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The map label for this gene is ptsG [H]

Identifier: 50842162

GI number: 50842162

Start: 742472

End: 743860

Strand: Reverse

Name: ptsG [H]

Synonym: PPA0675

Alternate gene names: 50842162

Gene position: 743860-742472 (Counterclockwise)

Preceding gene: 50842168

Following gene: 50842158

Centisome position: 29.05

GC content: 61.12

Gene sequence:

>1389_bases
ATGGCGAAAGACGCTGTTGCCACCAGCACCAAGAAAAAACGGCAGATACCCGGGTTCTCCCAGATGCAGCGCATCGGGCG
CTCCCTCATGCTCCCGATCGCGTCCCTGCCGGTTGCCGCGCTGCTTATGCGGTTCGGGTCTGCTGACGTTCTCGGAGCGG
ACGGACTCGCCAAGCACGCATCATGGATGCAGCCGGTCGCTGACGTATTAGCCGGTGCAGGCGGCGCAATCTTCGACAAC
CTACCTCTCATCTTTGCGCTGGGTGTGGCCGTCGGGTACGCCAAGAAGGCCGATGGATCGACCGCCCTGGCAGCCCTCGT
CGGCTATCTCACCTTCACCGGTGCAGGCACCTCGGACAAGACCCAAGGAGGCGTGCTGCACGCCCTCGCTCCGTATTTCT
CGCAGAAGACCGGAGTCATCAATTACGGCGTCCTCGGCGGCATCGTCATCGGTCTTATCGCGGCCAAAATGTACGAGAAA
TACCGCCGTACCAAGCTGCCAACGTACCTAGCCTTCTTTGGCGGCCGCCGCCTCGTGCCAATTGTCACCGCCGCCGCTTC
CGTCGTCGCCGGCGTCATCATGGCTATCATTTACCCGGCCTTCGACTGGCTGTTCAATAAGCAGGTCGGCGGTTTCATCA
TGGCCCACGGGTCCAACCCAGGAACCGGATTCGTATTCGGCACCATCAACCGTCTCCTCATCCCCTTCGGCCTGCACCAC
CTGCTCAATTCGCTGCCGTGGTTCCAGCTCGGCAATTGCACCAACGCCGCCGGCGAGACTCTGCACGGTGACATCACCTG
CTTCTTCAGTGGTGCGTCCGGCACGAATGCCTGGACCGGTTCTTTCATGACTGGCTTCTTCCCCATCATGATGTTCGCCT
TGCCCGGAGCCGCCCTAGCGATCTACCACACGGCCAAGCCAGAGCGTAAGAAGCTCACCGGTGGCGTCATGATCTCAGTA
GCGCTGACGGCCTTCCTCACCGGTATCACCGAGCCCCTCGAGTATGCCTTCGCCTACGTCGCCTTCCCGCTGTACCTGGT
GCACGCGCTACTCACCGGGTCCTCCCTAGCGCTGTGCAACGCCTTGGGCATCAAGGACGGATTCGGTTTCTCGGCAGGTC
TGACTGACTACATCATCAACTTCGGACGGGCCTCGGAGCTTTCTGGTGGCCCCGGCAAGGTGCTCCTGCTCATCCTCATC
GGTTTGGTCTACGCCGTCATCTACTACGTCGTCTTCCGCTTCGCCATCACCAAGTGGAACCTGCGCACTCCCGGTCGCGA
AGACGAGGGTAACGACACCACCGGTGGCGCCAGTGTCTTCGATGAGGCCCAACTAGCTGCCAGCGAGTCCACCGGTAAGG
CAGACGCCCAAAAAGAGGGACGAATCTGA

Upstream 100 bases:

>100_bases
CTCTGCACGTTGTCTTGACATGGCCGCCTCAGTGGTCTGTACTTCGGCGAGTGGTCCATACCACCCCTTGAACATGAGCA
CTCACTGTGGAGGAACTCCT

Downstream 100 bases:

>100_bases
TCTTCGAGTCTCCTACTCTCATGATGGCGCCCCTTTGAATACTGAGGGCATCATCATAATGCGTCACAAACAACTCAGTC
ACTCTGCGGCGCTGGCATTA

Product: PTS system, glucose-specific IIBC component

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MAKDAVATSTKKKRQIPGFSQMQRIGRSLMLPIASLPVAALLMRFGSADVLGADGLAKHASWMQPVADVLAGAGGAIFDN
LPLIFALGVAVGYAKKADGSTALAALVGYLTFTGAGTSDKTQGGVLHALAPYFSQKTGVINYGVLGGIVIGLIAAKMYEK
YRRTKLPTYLAFFGGRRLVPIVTAAASVVAGVIMAIIYPAFDWLFNKQVGGFIMAHGSNPGTGFVFGTINRLLIPFGLHH
LLNSLPWFQLGNCTNAAGETLHGDITCFFSGASGTNAWTGSFMTGFFPIMMFALPGAALAIYHTAKPERKKLTGGVMISV
ALTAFLTGITEPLEYAFAYVAFPLYLVHALLTGSSLALCNALGIKDGFGFSAGLTDYIINFGRASELSGGPGKVLLLILI
GLVYAVIYYVVFRFAITKWNLRTPGREDEGNDTTGGASVFDEAQLAASESTGKADAQKEGRI

Sequences:

>Translated_462_residues
MAKDAVATSTKKKRQIPGFSQMQRIGRSLMLPIASLPVAALLMRFGSADVLGADGLAKHASWMQPVADVLAGAGGAIFDN
LPLIFALGVAVGYAKKADGSTALAALVGYLTFTGAGTSDKTQGGVLHALAPYFSQKTGVINYGVLGGIVIGLIAAKMYEK
YRRTKLPTYLAFFGGRRLVPIVTAAASVVAGVIMAIIYPAFDWLFNKQVGGFIMAHGSNPGTGFVFGTINRLLIPFGLHH
LLNSLPWFQLGNCTNAAGETLHGDITCFFSGASGTNAWTGSFMTGFFPIMMFALPGAALAIYHTAKPERKKLTGGVMISV
ALTAFLTGITEPLEYAFAYVAFPLYLVHALLTGSSLALCNALGIKDGFGFSAGLTDYIINFGRASELSGGPGKVLLLILI
GLVYAVIYYVVFRFAITKWNLRTPGREDEGNDTTGGASVFDEAQLAASESTGKADAQKEGRI
>Mature_461_residues
AKDAVATSTKKKRQIPGFSQMQRIGRSLMLPIASLPVAALLMRFGSADVLGADGLAKHASWMQPVADVLAGAGGAIFDNL
PLIFALGVAVGYAKKADGSTALAALVGYLTFTGAGTSDKTQGGVLHALAPYFSQKTGVINYGVLGGIVIGLIAAKMYEKY
RRTKLPTYLAFFGGRRLVPIVTAAASVVAGVIMAIIYPAFDWLFNKQVGGFIMAHGSNPGTGFVFGTINRLLIPFGLHHL
LNSLPWFQLGNCTNAAGETLHGDITCFFSGASGTNAWTGSFMTGFFPIMMFALPGAALAIYHTAKPERKKLTGGVMISVA
LTAFLTGITEPLEYAFAYVAFPLYLVHALLTGSSLALCNALGIKDGFGFSAGLTDYIINFGRASELSGGPGKVLLLILIG
LVYAVIYYVVFRFAITKWNLRTPGREDEGNDTTGGASVFDEAQLAASESTGKADAQKEGRI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=453, Percent_Identity=41.5011037527594, Blast_Score=311, Evalue=5e-86,
Organism=Escherichia coli, GI1786894, Length=410, Percent_Identity=46.0975609756098, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1787908, Length=450, Percent_Identity=32.2222222222222, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 48657; Mature: 48526

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AKDAVATSTKKKRQIPGFSQMQRIGRSLMLPIASLPVAALLMRFGSADVLGADGLAKHA
CCCHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SWMQPVADVLAGAGGAIFDNLPLIFALGVAVGYAKKADGSTALAALVGYLTFTGAGTSDK
HHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
TQGGVLHALAPYFSQKTGVINYGVLGGIVIGLIAAKMYEKYRRTKLPTYLAFFGGRRLVP
CCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHH
IVTAAASVVAGVIMAIIYPAFDWLFNKQVGGFIMAHGSNPGTGFVFGTINRLLIPFGLHH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHH
LLNSLPWFQLGNCTNAAGETLHGDITCFFSGASGTNAWTGSFMTGFFPIMMFALPGAALA
HHHCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
IYHTAKPERKKLTGGVMISVALTAFLTGITEPLEYAFAYVAFPLYLVHALLTGSSLALCN
EEECCCCHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ALGIKDGFGFSAGLTDYIINFGRASELSGGPGKVLLLILIGLVYAVIYYVVFRFAITKWN
HHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LRTPGREDEGNDTTGGASVFDEAQLAASESTGKADAQKEGRI
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA