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The map label for this gene is kdpD [H]

Identifier: 50841609

GI number: 50841609

Start: 141989

End: 144481

Strand: Direct

Name: kdpD [H]

Synonym: PPA0118

Alternate gene names: 50841609

Gene position: 141989-144481 (Clockwise)

Preceding gene: 50841608

Following gene: 50841610

Centisome position: 5.55

GC content: 64.26

Gene sequence:

>2493_bases
GTGGCTGTTCGGGGAAGGTTGCGGGTGCTGCTGGGCGCGGCACCGGGCGTCGGCAAGACCTACGCCATGCTTGACGAGGG
CAAGCACCTGCGCGCCGGGGGGTCTGATGTCGTTATCGCCGTTGTTGAGACTCACGGCCGGGCAGCTACTGCGGCAATGA
CCGAGGGGATGGAGGTCATCCCGCGGCACTACGTCGAGTGCCGTGGCATTGAGCTGCCGGAGATGGATCTTGACGGGGTG
CTGGCCCAGCACCCTGACGTCGCCCTCGTCGACGAACTTGCCCACACCAACGCCCCCGGGTCCCGTAATGAGAAGCGTTG
GCAGGACGTTGAGGAGCTTCTGGAGGCCGGGATTGACGTCATCTCGACGGTCAACATCCAGCACATCGAGTCTCTCAACG
ACGTCGTTGAGCAAATCACTGGGGTACCACAGCGCGAGACTGTCCCGGACACCGTGCTGCGCAGGGCCAGCCAGGTGGAG
GTCGTCGACCTCGCCCCGCAGGCCCTGCGCGACCGATTGTCGAGCGGCAAGGTGTATCCGGCCGAGCGGATCGACGCGGC
CTTGTCAAACTACTTCCGGCTCGGCAATCTCACCGCCCTGCGTGAGTTGGCCTTGTTGTGGGTGGCCGACGAGGTCGATC
ACGCGCTGGCCGACTACCGTAGCGAGCACGGTATCGACTCCCGTTGGGAAGCCCGTGAACGGGTAGTCGTCGCCCTGACA
GGGGGTCGGGAAGGCGAAACCCTGTTGCGACGCGGTGCCCGGATCGCGGTTCGAGCCGGTGGCGGAGAGTTGCTGGCGGT
GCACGTCACCACCGAGGACGGGCTGCGCTCCCCGCATCCGGGGGAACTAGCCCGGCAACGAGGGTTGGTGGACAAGCTAG
GAGGATCCTTCCACCAGCTCGTTGGCGATGACATCCCCGAGACTCTCATCGAGTTCGCGAAGTCGGTCAACGCCACCCAG
CTCGTCATCGGGGCTAGTCGGCGCGGCAAACTTTCGCGGCTGTTGACCGGACACGACGTCGAGGCAGACATTATCCGGGC
TTCCGGTGCTATCGACGTTCACATCGTCAGTCATGACGCCCAGGCGAAGGCGCTGCGTTTGCCGCGGATGGGTGGGTCGT
TGTCGACGCGGCGTCGGATCGCTGGTTTCGCTGTGCTGGCGGTGCTCGGGCCACTCTTGACGTTGCTGTTGGTGTCGTCG
CGTAGCCCGGAGGCGCTGACGACCGATGTGCTGGCTTACGAGTTGCTGGCCGTCGTGGTGGCCTTGGTAGGTGGGGCATT
TTCGTCGCTCATTGCGGCTCTGGCCTCGGGTTTTGCGCTGGACTATTTTTTCACTAAACCTTTCTACACCGTCACCGTCA
ACGAACCGTTACACCTGGTGGCACTGTTGCTGTACCTGCTCACCGCGGCCCTGGTGAGTGTTGTTGTCGATCGCGCTGCC
CGTAAGACCAGGGTGGCTCGACGCGCCGCCGCTGAGTCGGGACTGTTGCAGTCGGTGGCCGGTTTGGTGCTGCGCGGCGA
GGACGCCGTTGAGTCGTTGTTGTCCAGGGCGACTGAGGCTTTCGGGTTATCTGGGGCGCGATTGATGACCGACGGAAAGG
TTGTGGCAAATTGGGGTACAACGAGTGATCAAGTCACGGAGCATCGCATCGACGACCATACCGTGGTGGAATTCCACGGC
CCGGAGCCGGACGCCTCGGAGCGTCGGCTGATGTCGGTCATCGCCGCCCAGTTGGGGACAGCCTTGGAGCAGCATCAGCT
GGAGGAGACGGCGAAGGCGGTGGAGCCGTTAGCGGCCACCGACCGGGTGCGCACGGCGTTGTTGTCAGCGGTCGGTCACG
ACCTGCGCCGCCCCCTGGCGGCTGCCACCGCCGCTGTGTCTGGGCTGCGCAGCGAGTGGTCGAAGCTTTCTGACCAAGAT
CGTGCCGATTTGTTGGAAACCGCTGATGAGGCGTTGTCGCAGTTGGCGAATTTGGTCACCGACCTTCTCGACGTCTCCCG
GTTGCAGTCGGGGGTGCTGGGGGTCTCGGTGATGCCGGTAGACCCGGCTGAGGTCATCATGCCGGCGCTGGACGAGTTGT
CCCTGGGGCCGGCCGACGTCGAGATCGACCTGGGTTCTGACGTTCCCGAGATGGTCGCCGACCCAGCCTTGCTGCAGCGA
GTTGTCGTCAACCTGTTGTCGAATGCGCTGCGTTACGAGCCGGCGGGCAGCCGGGTGCGGTTGGCGGAGAGTAGCTTCGC
CAACCAGGTGGAGATTCGAGTCATCGATCACGGCCCGGGGATTCCAGAGGACCGTCGCGACGATGTCATGGTGCCTTTCC
AGCGGCTGGGTGATACGGATTCCAGCGTAGGGCTGGGGCTTGGCCTGGCGCTGTCGAAGGGGTTCGTCGAGGGAATGGAC
GGCACCCTGGCCTTGGAGGACACTCCCGGCGGGGGACTGACGATGGTGATCAGCTTGCCCCGGGTAGGGGTTGAGGAGGC
AAGTGTTCAATGA

Upstream 100 bases:

>100_bases
CTCGGTGAGACTAAGGTCAACGTCGTGACGCTCAATGCCGAACTGGATCGCCAGCACTGACGGTGCTGACGGTCGGGTAA
TCATGGCCTAGGAGGACGCG

Downstream 100 bases:

>100_bases
GAATTCTTATCGCTGATGACGACCCGCAATTTTTGCGAGCCTTGCGGATCACTTTGGGCGCCAGGGGATACGAGGTCTTG
TTGGCGCGTGATGGGCAGCA

Product: two-component sensor, KdpD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 830; Mature: 829

Protein sequence:

>830_residues
MAVRGRLRVLLGAAPGVGKTYAMLDEGKHLRAGGSDVVIAVVETHGRAATAAMTEGMEVIPRHYVECRGIELPEMDLDGV
LAQHPDVALVDELAHTNAPGSRNEKRWQDVEELLEAGIDVISTVNIQHIESLNDVVEQITGVPQRETVPDTVLRRASQVE
VVDLAPQALRDRLSSGKVYPAERIDAALSNYFRLGNLTALRELALLWVADEVDHALADYRSEHGIDSRWEARERVVVALT
GGREGETLLRRGARIAVRAGGGELLAVHVTTEDGLRSPHPGELARQRGLVDKLGGSFHQLVGDDIPETLIEFAKSVNATQ
LVIGASRRGKLSRLLTGHDVEADIIRASGAIDVHIVSHDAQAKALRLPRMGGSLSTRRRIAGFAVLAVLGPLLTLLLVSS
RSPEALTTDVLAYELLAVVVALVGGAFSSLIAALASGFALDYFFTKPFYTVTVNEPLHLVALLLYLLTAALVSVVVDRAA
RKTRVARRAAAESGLLQSVAGLVLRGEDAVESLLSRATEAFGLSGARLMTDGKVVANWGTTSDQVTEHRIDDHTVVEFHG
PEPDASERRLMSVIAAQLGTALEQHQLEETAKAVEPLAATDRVRTALLSAVGHDLRRPLAAATAAVSGLRSEWSKLSDQD
RADLLETADEALSQLANLVTDLLDVSRLQSGVLGVSVMPVDPAEVIMPALDELSLGPADVEIDLGSDVPEMVADPALLQR
VVVNLLSNALRYEPAGSRVRLAESSFANQVEIRVIDHGPGIPEDRRDDVMVPFQRLGDTDSSVGLGLGLALSKGFVEGMD
GTLALEDTPGGGLTMVISLPRVGVEEASVQ

Sequences:

>Translated_830_residues
MAVRGRLRVLLGAAPGVGKTYAMLDEGKHLRAGGSDVVIAVVETHGRAATAAMTEGMEVIPRHYVECRGIELPEMDLDGV
LAQHPDVALVDELAHTNAPGSRNEKRWQDVEELLEAGIDVISTVNIQHIESLNDVVEQITGVPQRETVPDTVLRRASQVE
VVDLAPQALRDRLSSGKVYPAERIDAALSNYFRLGNLTALRELALLWVADEVDHALADYRSEHGIDSRWEARERVVVALT
GGREGETLLRRGARIAVRAGGGELLAVHVTTEDGLRSPHPGELARQRGLVDKLGGSFHQLVGDDIPETLIEFAKSVNATQ
LVIGASRRGKLSRLLTGHDVEADIIRASGAIDVHIVSHDAQAKALRLPRMGGSLSTRRRIAGFAVLAVLGPLLTLLLVSS
RSPEALTTDVLAYELLAVVVALVGGAFSSLIAALASGFALDYFFTKPFYTVTVNEPLHLVALLLYLLTAALVSVVVDRAA
RKTRVARRAAAESGLLQSVAGLVLRGEDAVESLLSRATEAFGLSGARLMTDGKVVANWGTTSDQVTEHRIDDHTVVEFHG
PEPDASERRLMSVIAAQLGTALEQHQLEETAKAVEPLAATDRVRTALLSAVGHDLRRPLAAATAAVSGLRSEWSKLSDQD
RADLLETADEALSQLANLVTDLLDVSRLQSGVLGVSVMPVDPAEVIMPALDELSLGPADVEIDLGSDVPEMVADPALLQR
VVVNLLSNALRYEPAGSRVRLAESSFANQVEIRVIDHGPGIPEDRRDDVMVPFQRLGDTDSSVGLGLGLALSKGFVEGMD
GTLALEDTPGGGLTMVISLPRVGVEEASVQ
>Mature_829_residues
AVRGRLRVLLGAAPGVGKTYAMLDEGKHLRAGGSDVVIAVVETHGRAATAAMTEGMEVIPRHYVECRGIELPEMDLDGVL
AQHPDVALVDELAHTNAPGSRNEKRWQDVEELLEAGIDVISTVNIQHIESLNDVVEQITGVPQRETVPDTVLRRASQVEV
VDLAPQALRDRLSSGKVYPAERIDAALSNYFRLGNLTALRELALLWVADEVDHALADYRSEHGIDSRWEARERVVVALTG
GREGETLLRRGARIAVRAGGGELLAVHVTTEDGLRSPHPGELARQRGLVDKLGGSFHQLVGDDIPETLIEFAKSVNATQL
VIGASRRGKLSRLLTGHDVEADIIRASGAIDVHIVSHDAQAKALRLPRMGGSLSTRRRIAGFAVLAVLGPLLTLLLVSSR
SPEALTTDVLAYELLAVVVALVGGAFSSLIAALASGFALDYFFTKPFYTVTVNEPLHLVALLLYLLTAALVSVVVDRAAR
KTRVARRAAAESGLLQSVAGLVLRGEDAVESLLSRATEAFGLSGARLMTDGKVVANWGTTSDQVTEHRIDDHTVVEFHGP
EPDASERRLMSVIAAQLGTALEQHQLEETAKAVEPLAATDRVRTALLSAVGHDLRRPLAAATAAVSGLRSEWSKLSDQDR
ADLLETADEALSQLANLVTDLLDVSRLQSGVLGVSVMPVDPAEVIMPALDELSLGPADVEIDLGSDVPEMVADPALLQRV
VVNLLSNALRYEPAGSRVRLAESSFANQVEIRVIDHGPGIPEDRRDDVMVPFQRLGDTDSSVGLGLGLALSKGFVEGMDG
TLALEDTPGGGLTMVISLPRVGVEEASVQ

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=868, Percent_Identity=31.7972350230415, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=28.8537549407115, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=27.3092369477912, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=24.8, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=227, Percent_Identity=29.5154185022026, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=27.6785714285714, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=241, Percent_Identity=28.6307053941909, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=26.271186440678, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787894, Length=248, Percent_Identity=27.8225806451613, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=29.004329004329, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=26.8181818181818, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852 [H]

Pfam domain/function: PF02518 HATPase_c; PF02702 KdpD [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88619; Mature: 88488

