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The map label for this gene is yfiK [H]

Identifier: 50842431

GI number: 50842431

Start: 1028068

End: 1028739

Strand: Direct

Name: yfiK [H]

Synonym: PPA0947

Alternate gene names: 50842431

Gene position: 1028068-1028739 (Clockwise)

Preceding gene: 50842428

Following gene: 50842433

Centisome position: 40.15

GC content: 55.21

Gene sequence:

>672_bases
ATGTCAGTTCGACTCGTGGTTACTGACGATCATCCGATCATGAGGCAGGCTCTTGCCGGCTATTTCTCTCGTGTTGAGGA
GATGGAGGTTGTCGGCCAGGCCACTAATGGTCGTGAAGCCGTTGAGCTTGTTGATCAGCTATTGCCCGACGTTGTCCTTA
TGGACCTCAAGATGCCTGAAATGGACGGTCTCACAGCTACCCGAATGATCGTCTCGCGCCATCCTTCGGTCCGTGTTGTT
GCCCTGACGACTTTTGCTCGTCGGGATATCGTCGTTGAGGCCATCCTTGCTGGTGCTGCCGGATACCTTCTGAAGGAATC
TGAGCCGGAGGCCGTTATCGCAGGGGTTCGCGCTGTCATGGCAGGTCAAGTGACAGTGTCTCCGGAGATTGCCCGAGGTG
TTGTTGAGGTCTTTTCAGCTCGGCCCTGTGGTGGGGGGTCTCATCAGATTGATTTGACTCCGGTGAAATTGTCTGATGCT
GATGACGACGTTCTGAAGCTTCTCGCCGAAGGGTTGTCGAACGCTGCCATCGCAGATGAACTATGTCTCAGCGAGTCCGC
GGTTAAGCAGCGTCTTGGTCATCTAGCAAAGAAACTGGGAGTGCGTAGTCGTCTTGAGGTTCTCGTGAGAGCATGCGAGC
TGGGCTTAGTCATCCCCCGGCTGCGTCGCTGA

Upstream 100 bases:

>100_bases
CGCAGGCGTTATATGTCTGATCGTTGGCGCCGCGCGATCACCGTGGGTGAGGAGGTTCACTTGGGCTCAGCAGCGCCCAA
CGTGAGTGTAAGGAGGAGTG

Downstream 100 bases:

>100_bases
TTACGACACTGACCTGGTGTGCACTGCGGAGCACTCCGAACAGATTCCGAACAATTCCAGTTCGTGGCCGGTCTCGCTGA
ACTCATATTTCGCGGCGATA

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSVRLVVTDDHPIMRQALAGYFSRVEEMEVVGQATNGREAVELVDQLLPDVVLMDLKMPEMDGLTATRMIVSRHPSVRVV
ALTTFARRDIVVEAILAGAAGYLLKESEPEAVIAGVRAVMAGQVTVSPEIARGVVEVFSARPCGGGSHQIDLTPVKLSDA
DDDVLKLLAEGLSNAAIADELCLSESAVKQRLGHLAKKLGVRSRLEVLVRACELGLVIPRLRR

Sequences:

>Translated_223_residues
MSVRLVVTDDHPIMRQALAGYFSRVEEMEVVGQATNGREAVELVDQLLPDVVLMDLKMPEMDGLTATRMIVSRHPSVRVV
ALTTFARRDIVVEAILAGAAGYLLKESEPEAVIAGVRAVMAGQVTVSPEIARGVVEVFSARPCGGGSHQIDLTPVKLSDA
DDDVLKLLAEGLSNAAIADELCLSESAVKQRLGHLAKKLGVRSRLEVLVRACELGLVIPRLRR
>Mature_222_residues
SVRLVVTDDHPIMRQALAGYFSRVEEMEVVGQATNGREAVELVDQLLPDVVLMDLKMPEMDGLTATRMIVSRHPSVRVVA
LTTFARRDIVVEAILAGAAGYLLKESEPEAVIAGVRAVMAGQVTVSPEIARGVVEVFSARPCGGGSHQIDLTPVKLSDAD
DDVLKLLAEGLSNAAIADELCLSESAVKQRLGHLAKKLGVRSRLEVLVRACELGLVIPRLRR

Specific function: Member of the two-component regulatory system yfiJ/yfiK [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=203, Percent_Identity=34.4827586206897, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788222, Length=214, Percent_Identity=27.5700934579439, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787473, Length=205, Percent_Identity=34.1463414634146, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=25, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790102, Length=209, Percent_Identity=28.7081339712919, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=37.2549019607843, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082052, Length=149, Percent_Identity=29.5302013422819, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788546, Length=210, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=23.5576923076923, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24011; Mature: 23880

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRLVVTDDHPIMRQALAGYFSRVEEMEVVGQATNGREAVELVDQLLPDVVLMDLKMPE
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
MDGLTATRMIVSRHPSVRVVALTTFARRDIVVEAILAGAAGYLLKESEPEAVIAGVRAVM
CCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AGQVTVSPEIARGVVEVFSARPCGGGSHQIDLTPVKLSDADDDVLKLLAEGLSNAAIADE
HCCEEECHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHH
LCLSESAVKQRLGHLAKKLGVRSRLEVLVRACELGLVIPRLRR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVRLVVTDDHPIMRQALAGYFSRVEEMEVVGQATNGREAVELVDQLLPDVVLMDLKMPE
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
MDGLTATRMIVSRHPSVRVVALTTFARRDIVVEAILAGAAGYLLKESEPEAVIAGVRAVM
CCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AGQVTVSPEIARGVVEVFSARPCGGGSHQIDLTPVKLSDADDDVLKLLAEGLSNAAIADE
HCCEEECHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHH
LCLSESAVKQRLGHLAKKLGVRSRLEVLVRACELGLVIPRLRR
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]