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The map label for this gene is gntK [H]

Identifier: 50842226

GI number: 50842226

Start: 810934

End: 811413

Strand: Reverse

Name: gntK [H]

Synonym: PPA0739

Alternate gene names: 50842226

Gene position: 811413-810934 (Counterclockwise)

Preceding gene: 50842229

Following gene: 50842225

Centisome position: 31.69

GC content: 56.25

Gene sequence:

>480_bases
ATGAGCGTCAACCACTTACACCGCCGCATGCCACTTATCGTCATCATGGGTGTAGCCGGAGCTGGGAAGACGGACATTGA
TTCCATGCTTGCCGAGCGTTTTGGTGTGGATTTCATGGACGGCGACGACCTTCATCCCCAGGCCAATATCGACAAGATGA
CATCGGGTTATCCTCTCAACGATGAGGACAGACGCCCCTGGCTAACTAATATCGCCGCTTGGATGGCCGAACGTGCTGAT
AACGGAGCAGTCGTGGCATGTTCCGCTCTCAAACATATCTACCGCGATCAGCTGCGAAAGACCTGCCCAGATCTGGTCTT
CGTCCATCTCGCTGGCGACCGCAAGATCGTTGCCAAACGGGTCGAGGCTCGCACCGGCCACTTCATGCCAACCAGCCTCA
TTGACTCCCATATACGCCACCCTCGAACCACTGGCCGCCGACGAGGCCGGCATCACTCTCAATTTCGACGATACTCGTGA

Upstream 100 bases:

>100_bases
CCCCAAAATATGAGTACAACTACTAAATACCTGTACAAATATGATCCCAACACATACGCTGGGTCAGGTCAACGAGGACC
ACGATTTCTGGGAGACCACC

Downstream 100 bases:

>100_bases
GGAACTCACCACGATGGCAGCAACCTGGTTGGCCGACGTCAACTGACATCGCACCCCGGACTCAAGGAGGAGTCAATGCC
CGTCATCCTCGAAACCGCAG

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSVNHLHRRMPLIVIMGVAGAGKTDIDSMLAERFGVDFMDGDDLHPQANIDKMTSGYPLNDEDRRPWLTNIAAWMAERAD
NGAVVACSALKHIYRDQLRKTCPDLVFVHLAGDRKIVAKRVEARTGHFMPTSLIDSHIRHPRTTGRRRGRHHSQFRRYS

Sequences:

>Translated_159_residues
MSVNHLHRRMPLIVIMGVAGAGKTDIDSMLAERFGVDFMDGDDLHPQANIDKMTSGYPLNDEDRRPWLTNIAAWMAERAD
NGAVVACSALKHIYRDQLRKTCPDLVFVHLAGDRKIVAKRVEARTGHFMPTSLIDSHIRHPRTTGRRRGRHHSQFRRYS
>Mature_158_residues
SVNHLHRRMPLIVIMGVAGAGKTDIDSMLAERFGVDFMDGDDLHPQANIDKMTSGYPLNDEDRRPWLTNIAAWMAERADN
GAVVACSALKHIYRDQLRKTCPDLVFVHLAGDRKIVAKRVEARTGHFMPTSLIDSHIRHPRTTGRRRGRHHSQFRRYS

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=147, Percent_Identity=38.0952380952381, Blast_Score=107, Evalue=6e-24,
Organism=Escherichia coli, GI87082265, Length=146, Percent_Identity=42.4657534246575, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1790719, Length=129, Percent_Identity=45.7364341085271, Blast_Score=123, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI25146487, Length=131, Percent_Identity=43.5114503816794, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320454, Length=142, Percent_Identity=40.8450704225352, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18125; Mature: 17994

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNHLHRRMPLIVIMGVAGAGKTDIDSMLAERFGVDFMDGDDLHPQANIDKMTSGYPLN
CCHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCC
DEDRRPWLTNIAAWMAERADNGAVVACSALKHIYRDQLRKTCPDLVFVHLAGDRKIVAKR
CCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHH
VEARTGHFMPTSLIDSHIRHPRTTGRRRGRHHSQFRRYS
HHHHCCCCCCHHHHHHHHCCCCHHHHHCCCCHHHHHCCC
>Mature Secondary Structure 
SVNHLHRRMPLIVIMGVAGAGKTDIDSMLAERFGVDFMDGDDLHPQANIDKMTSGYPLN
CHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCC
DEDRRPWLTNIAAWMAERADNGAVVACSALKHIYRDQLRKTCPDLVFVHLAGDRKIVAKR
CCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHH
VEARTGHFMPTSLIDSHIRHPRTTGRRRGRHHSQFRRYS
HHHHCCCCCCHHHHHHHHCCCCHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]