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The map label for this gene is kdpE [H]

Identifier: 50841610

GI number: 50841610

Start: 144478

End: 145161

Strand: Direct

Name: kdpE [H]

Synonym: PPA0119

Alternate gene names: 50841610

Gene position: 144478-145161 (Clockwise)

Preceding gene: 50841609

Following gene: 50841611

Centisome position: 5.64

GC content: 60.53

Gene sequence:

>684_bases
ATGAGAATTCTTATCGCTGATGACGACCCGCAATTTTTGCGAGCCTTGCGGATCACTTTGGGCGCCAGGGGATACGAGGT
CTTGTTGGCGCGTGATGGGCAGCACGCCTTGGAGATGGCCATCGATCACAAGCCGGACATCATTTTGCTGGATCTCGGGA
TGCCGCGTCTCGACGGGGTAAAGGTCATTGAGGCGGTGCGCGGCTGGTCGTCGGCGCCGATCCTGGTGATCTCGGGACGA
TCCGGGTCGGCCGAGAAGGTGGAAGCCCTTGACGCTGGGGCTGACGACTACGTCACCAAACCATTCTCGATGGATGAGTT
GCTTGCCCGTATCCGCGTGTTGACAAGGCGTATTGGCCAGGACGAGGTAGATGAGGAACCAATCGTCGCTTTCGGGTCGG
TGTGGGTGGATCTGGCTGCGCACACCGTGACCCGTGACGGGGCCAATGTCAGGCTGACGCCGACCGAGTGGCGGGTGCTG
GAGCTGCTCATCCGTAATGAAGGTCGGCTGGTGACTCGTCAGACCATGCTGAGTCAGGTCTGGGGCTCCGAGCACGTCAC
CGACACCGGCTACCTGAGGCTCTACATTTCCCAGTTGCGCAAGAAGCTGGAGCCCGAGCCGAGTAGGCCGCGGTATCTCA
TCACTGATGCCGGAATGGGGTACCGGTTGGTGCTTGACCCCTGA

Upstream 100 bases:

>100_bases
AGGGAATGGACGGCACCCTGGCCTTGGAGGACACTCCCGGCGGGGGACTGACGATGGTGATCAGCTTGCCCCGGGTAGGG
GTTGAGGAGGCAAGTGTTCA

Downstream 100 bases:

>100_bases
TATATGCATATAATAATGCACATGCCCACTAGAAACGTGTATGTCTCCGACGAAGACCAAAACCTGTTCCAAGAAGCAGC
CGAGCTTGCAGGAGGGTTTT

Product: two-component response regulator, KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRILIADDDPQFLRALRITLGARGYEVLLARDGQHALEMAIDHKPDIILLDLGMPRLDGVKVIEAVRGWSSAPILVISGR
SGSAEKVEALDAGADDYVTKPFSMDELLARIRVLTRRIGQDEVDEEPIVAFGSVWVDLAAHTVTRDGANVRLTPTEWRVL
ELLIRNEGRLVTRQTMLSQVWGSEHVTDTGYLRLYISQLRKKLEPEPSRPRYLITDAGMGYRLVLDP

Sequences:

>Translated_227_residues
MRILIADDDPQFLRALRITLGARGYEVLLARDGQHALEMAIDHKPDIILLDLGMPRLDGVKVIEAVRGWSSAPILVISGR
SGSAEKVEALDAGADDYVTKPFSMDELLARIRVLTRRIGQDEVDEEPIVAFGSVWVDLAAHTVTRDGANVRLTPTEWRVL
ELLIRNEGRLVTRQTMLSQVWGSEHVTDTGYLRLYISQLRKKLEPEPSRPRYLITDAGMGYRLVLDP
>Mature_227_residues
MRILIADDDPQFLRALRITLGARGYEVLLARDGQHALEMAIDHKPDIILLDLGMPRLDGVKVIEAVRGWSSAPILVISGR
SGSAEKVEALDAGADDYVTKPFSMDELLARIRVLTRRIGQDEVDEEPIVAFGSVWVDLAAHTVTRDGANVRLTPTEWRVL
ELLIRNEGRLVTRQTMLSQVWGSEHVTDTGYLRLYISQLRKKLEPEPSRPRYLITDAGMGYRLVLDP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=45.2914798206278, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=32.7433628318584, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=32.5892857142857, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=29.9107142857143, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=30.6666666666667, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=29.5652173913043, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=30.1801801801802, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=30.3964757709251, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=32.4561403508772, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=29.2576419213974, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=29.8245614035088, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=27.3913043478261, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=28.8288288288288, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=38.3177570093458, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=35.4545454545455, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=119, Percent_Identity=30.2521008403361, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=23.6842105263158, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=35.6435643564356, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25466; Mature: 25466

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIADDDPQFLRALRITLGARGYEVLLARDGQHALEMAIDHKPDIILLDLGMPRLDGV
CEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCCEEEEECCCCCCCHH
KVIEAVRGWSSAPILVISGRSGSAEKVEALDAGADDYVTKPFSMDELLARIRVLTRRIGQ
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
DEVDEEPIVAFGSVWVDLAAHTVTRDGANVRLTPTEWRVLELLIRNEGRLVTRQTMLSQV
CCCCCCCEEEHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHCCCCEEHHHHHHHHH
WGSEHVTDTGYLRLYISQLRKKLEPEPSRPRYLITDAGMGYRLVLDP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECC
>Mature Secondary Structure
MRILIADDDPQFLRALRITLGARGYEVLLARDGQHALEMAIDHKPDIILLDLGMPRLDGV
CEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCCEEEEECCCCCCCHH
KVIEAVRGWSSAPILVISGRSGSAEKVEALDAGADDYVTKPFSMDELLARIRVLTRRIGQ
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
DEVDEEPIVAFGSVWVDLAAHTVTRDGANVRLTPTEWRVLELLIRNEGRLVTRQTMLSQV
CCCCCCCEEEHHHHHHHHHHHHEECCCCEEEECCCHHHHHHHHHHCCCCEEHHHHHHHHH
WGSEHVTDTGYLRLYISQLRKKLEPEPSRPRYLITDAGMGYRLVLDP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]