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The map label for this gene is trpB [H]

Identifier: 50842610

GI number: 50842610

Start: 1227369

End: 1228625

Strand: Direct

Name: trpB [H]

Synonym: PPA1131

Alternate gene names: 50842610

Gene position: 1227369-1228625 (Clockwise)

Preceding gene: 50842609

Following gene: 50842611

Centisome position: 47.94

GC content: 60.94

Gene sequence:

>1257_bases
ATGTCCGCACGAGACTTGCCCGACGCTCGGGGACACTTCGACCGTTTCGGTGGCCGATTCGTTCCAGAAGCTCTCCAAGC
TGCTCTTAGCCAGCTTACGGGGACCTTCGAGGCCGCGGTAACCGATCCTGACTTTCTCACTGAGCTGGAGGATCTGCGCC
GGGAGTACGCCGGACGCCCCTCTCCGCTTACAGAGGCACCGCGATTTTCTCAATACATCTTTCAACAGACCGGTCATCAG
GTGCGAGTCCTTCTGAAGCGCGAGGACCTGAACCACACCGGTTCTCACAAGATCAACAATGTGTTGGGCCAAGCCCTGCT
GACTCGAAAGATGGGCAAGCGCCGTCTCATTGCGGAGACGGGAGCTGGACAGCATGGCGTGGCGACGGCAACCGTGGCCG
CGATGATGGGCATGGAGTGCCGGATCTATATGGGCCAGATCGACACTGAGCGTCAGGCCCTCAATGTGGCTCGCATGCAG
CTGTTGGGCGCCGAGGTCATTGCAGTGGAAGCCGGCTCGCGCACGTTGAAGGACGCCATGAACGAGGCCATGCGAGATTG
GGTGGCCCATGTTGAGGACACCCACTACCTCATCGGTACCGCTTCTGGGCCACACCCGTTCCCTAAACTGGTGCGAGAGT
TTCAGCGGGTCATTTCTGCGGAGGCCCGTCAGCAGTGCCTTGATCGGGTTGGACGCCTTCCCGACGCCATTTGTGCGTGT
GTCGGTGGTGGGTCGAATGCCATCGGATCGTTCGCCGAGTTCATCGACGACCCCGAGGTTCGTCTCTACGGTTTCGAGGC
GGGCGGTGACGGTGTCGAGACCGGTCGCCATGCAGCATCGATCACCAGGGGTTCCGTTGGTGTACTGCACGGCACTCGCA
CCTACATTCTGCAAGATCCGGACGGCCAGACGATGGAATCTCACTCCATATCGGCCGGCCTGGACTATCCCGGAGTTGGC
CCCGAACATTCTTGGTTAGCGGCCCGGAAGCGTGCTACTTACCTCCCGGTCAACGACCGCGAGGCCATGGAGGCTCTACG
TACCCTCACCCGCACCGAAGGCATCATGCCGGCCATTGAGTCGGCCCACGCTGTCGCCGGCGTTCTTAAGATCGCGAAAG
ACCTGCCTGCTCACGACGGCGAGCCGTCAGTGGTCATCGTCACGGTGTCGGGTCGCGGGGATAAAGATGTTGACACTGCC
CTGGAGTGGTTTGCCATGGACGGCAGCGTCGACGCCACTACGGGAGGTATGGAATGA

Upstream 100 bases:

>100_bases
GGTGGGGGAGATGCTGGTCCGCCACGGTGAACCAGCACAAGTATTGCGCAAGATCCACCGTGCCACCGTGTGACCCTGAC
ATTCAATGGAAAGGACGATC

Downstream 100 bases:

>100_bases
CCGGTAGCGCCAGTGTCTACCTCAGGGCCCACCAAGAGAACCGCCCGGCCCTCGTCGGTTACTTCCCGGTGGGACACCCG
TCAGTTCCTCACTCGATCGA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSARDLPDARGHFDRFGGRFVPEALQAALSQLTGTFEAAVTDPDFLTELEDLRREYAGRPSPLTEAPRFSQYIFQQTGHQ
VRVLLKREDLNHTGSHKINNVLGQALLTRKMGKRRLIAETGAGQHGVATATVAAMMGMECRIYMGQIDTERQALNVARMQ
LLGAEVIAVEAGSRTLKDAMNEAMRDWVAHVEDTHYLIGTASGPHPFPKLVREFQRVISAEARQQCLDRVGRLPDAICAC
VGGGSNAIGSFAEFIDDPEVRLYGFEAGGDGVETGRHAASITRGSVGVLHGTRTYILQDPDGQTMESHSISAGLDYPGVG
PEHSWLAARKRATYLPVNDREAMEALRTLTRTEGIMPAIESAHAVAGVLKIAKDLPAHDGEPSVVIVTVSGRGDKDVDTA
LEWFAMDGSVDATTGGME

Sequences:

>Translated_418_residues
MSARDLPDARGHFDRFGGRFVPEALQAALSQLTGTFEAAVTDPDFLTELEDLRREYAGRPSPLTEAPRFSQYIFQQTGHQ
VRVLLKREDLNHTGSHKINNVLGQALLTRKMGKRRLIAETGAGQHGVATATVAAMMGMECRIYMGQIDTERQALNVARMQ
LLGAEVIAVEAGSRTLKDAMNEAMRDWVAHVEDTHYLIGTASGPHPFPKLVREFQRVISAEARQQCLDRVGRLPDAICAC
VGGGSNAIGSFAEFIDDPEVRLYGFEAGGDGVETGRHAASITRGSVGVLHGTRTYILQDPDGQTMESHSISAGLDYPGVG
PEHSWLAARKRATYLPVNDREAMEALRTLTRTEGIMPAIESAHAVAGVLKIAKDLPAHDGEPSVVIVTVSGRGDKDVDTA
LEWFAMDGSVDATTGGME
>Mature_417_residues
SARDLPDARGHFDRFGGRFVPEALQAALSQLTGTFEAAVTDPDFLTELEDLRREYAGRPSPLTEAPRFSQYIFQQTGHQV
RVLLKREDLNHTGSHKINNVLGQALLTRKMGKRRLIAETGAGQHGVATATVAAMMGMECRIYMGQIDTERQALNVARMQL
LGAEVIAVEAGSRTLKDAMNEAMRDWVAHVEDTHYLIGTASGPHPFPKLVREFQRVISAEARQQCLDRVGRLPDAICACV
GGGSNAIGSFAEFIDDPEVRLYGFEAGGDGVETGRHAASITRGSVGVLHGTRTYILQDPDGQTMESHSISAGLDYPGVGP
EHSWLAARKRATYLPVNDREAMEALRTLTRTEGIMPAIESAHAVAGVLKIAKDLPAHDGEPSVVIVTVSGRGDKDVDTAL
EWFAMDGSVDATTGGME

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=399, Percent_Identity=51.8796992481203, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321412, Length=391, Percent_Identity=50.6393861892583, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45217; Mature: 45085

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARDLPDARGHFDRFGGRFVPEALQAALSQLTGTFEAAVTDPDFLTELEDLRREYAGRP
CCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCC
SPLTEAPRFSQYIFQQTGHQVRVLLKREDLNHTGSHKINNVLGQALLTRKMGKRRLIAET
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHC
GAGQHGVATATVAAMMGMECRIYMGQIDTERQALNVARMQLLGAEVIAVEAGSRTLKDAM
CCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
NEAMRDWVAHVEDTHYLIGTASGPHPFPKLVREFQRVISAEARQQCLDRVGRLPDAICAC
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VGGGSNAIGSFAEFIDDPEVRLYGFEAGGDGVETGRHAASITRGSVGVLHGTRTYILQDP
HCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHCCCHHHHHCCCCEEEEECCEEEEEECC
DGQTMESHSISAGLDYPGVGPEHSWLAARKRATYLPVNDREAMEALRTLTRTEGIMPAIE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCCHHHHH
SAHAVAGVLKIAKDLPAHDGEPSVVIVTVSGRGDKDVDTALEWFAMDGSVDATTGGME
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SARDLPDARGHFDRFGGRFVPEALQAALSQLTGTFEAAVTDPDFLTELEDLRREYAGRP
CCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCC
SPLTEAPRFSQYIFQQTGHQVRVLLKREDLNHTGSHKINNVLGQALLTRKMGKRRLIAET
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHC
GAGQHGVATATVAAMMGMECRIYMGQIDTERQALNVARMQLLGAEVIAVEAGSRTLKDAM
CCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
NEAMRDWVAHVEDTHYLIGTASGPHPFPKLVREFQRVISAEARQQCLDRVGRLPDAICAC
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VGGGSNAIGSFAEFIDDPEVRLYGFEAGGDGVETGRHAASITRGSVGVLHGTRTYILQDP
HCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHCCCHHHHHCCCCEEEEECCEEEEEECC
DGQTMESHSISAGLDYPGVGPEHSWLAARKRATYLPVNDREAMEALRTLTRTEGIMPAIE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCCHHHHH
SAHAVAGVLKIAKDLPAHDGEPSVVIVTVSGRGDKDVDTALEWFAMDGSVDATTGGME
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA