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The map label for this gene is cobT [H]

Identifier: 50842437

GI number: 50842437

Start: 1034762

End: 1036528

Strand: Reverse

Name: cobT [H]

Synonym: PPA0953

Alternate gene names: 50842437

Gene position: 1036528-1034762 (Counterclockwise)

Preceding gene: 50842440

Following gene: 50842432

Centisome position: 40.49

GC content: 65.99

Gene sequence:

>1767_bases
GTGATCATCCCTGACGAGAACCCATCTACCAGCCGGCGCTGGGACCGCCCTATTCCCCGAATCGGAGACACCACTTCTTC
TGCCACCCGAGCCGCAGCTCCCACCGGATGGTCCCTGGGCGACCAGGTACAACAGGGGCTGGACACCGCTATCGATACTC
GACGTGACATCCGCCGTTACCGCCACGACGACGTCCCCAAAGAACTCGTCAACACCGTGTTGTGGGCCGGCCATCGCGCT
CCGAGCGTTGGCCATAGCCAGCCGTGGCGGTTCATCGTGGTGCGCGACGCCGACATTCGTGATCGCGCTGCCGTGATGGC
CGACCGAGAGCGACTGCGTCAGGCTGAACTCCTCACCCCCGATCGGCGTGCCCACCTCCTCGACCTCCAGCTCGAGGGGA
TCCGCGAGGCCCCCGTCGGCATCGTCGTCGCATGTGACCGTCGAGCACCGGCCTCAGGGGTACTGGGACGCAACACGTTC
ACCGACGCCGACATGTGGAGTTGCGCCTGTGCCGTCGAGAATATGTGGCTCACTGCCCGAGCTCACGGCCTGGGGATGGG
GTGGGTGACCCTCTTCCAGCCCGAAGAACTGGCCGAACTACTTCACCTTCCGAACGACGTTGAGACCCTGGGTTGGCTAT
GCCTAGGATGGCCCGACGAACGTCCTCCGGCTCCTGGCCTTGAGAGGCGCGGTTGGTCGCGTCGTGTGCCGCTCAGCGAC
GTCACCTTGGCGGACCGCTGGCCCGATAGTGCTCAGCCTGAGGCACCCGTTTCGGCCTTGCGTCAGACCCTGCACTCCCC
CAATCGTTACCAGGTTGTCGCCGCTCACGACGACGCTGACCAGCTCCTCACCCCGCCCGGGTCTCTCGGCCTGCTCGACC
AGACCCTCGACCGAGTCGAGGCTGCGGGTGGAACCGAGATCACCGGCGGCACCCTTGTCTTAGTCGGAGCGGACCACCCC
GTCGCTCACCTCGACGTCACGGCGTTCGAGGCCTCGGTGACCCACGACGTCATGGCAGCCTCTGTCGCCGGAACCGGGCT
GGGCGTTTCCACCGCAACTGCCGCCGGGCTGTCCCACCTTGTCGTCGACGCCGGGGTTGCTCAGCCGGTACAGGGTGCCA
GGTCCGTCCGCATCCGCGGAGAGCGTGGCGACCTCCGCCACGCTGACGCCATGACCCCTGTCCAGGTAGAAGCTCTGCTG
CGCGACGGGCAGGCCCTGGGGGCAGAAGCATCCCATGATGGACTGGTATGTCTCGGCGAAGTCGGGGTCGGTAACACCAC
CATCGCCACAGCCCTAGCCTGCGCTATGACCGGGTTGGGCCCCGACGAGGCCGTCGGTTTGGGAGCTGGAAGCGATACCG
CCATGGTGGAACGTAAGGCCGAGATCATCAAGGCTGCTCTGACCCGTACTCACACCGACCCCAACGACCCCGAGCGCCTT
CTTGCCGCCTTGGGAGGCCCTGAGTTCGCTGTTCTGGCAGGGGTGTGCCTGGGTGCCGCCGAGGCCGGCTCCCCGGTGGT
CCTTGACGGTCTGGCTACCAGCGTCGCAGCCCTCATCGCGACCAAGTTCTCGCCGGGTCTCCACGGCTGGCTCGTCGCTT
CGCAGGCATCACGAGAACAGGTTCATCACATTGTGCTGGCTGAGTTAGGCCTGGAAGCCCTCATGGAGTTGCGGATGCGC
GCTGGCGAAGGCGTCGGAGCATGTTTTGGGGCCCAGATGATTCTCACCGGTCTGCAGGTTCGCCGTACCGCCGCGCGAAC
CTGCTGA

Upstream 100 bases:

>100_bases
ACCGTCGTGCCAGCGCCAGTGGCACAACGAGAAATCACGACCCGCATTGCCACACCATCCCGGCCACAGGCCGCTGCGGG
CCGAGCACTACCCTCATGCT

Downstream 100 bases:

>100_bases
GCTCGTGAACTTGTTTTCTTTAACCTTCTCTCCACATCATCGACGTCGTCACCGAGGAAGGACCGCCGTGTCGGCACCAT
CACCCACTTCGCCCCGATTC

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MIIPDENPSTSRRWDRPIPRIGDTTSSATRAAAPTGWSLGDQVQQGLDTAIDTRRDIRRYRHDDVPKELVNTVLWAGHRA
PSVGHSQPWRFIVVRDADIRDRAAVMADRERLRQAELLTPDRRAHLLDLQLEGIREAPVGIVVACDRRAPASGVLGRNTF
TDADMWSCACAVENMWLTARAHGLGMGWVTLFQPEELAELLHLPNDVETLGWLCLGWPDERPPAPGLERRGWSRRVPLSD
VTLADRWPDSAQPEAPVSALRQTLHSPNRYQVVAAHDDADQLLTPPGSLGLLDQTLDRVEAAGGTEITGGTLVLVGADHP
VAHLDVTAFEASVTHDVMAASVAGTGLGVSTATAAGLSHLVVDAGVAQPVQGARSVRIRGERGDLRHADAMTPVQVEALL
RDGQALGAEASHDGLVCLGEVGVGNTTIATALACAMTGLGPDEAVGLGAGSDTAMVERKAEIIKAALTRTHTDPNDPERL
LAALGGPEFAVLAGVCLGAAEAGSPVVLDGLATSVAALIATKFSPGLHGWLVASQASREQVHHIVLAELGLEALMELRMR
AGEGVGACFGAQMILTGLQVRRTAARTC

Sequences:

>Translated_588_residues
MIIPDENPSTSRRWDRPIPRIGDTTSSATRAAAPTGWSLGDQVQQGLDTAIDTRRDIRRYRHDDVPKELVNTVLWAGHRA
PSVGHSQPWRFIVVRDADIRDRAAVMADRERLRQAELLTPDRRAHLLDLQLEGIREAPVGIVVACDRRAPASGVLGRNTF
TDADMWSCACAVENMWLTARAHGLGMGWVTLFQPEELAELLHLPNDVETLGWLCLGWPDERPPAPGLERRGWSRRVPLSD
VTLADRWPDSAQPEAPVSALRQTLHSPNRYQVVAAHDDADQLLTPPGSLGLLDQTLDRVEAAGGTEITGGTLVLVGADHP
VAHLDVTAFEASVTHDVMAASVAGTGLGVSTATAAGLSHLVVDAGVAQPVQGARSVRIRGERGDLRHADAMTPVQVEALL
RDGQALGAEASHDGLVCLGEVGVGNTTIATALACAMTGLGPDEAVGLGAGSDTAMVERKAEIIKAALTRTHTDPNDPERL
LAALGGPEFAVLAGVCLGAAEAGSPVVLDGLATSVAALIATKFSPGLHGWLVASQASREQVHHIVLAELGLEALMELRMR
AGEGVGACFGAQMILTGLQVRRTAARTC
>Mature_588_residues
MIIPDENPSTSRRWDRPIPRIGDTTSSATRAAAPTGWSLGDQVQQGLDTAIDTRRDIRRYRHDDVPKELVNTVLWAGHRA
PSVGHSQPWRFIVVRDADIRDRAAVMADRERLRQAELLTPDRRAHLLDLQLEGIREAPVGIVVACDRRAPASGVLGRNTF
TDADMWSCACAVENMWLTARAHGLGMGWVTLFQPEELAELLHLPNDVETLGWLCLGWPDERPPAPGLERRGWSRRVPLSD
VTLADRWPDSAQPEAPVSALRQTLHSPNRYQVVAAHDDADQLLTPPGSLGLLDQTLDRVEAAGGTEITGGTLVLVGADHP
VAHLDVTAFEASVTHDVMAASVAGTGLGVSTATAAGLSHLVVDAGVAQPVQGARSVRIRGERGDLRHADAMTPVQVEALL
RDGQALGAEASHDGLVCLGEVGVGNTTIATALACAMTGLGPDEAVGLGAGSDTAMVERKAEIIKAALTRTHTDPNDPERL
LAALGGPEFAVLAGVCLGAAEAGSPVVLDGLATSVAALIATKFSPGLHGWLVASQASREQVHHIVLAELGLEALMELRMR
AGEGVGACFGAQMILTGLQVRRTAARTC

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=303, Percent_Identity=35.973597359736, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 62314; Mature: 62314

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIPDENPSTSRRWDRPIPRIGDTTSSATRAAAPTGWSLGDQVQQGLDTAIDTRRDIRRY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RHDDVPKELVNTVLWAGHRAPSVGHSQPWRFIVVRDADIRDRAAVMADRERLRQAELLTP
HCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
DRRAHLLDLQLEGIREAPVGIVVACDRRAPASGVLGRNTFTDADMWSCACAVENMWLTAR
CCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCEEEEEE
AHGLGMGWVTLFQPEELAELLHLPNDVETLGWLCLGWPDERPPAPGLERRGWSRRVPLSD
CCCCCCCEEEEECHHHHHHHHHCCCCHHHHCEEEECCCCCCCCCCCHHHCCCCCCCCCCC
VTLADRWPDSAQPEAPVSALRQTLHSPNRYQVVAAHDDADQLLTPPGSLGLLDQTLDRVE
CEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHH
AAGGTEITGGTLVLVGADHPVAHLDVTAFEASVTHDVMAASVAGTGLGVSTATAAGLSHL
HCCCCEECCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VVDAGVAQPVQGARSVRIRGERGDLRHADAMTPVQVEALLRDGQALGAEASHDGLVCLGE
HHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCEEEEEC
VGVGNTTIATALACAMTGLGPDEAVGLGAGSDTAMVERKAEIIKAALTRTHTDPNDPERL
CCCCCHHHHHHHHHHHHCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LAALGGPEFAVLAGVCLGAAEAGSPVVLDGLATSVAALIATKFSPGLHGWLVASQASREQ
HHHHCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHH
VHHIVLAELGLEALMELRMRAGEGVGACFGAQMILTGLQVRRTAARTC
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIPDENPSTSRRWDRPIPRIGDTTSSATRAAAPTGWSLGDQVQQGLDTAIDTRRDIRRY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RHDDVPKELVNTVLWAGHRAPSVGHSQPWRFIVVRDADIRDRAAVMADRERLRQAELLTP
HCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
DRRAHLLDLQLEGIREAPVGIVVACDRRAPASGVLGRNTFTDADMWSCACAVENMWLTAR
CCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCEEEEEE
AHGLGMGWVTLFQPEELAELLHLPNDVETLGWLCLGWPDERPPAPGLERRGWSRRVPLSD
CCCCCCCEEEEECHHHHHHHHHCCCCHHHHCEEEECCCCCCCCCCCHHHCCCCCCCCCCC
VTLADRWPDSAQPEAPVSALRQTLHSPNRYQVVAAHDDADQLLTPPGSLGLLDQTLDRVE
CEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHCCCCCCCCHHHHHHHHHH
AAGGTEITGGTLVLVGADHPVAHLDVTAFEASVTHDVMAASVAGTGLGVSTATAAGLSHL
HCCCCEECCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
VVDAGVAQPVQGARSVRIRGERGDLRHADAMTPVQVEALLRDGQALGAEASHDGLVCLGE
HHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCEEEEEC
VGVGNTTIATALACAMTGLGPDEAVGLGAGSDTAMVERKAEIIKAALTRTHTDPNDPERL
CCCCCHHHHHHHHHHHHCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LAALGGPEFAVLAGVCLGAAEAGSPVVLDGLATSVAALIATKFSPGLHGWLVASQASREQ
HHHHCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHH
VHHIVLAELGLEALMELRMRAGEGVGACFGAQMILTGLQVRRTAARTC
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA