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The map label for this gene is 50842715

Identifier: 50842715

GI number: 50842715

Start: 1342891

End: 1343727

Strand: Direct

Name: 50842715

Synonym: PPA1235

Alternate gene names: NA

Gene position: 1342891-1343727 (Clockwise)

Preceding gene: 50842714

Following gene: 50842716

Centisome position: 52.45

GC content: 61.77

Gene sequence:

>837_bases
ATGACACCACTCCCCCATCCACGTATCGCCACCCTGTTCGAGTCACCGGTAGCCCCTGGCAGCGGATGGCCAGGAGATCC
GGCATCACCGGACACCCCCGTCGCCAAATGCGCCGAGGATGCAGCGAGAATCGCTGCACACTGCAGCGAATTTGAGGATC
TCGACGCTACTATTTCGGTATGCCGCGCGTGCCCGCGCCTCGTCAAGTGGCGCGAGGACATAGCGGTCACTAAGCGCGCT
CAATGGCGTGATGAACCTTATTGGGGGCGACCCGTACCGTCATTCGGCGATCCATCCGCTCGCATGGTTATCATCGGCCT
GGCTCCCGCCGCACACGGAGCTAACCGCACAGGACGAATGTTCACCGGTGACCAGTCCGGGGACTGGCTTTACCGCGCTT
TATATGACGCCGACATTGCCTCACAAGCACAGAGCATTGACGCTGCGGATGGTCTCACCCTTCACGACTGTCACATCATC
GCCCCGGTACACTGCGCACCACCAGACAACTGGCCTCGACCCGACGAGAAGCGCACTTGCGCTATCTGGTTTGATGATGA
GCTAGCGCGTTTAACCGCCCTGCGTGCAGTGATGTGCCTAGGGCAGATTGCCTGGACCTCAACCCTGGCAGCCGCCCGTC
GTCTTGGATGGCAGGTCCCGCGCCCTGCACCCCGCTTTGGTCACGGCACCCGCACTCAACTCGTCCGGCCCGACGGGTCC
ATCATCGTCGTACTGGGGTGTTACCACGTCAGTCGTCAGAACACGAACACCGGACGGCTCACTCGCAGCATGCTTGACGA
CGCCGTCAACACGCTCCGGGATCTGGCCACTACCTGA

Upstream 100 bases:

>100_bases
ATGGCAATCCTCGTCGTCACAGCTGTGATGAGCCGACACCACCACATGAAACATTTCGTCCAAGAGCCACTCAACACGAC
CGCATCATCAAGAAGTAGCT

Downstream 100 bases:

>100_bases
GGAATACCTCCATGAGTGCAGGCGCAACACCGTCACCAGATTCGGCAGCTTAATCGATACTCAGGAAAACTGTATCCATC
TCGGCAAGGATGGCGAGACA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTPLPHPRIATLFESPVAPGSGWPGDPASPDTPVAKCAEDAARIAAHCSEFEDLDATISVCRACPRLVKWREDIAVTKRA
QWRDEPYWGRPVPSFGDPSARMVIIGLAPAAHGANRTGRMFTGDQSGDWLYRALYDADIASQAQSIDAADGLTLHDCHII
APVHCAPPDNWPRPDEKRTCAIWFDDELARLTALRAVMCLGQIAWTSTLAAARRLGWQVPRPAPRFGHGTRTQLVRPDGS
IIVVLGCYHVSRQNTNTGRLTRSMLDDAVNTLRDLATT

Sequences:

>Translated_278_residues
MTPLPHPRIATLFESPVAPGSGWPGDPASPDTPVAKCAEDAARIAAHCSEFEDLDATISVCRACPRLVKWREDIAVTKRA
QWRDEPYWGRPVPSFGDPSARMVIIGLAPAAHGANRTGRMFTGDQSGDWLYRALYDADIASQAQSIDAADGLTLHDCHII
APVHCAPPDNWPRPDEKRTCAIWFDDELARLTALRAVMCLGQIAWTSTLAAARRLGWQVPRPAPRFGHGTRTQLVRPDGS
IIVVLGCYHVSRQNTNTGRLTRSMLDDAVNTLRDLATT
>Mature_277_residues
TPLPHPRIATLFESPVAPGSGWPGDPASPDTPVAKCAEDAARIAAHCSEFEDLDATISVCRACPRLVKWREDIAVTKRAQ
WRDEPYWGRPVPSFGDPSARMVIIGLAPAAHGANRTGRMFTGDQSGDWLYRALYDADIASQAQSIDAADGLTLHDCHIIA
PVHCAPPDNWPRPDEKRTCAIWFDDELARLTALRAVMCLGQIAWTSTLAAARRLGWQVPRPAPRFGHGTRTQLVRPDGSI
IVVLGCYHVSRQNTNTGRLTRSMLDDAVNTLRDLATT

Specific function: Unknown

COG id: COG1573

COG function: function code L; Uracil-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1105 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: NA

Molecular weight: Translated: 30437; Mature: 30306

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLPHPRIATLFESPVAPGSGWPGDPASPDTPVAKCAEDAARIAAHCSEFEDLDATISV
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CRACPRLVKWREDIAVTKRAQWRDEPYWGRPVPSFGDPSARMVIIGLAPAAHGANRTGRM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCE
FTGDQSGDWLYRALYDADIASQAQSIDAADGLTLHDCHIIAPVHCAPPDNWPRPDEKRTC
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEEEEECCCCCCCCCCCCCCEE
AIWFDDELARLTALRAVMCLGQIAWTSTLAAARRLGWQVPRPAPRFGHGTRTQLVRPDGS
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCC
IIVVLGCYHVSRQNTNTGRLTRSMLDDAVNTLRDLATT
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPLPHPRIATLFESPVAPGSGWPGDPASPDTPVAKCAEDAARIAAHCSEFEDLDATISV
CCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CRACPRLVKWREDIAVTKRAQWRDEPYWGRPVPSFGDPSARMVIIGLAPAAHGANRTGRM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCE
FTGDQSGDWLYRALYDADIASQAQSIDAADGLTLHDCHIIAPVHCAPPDNWPRPDEKRTC
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECEEEEEEEECCCCCCCCCCCCCCEE
AIWFDDELARLTALRAVMCLGQIAWTSTLAAARRLGWQVPRPAPRFGHGTRTQLVRPDGS
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCC
IIVVLGCYHVSRQNTNTGRLTRSMLDDAVNTLRDLATT
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]