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The map label for this gene is lspA [H]

Identifier: 50842254

GI number: 50842254

Start: 842184

End: 842732

Strand: Direct

Name: lspA [H]

Synonym: PPA0767

Alternate gene names: 50842254

Gene position: 842184-842732 (Clockwise)

Preceding gene: 50842253

Following gene: 50842255

Centisome position: 32.89

GC content: 59.02

Gene sequence:

>549_bases
GTGCGTCAAGTGCAAGCAGCGCCAAGAGCGTCGGTGAGCTCTAACCCGACCGTGTTGGTAGGTGGGCAGCTGAAGCGCTG
GCGCGTCGTCATGGTCGCCATAGGTGTGCTCGGCTACGGACTTGATCAATGGACGAAAGCTGAGGCAGTTGCCCGTCTCG
ATCCTTACAACCCGCCGAGCTGGTTCGGTGGTTTCCTCACCCTGCGCCTGATCCGCAATCCCGGGGCGGCTTTTTCGATG
GGCTCGACAGCCACTGTGTTGATTAGCCTTTTTGCGATCGCCATGCTTATTGCCGTATGCGTGTGGGGGGTGCCTCGCGC
TCGTCATCGTTGGTCTCTTATTGCCTGCGGCATGCTCATTGCCGGGATCTGCGGCAATCTGACCGATCGGATTTTCCGAG
CCCCTGGTCCACTGCGTGGCCATGTTGTCGACTTCATGAGCCTGCCGCATTTCGCGGTATTCAACGTTGCCGACATATTC
ATCACGAGCACCGCCATACTCGTCGTAGTGGTGGCTGTGTTCGGGCACCACGAGGACGATGCAGGTTGA

Upstream 100 bases:

>100_bases
TGGCTCTTCAACTTCTCGACGGGGGCACCTGGGGAACCTGCGAATCCTGCGGTGAGCCGATTGGAAAAGCTCGGCTGCAG
GCGTTCCCGCGGGCCACCAT

Downstream 100 bases:

>100_bases
GATAGATGACCATTCATGAGATGTGATGAGTAGGAGGGGATGTGAGCGTCCTGTTAGTACCCGACGGTCTTGACGGGGAA
CGGGTCGATGTCGCTGCTGC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MRQVQAAPRASVSSNPTVLVGGQLKRWRVVMVAIGVLGYGLDQWTKAEAVARLDPYNPPSWFGGFLTLRLIRNPGAAFSM
GSTATVLISLFAIAMLIAVCVWGVPRARHRWSLIACGMLIAGICGNLTDRIFRAPGPLRGHVVDFMSLPHFAVFNVADIF
ITSTAILVVVVAVFGHHEDDAG

Sequences:

>Translated_182_residues
MRQVQAAPRASVSSNPTVLVGGQLKRWRVVMVAIGVLGYGLDQWTKAEAVARLDPYNPPSWFGGFLTLRLIRNPGAAFSM
GSTATVLISLFAIAMLIAVCVWGVPRARHRWSLIACGMLIAGICGNLTDRIFRAPGPLRGHVVDFMSLPHFAVFNVADIF
ITSTAILVVVVAVFGHHEDDAG
>Mature_182_residues
MRQVQAAPRASVSSNPTVLVGGQLKRWRVVMVAIGVLGYGLDQWTKAEAVARLDPYNPPSWFGGFLTLRLIRNPGAAFSM
GSTATVLISLFAIAMLIAVCVWGVPRARHRWSLIACGMLIAGICGNLTDRIFRAPGPLRGHVVDFMSLPHFAVFNVADIF
ITSTAILVVVVAVFGHHEDDAG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19610; Mature: 19610

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVQAAPRASVSSNPTVLVGGQLKRWRVVMVAIGVLGYGLDQWTKAEAVARLDPYNPPS
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
WFGGFLTLRLIRNPGAAFSMGSTATVLISLFAIAMLIAVCVWGVPRARHRWSLIACGMLI
HHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGICGNLTDRIFRAPGPLRGHVVDFMSLPHFAVFNVADIFITSTAILVVVVAVFGHHEDD
HHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AG
CC
>Mature Secondary Structure
MRQVQAAPRASVSSNPTVLVGGQLKRWRVVMVAIGVLGYGLDQWTKAEAVARLDPYNPPS
CCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHH
WFGGFLTLRLIRNPGAAFSMGSTATVLISLFAIAMLIAVCVWGVPRARHRWSLIACGMLI
HHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AGICGNLTDRIFRAPGPLRGHVVDFMSLPHFAVFNVADIFITSTAILVVVVAVFGHHEDD
HHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]