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The map label for this gene is 50842168

Identifier: 50842168

GI number: 50842168

Start: 746343

End: 747545

Strand: Reverse

Name: 50842168

Synonym: PPA0681

Alternate gene names: NA

Gene position: 747545-746343 (Counterclockwise)

Preceding gene: 50842169

Following gene: 50842162

Centisome position: 29.2

GC content: 59.1

Gene sequence:

>1203_bases
GTGGCTCGAGACCGCCGACATTGTGGAGGATCAGTGACCCTTCAAGACGATAGCCCCATCTCCGGGAAGCGACCGGCCTC
ATCCCTCTTCTGGCCAGCAATCGCGGTCATCATGACGACGGTGACGTGGACGTTGGCCATGCCGCGCCCAACCGACCTAA
AGATATACCGCGACTGCGTACGCGCTATGTTGAATGATCCGAAAGCGCTATACACTGCGTCATCGGTCAGTGGTCTGGGG
TTTACCTACCCACCCTTCGCGGCGATCGCCCTCACCCCATTAGCTCTGATTCCGTCTCTGCCGGTAACGATCCTCCACTA
TGGTGTCAGTGCAATCGCTCTTGCCATCATGATTGATCTCATCTGGCGCCGTTGCGGGCACAAGCCTCAGCCATTGCTGA
CGGCCATCTTCGTCGCAGTCTTGAACTTTAGCGAACCCATTGGGAAAACTTTTGTTTATGGACAGGTTAACCTGCAATTA
GCCGCCCTCGTCGTTATTGACGTATTCCTGCTGCCTCGGAGGTGGCGCGGGGTGGGGGTCGGAGTGGCCACCGGATTCAA
GCTCACTCCGGGCATCTTCGCCCTCTGGTATCTCGTCACGGGTCAATTCAAGGCAGCGCTTCGAGCCGCCGCGGCTGGTC
TAGTCACGATCGCCATCGGGCTCGCGGTGATGCCCACAGCATCTTGGGAGTACTGGACCCACTACATGCTCACGCCGAAC
CGTCTGGGTGGGCTCACCTGGGCGGGCAATCAATCACTTTCGGGCATGTTGCTGCGCCTAGGCCATGGCAACCTCACACT
CGTGTGGCTAGTTCTAGTCGCGCTGTGCTGCGCACTTGCCGGTATTGCATCTCGGCGGTTGTGGCAAGAAGGTGGGGCTG
ACCAGGTGTGGTCCCTGTTATGCGCCGGGCTGTGCGGATGCTTGGTGAGTCCCGTGTCATGGTCGCACCACTGGGTATGG
GGGTCCTTAATCATCGTCGCCGGACTAGCCGACCGTCGTCGTTGCCAGCAGGTTCTAGCCCTCATTTGGGCTTTAGCCAC
ACTGACATGGATGGTCTGGTGGTTTCCTGCCGGTCGTAACCGAGAACTCACCGCAGCATGGTGGCAGAAGATCCTGACCG
ACGCCTACGAATTCGTCGGCGTCGCTACCCTTATCGTCCTGCTGTCATCGATGGCTCAACCCACGGATCGGGCTCGCCAG
TGA

Upstream 100 bases:

>100_bases
ATGAGGAAATGGCCACCAAAGCCGACGACTACCAAGCCTTGGTACATCTCCAGACGAAGGCCAACGAACTCGACGCGCGG
ATGACTTCCCTTGAGGAACA

Downstream 100 bases:

>100_bases
TGCGGCTACGCAGGTCACGGCGCACGACCTCGATGCTCCACATCCAGACGATGTGACCCAACAACTCACTGAGATGTTCC
TGCCACGGCTGGTGCCACGG

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-2)-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MARDRRHCGGSVTLQDDSPISGKRPASSLFWPAIAVIMTTVTWTLAMPRPTDLKIYRDCVRAMLNDPKALYTASSVSGLG
FTYPPFAAIALTPLALIPSLPVTILHYGVSAIALAIMIDLIWRRCGHKPQPLLTAIFVAVLNFSEPIGKTFVYGQVNLQL
AALVVIDVFLLPRRWRGVGVGVATGFKLTPGIFALWYLVTGQFKAALRAAAAGLVTIAIGLAVMPTASWEYWTHYMLTPN
RLGGLTWAGNQSLSGMLLRLGHGNLTLVWLVLVALCCALAGIASRRLWQEGGADQVWSLLCAGLCGCLVSPVSWSHHWVW
GSLIIVAGLADRRRCQQVLALIWALATLTWMVWWFPAGRNRELTAAWWQKILTDAYEFVGVATLIVLLSSMAQPTDRARQ

Sequences:

>Translated_400_residues
MARDRRHCGGSVTLQDDSPISGKRPASSLFWPAIAVIMTTVTWTLAMPRPTDLKIYRDCVRAMLNDPKALYTASSVSGLG
FTYPPFAAIALTPLALIPSLPVTILHYGVSAIALAIMIDLIWRRCGHKPQPLLTAIFVAVLNFSEPIGKTFVYGQVNLQL
AALVVIDVFLLPRRWRGVGVGVATGFKLTPGIFALWYLVTGQFKAALRAAAAGLVTIAIGLAVMPTASWEYWTHYMLTPN
RLGGLTWAGNQSLSGMLLRLGHGNLTLVWLVLVALCCALAGIASRRLWQEGGADQVWSLLCAGLCGCLVSPVSWSHHWVW
GSLIIVAGLADRRRCQQVLALIWALATLTWMVWWFPAGRNRELTAAWWQKILTDAYEFVGVATLIVLLSSMAQPTDRARQ
>Mature_399_residues
ARDRRHCGGSVTLQDDSPISGKRPASSLFWPAIAVIMTTVTWTLAMPRPTDLKIYRDCVRAMLNDPKALYTASSVSGLGF
TYPPFAAIALTPLALIPSLPVTILHYGVSAIALAIMIDLIWRRCGHKPQPLLTAIFVAVLNFSEPIGKTFVYGQVNLQLA
ALVVIDVFLLPRRWRGVGVGVATGFKLTPGIFALWYLVTGQFKAALRAAAAGLVTIAIGLAVMPTASWEYWTHYMLTPNR
LGGLTWAGNQSLSGMLLRLGHGNLTLVWLVLVALCCALAGIASRRLWQEGGADQVWSLLCAGLCGCLVSPVSWSHHWVWG
SLIIVAGLADRRRCQQVLALIWALATLTWMVWWFPAGRNRELTAAWWQKILTDAYEFVGVATLIVLLSSMAQPTDRARQ

Specific function: Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 43760; Mature: 43629

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDRRHCGGSVTLQDDSPISGKRPASSLFWPAIAVIMTTVTWTLAMPRPTDLKIYRDCV
CCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
RAMLNDPKALYTASSVSGLGFTYPPFAAIALTPLALIPSLPVTILHYGVSAIALAIMIDL
HHHHCCCHHEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IWRRCGHKPQPLLTAIFVAVLNFSEPIGKTFVYGQVNLQLAALVVIDVFLLPRRWRGVGV
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCHHCCCCE
GVATGFKLTPGIFALWYLVTGQFKAALRAAAAGLVTIAIGLAVMPTASWEYWTHYMLTPN
EHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEECCC
RLGGLTWAGNQSLSGMLLRLGHGNLTLVWLVLVALCCALAGIASRRLWQEGGADQVWSLL
CCCCEEECCCCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CAGLCGCLVSPVSWSHHWVWGSLIIVAGLADRRRCQQVLALIWALATLTWMVWWFPAGRN
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RELTAAWWQKILTDAYEFVGVATLIVLLSSMAQPTDRARQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
ARDRRHCGGSVTLQDDSPISGKRPASSLFWPAIAVIMTTVTWTLAMPRPTDLKIYRDCV
CCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
RAMLNDPKALYTASSVSGLGFTYPPFAAIALTPLALIPSLPVTILHYGVSAIALAIMIDL
HHHHCCCHHEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IWRRCGHKPQPLLTAIFVAVLNFSEPIGKTFVYGQVNLQLAALVVIDVFLLPRRWRGVGV
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCHHCCCCE
GVATGFKLTPGIFALWYLVTGQFKAALRAAAAGLVTIAIGLAVMPTASWEYWTHYMLTPN
EHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEECCC
RLGGLTWAGNQSLSGMLLRLGHGNLTLVWLVLVALCCALAGIASRRLWQEGGADQVWSLL
CCCCEEECCCCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CAGLCGCLVSPVSWSHHWVWGSLIIVAGLADRRRCQQVLALIWALATLTWMVWWFPAGRN
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RELTAAWWQKILTDAYEFVGVATLIVLLSSMAQPTDRARQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]