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The map label for this gene is rpe [H]

Identifier: 50842679

GI number: 50842679

Start: 1306372

End: 1307043

Strand: Direct

Name: rpe [H]

Synonym: PPA1199

Alternate gene names: 50842679

Gene position: 1306372-1307043 (Clockwise)

Preceding gene: 50842678

Following gene: 50842681

Centisome position: 51.02

GC content: 58.63

Gene sequence:

>672_bases
ATGGTAGTTCGCATCACACCGTCAATCCTCAACGCCAACCTCGCCAATCTCGCCAGTGAGGTAGGACGCATCCCCTCAGC
TGACGGTTTACACATCGACGTCATGGATGGCCATTTCGTGCCGAATCTCGTCATGGGGGCGCCCTTCGTGGAATCGTTGC
GACCAGCCACTAACCTCATGTTTGACGTTCACCTCATGATCGAAAATCCCGATTGGTGGGCACGGCAGTACGTCGAGGCG
GGAGCGCAATCGGTCACCTTCCACCTGGAAGCTGCTACCGCGCCAATCAAACTCGCTCGTGAGCTTCGGTCGATGGGAGC
ACGGGCGTCGGTAGCTCTGCGCCCGGCAACCCCAGTCGAACAGCTCGCCGACATCCTGACTGAATTTGACCAAATCCTCC
TCATGACAGTCGAGCCTGGTTTTGGTGGCCAGAAATTCCTCGACCCAGTGCTTGCCAAGATCCGCAAGGCTCGCAAGCTC
ATTGACGCGACACGTAAGGATATCTGGTTGCAAATTGACGGCGGCGTCTCAGCTGACACCATCGAACGCGCTGCCGAAGC
AGGAGCCGACACATTCGTGGCAGGATCCGCCGTGTACCGTTCCGACAACCCCGACCACGTCGTCGCTTCACTGCGCAACC
GGGCTTTGGCTGCGCAGGTATGTGCCCACTGA

Upstream 100 bases:

>100_bases
CTAGTTCAGTCTTAGCCAACACATTCCGAGGCTCCCCTCCAAACTTTTCAGCATGTCAGCGGCATCCATCCGAGTCTGCC
CGATCCCTTAGGCTGGCACC

Downstream 100 bases:

>100_bases
CAGTCCGCGCACAGTGTTAATGACCGCGATGGCGTAGATAGGACTGGAACTCTACCGCGAGGACATCTCCTGTCAGTCCC
TCCGAGAGCGCAGCATCCTG

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MVVRITPSILNANLANLASEVGRIPSADGLHIDVMDGHFVPNLVMGAPFVESLRPATNLMFDVHLMIENPDWWARQYVEA
GAQSVTFHLEAATAPIKLARELRSMGARASVALRPATPVEQLADILTEFDQILLMTVEPGFGGQKFLDPVLAKIRKARKL
IDATRKDIWLQIDGGVSADTIERAAEAGADTFVAGSAVYRSDNPDHVVASLRNRALAAQVCAH

Sequences:

>Translated_223_residues
MVVRITPSILNANLANLASEVGRIPSADGLHIDVMDGHFVPNLVMGAPFVESLRPATNLMFDVHLMIENPDWWARQYVEA
GAQSVTFHLEAATAPIKLARELRSMGARASVALRPATPVEQLADILTEFDQILLMTVEPGFGGQKFLDPVLAKIRKARKL
IDATRKDIWLQIDGGVSADTIERAAEAGADTFVAGSAVYRSDNPDHVVASLRNRALAAQVCAH
>Mature_223_residues
MVVRITPSILNANLANLASEVGRIPSADGLHIDVMDGHFVPNLVMGAPFVESLRPATNLMFDVHLMIENPDWWARQYVEA
GAQSVTFHLEAATAPIKLARELRSMGARASVALRPATPVEQLADILTEFDQILLMTVEPGFGGQKFLDPVLAKIRKARKL
IDATRKDIWLQIDGGVSADTIERAAEAGADTFVAGSAVYRSDNPDHVVASLRNRALAAQVCAH

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=215, Percent_Identity=45.1162790697674, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI219879828, Length=215, Percent_Identity=43.2558139534884, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=36.6863905325444, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1789788, Length=215, Percent_Identity=40.9302325581395, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=33.502538071066, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790754, Length=201, Percent_Identity=29.3532338308458, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=221, Percent_Identity=41.6289592760181, Blast_Score=179, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6322341, Length=225, Percent_Identity=40.4444444444444, Blast_Score=180, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24586301, Length=213, Percent_Identity=39.906103286385, Blast_Score=167, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24158; Mature: 24158

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRITPSILNANLANLASEVGRIPSADGLHIDVMDGHFVPNLVMGAPFVESLRPATNLM
CEEEECHHHHHCHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCHHHHHCHHHHEE
FDVHLMIENPDWWARQYVEAGAQSVTFHLEAATAPIKLARELRSMGARASVALRPATPVE
EEEEEEEECCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCHH
QLADILTEFDQILLMTVEPGFGGQKFLDPVLAKIRKARKLIDATRKDIWLQIDGGVSADT
HHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHH
IERAAEAGADTFVAGSAVYRSDNPDHVVASLRNRALAAQVCAH
HHHHHHCCCCCEEECCEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVRITPSILNANLANLASEVGRIPSADGLHIDVMDGHFVPNLVMGAPFVESLRPATNLM
CEEEECHHHHHCHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCHHHHHCHHHHEE
FDVHLMIENPDWWARQYVEAGAQSVTFHLEAATAPIKLARELRSMGARASVALRPATPVE
EEEEEEEECCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCHH
QLADILTEFDQILLMTVEPGFGGQKFLDPVLAKIRKARKLIDATRKDIWLQIDGGVSADT
HHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHH
IERAAEAGADTFVAGSAVYRSDNPDHVVASLRNRALAAQVCAH
HHHHHHCCCCCEEECCEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]