRHGEDYTL
QLAYKVAYVTPERANKVLALTAWFLTSDWLSGKTTVANAIKTALNDCDTSQITMLKSY

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=478, Percent_Identity=25.1046025104602, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI42544132, Length=304, Percent_Identity=26.9736842105263, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI156151445, Length=385, Percent_Identity=24.4155844155844, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI38505220, Length=383, Percent_Identity=25.065274151436, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI58082049, Length=373, Percent_Identity=24.6648793565684, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI122937307, Length=302, Percent_Identity=27.4834437086093, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI157311624, Length=371, Percent_Identity=24.5283018867925, Blast_Score=69, Evalue=3e-11,
Organism=Homo sapiens, GI157311622, Length=371, Percent_Identity=24.5283018867925, Blast_Score=69, Evalue=3e-11,
Organism=Homo sapiens, GI187761345, Length=407, Percent_Identity=24.3243243243243, Blast_Score=68, Evalue=4e-11,
Organism=Homo sapiens, GI187761343, Length=407, Percent_Identity=24.3243243243243, Blast_Score=68, Evalue=4e-11,
Organism=Homo sapiens, GI115511026, Length=383, Percent_Identity=24.0208877284595, Blast_Score=68, Evalue=5e-11,
Organism=Escherichia coli, GI1786801, Length=638, Percent_Identity=28.2131661442006, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI145693145, Length=561, Percent_Identity=23.3511586452763, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1788107, Length=301, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556356, Length=550, Percent_Identity=25.4545454545455, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560308, Length=308, Percent_Identity=26.2987012987013, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559526, Length=393, Percent_Identity=23.4096692111959, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564422, Length=473, Percent_Identity=22.6215644820296, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32564420, Length=473, Percent_Identity=22.6215644820296, Blast_Score=68, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=643, Percent_Identity=20.99533437014, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648676, Length=625, Percent_Identity=27.2, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24582852, Length=297, Percent_Identity=27.9461279461279, Blast_Score=74, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 121953; Mature: 121953

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLTKSLEKNGLSLLATGSALVGENVDWPLERTLYSYLVEWAQITSHHVAVIDIHGEEI
CCCCHHHHHHCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
TYEMLLNRVNNRAYLLEKKHAFGRVVISEHLRGIECLVDILACSAAGAIYTPIDPQWPEA
HHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHH
RRKHIKTITNAAAIFTENTSHVTEAKAPLGVTFLERVDDPFNTPSYCFFTSGSAGEPKGA
HHHHHHHHHHHHEEEECCCCHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCH
LIAHMGMMNHLHSKAHLLHLGADSVVAQTAPTTFDVSIWQFCSALLVGGAVRIVPNGISQ
HHHHHHHHHHHHCHHEEEEECCCHHHHCCCCCEECHHHHHHHHHHHHCCEEEEECCCCCC
DPHELFSLLKEKHITHIELVPTVFRELIHEIGPSVSFSGLEYVLVTGEELPLRLAKDWAE
CHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEECCEEEEEEECCCCCHHHHHHHHH
KFPSVPLINAYGPTECSDDVTHAIVDGESLNSGEVPIGIPIPNASLYVLEYAEGTWRPVP
HCCCCCEEECCCCCCCCCCHHEEEECCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCC
PGAQGELFVAGLCVGLGYIGSPDKTAQAFARIDGYPFRIYRTGDLVHQRADSQLVYDGRA
CCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHCCCCEEEEEECHHHHHHCCCCCEEECCCC
DRQIKISGVRIEPGEIENRILQEIPELEDVVVVKFHPRVRERRAMVLRETTHQFLRQGDA
CCEEEEEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
SLAAFYLPRADCLVTPKMLNNRAKSSLPRVMCPSRWIEVTDIPTTSNGKVDIKLLERRAG
CEEEEECCCCCCEECHHHHHCHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEHHHHHH
ELLLNEIQESREGSIPGRVEQNQDSFILLVQDVLGTPVNPELTFIESGGDSLRAIQLANI
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEECCCCCHHHHHHHHH
VRSRGSYVRVRDLLSSYTLGSLAKEYQAQQISPKKSTSAKRSPSRFDDVKIPLTCDMNPA
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCH
QQGIYFQWLLEPESPYYNYQILLECAGSNTDRIRRALGQALRANPQLMAKFGVDSTGRFT
HCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
QTFPISAIDMDEISIHEVASAQEARKICWMKAAVPFNLEEGPAIAVDEIRINGYSTWFVL
EECCCEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEEECCEEEEEEE
TMNEILIDGWGAMKFMEQLISLFECRNMDDQEIEVKTAMTSALEYFQHLSKPEEISAEAR
EEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EFWSKSLDGVKSCFPLRDTLNSSCDPYAASVIEVSLDDEATAEIRSTAHALSTSPFAVFV
HHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHH
AAYSLALAAVSDQHDFVVGAPVAGRNDEYKIGVPTLMLNMIAIRTRIDVEKKISDTVRSM
HHHHHHHHHCCCCCCEEEECCCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ISNVTEAVSFGDSVFSKVVSEFADHTNEDPLFSTMVNMLTYPSLEFWDGDRSLHLTELNT
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCC
GFTKYDASLYIQRHGEDYTLQLAYKVAYVTPERANKVLALTAWFLTSDWLSGKTTVANAI
CCEEECEEEEEEECCCCEEEEEEEEEEEECHHHCCCEEEEEEEHHHHHCCCCCHHHHHHH
KTALNDCDTSQITMLKSY
HHHHHCCCCCCEEEEECC
>Mature Secondary Structure
MINLTKSLEKNGLSLLATGSALVGENVDWPLERTLYSYLVEWAQITSHHVAVIDIHGEEI
CCCCHHHHHHCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
TYEMLLNRVNNRAYLLEKKHAFGRVVISEHLRGIECLVDILACSAAGAIYTPIDPQWPEA
HHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHH
RRKHIKTITNAAAIFTENTSHVTEAKAPLGVTFLERVDDPFNTPSYCFFTSGSAGEPKGA
HHHHHHHHHHHHEEEECCCCHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCH
LIAHMGMMNHLHSKAHLLHLGADSVVAQTAPTTFDVSIWQFCSALLVGGAVRIVPNGISQ
HHHHHHHHHHHHCHHEEEEECCCHHHHCCCCCEECHHHHHHHHHHHHCCEEEEECCCCCC
DPHELFSLLKEKHITHIELVPTVFRELIHEIGPSVSFSGLEYVLVTGEELPLRLAKDWAE
CHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCEECCEEEEEEECCCCCHHHHHHHHH
KFPSVPLINAYGPTECSDDVTHAIVDGESLNSGEVPIGIPIPNASLYVLEYAEGTWRPVP
HCCCCCEEECCCCCCCCCCHHEEEECCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCC
PGAQGELFVAGLCVGLGYIGSPDKTAQAFARIDGYPFRIYRTGDLVHQRADSQLVYDGRA
CCCCCCEEEEEHHHHCCCCCCCCHHHHHHHHCCCCEEEEEECHHHHHHCCCCCEEECCCC
DRQIKISGVRIEPGEIENRILQEIPELEDVVVVKFHPRVRERRAMVLRETTHQFLRQGDA
CCEEEEEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
SLAAFYLPRADCLVTPKMLNNRAKSSLPRVMCPSRWIEVTDIPTTSNGKVDIKLLERRAG
CEEEEECCCCCCEECHHHHHCHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEEHHHHHH
ELLLNEIQESREGSIPGRVEQNQDSFILLVQDVLGTPVNPELTFIESGGDSLRAIQLANI
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCEEEEECCCCCHHHHHHHHH
VRSRGSYVRVRDLLSSYTLGSLAKEYQAQQISPKKSTSAKRSPSRFDDVKIPLTCDMNPA
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCH
QQGIYFQWLLEPESPYYNYQILLECAGSNTDRIRRALGQALRANPQLMAKFGVDSTGRFT
HCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
QTFPISAIDMDEISIHEVASAQEARKICWMKAAVPFNLEEGPAIAVDEIRINGYSTWFVL
EECCCEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEEECCEEEEEEE
TMNEILIDGWGAMKFMEQLISLFECRNMDDQEIEVKTAMTSALEYFQHLSKPEEISAEAR
EEEHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EFWSKSLDGVKSCFPLRDTLNSSCDPYAASVIEVSLDDEATAEIRSTAHALSTSPFAVFV
HHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHH
AAYSLALAAVSDQHDFVVGAPVAGRNDEYKIGVPTLMLNMIAIRTRIDVEKKISDTVRSM
HHHHHHHHHCCCCCCEEEECCCCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ISNVTEAVSFGDSVFSKVVSEFADHTNEDPLFSTMVNMLTYPSLEFWDGDRSLHLTELNT
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCC
GFTKYDASLYIQRHGEDYTLQLAYKVAYVTPERANKVLALTAWFLTSDWLSGKTTVANAI
CCEEECEEEEEEECCCCEEEEEEEEEEEECHHHCCCEEEEEEEHHHHHCCCCCHHHHHHH
KTALNDCDTSQITMLKSY
HHHHHCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA