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The map label for this gene is yfmE [H]

Identifier: 50842280

GI number: 50842280

Start: 875384

End: 876196

Strand: Reverse

Name: yfmE [H]

Synonym: PPA0793

Alternate gene names: 50842280

Gene position: 876196-875384 (Counterclockwise)

Preceding gene: 50842281

Following gene: 50842279

Centisome position: 34.22

GC content: 57.2

Gene sequence:

>813_bases
GTGAGATTCCCCAGGGTCGTCCTTGCTGCCCTGGTCGGCATGAACCTTGCAACGTCGGGTGTGATTCTTCAAGCCGTGAT
GAGCAATCCCCTTGCCGATCCGAGCATCATCGGGGTCTCCTCGGGCGCAGGGCTTCTAGGAATAGGCACGCTGCTTATTT
TCCCAGAACGAGCAAACCTTGTACCTGTAATGGCGTTCATCGGTGCGATGTTGGCAGCTATGGCAATCTATGCACTCGCA
TGGAGGGGTGGCGTTCAACCACTGCGAATCATCCTTTCCGGGGTTGCCGTCTCAGCGCTGTGCGGCGCAGGGATCTCCGC
TGTCATGGTACTTATGGCCGACAATGTGCAAGGCGCTCTCATGTTCATGAATGGCAGCCTCGCCATGCGCAGTTGGGCCG
AGGTGTCCCTCATCTGGCCATATACCGTGGTAGGGATCATTGCCGCCGTTGTGCTGTCCCGCAGACTCGACATCATCACT
CTGGGTGATCAAGTTGCACAAGGCATGGGAATGAACGTTCAAGCGAATCGCCTTGTCCTCACTGCCGTGGCGGCCCTCCT
AGCCGCCAGCACAGTCAGCGCCATCGGGTTGCTCGGGTTCGTCGGTCTCATCGTGCCGCACATCATGCGGCTGATCGTCG
GAAATCGCCACGTCATCCTGGTTCCAGCGTGTGTGCTCGCCGGAGCTGCATTAGTTATGCTGAGCGACACATGCAGTCGG
GTCATCTTCGATCCTTTCGAGATACCGGTTGGCATCATGCTCACAGCACTGGGGGTTCCCTTCTTTCTTTTCCTCCTCAG
AAAGACATTGTGA

Upstream 100 bases:

>100_bases
AACAGGGATCGGGTTCGGTTCGATACAGTTGTCACCCTCTGACGTAGTCAAAGGATTGTTCGGTCCGTCCGATTTCCAAT
GGCATAGGGTGGTATGGGGA

Downstream 100 bases:

>100_bases
GATGGGAAATATCATGGAAACACCTATACTTTCCGGCTCCCACTTGAACGTCACCTTGGGCAATCACAAGATTCTCAATG
ACGTCTCCGTATCATTCCAG

Product: iron(III) dicitrate transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric-citrate import system permease protein [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRFPRVVLAALVGMNLATSGVILQAVMSNPLADPSIIGVSSGAGLLGIGTLLIFPERANLVPVMAFIGAMLAAMAIYALA
WRGGVQPLRIILSGVAVSALCGAGISAVMVLMADNVQGALMFMNGSLAMRSWAEVSLIWPYTVVGIIAAVVLSRRLDIIT
LGDQVAQGMGMNVQANRLVLTAVAALLAASTVSAIGLLGFVGLIVPHIMRLIVGNRHVILVPACVLAGAALVMLSDTCSR
VIFDPFEIPVGIMLTALGVPFFLFLLRKTL

Sequences:

>Translated_270_residues
MRFPRVVLAALVGMNLATSGVILQAVMSNPLADPSIIGVSSGAGLLGIGTLLIFPERANLVPVMAFIGAMLAAMAIYALA
WRGGVQPLRIILSGVAVSALCGAGISAVMVLMADNVQGALMFMNGSLAMRSWAEVSLIWPYTVVGIIAAVVLSRRLDIIT
LGDQVAQGMGMNVQANRLVLTAVAALLAASTVSAIGLLGFVGLIVPHIMRLIVGNRHVILVPACVLAGAALVMLSDTCSR
VIFDPFEIPVGIMLTALGVPFFLFLLRKTL
>Mature_270_residues
MRFPRVVLAALVGMNLATSGVILQAVMSNPLADPSIIGVSSGAGLLGIGTLLIFPERANLVPVMAFIGAMLAAMAIYALA
WRGGVQPLRIILSGVAVSALCGAGISAVMVLMADNVQGALMFMNGSLAMRSWAEVSLIWPYTVVGIIAAVVLSRRLDIIT
LGDQVAQGMGMNVQANRLVLTAVAALLAASTVSAIGLLGFVGLIVPHIMRLIVGNRHVILVPACVLAGAALVMLSDTCSR
VIFDPFEIPVGIMLTALGVPFFLFLLRKTL

Specific function: Part of the ABC transporter complex yfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=268, Percent_Identity=36.5671641791045, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=34.8920863309352, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786804, Length=268, Percent_Identity=30.5970149253731, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=30.4659498207885, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=32.6086956521739, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786805, Length=272, Percent_Identity=31.6176470588235, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 28058; Mature: 28058

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFPRVVLAALVGMNLATSGVILQAVMSNPLADPSIIGVSSGAGLLGIGTLLIFPERANL
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEEECCCCCH
VPVMAFIGAMLAAMAIYALAWRGGVQPLRIILSGVAVSALCGAGISAVMVLMADNVQGAL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEE
MFMNGSLAMRSWAEVSLIWPYTVVGIIAAVVLSRRLDIITLGDQVAQGMGMNVQANRLVL
EEECCCHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCCCCHHHHHH
TAVAALLAASTVSAIGLLGFVGLIVPHIMRLIVGNRHVILVPACVLAGAALVMLSDTCSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHH
VIFDPFEIPVGIMLTALGVPFFLFLLRKTL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MRFPRVVLAALVGMNLATSGVILQAVMSNPLADPSIIGVSSGAGLLGIGTLLIFPERANL
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHEEECCCCCH
VPVMAFIGAMLAAMAIYALAWRGGVQPLRIILSGVAVSALCGAGISAVMVLMADNVQGAL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEE
MFMNGSLAMRSWAEVSLIWPYTVVGIIAAVVLSRRLDIITLGDQVAQGMGMNVQANRLVL
EEECCCHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCCCCHHHHHH
TAVAALLAASTVSAIGLLGFVGLIVPHIMRLIVGNRHVILVPACVLAGAALVMLSDTCSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHH
VIFDPFEIPVGIMLTALGVPFFLFLLRKTL
HHCCHHHCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]