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The map label for this gene is fur [H]

Identifier: 50842432

GI number: 50842432

Start: 1028740

End: 1029153

Strand: Reverse

Name: fur [H]

Synonym: PPA0948

Alternate gene names: 50842432

Gene position: 1029153-1028740 (Counterclockwise)

Preceding gene: 50842437

Following gene: 50842430

Centisome position: 40.2

GC content: 57.0

Gene sequence:

>414_bases
GTGGAGAATCGGCGGCGCACGACCAAACAGCGCCTTGCCATTCGTGCTCTGTTTGACGACGAGCCGTTCTTCCTCACCGC
CCAGCAGGTCCATGATCAGCTACGCAACCGCGGAGATCAGGTTGGTCTGGCAACCGTCTATCGGAACTTGCAGACGATGG
CTGAGGACGGAGAGCTCGATGCCATTCGCGCTGAAGACGGCGAAATGACCTATCGCCGTTGTTCCTCAGCGCACCACCAT
CACTTGGTATGCCGCAATTGCGGCAAGGCTGTCGAAATTGGGCCTGAGAAAATCCTGGAGGATTGGACTCGCGATATCGC
CGCGAAATATGAGTTCAGCGAGACCGGCCACGAACTGGAATTGTTCGGAATCTGTTCGGAGTGCTCCGCAGTGCACACCA
GGTCAGTGTCGTAA

Upstream 100 bases:

>100_bases
CGCATGACTACCTCGTCAGCCAGCAGACAACCACTGGGAAATCGACAAGCTACTGGAGTACATTTGGCCTAGTTCGACCC
CCGGCAGTGAGGTGATCATG

Downstream 100 bases:

>100_bases
TCAGCGACGCAGCCGGGGGATGACTAAGCCCAGCTCGCATGCTCTCACGAGAACCTCAAGACGACTACGCACTCCCAGTT
TCTTTGCTAGATGACCAAGA

Product: metal uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MENRRRTTKQRLAIRALFDDEPFFLTAQQVHDQLRNRGDQVGLATVYRNLQTMAEDGELDAIRAEDGEMTYRRCSSAHHH
HLVCRNCGKAVEIGPEKILEDWTRDIAAKYEFSETGHELELFGICSECSAVHTRSVS

Sequences:

>Translated_137_residues
MENRRRTTKQRLAIRALFDDEPFFLTAQQVHDQLRNRGDQVGLATVYRNLQTMAEDGELDAIRAEDGEMTYRRCSSAHHH
HLVCRNCGKAVEIGPEKILEDWTRDIAAKYEFSETGHELELFGICSECSAVHTRSVS
>Mature_137_residues
MENRRRTTKQRLAIRALFDDEPFFLTAQQVHDQLRNRGDQVGLATVYRNLQTMAEDGELDAIRAEDGEMTYRRCSSAHHH
HLVCRNCGKAVEIGPEKILEDWTRDIAAKYEFSETGHELELFGICSECSAVHTRSVS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=123, Percent_Identity=34.1463414634146, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15708; Mature: 15708

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRRRTTKQRLAIRALFDDEPFFLTAQQVHDQLRNRGDQVGLATVYRNLQTMAEDGELD
CCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEE
AIRAEDGEMTYRRCSSAHHHHLVCRNCGKAVEIGPEKILEDWTRDIAAKYEFSETGHELE
EEECCCCCHHHHHHCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCEEE
LFGICSECSAVHTRSVS
EEEEHHHHHHHHHCCCC
>Mature Secondary Structure
MENRRRTTKQRLAIRALFDDEPFFLTAQQVHDQLRNRGDQVGLATVYRNLQTMAEDGELD
CCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEE
AIRAEDGEMTYRRCSSAHHHHLVCRNCGKAVEIGPEKILEDWTRDIAAKYEFSETGHELE
EEECCCCCHHHHHHCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCEEE
LFGICSECSAVHTRSVS
EEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA