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The map label for this gene is rpe [H]

Identifier: 50365455

GI number: 50365455

Start: 745535

End: 746218

Strand: Reverse

Name: rpe [H]

Synonym: Mfl640

Alternate gene names: 50365455

Gene position: 746218-745535 (Counterclockwise)

Preceding gene: 50365457

Following gene: 50365454

Centisome position: 94.07

GC content: 25.29

Gene sequence:

>684_bases
ATGAATAATAAAAAAGTAGCCGTAAGCATTTATGTATTTAATTTTCTAGAAATAGGAAAAAAAATAGATGAATTAATAGA
AGCAGGCATGGAATGAATTCATGTAGACATAATGGACGGAAATTTTGTTAATAATTATGCTTTATGCCAAAAATTTTGTA
AAGATATCAAAGACAAATATCCTAAAATAAAAGTAGACGCGCATATGATGTGCTCAAATAGCGAAAAATATATTGAGTCA
TTTGCTGAGGCGGGATGTGACTACTTTATATTCCATTATGAAACATTAACAGATAAAAACCCAATAACTGTTAATAATAT
AATAAATAAAATTAAAAGCTATAATATGAAACCTATAATTGCTTTAAATCCAGAAACTAGTTTTGAGCATATCAAAACTT
ATTGTGATGATCTTTATGCAGTAATGTGTATGAATATACTTCCTGGATTTAATGGGCAAAAAATTATAGAATCTTCGTAT
TCTAAAATTAATATAATAAATAAATATAGAAAAGAAAATAATAAAGTATTTAAAATTATGACTGATGGTGGATTAAGAGA
AGACACATATAAAGAAATCTTAGATGCAGGAGCTGACATTGTTGTGGTAGGAGCTTTTGTAAACGTAGAAAATAATAAAT
TAAAAGGGCAATTTGAAAAAATTAAAAATTATGAAATTAAATAA

Upstream 100 bases:

>100_bases
TCAAGTGCTGACATTTCAGCAAAAGTAAGATTTTTACTCATATAAAACACCTCAATTTAGAATATCTTAATTAATTATAT
AAAATAAAAAGGAGAAAAAA

Downstream 100 bases:

>100_bases
TTATATAGATGCAACTCTTTTAAAACCTGATGCAACTTTAATTGAAATTAATAAGTTTGTTGATTTATGTATAATTAAAA
ATGTTAGATGTATTTGCGTT

Product: pentose-5-phosphate-3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNNKKVAVSIYVFNFLEIGKKIDELIEAGMEWIHVDIMDGNFVNNYALCQKFCKDIKDKYPKIKVDAHMMCSNSEKYIES
FAEAGCDYFIFHYETLTDKNPITVNNIINKIKSYNMKPIIALNPETSFEHIKTYCDDLYAVMCMNILPGFNGQKIIESSY
SKINIINKYRKENNKVFKIMTDGGLREDTYKEILDAGADIVVVGAFVNVENNKLKGQFEKIKNYEIK

Sequences:

>Translated_227_residues
MNNKKVAVSIYVFNFLEIGKKIDELIEAGME*IHVDIMDGNFVNNYALCQKFCKDIKDKYPKIKVDAHMMCSNSEKYIES
FAEAGCDYFIFHYETLTDKNPITVNNIINKIKSYNMKPIIALNPETSFEHIKTYCDDLYAVMCMNILPGFNGQKIIESSY
SKINIINKYRKENNKVFKIMTDGGLREDTYKEILDAGADIVVVGAFVNVENNKLKGQFEKIKNYEIK
>Mature_227_residues
MNNKKVAVSIYVFNFLEIGKKIDELIEAGME*IHVDIMDGNFVNNYALCQKFCKDIKDKYPKIKVDAHMMCSNSEKYIES
FAEAGCDYFIFHYETLTDKNPITVNNIINKIKSYNMKPIIALNPETSFEHIKTYCDDLYAVMCMNILPGFNGQKIIESSY
SKINIINKYRKENNKVFKIMTDGGLREDTYKEILDAGADIVVVGAFVNVENNKLKGQFEKIKNYEIK

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=204, Percent_Identity=27.4509803921569, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI219879828, Length=204, Percent_Identity=27.4509803921569, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI24307923, Length=153, Percent_Identity=26.1437908496732, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1790523, Length=199, Percent_Identity=30.6532663316583, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789788, Length=207, Percent_Identity=26.0869565217391, Blast_Score=94, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=201, Percent_Identity=30.8457711442786, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322341, Length=214, Percent_Identity=32.2429906542056, Blast_Score=113, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24586301, Length=205, Percent_Identity=28.2926829268293, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 26026; Mature: 26026

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKKVAVSIYVFNFLEIGKKIDELIEAGMEIHVDIMDGNFVNNYALCQKFCKDIKDKYP
CCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
KIKVDAHMMCSNSEKYIESFAEAGCDYFIFHYETLTDKNPITVNNIINKIKSYNMKPIIA
EEEECCEEEECCCHHHHHHHHHCCCCEEEEEEEEECCCCCEEHHHHHHHHHHCCCCEEEE
LNPETSFEHIKTYCDDLYAVMCMNILPGFNGQKIIESSYSKINIINKYRKENNKVFKIMT
ECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEEEEE
DGGLREDTYKEILDAGADIVVVGAFVNVENNKLKGQFEKIKNYEIK
CCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNKKVAVSIYVFNFLEIGKKIDELIEAGMEIHVDIMDGNFVNNYALCQKFCKDIKDKYP
CCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
KIKVDAHMMCSNSEKYIESFAEAGCDYFIFHYETLTDKNPITVNNIINKIKSYNMKPIIA
EEEECCEEEECCCHHHHHHHHHCCCCEEEEEEEEECCCCCEEHHHHHHHHHHCCCCEEEE
LNPETSFEHIKTYCDDLYAVMCMNILPGFNGQKIIESSYSKINIINKYRKENNKVFKIMT
ECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEEEEE
DGGLREDTYKEILDAGADIVVVGAFVNVENNKLKGQFEKIKNYEIK
CCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]