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The map label for this gene is rbsK [H]

Identifier: 50365457

GI number: 50365457

Start: 747090

End: 748016

Strand: Reverse

Name: rbsK [H]

Synonym: Mfl642

Alternate gene names: 50365457

Gene position: 748016-747090 (Counterclockwise)

Preceding gene: 50365458

Following gene: 50365455

Centisome position: 94.3

GC content: 28.05

Gene sequence:

>927_bases
ATGAAAAAAATACTAACTATGGGATCTATCGGTGTTGACCATGTATTTAATGTAGATAAATTGCCAAATAAAGGGCAAAG
CATTATTTCAAAAAACTTTAATATATTTTTTGGAGGAAAAGGCGCAAATCAAGCTGTTGCAGCAGCCAAATTAGGTGCGG
ATGTTAAATATATAGGACACGTAGGAAATGATGATGCAGGTTTACATGCAATTGAAAATTTAGTAAAAAATAAAATTGAT
GCATCATATATTAAAAAAATTAATAATATAAATACACAAGTAGCTAATATTATTGTTGATGATAAAGGTGATAATTTACT
AATTGTTGATACAGGTGCTAACTTTACATTTTTAAAAGATGAAATTAATGAATATAAAGAGCTTATTGACCATTCAGATA
TTTTGCTTACCCAGCTAGAAACAAATTTAGAATTTGTAGAAGATTTTATTAATTATGGACATTCTAAAAATAAATTAATT
ATTTTAAACCCAGGTCCAGCAAAAGTAATTTCAAATAAAATTATTGAAAAATGTGATTTTATTACACCTAATGAATCAGA
AATATGTATTTTATTAGGTAAAGAATACACTGAAAACTATGAGTTATTGAAAAAGTATGCATATGAATTATGAGACATCA
ATAAAAAAAATGTTATTGTCACTCTTGGAGAAAATGGTTCTATTTGAATTGATGAAAAAGGTGAACTGCACAAGTTTGAA
GCATATAAAGTAAAAGCTGTTGATGCAACGGCTTGCGGAGATACTTTTATGGGTGGGATATCTGCATACTTAGCTCAAGA
TAAAACTATTGAAGAAGCAATTAAATTTGCCACTGCAGCAGCTTCATTAGCAGTAACAAAAATGGGAGCGCAATCTTCAT
TACCTGAACTTAAAGAAGTTCATGAATTTATTAAAAAAAATGGTTAA

Upstream 100 bases:

>100_bases
AAAGATAAAATTAAAAGACCAGAATTATATGTAAAACAAAAAACAACTAAAAAATCAACAATTAAAGAAGAAAAATCAAA
TTAGAAAAGGAAAAATTAAA

Downstream 100 bases:

>100_bases
GAGTTTCAACCCTTAACCATTGTATTAGACTTAGTTAAAATATCTGAAGTTCCATCTTTATTATTTATAACAATATTAAA
AAGTAAGTTTGAAATAAAAA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKKILTMGSIGVDHVFNVDKLPNKGQSIISKNFNIFFGGKGANQAVAAAKLGADVKYIGHVGNDDAGLHAIENLVKNKID
ASYIKKINNINTQVANIIVDDKGDNLLIVDTGANFTFLKDEINEYKELIDHSDILLTQLETNLEFVEDFINYGHSKNKLI
ILNPGPAKVISNKIIEKCDFITPNESEICILLGKEYTENYELLKKYAYELWDINKKNVIVTLGENGSIWIDEKGELHKFE
AYKVKAVDATACGDTFMGGISAYLAQDKTIEEAIKFATAAASLAVTKMGAQSSLPELKEVHEFIKKNG

Sequences:

>Translated_308_residues
MKKILTMGSIGVDHVFNVDKLPNKGQSIISKNFNIFFGGKGANQAVAAAKLGADVKYIGHVGNDDAGLHAIENLVKNKID
ASYIKKINNINTQVANIIVDDKGDNLLIVDTGANFTFLKDEINEYKELIDHSDILLTQLETNLEFVEDFINYGHSKNKLI
ILNPGPAKVISNKIIEKCDFITPNESEICILLGKEYTENYELLKKYAYEL*DINKKNVIVTLGENGSI*IDEKGELHKFE
AYKVKAVDATACGDTFMGGISAYLAQDKTIEEAIKFATAAASLAVTKMGAQSSLPELKEVHEFIKKNG
>Mature_308_residues
MKKILTMGSIGVDHVFNVDKLPNKGQSIISKNFNIFFGGKGANQAVAAAKLGADVKYIGHVGNDDAGLHAIENLVKNKID
ASYIKKINNINTQVANIIVDDKGDNLLIVDTGANFTFLKDEINEYKELIDHSDILLTQLETNLEFVEDFINYGHSKNKLI
ILNPGPAKVISNKIIEKCDFITPNESEICILLGKEYTENYELLKKYAYEL*DINKKNVIVTLGENGSI*IDEKGELHKFE
AYKVKAVDATACGDTFMGGISAYLAQDKTIEEAIKFATAAASLAVTKMGAQSSLPELKEVHEFIKKNG

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=30.7432432432432, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=35.5263157894737, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI87082343, Length=308, Percent_Identity=25.974025974026, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081971, Length=304, Percent_Identity=23.0263157894737, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789432, Length=261, Percent_Identity=24.904214559387, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=302, Percent_Identity=33.4437086092715, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=30.5135951661631, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=30.8970099667774, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=27.6666666666667, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33582; Mature: 33582

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILTMGSIGVDHVFNVDKLPNKGQSIISKNFNIFFGGKGANQAVAAAKLGADVKYIGH
CCCEEECCCCCHHHEECCCCCCCCCHHHHHCCCEEEECCCCCCHHHHHHHHCCCEEEEEC
VGNDDAGLHAIENLVKNKIDASYIKKINNINTQVANIIVDDKGDNLLIVDTGANFTFLKD
CCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCEEEHHH
EINEYKELIDHSDILLTQLETNLEFVEDFINYGHSKNKLIILNPGPAKVISNKIIEKCDF
HHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCC
ITPNESEICILLGKEYTENYELLKKYAYELDINKKNVIVTLGENGSIIDEKGELHKFEAY
CCCCCCCEEEEECCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCCEECCCCCEEEEEEE
KVKAVDATACGDTFMGGISAYLAQDKTIEEAIKFATAAASLAVTKMGAQSSLPELKEVHE
EEEEECCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FIKKNG
HHHCCC
>Mature Secondary Structure
MKKILTMGSIGVDHVFNVDKLPNKGQSIISKNFNIFFGGKGANQAVAAAKLGADVKYIGH
CCCEEECCCCCHHHEECCCCCCCCCHHHHHCCCEEEECCCCCCHHHHHHHHCCCEEEEEC
VGNDDAGLHAIENLVKNKIDASYIKKINNINTQVANIIVDDKGDNLLIVDTGANFTFLKD
CCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCCEEEHHH
EINEYKELIDHSDILLTQLETNLEFVEDFINYGHSKNKLIILNPGPAKVISNKIIEKCDF
HHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCC
ITPNESEICILLGKEYTENYELLKKYAYELDINKKNVIVTLGENGSIIDEKGELHKFEAY
CCCCCCCEEEEECCCCCCHHHHHHHHHHHEECCCCEEEEEECCCCCEECCCCCEEEEEEE
KVKAVDATACGDTFMGGISAYLAQDKTIEEAIKFATAAASLAVTKMGAQSSLPELKEVHE
EEEEECCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FIKKNG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]