| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is dnaJ1
Identifier: 50842400
GI number: 50842400
Start: 997143
End: 998321
Strand: Direct
Name: dnaJ1
Synonym: PPA0916
Alternate gene names: 50842400
Gene position: 997143-998321 (Clockwise)
Preceding gene: 50842399
Following gene: 50842401
Centisome position: 38.95
GC content: 59.54
Gene sequence:
>1179_bases TTGAGTAACGACTACTACGAGATTCTTGGCGTTTCCCATGATGCGAGTGCCGACGAGATCAAGAAGGCGTATCGCCGTAA GGCTATGAAACTCCACCCCGATGTTGCCGGGCCCGGATCAGAGGAGGAGTTCAAAAAGGTCCAAGAGGCTTATGAAATCC TCCAGGATCCGCAAAAGCGCGCCGTTTTTGATCGTGGCGGTGATCCCAACGCCCGGATGGGCGGGTTCGGCGAAGGCGGA TTTAGCAGTGCTGGATTCGATTTCACCAATCTTGTTGACGCGATGTTTGGTGGCAGCTCTCCCTTTGGTTCTGGTGGTGG CCGCGGCCCGCGCTCGCGTACCCGCCGTGGCCAGGACGCTCTGGTCCGAATGCGTCTTAGCCTCGCCGAGGCAGTTTTTG GCGTTACCAAGTCGTTAGAAGTCGACACCGCAGTGGTGTGCCCGAAATGCCAGGGTAAGGGCGCACAGTCCGGTTCCGAG CCTGTGACCTGCGATACCTGTCAGGGGCGCGGTGAGGTCATTACCGTGCAGCGCTCCTTCCTTGGTGATATCCGCACCAG CCAACCCTGCCCGACCTGCCATGGTTACGGTACGGTCATTCCTGATCCCTGCCAGGAGTGTTCCGGTGAGGGGAGGGTAC GCACCACTCGCACGATCAACGTCAAGATTCCCGCCGGAGTGGCTGACGGCAACCGCATCCATCTTGATTCCCGGGGAGAA GTCGGTCCCGGAGGTGGTCCGGCCGGTGACCTGTATATCGAGATGACGGTCAGTCCCCATGATGTCTTTACCCGTCACGG TGACGACCTCGAGATGGTTGTCACCATCCCGATGACGGCCGCAGCGCTGGGGACGAAGGTCCCCATGCACACGTTGGAAG CCGATCGCGAGGACTTCGCCGAGGATACTAAGACCGTCACTGTCGAGGTGCCGGCCGGAACCCAGTCCGGAACCCGGATC GTCGTTTCCGAACGAGGCGTGCCGAGGCTTCGTCGCAACGGGCGTGGTGATCTTGGTGTCACGTTCATCGTCCAGACACC GACGAAACTTGACTCCCACCAGAAGGATTTGCTGCGTCAGCTAGCTGAGGCTCGGGAAGAAACCAATGCTTCGGCGTCGG TAGAGAAATCAGGCGGTCGCGGCATGTTTTCCCGCATCAAGGAAGCTTTTGGCGGATGA
Upstream 100 bases:
>100_bases TGGCGTCGTCGGGCCGATCCGAATGGACTACCCCTCAACCATGGCAGCTGTGCGAGCCGTGGCCCGTTATGTGGGCCGGT TCCTGGCAGAAGGATGATTC
Downstream 100 bases:
>100_bases GTGACCCCTGCTTTCTTGGCGAGGTCGTCGCAGCTGTGCCCGGATCGGTGGTAGAAATCACCGGTGCAGAGGGCCACCAT GCTGGCTCGGTTCGACGCAT
Product: chaperone protein DnaJ2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 392; Mature: 391
Protein sequence:
>392_residues MSNDYYEILGVSHDASADEIKKAYRRKAMKLHPDVAGPGSEEEFKKVQEAYEILQDPQKRAVFDRGGDPNARMGGFGEGG FSSAGFDFTNLVDAMFGGSSPFGSGGGRGPRSRTRRGQDALVRMRLSLAEAVFGVTKSLEVDTAVVCPKCQGKGAQSGSE PVTCDTCQGRGEVITVQRSFLGDIRTSQPCPTCHGYGTVIPDPCQECSGEGRVRTTRTINVKIPAGVADGNRIHLDSRGE VGPGGGPAGDLYIEMTVSPHDVFTRHGDDLEMVVTIPMTAAALGTKVPMHTLEADREDFAEDTKTVTVEVPAGTQSGTRI VVSERGVPRLRRNGRGDLGVTFIVQTPTKLDSHQKDLLRQLAEAREETNASASVEKSGGRGMFSRIKEAFGG
Sequences:
>Translated_392_residues MSNDYYEILGVSHDASADEIKKAYRRKAMKLHPDVAGPGSEEEFKKVQEAYEILQDPQKRAVFDRGGDPNARMGGFGEGG FSSAGFDFTNLVDAMFGGSSPFGSGGGRGPRSRTRRGQDALVRMRLSLAEAVFGVTKSLEVDTAVVCPKCQGKGAQSGSE PVTCDTCQGRGEVITVQRSFLGDIRTSQPCPTCHGYGTVIPDPCQECSGEGRVRTTRTINVKIPAGVADGNRIHLDSRGE VGPGGGPAGDLYIEMTVSPHDVFTRHGDDLEMVVTIPMTAAALGTKVPMHTLEADREDFAEDTKTVTVEVPAGTQSGTRI VVSERGVPRLRRNGRGDLGVTFIVQTPTKLDSHQKDLLRQLAEAREETNASASVEKSGGRGMFSRIKEAFGG >Mature_391_residues SNDYYEILGVSHDASADEIKKAYRRKAMKLHPDVAGPGSEEEFKKVQEAYEILQDPQKRAVFDRGGDPNARMGGFGEGGF SSAGFDFTNLVDAMFGGSSPFGSGGGRGPRSRTRRGQDALVRMRLSLAEAVFGVTKSLEVDTAVVCPKCQGKGAQSGSEP VTCDTCQGRGEVITVQRSFLGDIRTSQPCPTCHGYGTVIPDPCQECSGEGRVRTTRTINVKIPAGVADGNRIHLDSRGEV GPGGGPAGDLYIEMTVSPHDVFTRHGDDLEMVVTIPMTAAALGTKVPMHTLEADREDFAEDTKTVTVEVPAGTQSGTRIV VSERGVPRLRRNGRGDLGVTFIVQTPTKLDSHQKDLLRQLAEAREETNASASVEKSGGRGMFSRIKEAFGG
Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon
COG id: COG0484
COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain
Gene ontology:
Cell location: Cytoplasm
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 J domain
Homologues:
Organism=Homo sapiens, GI4504511, Length=380, Percent_Identity=32.1052631578947, Blast_Score=176, Evalue=3e-44, Organism=Homo sapiens, GI194328760, Length=351, Percent_Identity=35.8974358974359, Blast_Score=172, Evalue=4e-43, Organism=Homo sapiens, GI194328758, Length=351, Percent_Identity=34.7578347578348, Blast_Score=172, Evalue=4e-43, Organism=Homo sapiens, GI205360838, Length=397, Percent_Identity=31.4861460957179, Blast_Score=163, Evalue=2e-40, Organism=Homo sapiens, GI205360840, Length=385, Percent_Identity=31.4285714285714, Blast_Score=162, Evalue=5e-40, Organism=Homo sapiens, GI5031741, Length=348, Percent_Identity=32.4712643678161, Blast_Score=148, Evalue=1e-35, Organism=Homo sapiens, GI194328762, Length=312, Percent_Identity=32.0512820512821, Blast_Score=132, Evalue=6e-31, Organism=Homo sapiens, GI7706495, Length=365, Percent_Identity=29.041095890411, Blast_Score=108, Evalue=8e-24, Organism=Homo sapiens, GI39204547, Length=384, Percent_Identity=25.2604166666667, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI201862587, Length=370, Percent_Identity=28.9189189189189, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI201862518, Length=370, Percent_Identity=28.9189189189189, Blast_Score=98, Evalue=1e-20, Organism=Homo sapiens, GI56549115, Length=370, Percent_Identity=28.9189189189189, Blast_Score=98, Evalue=2e-20, Organism=Homo sapiens, GI5453690, Length=216, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=8e-18, Organism=Homo sapiens, GI6631085, Length=213, Percent_Identity=33.8028169014084, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI194306642, Length=104, Percent_Identity=44.2307692307692, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI194306640, Length=104, Percent_Identity=44.2307692307692, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI23503241, Length=109, Percent_Identity=43.1192660550459, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI27151736, Length=110, Percent_Identity=44.5454545454545, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI88501736, Length=111, Percent_Identity=44.1441441441441, Blast_Score=80, Evalue=4e-15, Organism=Homo sapiens, GI17388799, Length=108, Percent_Identity=46.2962962962963, Blast_Score=77, Evalue=3e-14, Organism=Homo sapiens, GI47777312, Length=109, Percent_Identity=44.0366972477064, Blast_Score=77, Evalue=4e-14, Organism=Homo sapiens, GI4885495, Length=109, Percent_Identity=46.7889908256881, Blast_Score=77, Evalue=4e-14, Organism=Homo sapiens, GI22749377, Length=111, Percent_Identity=40.5405405405405, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI72534740, Length=107, Percent_Identity=38.3177570093458, Blast_Score=76, Evalue=5e-14, Organism=Homo sapiens, GI21553335, Length=76, Percent_Identity=46.0526315789474, Blast_Score=69, Evalue=8e-12, Organism=Homo sapiens, GI68077168, Length=87, Percent_Identity=42.5287356321839, Blast_Score=69, Evalue=8e-12, Organism=Homo sapiens, GI68077166, Length=87, Percent_Identity=42.5287356321839, Blast_Score=69, Evalue=9e-12, Organism=Homo sapiens, GI9558755, Length=113, Percent_Identity=37.1681415929204, Blast_Score=67, Evalue=4e-11, Organism=Escherichia coli, GI1786197, Length=365, Percent_Identity=43.5616438356164, Blast_Score=259, Evalue=2e-70, Organism=Escherichia coli, GI1787235, Length=368, Percent_Identity=30.4347826086957, Blast_Score=140, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17553096, Length=381, Percent_Identity=29.3963254593176, Blast_Score=152, Evalue=4e-37, Organism=Caenorhabditis elegans, GI17553098, Length=381, Percent_Identity=29.3963254593176, Blast_Score=151, Evalue=6e-37, Organism=Caenorhabditis elegans, GI17507263, Length=370, Percent_Identity=31.8918918918919, Blast_Score=139, Evalue=3e-33, Organism=Caenorhabditis elegans, GI212645553, Length=357, Percent_Identity=29.1316526610644, Blast_Score=103, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17534355, Length=123, Percent_Identity=39.0243902439024, Blast_Score=86, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17563890, Length=233, Percent_Identity=27.8969957081545, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17538236, Length=114, Percent_Identity=39.4736842105263, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI115532378, Length=88, Percent_Identity=37.5, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17554644, Length=100, Percent_Identity=41, Blast_Score=66, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324265, Length=369, Percent_Identity=31.1653116531165, Blast_Score=151, Evalue=2e-37, Organism=Saccharomyces cerevisiae, GI6323870, Length=373, Percent_Identity=31.0991957104558, Blast_Score=125, Evalue=1e-29, Organism=Saccharomyces cerevisiae, GI6321094, Length=419, Percent_Identity=28.8782816229117, Blast_Score=118, Evalue=2e-27, Organism=Saccharomyces cerevisiae, GI6323119, Length=389, Percent_Identity=25.9640102827763, Blast_Score=106, Evalue=7e-24, Organism=Saccharomyces cerevisiae, GI6324321, Length=128, Percent_Identity=39.0625, Blast_Score=75, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6322194, Length=106, Percent_Identity=40.5660377358491, Blast_Score=71, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6320888, Length=97, Percent_Identity=43.298969072165, Blast_Score=71, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6323813, Length=72, Percent_Identity=47.2222222222222, Blast_Score=69, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324103, Length=64, Percent_Identity=51.5625, Blast_Score=66, Evalue=9e-12, Organism=Drosophila melanogaster, GI24646562, Length=383, Percent_Identity=32.3759791122715, Blast_Score=149, Evalue=3e-36, Organism=Drosophila melanogaster, GI24646560, Length=383, Percent_Identity=32.3759791122715, Blast_Score=149, Evalue=3e-36, Organism=Drosophila melanogaster, GI24646558, Length=383, Percent_Identity=32.3759791122715, Blast_Score=149, Evalue=3e-36, Organism=Drosophila melanogaster, GI24646556, Length=383, Percent_Identity=32.3759791122715, Blast_Score=149, Evalue=3e-36, Organism=Drosophila melanogaster, GI21357547, Length=383, Percent_Identity=32.3759791122715, Blast_Score=149, Evalue=3e-36, Organism=Drosophila melanogaster, GI45552813, Length=410, Percent_Identity=28.780487804878, Blast_Score=148, Evalue=8e-36, Organism=Drosophila melanogaster, GI45549272, Length=410, Percent_Identity=28.780487804878, Blast_Score=147, Evalue=1e-35, Organism=Drosophila melanogaster, GI45552811, Length=410, Percent_Identity=28.780487804878, Blast_Score=147, Evalue=2e-35, Organism=Drosophila melanogaster, GI20129487, Length=353, Percent_Identity=30.028328611898, Blast_Score=122, Evalue=4e-28, Organism=Drosophila melanogaster, GI24584014, Length=353, Percent_Identity=30.028328611898, Blast_Score=122, Evalue=4e-28, Organism=Drosophila melanogaster, GI85726398, Length=381, Percent_Identity=27.0341207349081, Blast_Score=114, Evalue=1e-25, Organism=Drosophila melanogaster, GI19920464, Length=364, Percent_Identity=28.021978021978, Blast_Score=107, Evalue=1e-23, Organism=Drosophila melanogaster, GI28574949, Length=370, Percent_Identity=25.9459459459459, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI24658562, Length=69, Percent_Identity=53.6231884057971, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24658555, Length=69, Percent_Identity=53.6231884057971, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI17648033, Length=105, Percent_Identity=41.9047619047619, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI24584630, Length=105, Percent_Identity=41.9047619047619, Blast_Score=74, Evalue=3e-13, Organism=Drosophila melanogaster, GI18858081, Length=86, Percent_Identity=43.0232558139535, Blast_Score=72, Evalue=7e-13, Organism=Drosophila melanogaster, GI24668492, Length=69, Percent_Identity=44.9275362318841, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI21355911, Length=87, Percent_Identity=45.9770114942529, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI161077138, Length=65, Percent_Identity=47.6923076923077, Blast_Score=65, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DNAJ1_PROAC (Q6A997)
Other databases:
- EMBL: AE017283 - RefSeq: YP_055627.1 - ProteinModelPortal: Q6A997 - GeneID: 2932582 - GenomeReviews: AE017283_GR - KEGG: pac:PPA0916 - NMPDR: fig|267747.1.peg.904 - HOGENOM: HBG635315 - OMA: RDISTAY - ProtClustDB: CLSK2763599 - BioCyc: PACN267747:PPA0916-MONOMER - GO: GO:0005737 - HAMAP: MF_01152 - InterPro: IPR012724 - InterPro: IPR002939 - InterPro: IPR001623 - InterPro: IPR018253 - InterPro: IPR008971 - InterPro: IPR015609 - InterPro: IPR003095 - InterPro: IPR001305 - Gene3D: G3DSA:1.10.287.110 - Gene3D: G3DSA:2.10.230.10 - PANTHER: PTHR11821 - PRINTS: PR00625 - SMART: SM00271
Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep; SSF57938 HSP_DnaJ_cys-rich
EC number: NA
Molecular weight: Translated: 41911; Mature: 41780
Theoretical pI: Translated: 6.52; Mature: 6.52
Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2; PS51188 ZF_CR
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNDYYEILGVSHDASADEIKKAYRRKAMKLHPDVAGPGSEEEFKKVQEAYEILQDPQKR CCCCEEEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCHHHH AVFDRGGDPNARMGGFGEGGFSSAGFDFTNLVDAMFGGSSPFGSGGGRGPRSRTRRGQDA HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHH LVRMRLSLAEAVFGVTKSLEVDTAVVCPKCQGKGAQSGSEPVTCDTCQGRGEVITVQRSF HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCEEEEEHHH LGDIRTSQPCPTCHGYGTVIPDPCQECSGEGRVRTTRTINVKIPAGVADGNRIHLDSRGE HHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEECCCCC VGPGGGPAGDLYIEMTVSPHDVFTRHGDDLEMVVTIPMTAAALGTKVPMHTLEADREDFA CCCCCCCCCCEEEEEEECHHHHHHCCCCCEEEEEECCHHHHHHCCCCCHHHHHCCHHHHH EDTKTVTVEVPAGTQSGTRIVVSERGVPRLRRNGRGDLGVTFIVQTPTKLDSHQKDLLRQ CCCEEEEEEECCCCCCCCEEEEECCCCHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHH LAEAREETNASASVEKSGGRGMFSRIKEAFGG HHHHHHHCCCCCEEECCCCCHHHHHHHHHHCC >Mature Secondary Structure SNDYYEILGVSHDASADEIKKAYRRKAMKLHPDVAGPGSEEEFKKVQEAYEILQDPQKR CCCEEEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHCHHHH AVFDRGGDPNARMGGFGEGGFSSAGFDFTNLVDAMFGGSSPFGSGGGRGPRSRTRRGQDA HHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHH LVRMRLSLAEAVFGVTKSLEVDTAVVCPKCQGKGAQSGSEPVTCDTCQGRGEVITVQRSF HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCEEEEEHHH LGDIRTSQPCPTCHGYGTVIPDPCQECSGEGRVRTTRTINVKIPAGVADGNRIHLDSRGE HHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEECCCCC VGPGGGPAGDLYIEMTVSPHDVFTRHGDDLEMVVTIPMTAAALGTKVPMHTLEADREDFA CCCCCCCCCCEEEEEEECHHHHHHCCCCCEEEEEECCHHHHHHCCCCCHHHHHCCHHHHH EDTKTVTVEVPAGTQSGTRIVVSERGVPRLRRNGRGDLGVTFIVQTPTKLDSHQKDLLRQ CCCEEEEEEECCCCCCCCEEEEECCCCHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHH LAEAREETNASASVEKSGGRGMFSRIKEAFGG HHHHHHHCCCCCEEECCCCCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA