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The map label for this gene is glyQS [H]

Identifier: 50842433

GI number: 50842433

Start: 1029249

End: 1030769

Strand: Direct

Name: glyQS [H]

Synonym: PPA0949

Alternate gene names: 50842433

Gene position: 1029249-1030769 (Clockwise)

Preceding gene: 50842431

Following gene: 50842434

Centisome position: 40.2

GC content: 57.59

Gene sequence:

>1521_bases
ATGCGTAGTGTAGTTACCGTTAAGCTAGTTAACGGCCTCGCCGCCCAGATATGTTCCGTAGGCGGCGCTGCCCGCGTGGG
CGCCATCCGGGTGTCCACTCCAATGAGGACTTGGAAGAAAGGGACGGCTGTGGCCTCCACTAGCACACTCGACAATGTCA
TCAACCTCTGTAAGCGACGCGGATTCGTTTTCCCGTGTGGGGAGATCTATGGCGGCACCCGTGCTGCGTGGGATTACGGC
CCATTCGGCGTCGAGCTTAAGGAGAACATTAAGAGGCAGTGGTGGCGTGCCATGGTCACCCGTCGCGATGACGTCGTTGG
TCTTGACTCCTCGGTCATCCTGCCTCGTGAGGTGTGGGTGGCCTCGGGACACGTCGGAGTGTTCAACGACCCTCTGACCG
AGTGCCTGTCGTGTCACAAGCGGATGCGCGCTGATCATCTACAGGAGGGCCACGCCGCCAAGCACGGGATCGCCGACCCT
GATTCCATCTCGCTCGAGGAGGTCAACTGTCCCAACTGCGGCAACAAGGGGCAGTGGACCGAACCCCGAGACTTCAACAT
GATGCTTAAGACCTACCTCGGCCCCGTCGAGGATAAGTCGGGTCTGCACTACCTGCGTCCCGAGACCGCCCAGGGCATTT
TCGTCAATTTCCAGAACGTGCTCACCAGTGCCCGCAAGAAGCCGCCATTCGGCATCGCGCAGACAGGTAAGTCGTTCCGC
AACGAGATCACGCCTGGGAACTTCATCTTCCGTACCCGTGAGTTCGAGCAGATGGAGATGGAGTTCTTCGTCGAACCCGG
AACCGACGAGGAGTGGCATCAGTACTGGATCGACGTTCGCACCGCGTGGTACACCGATCTCGGCATCAACCCGGATAACC
TGCGCCACTACGAGCATCCTAAAGAAAAGCTCTCCCACTACTCGAAGCGCACTGTCGACGTTGAGTACAAGTTTGGGTTT
TCCGGGTCTGACTGGGGTGAGCTTGAAGGTATTGCTAACCGTACTGATTTCGATTTGGGTAACCATTCCAGGCACTCTGG
TAAGGATCTGTCGTACTACGACCAGGCCAACAACAAGCGCTACTTGCCTTATGTTATTGAGCCGGCGGCAGGATTGACTC
GATCGCTCATGGCCTTCATGGTGGATGCTTACACCGAGGATGAGGCACCCAACGCCAAGGGTGGGGTTGACAAGCGCACC
GTGCTTAAGCTGGATCCGCGTCTTTCTCCGGTCAAGGCTGCGGTGCTGCCACTGAGCCGTAATTCTGACTTGTCGCCGAA
GGCCCGCGATCTTGCTGCTCGTTTACGTGAGCATTGGAATGTTGACTTCGACGATGCCCAGGCTATTGGCAAGCGCTACC
GCCGTCAGGACGAGATTGGTACCCCGTTCTGCATCACCGTCGACTTCGATTCCCTTGAGGATGACGCCGTGACGATTCGT
GAGCGTGACACCATGGCTCAGCAGCGTGTCAGCATTGACAAGGTTGAGGAATACCTCGGCGGTAAACTTCTCGGCTGCTG
A

Upstream 100 bases:

>100_bases
TCCACCATGATCACCTCACTGCCGGGGGTCGAACTAGGCCAAATGTACTCCAGTAGCTTGTCGATTTCCCAGTGGTTGTC
TGCTGGCTGACGAGGTAGTC

Downstream 100 bases:

>100_bases
TCTGCTATACCTTTTATGCACGAAAGCATCTCGGCACACCGGGGTCGGGGCACTCACGACGATTATCCTGACCCCGGTGT
CGTTGGAGAAAACATCATCG

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MRSVVTVKLVNGLAAQICSVGGAARVGAIRVSTPMRTWKKGTAVASTSTLDNVINLCKRRGFVFPCGEIYGGTRAAWDYG
PFGVELKENIKRQWWRAMVTRRDDVVGLDSSVILPREVWVASGHVGVFNDPLTECLSCHKRMRADHLQEGHAAKHGIADP
DSISLEEVNCPNCGNKGQWTEPRDFNMMLKTYLGPVEDKSGLHYLRPETAQGIFVNFQNVLTSARKKPPFGIAQTGKSFR
NEITPGNFIFRTREFEQMEMEFFVEPGTDEEWHQYWIDVRTAWYTDLGINPDNLRHYEHPKEKLSHYSKRTVDVEYKFGF
SGSDWGELEGIANRTDFDLGNHSRHSGKDLSYYDQANNKRYLPYVIEPAAGLTRSLMAFMVDAYTEDEAPNAKGGVDKRT
VLKLDPRLSPVKAAVLPLSRNSDLSPKARDLAARLREHWNVDFDDAQAIGKRYRRQDEIGTPFCITVDFDSLEDDAVTIR
ERDTMAQQRVSIDKVEEYLGGKLLGC

Sequences:

>Translated_506_residues
MRSVVTVKLVNGLAAQICSVGGAARVGAIRVSTPMRTWKKGTAVASTSTLDNVINLCKRRGFVFPCGEIYGGTRAAWDYG
PFGVELKENIKRQWWRAMVTRRDDVVGLDSSVILPREVWVASGHVGVFNDPLTECLSCHKRMRADHLQEGHAAKHGIADP
DSISLEEVNCPNCGNKGQWTEPRDFNMMLKTYLGPVEDKSGLHYLRPETAQGIFVNFQNVLTSARKKPPFGIAQTGKSFR
NEITPGNFIFRTREFEQMEMEFFVEPGTDEEWHQYWIDVRTAWYTDLGINPDNLRHYEHPKEKLSHYSKRTVDVEYKFGF
SGSDWGELEGIANRTDFDLGNHSRHSGKDLSYYDQANNKRYLPYVIEPAAGLTRSLMAFMVDAYTEDEAPNAKGGVDKRT
VLKLDPRLSPVKAAVLPLSRNSDLSPKARDLAARLREHWNVDFDDAQAIGKRYRRQDEIGTPFCITVDFDSLEDDAVTIR
ERDTMAQQRVSIDKVEEYLGGKLLGC
>Mature_506_residues
MRSVVTVKLVNGLAAQICSVGGAARVGAIRVSTPMRTWKKGTAVASTSTLDNVINLCKRRGFVFPCGEIYGGTRAAWDYG
PFGVELKENIKRQWWRAMVTRRDDVVGLDSSVILPREVWVASGHVGVFNDPLTECLSCHKRMRADHLQEGHAAKHGIADP
DSISLEEVNCPNCGNKGQWTEPRDFNMMLKTYLGPVEDKSGLHYLRPETAQGIFVNFQNVLTSARKKPPFGIAQTGKSFR
NEITPGNFIFRTREFEQMEMEFFVEPGTDEEWHQYWIDVRTAWYTDLGINPDNLRHYEHPKEKLSHYSKRTVDVEYKFGF
SGSDWGELEGIANRTDFDLGNHSRHSGKDLSYYDQANNKRYLPYVIEPAAGLTRSLMAFMVDAYTEDEAPNAKGGVDKRT
VLKLDPRLSPVKAAVLPLSRNSDLSPKARDLAARLREHWNVDFDDAQAIGKRYRRQDEIGTPFCITVDFDSLEDDAVTIR
ERDTMAQQRVSIDKVEEYLGGKLLGC

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=354, Percent_Identity=31.3559322033898, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI70887790, Length=539, Percent_Identity=23.3766233766234, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32564541, Length=363, Percent_Identity=29.4765840220386, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17554996, Length=363, Percent_Identity=29.4765840220386, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6325338, Length=457, Percent_Identity=25.8205689277899, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6319597, Length=220, Percent_Identity=30.9090909090909, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24664462, Length=363, Percent_Identity=29.7520661157025, Blast_Score=155, Evalue=8e-38,
Organism=Drosophila melanogaster, GI21357965, Length=360, Percent_Identity=29.7222222222222, Blast_Score=155, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 57197; Mature: 57197

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS50862 AA_TRNA_LIGASE_II ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVVTVKLVNGLAAQICSVGGAARVGAIRVSTPMRTWKKGTAVASTSTLDNVINLCKRR
CCCEEEEHHHHHHHHHHHHCCCCHHCCEEEECCCHHHHHCCCCEECHHHHHHHHHHHHHC
GFVFPCGEIYGGTRAAWDYGPFGVELKENIKRQWWRAMVTRRDDVVGLDSSVILPREVWV
CCEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCEECCHHHEE
ASGHVGVFNDPLTECLSCHKRMRADHLQEGHAAKHGIADPDSISLEEVNCPNCGNKGQWT
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEECCCCCCCCCCCCCC
EPRDFNMMLKTYLGPVEDKSGLHYLRPETAQGIFVNFQNVLTSARKKPPFGIAQTGKSFR
CCCHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEHHHHHHHHHCCCCCCHHHCCHHHH
NEITPGNFIFRTREFEQMEMEFFVEPGTDEEWHQYWIDVRTAWYTDLGINPDNLRHYEHP
HCCCCCCEEEECCHHHHEEEEEEECCCCCHHHHHHHHHHHHEEEEECCCCHHHCCCCCCH
KEKLSHYSKRTVDVEYKFGFSGSDWGELEGIANRTDFDLGNHSRHSGKDLSYYDQANNKR
HHHHHHHHHCEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCE
YLPYVIEPAAGLTRSLMAFMVDAYTEDEAPNAKGGVDKRTVLKLDPRLSPVKAAVLPLSR
ECCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHEEEECCC
NSDLSPKARDLAARLREHWNVDFDDAQAIGKRYRRQDEIGTPFCITVDFDSLEDDAVTIR
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEH
ERDTMAQQRVSIDKVEEYLGGKLLGC
HHHHHHHHHHHHHHHHHHHCCEECCC
>Mature Secondary Structure
MRSVVTVKLVNGLAAQICSVGGAARVGAIRVSTPMRTWKKGTAVASTSTLDNVINLCKRR
CCCEEEEHHHHHHHHHHHHCCCCHHCCEEEECCCHHHHHCCCCEECHHHHHHHHHHHHHC
GFVFPCGEIYGGTRAAWDYGPFGVELKENIKRQWWRAMVTRRDDVVGLDSSVILPREVWV
CCEEECHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCEECCHHHEE
ASGHVGVFNDPLTECLSCHKRMRADHLQEGHAAKHGIADPDSISLEEVNCPNCGNKGQWT
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEECCCCCCCCCCCCCC
EPRDFNMMLKTYLGPVEDKSGLHYLRPETAQGIFVNFQNVLTSARKKPPFGIAQTGKSFR
CCCHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEHHHHHHHHHCCCCCCHHHCCHHHH
NEITPGNFIFRTREFEQMEMEFFVEPGTDEEWHQYWIDVRTAWYTDLGINPDNLRHYEHP
HCCCCCCEEEECCHHHHEEEEEEECCCCCHHHHHHHHHHHHEEEEECCCCHHHCCCCCCH
KEKLSHYSKRTVDVEYKFGFSGSDWGELEGIANRTDFDLGNHSRHSGKDLSYYDQANNKR
HHHHHHHHHCEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCE
YLPYVIEPAAGLTRSLMAFMVDAYTEDEAPNAKGGVDKRTVLKLDPRLSPVKAAVLPLSR
ECCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHEEEECCC
NSDLSPKARDLAARLREHWNVDFDDAQAIGKRYRRQDEIGTPFCITVDFDSLEDDAVTIR
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEH
ERDTMAQQRVSIDKVEEYLGGKLLGC
HHHHHHHHHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA