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The map label for this gene is bglC [H]

Identifier: 50365433

GI number: 50365433

Start: 722438

End: 723838

Strand: Reverse

Name: bglC [H]

Synonym: Mfl617

Alternate gene names: 50365433

Gene position: 723838-722438 (Counterclockwise)

Preceding gene: 50365434

Following gene: 50365432

Centisome position: 91.25

GC content: 29.62

Gene sequence:

>1401_bases
ATGAATAAATTTCCAAAAGATTTTTTATGGGGTGCAGCTACAAGCGCCTATCAAGTAGAAGGGGGTATATATCAAGGCGG
CAAAGTGCCATCATCAATGGACCCTTCATCAAAAAAACACGCAAACAAAGAAATAACAGATTTTAGTGTTGCAGCTGATC
ACTATAACCATTGAAAAGAAGATGTAGCTCTTATGGCAGAAATGGGATTTAAGTCATACAGATTTTCTATTTCATGACCA
AGAATAATTAAAGATAAGGAAGGTAATATAAATCAAGAAGGAATTGATTTTTATAATAACTTATTAGATGAACTAATTAA
AAATAATATTGAGCCAGTAGTTACAATTTTTCACTTTGATATTCCTATGTTTGTTGAAGATGATGGTGGATTAGAAAGCA
AAAATGTTTATAAACATTATGAAAGATATTGCTCAGTTTTGTTTAAAAATTTTGGTTCAAAAGTTAAATATTGATTAACA
GTTAATGAACTGAATGTTATGGTTTTAGTTTCACAAATCATAAATACAAATAAAGAAAAGTCTTCTTCAAATGAATGACA
AGTAATGCATAACATGAACGTTGTTCAAGCTAAGGCTATTCTAATGTGTAGGGAAATGTGTCCAGGAGTCAAAATAGGGC
CAGCACCCAACATATCAGTTAACTACCCAGCTTCATGTAAACCTGAAGATTTTACGGCTAAGTTAAACATGGATTTATTG
AGAAACTGAGTTTACTTAGATATTTTATGTAGAGGATCATATAGTAAAAAATTCTTAAAGTATTTGGAAGAAAATAATAA
ACAAATTAAAACAACTGAAGAAGAAATGGAATTATTTAAAGTAGCAAAACCTGATTTTATTGCGATTAATTATTATTCTT
CTGGAACTGTTGAAGCTATCAACAGTTCAAATGGAGATGATGGAGCAACAAACAATGACCAGCAATCTGGATTTGCATTT
AAAGGTTTTGCAAAATCAGTAAAAAACCCTAATCTTCAAAAAACTCAGTTTGGATGAGAAATTGATCCTGTTGGCTTTAG
AAATACTTTAAGAGAAGTTTGAGAAAGATATCAGTTACCAATTATGGTTACTGAAAATGGAATTGGTGCTAAAGATGTTT
TAACTGAAGATGGAAAAGTACATGACGATTATAGAATAGATTATTATAAAAAACATATTCATCAAATGGGACTAGCTATT
GAAGATGGCGTTGAGATGATAGGATATATGCCTTGAAGTGCTATTGATTTAGTTTCAACTCATGAAGGAATATCAAAAAG
ATATGGATTTATTTATGTCAATAGAGATGAATTTGATTTAAAAGATATGAAAAGAATAAGAAAAGACAGTTTCTATTGAT
ACAAAGAATTAATTAAAAACAACGGTGATTACAATGAATAA

Upstream 100 bases:

>100_bases
TAAAAAAACTTTCTAAATAGGAAAGTTTTTTTTAATGCCTTATTTATCAGGGCATATTAAAAATGCAAAGCATAAAATAA
AAATATAAGGAGGGAATTAT

Downstream 100 bases:

>100_bases
AAAAATTACTTACGATTTGGGTGGTTCATCAATTAAAAAAATAGTTTTTAATGATGATAAAGTAGAATTTAAAGATATTC
TTTACTTTACCCATTTAGAA

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MNKFPKDFLWGAATSAYQVEGGIYQGGKVPSSMDPSSKKHANKEITDFSVAADHYNHWKEDVALMAEMGFKSYRFSISWP
RIIKDKEGNINQEGIDFYNNLLDELIKNNIEPVVTIFHFDIPMFVEDDGGLESKNVYKHYERYCSVLFKNFGSKVKYWLT
VNELNVMVLVSQIINTNKEKSSSNEWQVMHNMNVVQAKAILMCREMCPGVKIGPAPNISVNYPASCKPEDFTAKLNMDLL
RNWVYLDILCRGSYSKKFLKYLEENNKQIKTTEEEMELFKVAKPDFIAINYYSSGTVEAINSSNGDDGATNNDQQSGFAF
KGFAKSVKNPNLQKTQFGWEIDPVGFRNTLREVWERYQLPIMVTENGIGAKDVLTEDGKVHDDYRIDYYKKHIHQMGLAI
EDGVEMIGYMPWSAIDLVSTHEGISKRYGFIYVNRDEFDLKDMKRIRKDSFYWYKELIKNNGDYNE

Sequences:

>Translated_466_residues
MNKFPKDFLWGAATSAYQVEGGIYQGGKVPSSMDPSSKKHANKEITDFSVAADHYNH*KEDVALMAEMGFKSYRFSIS*P
RIIKDKEGNINQEGIDFYNNLLDELIKNNIEPVVTIFHFDIPMFVEDDGGLESKNVYKHYERYCSVLFKNFGSKVKY*LT
VNELNVMVLVSQIINTNKEKSSSNE*QVMHNMNVVQAKAILMCREMCPGVKIGPAPNISVNYPASCKPEDFTAKLNMDLL
RN*VYLDILCRGSYSKKFLKYLEENNKQIKTTEEEMELFKVAKPDFIAINYYSSGTVEAINSSNGDDGATNNDQQSGFAF
KGFAKSVKNPNLQKTQFG*EIDPVGFRNTLREV*ERYQLPIMVTENGIGAKDVLTEDGKVHDDYRIDYYKKHIHQMGLAI
EDGVEMIGYMP*SAIDLVSTHEGISKRYGFIYVNRDEFDLKDMKRIRKDSFY*YKELIKNNGDYNE
>Mature_466_residues
MNKFPKDFLWGAATSAYQVEGGIYQGGKVPSSMDPSSKKHANKEITDFSVAADHYNH*KEDVALMAEMGFKSYRFSIS*P
RIIKDKEGNINQEGIDFYNNLLDELIKNNIEPVVTIFHFDIPMFVEDDGGLESKNVYKHYERYCSVLFKNFGSKVKY*LT
VNELNVMVLVSQIINTNKEKSSSNE*QVMHNMNVVQAKAILMCREMCPGVKIGPAPNISVNYPASCKPEDFTAKLNMDLL
RN*VYLDILCRGSYSKKFLKYLEENNKQIKTTEEEMELFKVAKPDFIAINYYSSGTVEAINSSNGDDGATNNDQQSGFAF
KGFAKSVKNPNLQKTQFG*EIDPVGFRNTLREV*ERYQLPIMVTENGIGAKDVLTEDGKVHDDYRIDYYKKHIHQMGLAI
EDGVEMIGYMP*SAIDLVSTHEGISKRYGFIYVNRDEFDLKDMKRIRKDSFY*YKELIKNNGDYNE

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=485, Percent_Identity=27.6288659793814, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI110681710, Length=481, Percent_Identity=27.027027027027, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI32481206, Length=493, Percent_Identity=28.8032454361055, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI28376633, Length=158, Percent_Identity=36.0759493670886, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI24497614, Length=488, Percent_Identity=25.6147540983607, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI2367174, Length=483, Percent_Identity=38.9233954451346, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=36.1344537815126, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1789070, Length=489, Percent_Identity=34.9693251533742, Blast_Score=266, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17552856, Length=487, Percent_Identity=31.6221765913758, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17539390, Length=483, Percent_Identity=30.4347826086957, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21356577, Length=494, Percent_Identity=27.1255060728745, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 51989; Mature: 51989

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFPKDFLWGAATSAYQVEGGIYQGGKVPSSMDPSSKKHANKEITDFSVAADHYNHKED
CCCCCCHHHHHCCCCCEEECCCEECCCCCCCCCCCCHHHHCCCCCCHHEEHHHCCCCHHH
VALMAEMGFKSYRFSISPRIIKDKEGNINQEGIDFYNNLLDELIKNNIEPVVTIFHFDIP
HHHHHHHCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCE
MFVEDDGGLESKNVYKHYERYCSVLFKNFGSKVKYLTVNELNVMVLVSQIINTNKEKSSS
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCC
NEQVMHNMNVVQAKAILMCREMCPGVKIGPAPNISVNYPASCKPEDFTAKLNMDLLRNVY
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEECCCCCCCCCCCEEEECHHHHHHHH
LDILCRGSYSKKFLKYLEENNKQIKTTEEEMELFKVAKPDFIAINYYSSGTVEAINSSNG
HHHHCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCC
DDGATNNDQQSGFAFKGFAKSVKNPNLQKTQFGEIDPVGFRNTLREVERYQLPIMVTENG
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCC
IGAKDVLTEDGKVHDDYRIDYYKKHIHQMGLAIEDGVEMIGYMPSAIDLVSTHEGISKRY
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GFIYVNRDEFDLKDMKRIRKDSFYYKELIKNNGDYNE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKFPKDFLWGAATSAYQVEGGIYQGGKVPSSMDPSSKKHANKEITDFSVAADHYNHKED
CCCCCCHHHHHCCCCCEEECCCEECCCCCCCCCCCCHHHHCCCCCCHHEEHHHCCCCHHH
VALMAEMGFKSYRFSISPRIIKDKEGNINQEGIDFYNNLLDELIKNNIEPVVTIFHFDIP
HHHHHHHCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCE
MFVEDDGGLESKNVYKHYERYCSVLFKNFGSKVKYLTVNELNVMVLVSQIINTNKEKSSS
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCC
NEQVMHNMNVVQAKAILMCREMCPGVKIGPAPNISVNYPASCKPEDFTAKLNMDLLRNVY
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEECCCCCCCCCCCEEEECHHHHHHHH
LDILCRGSYSKKFLKYLEENNKQIKTTEEEMELFKVAKPDFIAINYYSSGTVEAINSSNG
HHHHCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCC
DDGATNNDQQSGFAFKGFAKSVKNPNLQKTQFGEIDPVGFRNTLREVERYQLPIMVTENG
CCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCC
IGAKDVLTEDGKVHDDYRIDYYKKHIHQMGLAIEDGVEMIGYMPSAIDLVSTHEGISKRY
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
GFIYVNRDEFDLKDMKRIRKDSFYYKELIKNNGDYNE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]