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The map label for this gene is sun [C]

Identifier: 50842676

GI number: 50842676

Start: 1302779

End: 1304155

Strand: Direct

Name: sun [C]

Synonym: PPA1196

Alternate gene names: 50842676

Gene position: 1302779-1304155 (Clockwise)

Preceding gene: 50842675

Following gene: 50842677

Centisome position: 50.88

GC content: 60.64

Gene sequence:

>1377_bases
ATGACTCAGCGTGTGCATCAGAAACGTCGTAAGGCTGACCCAGCGCGACGACTGGCCTATTCCGCTCTCTTAGCGGTGGA
GACCCACGGCGCCTATGCCAACCTAGCCCTGGCAGATCACTTGCGTGCTGCCAAGTTGACTGGGCGCGATGCGGCATTTG
CCACTGAACTGGTGGATGGAACTTCCCGTGGGACGGGCACTTGGGATCGCATTATTGAGGCCGCCTCCTGCCGGGCTCCC
GCCAAACTCCAGCCGGGAGTCCGGGTGGTGTTGCGCATGGCGGCACATCAGATCCTGGCTATGAGGGTGCCGACGAGGGC
AGCCGTGGCGTCATCGGTTGATCTTGCTGGTCAGGTCATTGGGGAGCGCGTCACTGGCCTTGTCAACGCGATATCGCGTC
GTATCAGTACCCACAGCCTTGAGGAGTGGGCTACCGAGATCGGCGGACGCGATGCCGTTGACGTCATGGCGTTGCGTACC
CTTCATCCCACCTGGATCGTTAAAGCCTTTCAGGACCGTCTGGGTGCAGACGAGGTGGAAGACGCCTTGCTAGCCGATAA
CGAGCCGCCGGTCCCCACCTTGGTTGTTCGTCCCGGGCTCGCTCAGCGCGACGAACTTGGGTCCGGGACCCCGACTCGAT
ATTCCCCGTGGGGAGTTGTGCGTCCCGGAAACCCCTCTGATGTCGCTGCGGTGCGTGAAGGCCGAGCTGGCATACAAGAC
GAGGGTTCCCAACTCGTCATCCTGGCCTTGGTACGCGCGGCCAAGGCAAACAGCTGCTTTGGCCAGTGGCTCGACCTGTG
TGCCGGCCCTGGCGGCAAATCCGCACTGCTAGCTGGACTCGCGAACCAGCACGACACCAGCTTGACCGCAGTGGAACTGC
ACGAGCATCGTGCTGATCTCGTTTCGAAAGCCCTCAGGACCATCCCGGGCGACCATCGCGTTATGACTGCCGACGGCACG
CACCCGCCACTACCGAAACAGTCTTTTGCCGCCGTTCTTGCTGACGTTCCGTGCTCCGGTCTGGGGTCGCTACGCCGACG
CCCAGAAGCTCGGTGGCGTCGTACCCCAACTGACGTCGAAGAGTTAACCCAGCTCCAGCGTCGACTTCTTATCTCAGCGG
TCAATCTCACCCGACCAGGTGGGGTCATTGGGTACGTCACGTGTTCACCGCATCGAGCCGAAACCATCGATATCATCAAT
TCTGCATGCGCGACCCTACCTGTCGATGTCCTCGACGCTCCTGCCATGCTCCCTAACATTCCTAATATTGCTGCGTCTGG
AAACACCAACACCATCCAGCTGTGGCCACACCGTCACGGCACCGATGCCATGTTCTGTGCACTGTTACGCAAACGCGACG
AGTCAGGTACATATTGA

Upstream 100 bases:

>100_bases
AGCCCCTCGAGCTGCTGCAGGTGCAAGCTTTCGGTAAGAGAGCTATGAGTGGGGCTGACTGGGCCCGAGGGGCCGACATC
GACGCTGGAACTAGGCTGAG

Downstream 100 bases:

>100_bases
GCAATGAGAGTTCGCACCTCATCTGGCGTCCATGATCGCCATCCGTGGTAAAATTACCCTGACTGCGAGCGCGGGCGCTC
AAGCTACCCGTTGCGAATAT

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTQRVHQKRRKADPARRLAYSALLAVETHGAYANLALADHLRAAKLTGRDAAFATELVDGTSRGTGTWDRIIEAASCRAP
AKLQPGVRVVLRMAAHQILAMRVPTRAAVASSVDLAGQVIGERVTGLVNAISRRISTHSLEEWATEIGGRDAVDVMALRT
LHPTWIVKAFQDRLGADEVEDALLADNEPPVPTLVVRPGLAQRDELGSGTPTRYSPWGVVRPGNPSDVAAVREGRAGIQD
EGSQLVILALVRAAKANSCFGQWLDLCAGPGGKSALLAGLANQHDTSLTAVELHEHRADLVSKALRTIPGDHRVMTADGT
HPPLPKQSFAAVLADVPCSGLGSLRRRPEARWRRTPTDVEELTQLQRRLLISAVNLTRPGGVIGYVTCSPHRAETIDIIN
SACATLPVDVLDAPAMLPNIPNIAASGNTNTIQLWPHRHGTDAMFCALLRKRDESGTY

Sequences:

>Translated_458_residues
MTQRVHQKRRKADPARRLAYSALLAVETHGAYANLALADHLRAAKLTGRDAAFATELVDGTSRGTGTWDRIIEAASCRAP
AKLQPGVRVVLRMAAHQILAMRVPTRAAVASSVDLAGQVIGERVTGLVNAISRRISTHSLEEWATEIGGRDAVDVMALRT
LHPTWIVKAFQDRLGADEVEDALLADNEPPVPTLVVRPGLAQRDELGSGTPTRYSPWGVVRPGNPSDVAAVREGRAGIQD
EGSQLVILALVRAAKANSCFGQWLDLCAGPGGKSALLAGLANQHDTSLTAVELHEHRADLVSKALRTIPGDHRVMTADGT
HPPLPKQSFAAVLADVPCSGLGSLRRRPEARWRRTPTDVEELTQLQRRLLISAVNLTRPGGVIGYVTCSPHRAETIDIIN
SACATLPVDVLDAPAMLPNIPNIAASGNTNTIQLWPHRHGTDAMFCALLRKRDESGTY
>Mature_457_residues
TQRVHQKRRKADPARRLAYSALLAVETHGAYANLALADHLRAAKLTGRDAAFATELVDGTSRGTGTWDRIIEAASCRAPA
KLQPGVRVVLRMAAHQILAMRVPTRAAVASSVDLAGQVIGERVTGLVNAISRRISTHSLEEWATEIGGRDAVDVMALRTL
HPTWIVKAFQDRLGADEVEDALLADNEPPVPTLVVRPGLAQRDELGSGTPTRYSPWGVVRPGNPSDVAAVREGRAGIQDE
GSQLVILALVRAAKANSCFGQWLDLCAGPGGKSALLAGLANQHDTSLTAVELHEHRADLVSKALRTIPGDHRVMTADGTH
PPLPKQSFAAVLADVPCSGLGSLRRRPEARWRRTPTDVEELTQLQRRLLISAVNLTRPGGVIGYVTCSPHRAETIDIINS
ACATLPVDVLDAPAMLPNIPNIAASGNTNTIQLWPHRHGTDAMFCALLRKRDESGTY

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=179, Percent_Identity=29.608938547486, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI76150625, Length=262, Percent_Identity=25.5725190839695, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI76150623, Length=262, Percent_Identity=25.5725190839695, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI2367212, Length=358, Percent_Identity=29.608938547486, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081985, Length=233, Percent_Identity=29.1845493562232, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI22024126, Length=243, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49196; Mature: 49065

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRVHQKRRKADPARRLAYSALLAVETHGAYANLALADHLRAAKLTGRDAAFATELVDG
CCHHHHHHHHCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
TSRGTGTWDRIIEAASCRAPAKLQPGVRVVLRMAAHQILAMRVPTRAAVASSVDLAGQVI
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GERVTGLVNAISRRISTHSLEEWATEIGGRDAVDVMALRTLHPTWIVKAFQDRLGADEVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHH
DALLADNEPPVPTLVVRPGLAQRDELGSGTPTRYSPWGVVRPGNPSDVAAVREGRAGIQD
HHHHCCCCCCCCEEEECCCCCCHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCC
EGSQLVILALVRAAKANSCFGQWLDLCAGPGGKSALLAGLANQHDTSLTAVELHEHRADL
CCCCEEHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHH
VSKALRTIPGDHRVMTADGTHPPLPKQSFAAVLADVPCSGLGSLRRRPEARWRRTPTDVE
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCHHHHCCCCCCHH
ELTQLQRRLLISAVNLTRPGGVIGYVTCSPHRAETIDIINSACATLPVDVLDAPAMLPNI
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHCCCHHCCCC
PNIAASGNTNTIQLWPHRHGTDAMFCALLRKRDESGTY
CCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQRVHQKRRKADPARRLAYSALLAVETHGAYANLALADHLRAAKLTGRDAAFATELVDG
CHHHHHHHHCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
TSRGTGTWDRIIEAASCRAPAKLQPGVRVVLRMAAHQILAMRVPTRAAVASSVDLAGQVI
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GERVTGLVNAISRRISTHSLEEWATEIGGRDAVDVMALRTLHPTWIVKAFQDRLGADEVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCHHHHH
DALLADNEPPVPTLVVRPGLAQRDELGSGTPTRYSPWGVVRPGNPSDVAAVREGRAGIQD
HHHHCCCCCCCCEEEECCCCCCHHCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCC
EGSQLVILALVRAAKANSCFGQWLDLCAGPGGKSALLAGLANQHDTSLTAVELHEHRADL
CCCCEEHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHH
VSKALRTIPGDHRVMTADGTHPPLPKQSFAAVLADVPCSGLGSLRRRPEARWRRTPTDVE
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCHHHHCCCCCCHH
ELTQLQRRLLISAVNLTRPGGVIGYVTCSPHRAETIDIINSACATLPVDVLDAPAMLPNI
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHCCCHHCCCC
PNIAASGNTNTIQLWPHRHGTDAMFCALLRKRDESGTY
CCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]