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRGRLRVLLGAAPGVGKTYAMLDEGKHLRAGGSDVVIAVVETHGRAATAAMTEGMEVI
CCCCCCEEEEEECCCCCCCCHHHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHCCHHHH
PRHYVECRGIELPEMDLDGVLAQHPDVALVDELAHTNAPGSRNEKRWQDVEELLEAGIDV
HHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH
ISTVNIQHIESLNDVVEQITGVPQRETVPDTVLRRASQVEVVDLAPQALRDRLSSGKVYP
HHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCC
AERIDAALSNYFRLGNLTALRELALLWVADEVDHALADYRSEHGIDSRWEARERVVVALT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEEE
GGREGETLLRRGARIAVRAGGGELLAVHVTTEDGLRSPHPGELARQRGLVDKLGGSFHQL
CCCCCHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCHHHHCCHHHHH
VGDDIPETLIEFAKSVNATQLVIGASRRGKLSRLLTGHDVEADIIRASGAIDVHIVSHDA
HCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCCHHHEEECCCEEEEEECCCC
QAKALRLPRMGGSLSTRRRIAGFAVLAVLGPLLTLLLVSSRSPEALTTDVLAYELLAVVV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ALVGGAFSSLIAALASGFALDYFFTKPFYTVTVNEPLHLVALLLYLLTAALVSVVVDRAA
HHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RKTRVARRAAAESGLLQSVAGLVLRGEDAVESLLSRATEAFGLSGARLMTDGKVVANWGT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCC
TSDQVTEHRIDDHTVVEFHGPEPDASERRLMSVIAAQLGTALEQHQLEETAKAVEPLAAT
CCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRVRTALLSAVGHDLRRPLAAATAAVSGLRSEWSKLSDQDRADLLETADEALSQLANLVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DLLDVSRLQSGVLGVSVMPVDPAEVIMPALDELSLGPADVEIDLGSDVPEMVADPALLQR
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHCCHHHHHH
VVVNLLSNALRYEPAGSRVRLAESSFANQVEIRVIDHGPGIPEDRRDDVMVPFQRLGDTD
HHHHHHHHHHHCCCCCCEEEEEHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCC
SSVGLGLGLALSKGFVEGMDGTLALEDTPGGGLTMVISLPRVGVEEASVQ
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
AVRGRLRVLLGAAPGVGKTYAMLDEGKHLRAGGSDVVIAVVETHGRAATAAMTEGMEVI
CCCCCEEEEEECCCCCCCCHHHHCCCCEEECCCCCEEEEEEECCCCHHHHHHHCCHHHH
PRHYVECRGIELPEMDLDGVLAQHPDVALVDELAHTNAPGSRNEKRWQDVEELLEAGIDV
HHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH
ISTVNIQHIESLNDVVEQITGVPQRETVPDTVLRRASQVEVVDLAPQALRDRLSSGKVYP
HHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEECCCHHHHHHHHHCCCCCC
AERIDAALSNYFRLGNLTALRELALLWVADEVDHALADYRSEHGIDSRWEARERVVVALT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEEEE
GGREGETLLRRGARIAVRAGGGELLAVHVTTEDGLRSPHPGELARQRGLVDKLGGSFHQL
CCCCCHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHCCCHHHHCCHHHHH
VGDDIPETLIEFAKSVNATQLVIGASRRGKLSRLLTGHDVEADIIRASGAIDVHIVSHDA
HCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCCHHHEEECCCEEEEEECCCC
QAKALRLPRMGGSLSTRRRIAGFAVLAVLGPLLTLLLVSSRSPEALTTDVLAYELLAVVV
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ALVGGAFSSLIAALASGFALDYFFTKPFYTVTVNEPLHLVALLLYLLTAALVSVVVDRAA
HHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RKTRVARRAAAESGLLQSVAGLVLRGEDAVESLLSRATEAFGLSGARLMTDGKVVANWGT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCC
TSDQVTEHRIDDHTVVEFHGPEPDASERRLMSVIAAQLGTALEQHQLEETAKAVEPLAAT
CCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRVRTALLSAVGHDLRRPLAAATAAVSGLRSEWSKLSDQDRADLLETADEALSQLANLVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DLLDVSRLQSGVLGVSVMPVDPAEVIMPALDELSLGPADVEIDLGSDVPEMVADPALLQR
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHCCHHHHHH
VVVNLLSNALRYEPAGSRVRLAESSFANQVEIRVIDHGPGIPEDRRDDVMVPFQRLGDTD
HHHHHHHHHHHCCCCCCEEEEEHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHCCCCC
SSVGLGLGLALSKGFVEGMDGTLALEDTPGGGLTMVISLPRVGVEEASVQ
CCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA