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The map label for this gene is gnuT [H]

Identifier: 50842225

GI number: 50842225

Start: 809488

End: 810858

Strand: Reverse

Name: gnuT [H]

Synonym: PPA0738

Alternate gene names: 50842225

Gene position: 810858-809488 (Counterclockwise)

Preceding gene: 50842226

Following gene: 50842222

Centisome position: 31.67

GC content: 59.3

Gene sequence:

>1371_bases
ATGCCCGTCATCCTCGAAACCGCAGCCAGTACCGGCCAACTGATTATGGCCACCCTCATCGGCTTCGCCACCATCGTTGC
CCTTATAACCAAGTTCAAACTCCACCCCTTCCTCTCCTTGACGATCGGTTCTTTAGTTGTCGGAGCTATCGCAAAGCTGT
CCCTGTCGGAGATATTGGCGTCCTATTCCAAAGGAGTCGGGTCGACGGTCGCTTCTGTCGGAGTCCTCATCGCCCTAGGA
GCGATTATCGGCAAGTTGTTAGCAGATTCCGGTGGCGCCGACGAAATCGTCGACACCCTAGTCTCTCAGGCTTCTCCCGC
CACCTTGCCATGGGCGATGGCCCTCATTGGCGCTGTCATTGGACTGCCCATGTTCTTCGAGATCGGTCTCGTCCTGCTCG
TTCCGGTCATCCTGCTGGTAACCCGCCGTTCCAAGCTGCCCCTCATGAGAGTAGCTATCCCGGCCCTGGCTGGCCTATCG
ACGATGCATGCCCTTGTTCCACCTCATCCGGGCCCATTGGCCGCCATTGGGCTGCTCAAAGCAGACCTCGGCATCACCCT
CGGGTTCGGTGTCCTTATTGCCATACCGACGGTTATTGCTGCTGGCCCGCTGTTCTCGCGGCTCGCAGCTCGGTGGGTGC
CCGTTGATGCGCCTGACCTCTTCCTTAATTCTGACGAGAATGGCCGTTGCGGTATTGCCCCTGGTCGCCCAAGGTTCTCC
GTCACCTTGATGACCGTCCTGCTACCTGTCGTCCTCATGATGGGCAAGGCCCTCGCCGATATCTTCGCTCTCAAAGGCAC
CGCCGTCCGCAGTATCTTGGATTTCCTTGGCGAGCCGATGTTTGCTTTGCTGCTGACAACCCTGCTGGCGATCTTTACCC
TGGGCAAGGCTTCCGGCATCAACCGGGACGCTATGAACAACAGTGTGGGGGCAGCGCTGCCCCCAATCGCTGGCATCTTA
CTCATCGTCGCCGCCGGCGGTGGGTTTAAGCAGATCCTCGTCGACACTGGTATTGCCAAGCTACTAGGCAACGGCATTAC
CCAGTCCTCGATCTCCCCGCTACTGATGGCCTGGCTCGTCGCTGTCGTCATCCGGTTGGCGACCGGCTCAGCGACGGTGG
CAACCGTCACCGCGGCCGGCATCCTGGAACCGGTGGCAGCCAGCTTGCCGCCCGCCCATGCGGCATTGCTGGTTCTAGCG
ATCGGCTGCGGTTCGGTTTTCTTCTCACACGTCAATGACGCCGGTTTCTGGCTCATCAAGGAATACTTCGGTATCTCGGT
GGGACAAACCATTAAGAGTTGGTCGCTCATGGAGACGGCGCTGTCAGTCTGCGGAGTGCTCCTGGTGCTGCTGGTCTCCG
TCATCGTCTGA

Upstream 100 bases:

>100_bases
CTCTCAATTTCGACGATACTCGTGAGGAACTCACCACGATGGCAGCAACCTGGTTGGCCGACGTCAACTGACATCGCACC
CCGGACTCAAGGAGGAGTCA

Downstream 100 bases:

>100_bases
CCTCACCGATACCTGACGCGCGACGGCCGGTCCCCGGATGAAGGAACCGGCCGTCACGTCAATCTGAGAACGTCACTGTT
CCTGGTGCTCACCTGAACCG

Product: gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MPVILETAASTGQLIMATLIGFATIVALITKFKLHPFLSLTIGSLVVGAIAKLSLSEILASYSKGVGSTVASVGVLIALG
AIIGKLLADSGGADEIVDTLVSQASPATLPWAMALIGAVIGLPMFFEIGLVLLVPVILLVTRRSKLPLMRVAIPALAGLS
TMHALVPPHPGPLAAIGLLKADLGITLGFGVLIAIPTVIAAGPLFSRLAARWVPVDAPDLFLNSDENGRCGIAPGRPRFS
VTLMTVLLPVVLMMGKALADIFALKGTAVRSILDFLGEPMFALLLTTLLAIFTLGKASGINRDAMNNSVGAALPPIAGIL
LIVAAGGGFKQILVDTGIAKLLGNGITQSSISPLLMAWLVAVVIRLATGSATVATVTAAGILEPVAASLPPAHAALLVLA
IGCGSVFFSHVNDAGFWLIKEYFGISVGQTIKSWSLMETALSVCGVLLVLLVSVIV

Sequences:

>Translated_456_residues
MPVILETAASTGQLIMATLIGFATIVALITKFKLHPFLSLTIGSLVVGAIAKLSLSEILASYSKGVGSTVASVGVLIALG
AIIGKLLADSGGADEIVDTLVSQASPATLPWAMALIGAVIGLPMFFEIGLVLLVPVILLVTRRSKLPLMRVAIPALAGLS
TMHALVPPHPGPLAAIGLLKADLGITLGFGVLIAIPTVIAAGPLFSRLAARWVPVDAPDLFLNSDENGRCGIAPGRPRFS
VTLMTVLLPVVLMMGKALADIFALKGTAVRSILDFLGEPMFALLLTTLLAIFTLGKASGINRDAMNNSVGAALPPIAGIL
LIVAAGGGFKQILVDTGIAKLLGNGITQSSISPLLMAWLVAVVIRLATGSATVATVTAAGILEPVAASLPPAHAALLVLA
IGCGSVFFSHVNDAGFWLIKEYFGISVGQTIKSWSLMETALSVCGVLLVLLVSVIV
>Mature_455_residues
PVILETAASTGQLIMATLIGFATIVALITKFKLHPFLSLTIGSLVVGAIAKLSLSEILASYSKGVGSTVASVGVLIALGA
IIGKLLADSGGADEIVDTLVSQASPATLPWAMALIGAVIGLPMFFEIGLVLLVPVILLVTRRSKLPLMRVAIPALAGLST
MHALVPPHPGPLAAIGLLKADLGITLGFGVLIAIPTVIAAGPLFSRLAARWVPVDAPDLFLNSDENGRCGIAPGRPRFSV
TLMTVLLPVVLMMGKALADIFALKGTAVRSILDFLGEPMFALLLTTLLAIFTLGKASGINRDAMNNSVGAALPPIAGILL
IVAAGGGFKQILVDTGIAKLLGNGITQSSISPLLMAWLVAVVIRLATGSATVATVTAAGILEPVAASLPPAHAALLVLAI
GCGSVFFSHVNDAGFWLIKEYFGISVGQTIKSWSLMETALSVCGVLLVLLVSVIV

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=437, Percent_Identity=40.7322654462243, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1790716, Length=438, Percent_Identity=40.4109589041096, Blast_Score=324, Evalue=7e-90,
Organism=Escherichia coli, GI1790776, Length=447, Percent_Identity=35.1230425055928, Blast_Score=286, Evalue=1e-78,
Organism=Escherichia coli, GI2367370, Length=432, Percent_Identity=36.5740740740741, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI48994939, Length=424, Percent_Identity=34.9056603773585, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1788707, Length=422, Percent_Identity=31.9905213270142, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1789097, Length=453, Percent_Identity=30.242825607064, Blast_Score=194, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46653; Mature: 46522

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVILETAASTGQLIMATLIGFATIVALITKFKLHPFLSLTIGSLVVGAIAKLSLSEILA
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYSKGVGSTVASVGVLIALGAIIGKLLADSGGADEIVDTLVSQASPATLPWAMALIGAVI
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLPMFFEIGLVLLVPVILLVTRRSKLPLMRVAIPALAGLSTMHALVPPHPGPLAAIGLLK
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ADLGITLGFGVLIAIPTVIAAGPLFSRLAARWVPVDAPDLFLNSDENGRCGIAPGRPRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCHH
VTLMTVLLPVVLMMGKALADIFALKGTAVRSILDFLGEPMFALLLTTLLAIFTLGKASGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
NRDAMNNSVGAALPPIAGILLIVAAGGGFKQILVDTGIAKLLGNGITQSSISPLLMAWLV
CHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AVVIRLATGSATVATVTAAGILEPVAASLPPAHAALLVLAIGCGSVFFSHVNDAGFWLIK
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EYFGISVGQTIKSWSLMETALSVCGVLLVLLVSVIV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PVILETAASTGQLIMATLIGFATIVALITKFKLHPFLSLTIGSLVVGAIAKLSLSEILA
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]