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The map label for this gene is exoB [H]

Identifier: 50841560

GI number: 50841560

Start: 71871

End: 72860

Strand: Direct

Name: exoB [H]

Synonym: PPA0069

Alternate gene names: 50841560

Gene position: 71871-72860 (Clockwise)

Preceding gene: 50841558

Following gene: 50841562

Centisome position: 2.81

GC content: 59.09

Gene sequence:

>990_bases
ATGAAGATTCTCATCACCGGCGGGGCCGGTTACATCGGATCAACGGTTGGTTCGGCATGTGAGGAGGCCGGCCATGAGGT
CGTCGTGCTGGACGACCTATCCGCGGGACGCCGCGAATTCGTTCGCGACCGCACGTTCTACGAGGGCGACATCGCTGATC
AGGACCTGCTCGATCGCGTCTTCTCCGAGAACCAGATCGACGCCGTCGTCCACTGCGCAGCCAAGATCATCGTCCCCGAA
TCGGTTGATGAGCCGCTGACCTATTACGGCAACAATGTCGGCAAGACCGTTGCTCTGCTCAAGGGAATGGAGCGCAACGG
CGTACACCGCATCTTGTTTTCGTCCTCGGCGTCGATCTATGCCACTGACGAGGAGTTCAAGGTCACTGAGGAATCCGCTC
TGGACCCCGGTTCCCCCTATGCCACCACCAAGTTCATGGTGGAGTTCATCTTGCGTGACGCCGCGCACGCCTCTGATCTC
AAGGCATTGAGCCTGCGGTACTTTAACCCGATCGGTTCAGACCCGAAGCTGCGTACTGGTCAGCAGATTGAGCATCCCAC
CCACGTGCTCGGCAAGATGATTGACGCCTGGATGGAGGGTTCCACTTTCACCGTCACTGGAGTGGACTGGCCGACTCGTG
ATGGGTCAGGTATTCGCGACTACATCCACGTTTGGGATCTGGCTCGCGCTCATGTTGCTGCTTTGGAGCATCTCGATGAG
GTTACGACCGACGACCCGTACCAGGTATTCAATATCGGTACCGGAAGCGGCGTTACCGTTAAGGAGCTCGTTAAGGCCTT
CGAAGAGGGTACGGGTAAATCCCTCAATGTCGTCTACGGCCCGCCGCGTCCCGGCGATGTCGCAGGTGCCTACACGGTGT
CCCGCCGGGCCAAAGACCTGCTCGGTTGGAGCGCGGAGCTGACCCAGGCGGATGGAATCCGTGACGCCATTGCATGGTTG
CCCGAGCGCAAGAAGATCCTGGGTTACTGA

Upstream 100 bases:

>100_bases
TTCGTGACCAATTCACCACACGCAGCCCGTGCCCGCCATCGAGGCTGGCGAGCCGCACCTAGACTTGACGGCGACGAGAT
CGACGTTACGGAAGGTTCCC

Downstream 100 bases:

>100_bases
TTCTTCCCTGTTGCCACACCACCGGCCCTGCACTTGTGCGGGGCCGGTGCTATGTCGGGGCCTGTCGCGGGATCACATGG
GGTGGACGAAGGTCAGCACC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKILITGGAGYIGSTVGSACEEAGHEVVVLDDLSAGRREFVRDRTFYEGDIADQDLLDRVFSENQIDAVVHCAAKIIVPE
SVDEPLTYYGNNVGKTVALLKGMERNGVHRILFSSSASIYATDEEFKVTEESALDPGSPYATTKFMVEFILRDAAHASDL
KALSLRYFNPIGSDPKLRTGQQIEHPTHVLGKMIDAWMEGSTFTVTGVDWPTRDGSGIRDYIHVWDLARAHVAALEHLDE
VTTDDPYQVFNIGTGSGVTVKELVKAFEEGTGKSLNVVYGPPRPGDVAGAYTVSRRAKDLLGWSAELTQADGIRDAIAWL
PERKKILGY

Sequences:

>Translated_329_residues
MKILITGGAGYIGSTVGSACEEAGHEVVVLDDLSAGRREFVRDRTFYEGDIADQDLLDRVFSENQIDAVVHCAAKIIVPE
SVDEPLTYYGNNVGKTVALLKGMERNGVHRILFSSSASIYATDEEFKVTEESALDPGSPYATTKFMVEFILRDAAHASDL
KALSLRYFNPIGSDPKLRTGQQIEHPTHVLGKMIDAWMEGSTFTVTGVDWPTRDGSGIRDYIHVWDLARAHVAALEHLDE
VTTDDPYQVFNIGTGSGVTVKELVKAFEEGTGKSLNVVYGPPRPGDVAGAYTVSRRAKDLLGWSAELTQADGIRDAIAWL
PERKKILGY
>Mature_329_residues
MKILITGGAGYIGSTVGSACEEAGHEVVVLDDLSAGRREFVRDRTFYEGDIADQDLLDRVFSENQIDAVVHCAAKIIVPE
SVDEPLTYYGNNVGKTVALLKGMERNGVHRILFSSSASIYATDEEFKVTEESALDPGSPYATTKFMVEFILRDAAHASDL
KALSLRYFNPIGSDPKLRTGQQIEHPTHVLGKMIDAWMEGSTFTVTGVDWPTRDGSGIRDYIHVWDLARAHVAALEHLDE
VTTDDPYQVFNIGTGSGVTVKELVKAFEEGTGKSLNVVYGPPRPGDVAGAYTVSRRAKDLLGWSAELTQADGIRDAIAWL
PERKKILGY

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=35.3623188405797, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=35.3623188405797, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=35.3623188405797, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI7657641, Length=340, Percent_Identity=24.4117647058824, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI42516563, Length=325, Percent_Identity=23.3846153846154, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=35.8433734939759, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI48994969, Length=352, Percent_Identity=28.4090909090909, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788353, Length=360, Percent_Identity=26.1111111111111, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788365, Length=337, Percent_Identity=23.4421364985163, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=35.3623188405797, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=35.1585014409222, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI115532424, Length=349, Percent_Identity=24.9283667621776, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568069, Length=343, Percent_Identity=25.6559766763848, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=326, Percent_Identity=21.1656441717791, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=339, Percent_Identity=38.3480825958702, Blast_Score=195, Evalue=9e-51,
Organism=Drosophila melanogaster, GI19923002, Length=335, Percent_Identity=38.5074626865672, Blast_Score=197, Evalue=7e-51,
Organism=Drosophila melanogaster, GI21356223, Length=325, Percent_Identity=22.4615384615385, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35983; Mature: 35983

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILITGGAGYIGSTVGSACEEAGHEVVVLDDLSAGRREFVRDRTFYEGDIADQDLLDRV
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHH
FSENQIDAVVHCAAKIIVPESVDEPLTYYGNNVGKTVALLKGMERNGVHRILFSSSASIY
HCCCCHHHHHHHHHHEECCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCCEEE
ATDEEFKVTEESALDPGSPYATTKFMVEFILRDAAHASDLKALSLRYFNPIGSDPKLRTG
ECCCCCEECHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
QQIEHPTHVLGKMIDAWMEGSTFTVTGVDWPTRDGSGIRDYIHVWDLARAHVAALEHLDE
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VTTDDPYQVFNIGTGSGVTVKELVKAFEEGTGKSLNVVYGPPRPGDVAGAYTVSRRAKDL
HCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
LGWSAELTQADGIRDAIAWLPERKKILGY
HCCCHHHHHCCCHHHHHHHCCCCHHHCCC
>Mature Secondary Structure
MKILITGGAGYIGSTVGSACEEAGHEVVVLDDLSAGRREFVRDRTFYEGDIADQDLLDRV
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHH
FSENQIDAVVHCAAKIIVPESVDEPLTYYGNNVGKTVALLKGMERNGVHRILFSSSASIY
HCCCCHHHHHHHHHHEECCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCCEEE
ATDEEFKVTEESALDPGSPYATTKFMVEFILRDAAHASDLKALSLRYFNPIGSDPKLRTG
ECCCCCEECHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
QQIEHPTHVLGKMIDAWMEGSTFTVTGVDWPTRDGSGIRDYIHVWDLARAHVAALEHLDE
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VTTDDPYQVFNIGTGSGVTVKELVKAFEEGTGKSLNVVYGPPRPGDVAGAYTVSRRAKDL
HCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
LGWSAELTQADGIRDAIAWLPERKKILGY
HCCCHHHHHCCCHHHHHHHCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]