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The map label for this gene is thrC [H]

Identifier: 50842735

GI number: 50842735

Start: 1360591

End: 1361661

Strand: Reverse

Name: thrC [H]

Synonym: PPA1257

Alternate gene names: 50842735

Gene position: 1361661-1360591 (Counterclockwise)

Preceding gene: 50842736

Following gene: 50842734

Centisome position: 53.18

GC content: 59.29

Gene sequence:

>1071_bases
ATGAGCCAGCAGAATCGTCTCTTCGGCGTGATTGAGACCTATCGAGACCGTCTCCCTATGGACGGAATTGACCAGATCGT
GACGTTGGGGGAGGGGGCGACCCCGTTGGTGCCTGCCCCACGATTGGGCGCCGAGCTTGACGCGACGGTATGGGTTAAAG
TTGAAGGGGCCAATCCGACCGGATCGTTCAAGGATCGTGGCATGACGATGGCCATGACGAAAGCCCTTGCCGACGGCTCG
AAAGCCGTGGTGTGTGCCTCTACCGGTAATACCTCTGCCTCGGCATCGGCTTACGCCTCCCGAGCCGGCATGACTCCGGT
CGTGCTCCTTCCCCAGGGCAAGATTGCAGCTGGCAAACTCGCCCAGGCTGTTGTCCATGGCGGTCGAATCATCCAGATTC
TCGGCAACTTCGACGATTGCCTGCGTATTGCCCGCGAGCTGGCCGAGAATTTCCCGGTCTCCCTGGTGAACTCGATCAAT
CCGTACCGCATCGAGGGACAGAAAACTGCTGCCTTTGAGGTCGTTGACGTTCTTGGTGACGCTCCTGATATCCACGCTCT
TCCGGTGGGCAACGCAGGCAATATCACCGCCTATTGGAAGGGTTACCGCGAGTACGTAGCGGACGGTCCTGCCAGCCACA
CGCCGCGGATGTTCGGATTCCAAGCCGCTGGCGCAGCCCCCCTGGTGCTGGGCCACGACGTTAATGACCCGGAAACGGTA
GCCACCGCTATTCGTATCGGTCGTCCGGCCTCCGGCAAGCTGGCGTTGGCCGCTCGAGACGAGTCGGAGGGGCTCATCGA
CGCTGTCACGGACGAGCAAATTCTTGACGCCCAGACTTTCCTAGCTGCTCGAGAGGGCATTTTTGTTGAGCCGGCATCAG
CAGTCGGAGTGGCAGGTTTGTTCAAGTTGAAGTCCGAGGGACGCCTGGATCCTGGACTGCGCATCGTCGTCACGGTAACT
GGAAACGGTCTGAAGGACATTGACACTGCATTGAGTCGCACTACCTTGTCAACCGAGGCTGTGGAAGCTTCGACTGACCA
GGTTGCCGCTTTGTTGGACTTCTGTTCCTGA

Upstream 100 bases:

>100_bases
AAGCCCGAGAATGTGACGTCGACGAGTGCGTCAACGAACTCACCGGCCATCACTACGTCAACTCCGATCCTCGTGTTATC
CGAGTGGAGGGAATGTGATC

Downstream 100 bases:

>100_bases
GGAATTGACGATGGACAACAGCGTGCGGGTGCGTGTTCCCGCTACTTCTGCGAACCTCGGTCCCGGTTATGACTGTATCG
GCTTAGCTCTGGATCTATGG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSQQNRLFGVIETYRDRLPMDGIDQIVTLGEGATPLVPAPRLGAELDATVWVKVEGANPTGSFKDRGMTMAMTKALADGS
KAVVCASTGNTSASASAYASRAGMTPVVLLPQGKIAAGKLAQAVVHGGRIIQILGNFDDCLRIARELAENFPVSLVNSIN
PYRIEGQKTAAFEVVDVLGDAPDIHALPVGNAGNITAYWKGYREYVADGPASHTPRMFGFQAAGAAPLVLGHDVNDPETV
ATAIRIGRPASGKLALAARDESEGLIDAVTDEQILDAQTFLAAREGIFVEPASAVGVAGLFKLKSEGRLDPGLRIVVTVT
GNGLKDIDTALSRTTLSTEAVEASTDQVAALLDFCS

Sequences:

>Translated_356_residues
MSQQNRLFGVIETYRDRLPMDGIDQIVTLGEGATPLVPAPRLGAELDATVWVKVEGANPTGSFKDRGMTMAMTKALADGS
KAVVCASTGNTSASASAYASRAGMTPVVLLPQGKIAAGKLAQAVVHGGRIIQILGNFDDCLRIARELAENFPVSLVNSIN
PYRIEGQKTAAFEVVDVLGDAPDIHALPVGNAGNITAYWKGYREYVADGPASHTPRMFGFQAAGAAPLVLGHDVNDPETV
ATAIRIGRPASGKLALAARDESEGLIDAVTDEQILDAQTFLAAREGIFVEPASAVGVAGLFKLKSEGRLDPGLRIVVTVT
GNGLKDIDTALSRTTLSTEAVEASTDQVAALLDFCS
>Mature_355_residues
SQQNRLFGVIETYRDRLPMDGIDQIVTLGEGATPLVPAPRLGAELDATVWVKVEGANPTGSFKDRGMTMAMTKALADGSK
AVVCASTGNTSASASAYASRAGMTPVVLLPQGKIAAGKLAQAVVHGGRIIQILGNFDDCLRIARELAENFPVSLVNSINP
YRIEGQKTAAFEVVDVLGDAPDIHALPVGNAGNITAYWKGYREYVADGPASHTPRMFGFQAAGAAPLVLGHDVNDPETVA
TAIRIGRPASGKLALAARDESEGLIDAVTDEQILDAQTFLAAREGIFVEPASAVGVAGLFKLKSEGRLDPGLRIVVTVTG
NGLKDIDTALSRTTLSTEAVEASTDQVAALLDFCS

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322631, Length=282, Percent_Identity=26.9503546099291, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37202; Mature: 37070

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQNRLFGVIETYRDRLPMDGIDQIVTLGEGATPLVPAPRLGAELDATVWVKVEGANPT
CCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GSFKDRGMTMAMTKALADGSKAVVCASTGNTSASASAYASRAGMTPVVLLPQGKIAAGKL
CCHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHH
AQAVVHGGRIIQILGNFDDCLRIARELAENFPVSLVNSINPYRIEGQKTAAFEVVDVLGD
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEHHHCCCCEEECCCCHHHHHHHHHHCC
APDIHALPVGNAGNITAYWKGYREYVADGPASHTPRMFGFQAAGAAPLVLGHDVNDPETV
CCCEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEECCCCCHHHH
ATAIRIGRPASGKLALAARDESEGLIDAVTDEQILDAQTFLAAREGIFVEPASAVGVAGL
HHHHHCCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHCCCEECCHHHHHHHHH
FKLKSEGRLDPGLRIVVTVTGNGLKDIDTALSRTTLSTEAVEASTDQVAALLDFCS
EEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
SQQNRLFGVIETYRDRLPMDGIDQIVTLGEGATPLVPAPRLGAELDATVWVKVEGANPT
CCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GSFKDRGMTMAMTKALADGSKAVVCASTGNTSASASAYASRAGMTPVVLLPQGKIAAGKL
CCHHHCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHH
AQAVVHGGRIIQILGNFDDCLRIARELAENFPVSLVNSINPYRIEGQKTAAFEVVDVLGD
HHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEHHHCCCCEEECCCCHHHHHHHHHHCC
APDIHALPVGNAGNITAYWKGYREYVADGPASHTPRMFGFQAAGAAPLVLGHDVNDPETV
CCCEEEEECCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEECCCCCHHHH
ATAIRIGRPASGKLALAARDESEGLIDAVTDEQILDAQTFLAAREGIFVEPASAVGVAGL
HHHHHCCCCCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHCCCEECCHHHHHHHHH
FKLKSEGRLDPGLRIVVTVTGNGLKDIDTALSRTTLSTEAVEASTDQVAALLDFCS
EEECCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA