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The map label for this gene is 50842716

Identifier: 50842716

GI number: 50842716

Start: 1343890

End: 1344555

Strand: Direct

Name: 50842716

Synonym: PPA1236

Alternate gene names: NA

Gene position: 1343890-1344555 (Clockwise)

Preceding gene: 50842715

Following gene: 50842738

Centisome position: 52.49

GC content: 55.11

Gene sequence:

>666_bases
ATGGTCATTCTTTCCAAGATCTACACCCGTACCGGCGATCATGGCTCTACGCGCTTGGTCGATAATTCTGTGACAGCAAA
ATCAGATCTCCGCGTTGAGGCTTACGGCCTCATCGATCAGGCCAACGCCAGCATCGGCCTAGCAATTGCTCTCGACACCA
CGACGAAGGTTCTCTCGAGAGAGGTTCGAGAAGCTCTCGGCATCATCCAGAACGAGCTGTTCGACGTCGGAGCAGATCTA
GCCAATCCACTTGTTGCTAACCCAAAATGGGAACCACTGCGAACTGTCCAGGAGAGTGTCGATCGGCTAGAGCGCTGGTG
CGATGAATTCGGCGATCAGTTGCCAACTCTCAGGTCTTTCATTCTTCCTGGTGGCAACCCCGTGGGTGCTCAACTTCATG
TCTGCCGTACTGCTATCCGCACGGCTGAGCGCGCTGCGTGGCGAGCTGCCGAGATCTACGGAACCGAGACATCGAATGAT
CCAGAAACCACACCTGGCGGGGTTAATGAGCTCGCAATCACCTACCTTAATCGCCTTTCCGATTTGCTATTTATCCTGTC
TCGAGCCGCAAATAAAGCTGGCGAAGACTCCTCCGATGAGGTGGTGTGGGTTCCCGGCGGGGAACGCAACCCGAGCACGC
AGATGACCAACGACGGCCAGGAATAA

Upstream 100 bases:

>100_bases
AGGAAAACTGTATCCATCTCGGCAAGGATGGCGAGACAGTGCAAACAATCCCGCCCGCCGTTCGTCTTCCGAGCATTGGC
AACGACCGTAGGCTGGGATC

Downstream 100 bases:

>100_bases
TCACACGAGATGCCCTTCGGTGGCGTACTCCACGCCACCAGGGGGTGCGGCCTCCAGCCACGACATCAGCCCAGTAACAA
CCCGAGGGTCGACAACGATC

Product: cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MVILSKIYTRTGDHGSTRLVDNSVTAKSDLRVEAYGLIDQANASIGLAIALDTTTKVLSREVREALGIIQNELFDVGADL
ANPLVANPKWEPLRTVQESVDRLERWCDEFGDQLPTLRSFILPGGNPVGAQLHVCRTAIRTAERAAWRAAEIYGTETSND
PETTPGGVNELAITYLNRLSDLLFILSRAANKAGEDSSDEVVWVPGGERNPSTQMTNDGQE

Sequences:

>Translated_221_residues
MVILSKIYTRTGDHGSTRLVDNSVTAKSDLRVEAYGLIDQANASIGLAIALDTTTKVLSREVREALGIIQNELFDVGADL
ANPLVANPKWEPLRTVQESVDRLERWCDEFGDQLPTLRSFILPGGNPVGAQLHVCRTAIRTAERAAWRAAEIYGTETSND
PETTPGGVNELAITYLNRLSDLLFILSRAANKAGEDSSDEVVWVPGGERNPSTQMTNDGQE
>Mature_221_residues
MVILSKIYTRTGDHGSTRLVDNSVTAKSDLRVEAYGLIDQANASIGLAIALDTTTKVLSREVREALGIIQNELFDVGADL
ANPLVANPKWEPLRTVQESVDRLERWCDEFGDQLPTLRSFILPGGNPVGAQLHVCRTAIRTAERAAWRAAEIYGTETSND
PETTPGGVNELAITYLNRLSDLLFILSRAANKAGEDSSDEVVWVPGGERNPSTQMTNDGQE

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=205, Percent_Identity=33.1707317073171, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534154, Length=186, Percent_Identity=33.8709677419355, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 24094; Mature: 24094

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILSKIYTRTGDHGSTRLVDNSVTAKSDLRVEAYGLIDQANASIGLAIALDTTTKVLSR
CEEHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEECCHHHCCCCEEEEEEECHHHHHHHH
EVREALGIIQNELFDVGADLANPLVANPKWEPLRTVQESVDRLERWCDEFGDQLPTLRSF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILPGGNPVGAQLHVCRTAIRTAERAAWRAAEIYGTETSNDPETTPGGVNELAITYLNRLS
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DLLFILSRAANKAGEDSSDEVVWVPGGERNPSTQMTNDGQE
HHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVILSKIYTRTGDHGSTRLVDNSVTAKSDLRVEAYGLIDQANASIGLAIALDTTTKVLSR
CEEHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEECCHHHCCCCEEEEEEECHHHHHHHH
EVREALGIIQNELFDVGADLANPLVANPKWEPLRTVQESVDRLERWCDEFGDQLPTLRSF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILPGGNPVGAQLHVCRTAIRTAERAAWRAAEIYGTETSNDPETTPGGVNELAITYLNRLS
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DLLFILSRAANKAGEDSSDEVVWVPGGERNPSTQMTNDGQE
HHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]