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The map label for this gene is ybbF [H]

Identifier: 50842621

GI number: 50842621

Start: 1241275

End: 1242834

Strand: Direct

Name: ybbF [H]

Synonym: PPA1142

Alternate gene names: 50842621

Gene position: 1241275-1242834 (Clockwise)

Preceding gene: 50842620

Following gene: 50842622

Centisome position: 48.48

GC content: 55.64

Gene sequence:

>1560_bases
ATGAGAACCACCTTCGCCTGTGAATCTTCCAGGGAGGAAGTCATGGACTATCACTTGCTTGCACGAGAAATACTCGATCT
TGTTGGAGGGCCCGACAATATCGAGTCTTTTACCAATTGCATGACGCGGCTGCGTCTCAACCTCATCCGGCCCCAGACTG
CTGATGCTGAGGCCATCAATGGGCTGGCTGGGGTCCTTGGAGTCGTCGAGGGTAAGCAGCTGCAAGTCGTCGTCGGGCCT
GGTCACGCGGAAAGATTACGGTCAGCATTCGGTGAGGTCATGGGGTCGGCGGATTCTGCTTCTGCCACCGACACAGACGC
GACGACTCAAGTCACGCCGCCTGGCACCGCAAAGCGAGGTGTGGACTCTGCAGTGGTCGAGACAGAGCCGAGTCCAGTCC
TGGAAGGTGATACAGATATAGCCGTTCGGACCAAGAAGATGGTCCGAGGCACGCAAACATCTAGGGTGCAAGCGATGTTC
CGTCACGTCGGGAACATTTTCGTCCCGATCATTCCAGGGTTCATCGCCTGTGGGCTAGTGACCGCAATCTGCGGGATTTG
GAAGACAATTGACCCCACGGTTGCCAATGACGGGTGGTTCCTGGTTTTAGTTGGTCTGGGAGGGATCGTTATTGCCTCGC
TCAACTTCATCGTCGGCCACAACACAGCTCAAGAATGTGGTGGCAGCCCGGTGCTAGGCCTCATCGCGGGCGGGGTTCCA
TATATGCCCGCTCTGGCGGGTACGGCAGCAACCGACAAGACGGCAGCTATCCCGCTGACGATCCCAATATTCGGGGAGCT
TCAACCCGGACTGGGAGGTGTCATCGGCGTCATGATCACCGCCTGGCTGTTCACCGTCATCGAAAGGCGGTTGAGAAAGG
TTATCCCGGCGGCTATGGAACTTTTTCTTGTGCCGGTTGTAACTTTGCTCCTCGGCGCCGCAGCGTCAATCTTTGTGATC
ATGCCGTTGTCATCCTTGCTGATGAAGGGCCTCACATGGCTGCTCGTTGACTTCGCCCTTGCTAAAGGTGGAATCATCGG
CGGATTTATCCTCGCAACCTTCTTCTTGCCTATGGTGATGTTGGGCATTCATCAGGGACTGACCCCAATTCATGCTCAAC
TCATCGCCAATCATGGTTTTACCGAACTATTACCCATTCTTGCGATGGCTGGTGCGGCTCAGGTGGGAATGGCCATTGCC
GTTCTTATGAAAACCAGGAATCCGAAACTGCGGTCTGTGATTAAGAGCGCGCTACCAATTGGCATCCTTGGTGTGGGCGA
ACCCCTCATTTACGGGGTCTCGTTACCGTTGCTATACCCCTTCCTCACCGCGTGTCTTGGTGGTGGCTTCGGAGGTGCCT
TTATAGCGTGGGGGATGCAGAACTCCGGAACGTTTGGCTCCCAGGCCTTTGGCCTGTCGGGCTTACTCATGGCACCGGTG
ATTTCGGCCGGCAAGTGGGGCTGGTATCTCGGTGGCTGGCTTATTTCAGTAATCATGGGAGCTGTGCTCACTTACCTGTT
CGGTTTCAAGGATTCCATGGCCGAACGCATTATGGACTGA

Upstream 100 bases:

>100_bases
CATGCCAAGACGGCCATTGTCATGGTGCTGTTGGGGATGACTGCGACTCAAGCTCGAGCCCGACTGGCTGAAGTGGGCGG
CGTAGTCCGGGTAGCCGTCG

Downstream 100 bases:

>100_bases
TCGATGATGCGGTCCGTATATCTGACCAACGAGAGTTGTGGCCTCGTTGCTCGCCAGGCTGCTTCGCACAGCAAGGTCAT
ATTCGCCTCGCTACAGATGC

Product: PTS system, sucrose-specific IIBC component

Products: NA

Alternate protein names: Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MRTTFACESSREEVMDYHLLAREILDLVGGPDNIESFTNCMTRLRLNLIRPQTADAEAINGLAGVLGVVEGKQLQVVVGP
GHAERLRSAFGEVMGSADSASATDTDATTQVTPPGTAKRGVDSAVVETEPSPVLEGDTDIAVRTKKMVRGTQTSRVQAMF
RHVGNIFVPIIPGFIACGLVTAICGIWKTIDPTVANDGWFLVLVGLGGIVIASLNFIVGHNTAQECGGSPVLGLIAGGVP
YMPALAGTAATDKTAAIPLTIPIFGELQPGLGGVIGVMITAWLFTVIERRLRKVIPAAMELFLVPVVTLLLGAAASIFVI
MPLSSLLMKGLTWLLVDFALAKGGIIGGFILATFFLPMVMLGIHQGLTPIHAQLIANHGFTELLPILAMAGAAQVGMAIA
VLMKTRNPKLRSVIKSALPIGILGVGEPLIYGVSLPLLYPFLTACLGGGFGGAFIAWGMQNSGTFGSQAFGLSGLLMAPV
ISAGKWGWYLGGWLISVIMGAVLTYLFGFKDSMAERIMD

Sequences:

>Translated_519_residues
MRTTFACESSREEVMDYHLLAREILDLVGGPDNIESFTNCMTRLRLNLIRPQTADAEAINGLAGVLGVVEGKQLQVVVGP
GHAERLRSAFGEVMGSADSASATDTDATTQVTPPGTAKRGVDSAVVETEPSPVLEGDTDIAVRTKKMVRGTQTSRVQAMF
RHVGNIFVPIIPGFIACGLVTAICGIWKTIDPTVANDGWFLVLVGLGGIVIASLNFIVGHNTAQECGGSPVLGLIAGGVP
YMPALAGTAATDKTAAIPLTIPIFGELQPGLGGVIGVMITAWLFTVIERRLRKVIPAAMELFLVPVVTLLLGAAASIFVI
MPLSSLLMKGLTWLLVDFALAKGGIIGGFILATFFLPMVMLGIHQGLTPIHAQLIANHGFTELLPILAMAGAAQVGMAIA
VLMKTRNPKLRSVIKSALPIGILGVGEPLIYGVSLPLLYPFLTACLGGGFGGAFIAWGMQNSGTFGSQAFGLSGLLMAPV
ISAGKWGWYLGGWLISVIMGAVLTYLFGFKDSMAERIMD
>Mature_519_residues
MRTTFACESSREEVMDYHLLAREILDLVGGPDNIESFTNCMTRLRLNLIRPQTADAEAINGLAGVLGVVEGKQLQVVVGP
GHAERLRSAFGEVMGSADSASATDTDATTQVTPPGTAKRGVDSAVVETEPSPVLEGDTDIAVRTKKMVRGTQTSRVQAMF
RHVGNIFVPIIPGFIACGLVTAICGIWKTIDPTVANDGWFLVLVGLGGIVIASLNFIVGHNTAQECGGSPVLGLIAGGVP
YMPALAGTAATDKTAAIPLTIPIFGELQPGLGGVIGVMITAWLFTVIERRLRKVIPAAMELFLVPVVTLLLGAAASIFVI
MPLSSLLMKGLTWLLVDFALAKGGIIGGFILATFFLPMVMLGIHQGLTPIHAQLIANHGFTELLPILAMAGAAQVGMAIA
VLMKTRNPKLRSVIKSALPIGILGVGEPLIYGVSLPLLYPFLTACLGGGFGGAFIAWGMQNSGTFGSQAFGLSGLLMAPV
ISAGKWGWYLGGWLISVIMGAVLTYLFGFKDSMAERIMD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788769, Length=512, Percent_Identity=35.7421875, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1790159, Length=455, Percent_Identity=28.7912087912088, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI2367362, Length=443, Percent_Identity=24.1534988713318, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI48994906, Length=254, Percent_Identity=27.1653543307087, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 54455; Mature: 54455

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTFACESSREEVMDYHLLAREILDLVGGPDNIESFTNCMTRLRLNLIRPQTADAEAIN
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
GLAGVLGVVEGKQLQVVVGPGHAERLRSAFGEVMGSADSASATDTDATTQVTPPGTAKRG
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHCC
VDSAVVETEPSPVLEGDTDIAVRTKKMVRGTQTSRVQAMFRHVGNIFVPIIPGFIACGLV
CCCHHEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TAICGIWKTIDPTVANDGWFLVLVGLGGIVIASLNFIVGHNTAQECGGSPVLGLIAGGVP
HHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHCCCC
YMPALAGTAATDKTAAIPLTIPIFGELQPGLGGVIGVMITAWLFTVIERRLRKVIPAAME
HHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLVPVVTLLLGAAASIFVIMPLSSLLMKGLTWLLVDFALAKGGIIGGFILATFFLPMVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGIHQGLTPIHAQLIANHGFTELLPILAMAGAAQVGMAIAVLMKTRNPKLRSVIKSALPI
HHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
GILGVGEPLIYGVSLPLLYPFLTACLGGGFGGAFIAWGMQNSGTFGSQAFGLSGLLMAPV
EEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCCHHHCCCHHHHHHH
ISAGKWGWYLGGWLISVIMGAVLTYLFGFKDSMAERIMD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTTFACESSREEVMDYHLLAREILDLVGGPDNIESFTNCMTRLRLNLIRPQTADAEAIN
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
GLAGVLGVVEGKQLQVVVGPGHAERLRSAFGEVMGSADSASATDTDATTQVTPPGTAKRG
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHCC
VDSAVVETEPSPVLEGDTDIAVRTKKMVRGTQTSRVQAMFRHVGNIFVPIIPGFIACGLV
CCCHHEECCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
TAICGIWKTIDPTVANDGWFLVLVGLGGIVIASLNFIVGHNTAQECGGSPVLGLIAGGVP
HHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHCCCC
YMPALAGTAATDKTAAIPLTIPIFGELQPGLGGVIGVMITAWLFTVIERRLRKVIPAAME
HHHHHCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLVPVVTLLLGAAASIFVIMPLSSLLMKGLTWLLVDFALAKGGIIGGFILATFFLPMVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGIHQGLTPIHAQLIANHGFTELLPILAMAGAAQVGMAIAVLMKTRNPKLRSVIKSALPI
HHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
GILGVGEPLIYGVSLPLLYPFLTACLGGGFGGAFIAWGMQNSGTFGSQAFGLSGLLMAPV
EEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCCHHHCCCHHHHHHH
ISAGKWGWYLGGWLISVIMGAVLTYLFGFKDSMAERIMD
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]