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The map label for this gene is ruvC

Identifier: 50842638

GI number: 50842638

Start: 1259071

End: 1259661

Strand: Direct

Name: ruvC

Synonym: PPA1158

Alternate gene names: 50842638

Gene position: 1259071-1259661 (Clockwise)

Preceding gene: 50842637

Following gene: 50842639

Centisome position: 49.18

GC content: 62.27

Gene sequence:

>591_bases
GTGAGCATTCCAAAGTCGACCCCCGACCGGCGTGTTACAAGGGTCATGGGGGTCGACCCTGGTTTAACCCGGTGCGGGGT
TGGCGTCGTTGAAGGTGGGTTAGGATCCTCCCTGAAGCTCATTGCCGTGGGCGTCATTCGTACTCCTGCCGACCTCGATC
ATGCACACCGACTACTGCGCATCCACGACGGGCTGGAGGAGTGGCGTGACCACACCCGCCCCGATGCCATTGCCGTCGAG
AAAGTGTTTGCCCAGCACAACCGCAATACGGTAGCTGGTACCGCTCAGGCAGCCGGAATCGCGATGATGATTGCCGCCCG
GCATGGTCTTCCAGTTGCTCTTCACACTCCAAGTGAGGTTAAAGCGGCAATCTCGGGTTCAGGACGAGCCGACAAAGCCC
AGGTGGGTTTCATGGTGGCACGGGTGTTGCGGCTCTCGGCTCCTCCCAAGCCTGCTGATGCTGCCGACGCTGTCGCCTTG
GCGATCTGCCACCTGTGGCGTGGCGGGGCGGCTCGTCGCATTGAAGCTGCTGTGGCTACGCAACGACGCGGTCGGCGTGT
GCCCCGTTCTTGGAAGGACCTAGCCCGGTGA

Upstream 100 bases:

>100_bases
ACAGGATCCTTGATGCTCTCGAAGATCTCGACGACGTCCAGAACGTGTTCTCCAACGTTGATATCCCCGCCGAGGTTGCA
GCAGCTCTTGACGAGGAGGA

Downstream 100 bases:

>100_bases
TTTCCCATTTTTCCGGCACGGTAAGTGCTGCCGGCCCGACTTGGGTCGTCCTTGACAATCATGGGGTCGGTATCAAGGTG
CTATGCCCTCCTGCCACAGC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSIPKSTPDRRVTRVMGVDPGLTRCGVGVVEGGLGSSLKLIAVGVIRTPADLDHAHRLLRIHDGLEEWRDHTRPDAIAVE
KVFAQHNRNTVAGTAQAAGIAMMIAARHGLPVALHTPSEVKAAISGSGRADKAQVGFMVARVLRLSAPPKPADAADAVAL
AICHLWRGGAARRIEAAVATQRRGRRVPRSWKDLAR

Sequences:

>Translated_196_residues
MSIPKSTPDRRVTRVMGVDPGLTRCGVGVVEGGLGSSLKLIAVGVIRTPADLDHAHRLLRIHDGLEEWRDHTRPDAIAVE
KVFAQHNRNTVAGTAQAAGIAMMIAARHGLPVALHTPSEVKAAISGSGRADKAQVGFMVARVLRLSAPPKPADAADAVAL
AICHLWRGGAARRIEAAVATQRRGRRVPRSWKDLAR
>Mature_195_residues
SIPKSTPDRRVTRVMGVDPGLTRCGVGVVEGGLGSSLKLIAVGVIRTPADLDHAHRLLRIHDGLEEWRDHTRPDAIAVEK
VFAQHNRNTVAGTAQAAGIAMMIAARHGLPVALHTPSEVKAAISGSGRADKAQVGFMVARVLRLSAPPKPADAADAVALA
ICHLWRGGAARRIEAAVATQRRGRRVPRSWKDLAR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=136, Percent_Identity=36.0294117647059, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_PROAC (Q6A8K9)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055865.1
- ProteinModelPortal:   Q6A8K9
- SMR:   Q6A8K9
- GeneID:   2931418
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1158
- NMPDR:   fig|267747.1.peg.1142
- HOGENOM:   HBG437552
- OMA:   DCAAIEK
- ProtClustDB:   PRK00039
- BioCyc:   PACN267747:PPA1158-MONOMER
- BRENDA:   3.1.22.4
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 20877; Mature: 20746

Theoretical pI: Translated: 11.78; Mature: 11.78

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPKSTPDRRVTRVMGVDPGLTRCGVGVVEGGLGSSLKLIAVGVIRTPADLDHAHRLLR
CCCCCCCCHHHHHHHHCCCCCHHHHCHHHHCCCCCCCEEEEEEEHHCCCCCHHHHHHHHH
IHDGLEEWRDHTRPDAIAVEKVFAQHNRNTVAGTAQAAGIAMMIAARHGLPVALHTPSEV
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHH
KAAISGSGRADKAQVGFMVARVLRLSAPPKPADAADAVALAICHLWRGGAARRIEAAVAT
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
QRRGRRVPRSWKDLAR
HHHCCCCCCHHHHHCC
>Mature Secondary Structure 
SIPKSTPDRRVTRVMGVDPGLTRCGVGVVEGGLGSSLKLIAVGVIRTPADLDHAHRLLR
CCCCCCCHHHHHHHHCCCCCHHHHCHHHHCCCCCCCEEEEEEEHHCCCCCHHHHHHHHH
IHDGLEEWRDHTRPDAIAVEKVFAQHNRNTVAGTAQAAGIAMMIAARHGLPVALHTPSEV
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECHHHH
KAAISGSGRADKAQVGFMVARVLRLSAPPKPADAADAVALAICHLWRGGAARRIEAAVAT
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
QRRGRRVPRSWKDLAR
HHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA