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The map label for this gene is nanK [H]

Identifier: 50365432

GI number: 50365432

Start: 721513

End: 722445

Strand: Reverse

Name: nanK [H]

Synonym: Mfl616

Alternate gene names: 50365432

Gene position: 722445-721513 (Counterclockwise)

Preceding gene: 50365433

Following gene: 50365431

Centisome position: 91.08

GC content: 26.47

Gene sequence:

>933_bases
ATGAATAAAAAAATTACTTACGATTTGGGTGGTTCATCAATTAAAAAAATAGTTTTTAATGATGATAAAGTAGAATTTAA
AGATATTCTTTACTTTACCCATTTAGAAAAGAAAGGGTTTCAAGTTCCCCTAGAAAAAGTTTTAGATATAATATTGGATG
ATTTAAAAAACGAAAAAGACTATTTTGACTTAGGTATTTCAATTCCTGGTGTTTTAGACTCAGAAAAGAAAAAAGTAATA
ACTGAATCAGCATTTTGTGATGTTGAATTTGATATAAATGCAAAATTCTCAAAATTATATAATATGCAAAATTTTGAAAT
TGAAAATGACGGCAAATCAGCTGCGTTTGGCGAATTTAAATTTAGAAATGATCCAAAATTAATAAATTTTATTCATATTA
CAATTGGTTCTGCTTTAGGATGCGGAATCATAATTAATAGTAAACTTTATAAAGGAAGCAATTTTGAGGCTGGTCAAGCT
TCAGGAATGTTTAGCTCAATAAATGATAAAAATGATAAATCTGCTTACGCGTTGGACACAGGTCTGGGTACTTTAATTAT
GAAATACAAAAAAATCATTAACTCAAACGAAAATATTTCAGGTAAGTACATTTTTACTAAATTTAATGAAAAAGATCAAA
TTGTGTGTAAACTAGTTGATGAATGAACATCATCAATTGCTAAAGCAATAATTAACTTTCATCAATTATTGGATTTTGAT
TTGCTAACTATTGGTGGTGGTGTAAGCGAAAATAAACAGTTTATGAAAATGGTTATTGATAAGATTAAGTTTCATCGAAA
TTTTGATGCTAATAGCAAATTTTCAAAAAATCCAGTTTTTAATGTTGTCGAAAAATCAAAATTAAATAATGATGCAGGAT
GTTATGGAGTTTTTTATAAACTTTGCGAGCTTGAAGAAAAACAAAATGCATAA

Upstream 100 bases:

>100_bases
TATGTCAATAGAGATGAATTTGATTTAAAAGATATGAAAAGAATAAGAAAAGACAGTTTCTATTGATACAAAGAATTAAT
TAAAAACAACGGTGATTACA

Downstream 100 bases:

>100_bases
TAGCATTTTTGTTAACAACTTTCTATTTATAAAAGTTAAATTTATTTAATACGTAAAATATGCTAAATTTTAAATATTTG
AGAAAATCAAAATATAAAGG

Product: transcriptional regulator/sugar kinase

Products: NA

Alternate protein names: ManNAc kinase; N-acetyl-D-mannosamine kinase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNKKITYDLGGSSIKKIVFNDDKVEFKDILYFTHLEKKGFQVPLEKVLDIILDDLKNEKDYFDLGISIPGVLDSEKKKVI
TESAFCDVEFDINAKFSKLYNMQNFEIENDGKSAAFGEFKFRNDPKLINFIHITIGSALGCGIIINSKLYKGSNFEAGQA
SGMFSSINDKNDKSAYALDTGLGTLIMKYKKIINSNENISGKYIFTKFNEKDQIVCKLVDEWTSSIAKAIINFHQLLDFD
LLTIGGGVSENKQFMKMVIDKIKFHRNFDANSKFSKNPVFNVVEKSKLNNDAGCYGVFYKLCELEEKQNA

Sequences:

>Translated_310_residues
MNKKITYDLGGSSIKKIVFNDDKVEFKDILYFTHLEKKGFQVPLEKVLDIILDDLKNEKDYFDLGISIPGVLDSEKKKVI
TESAFCDVEFDINAKFSKLYNMQNFEIENDGKSAAFGEFKFRNDPKLINFIHITIGSALGCGIIINSKLYKGSNFEAGQA
SGMFSSINDKNDKSAYALDTGLGTLIMKYKKIINSNENISGKYIFTKFNEKDQIVCKLVDE*TSSIAKAIINFHQLLDFD
LLTIGGGVSENKQFMKMVIDKIKFHRNFDANSKFSKNPVFNVVEKSKLNNDAGCYGVFYKLCELEEKQNA
>Mature_310_residues
MNKKITYDLGGSSIKKIVFNDDKVEFKDILYFTHLEKKGFQVPLEKVLDIILDDLKNEKDYFDLGISIPGVLDSEKKKVI
TESAFCDVEFDINAKFSKLYNMQNFEIENDGKSAAFGEFKFRNDPKLINFIHITIGSALGCGIIINSKLYKGSNFEAGQA
SGMFSSINDKNDKSAYALDTGLGTLIMKYKKIINSNENISGKYIFTKFNEKDQIVCKLVDE*TSSIAKAIINFHQLLDFD
LLTIGGGVSENKQFMKMVIDKIKFHRNFDANSKFSKNPVFNVVEKSKLNNDAGCYGVFYKLCELEEKQNA

Specific function: Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family. NanK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.60 [H]

Molecular weight: Translated: 34927; Mature: 34927

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKITYDLGGSSIKKIVFNDDKVEFKDILYFTHLEKKGFQVPLEKVLDIILDDLKNEKD
CCCEEEEECCCCCEEEEEECCCCCCHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
YFDLGISIPGVLDSEKKKVITESAFCDVEFDINAKFSKLYNMQNFEIENDGKSAAFGEFK
EEEECCCCCCCCCCCHHHHEECCCEEEEEEECCCHHHHHCCCCCEEECCCCCCCEEEEEE
FRNDPKLINFIHITIGSALGCGIIINSKLYKGSNFEAGQASGMFSSINDKNDKSAYALDT
ECCCCCEEEEEEEEECCCCCCEEEEECEEECCCCCCCCCCCCCHHHCCCCCCCCEEEECC
GLGTLIMKYKKIINSNENISGKYIFTKFNEKDQIVCKLVDETSSIAKAIINFHQLLDFDL
CHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCE
LTIGGGVSENKQFMKMVIDKIKFHRNFDANSKFSKNPVFNVVEKSKLNNDAGCYGVFYKL
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHH
CELEEKQNA
HHHHHHCCC
>Mature Secondary Structure
MNKKITYDLGGSSIKKIVFNDDKVEFKDILYFTHLEKKGFQVPLEKVLDIILDDLKNEKD
CCCEEEEECCCCCEEEEEECCCCCCHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
YFDLGISIPGVLDSEKKKVITESAFCDVEFDINAKFSKLYNMQNFEIENDGKSAAFGEFK
EEEECCCCCCCCCCCHHHHEECCCEEEEEEECCCHHHHHCCCCCEEECCCCCCCEEEEEE
FRNDPKLINFIHITIGSALGCGIIINSKLYKGSNFEAGQASGMFSSINDKNDKSAYALDT
ECCCCCEEEEEEEEECCCCCCEEEEECEEECCCCCCCCCCCCCHHHCCCCCCCCEEEECC
GLGTLIMKYKKIINSNENISGKYIFTKFNEKDQIVCKLVDETSSIAKAIINFHQLLDFDL
CHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCE
LTIGGGVSENKQFMKMVIDKIKFHRNFDANSKFSKNPVFNVVEKSKLNNDAGCYGVFYKL
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHH
CELEEKQNA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA