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The map label for this gene is 50365364

Identifier: 50365364

GI number: 50365364

Start: 640594

End: 641214

Strand: Reverse

Name: 50365364

Synonym: Mfl547

Alternate gene names: NA

Gene position: 641214-640594 (Counterclockwise)

Preceding gene: 50365365

Following gene: 50365363

Centisome position: 80.84

GC content: 25.76

Gene sequence:

>621_bases
ATGAAAATAGCAATTTTTGGAACAGTAGGAGCAGGTAAATCATCAATATCACAAGAATTATCAGAAAGATTAAATTATGA
AATTTTTCCTGAGCCAATAGATGAAAACCCCTACTTTGAAGATTATTACAAAGATATTAAGGCTTATGCTTTTAGAATGC
AAATATTTATGTTAACAGCTAGATCAAAACAATTATTTGCAGCAAAAGATTTAAAAAATAAAATTTTTGACAGAACAATT
ATTGAAGATCCGATTTTCATGAATGTTGGTCATAAAATGGGAAATGTTAATGACACAGACTACAAAACATATTGTGATTT
TTTCCAATATGTTGTATCAGAAAACTTAAGATATCCTAATGATAGATTAAAGTTTGATTTAGTTGTTTACTTAAAGGTTT
CAGATGAAACTTCAATTAGAAGAATCAATGAAAGAGGAAGAGCTGCTGAATTAAGCATTGACAAAAACTATTGAAAAATA
TTGAATGAATCATACGAAGAATATTATCAAGAACATAAAAATGATTTTCCATTTTTAGTAATTGATGCAAACAATGATAA
CTTAAACGAAAAAGTTGAAGAAGTTATAAGAAATATAGAAAAAATTAAAAAGGAGTTTTAA

Upstream 100 bases:

>100_bases
TATAGAGAATTAAAACCTCATGAGGTTAAAAAATTCTATGGAATTTATCAATCAACAAAAAGAAAAGAAGACTTAAAAAT
TAAATAAAGAGGTATATATT

Downstream 100 bases:

>100_bases
TATGGGAAGAGCACACGAAGTCCGCGCCGCCTCAATGGCTAAAACAGCTGCAAAAAAATCTGCAGCTAATGGTAGAGCAA
GTAAAGAAATTTATATGGCA

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DADO kinase; DAK; Deoxynucleoside kinase complex I S-component [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKIAIFGTVGAGKSSISQELSERLNYEIFPEPIDENPYFEDYYKDIKAYAFRMQIFMLTARSKQLFAAKDLKNKIFDRTI
IEDPIFMNVGHKMGNVNDTDYKTYCDFFQYVVSENLRYPNDRLKFDLVVYLKVSDETSIRRINERGRAAELSIDKNYWKI
LNESYEEYYQEHKNDFPFLVIDANNDNLNEKVEEVIRNIEKIKKEF

Sequences:

>Translated_206_residues
MKIAIFGTVGAGKSSISQELSERLNYEIFPEPIDENPYFEDYYKDIKAYAFRMQIFMLTARSKQLFAAKDLKNKIFDRTI
IEDPIFMNVGHKMGNVNDTDYKTYCDFFQYVVSENLRYPNDRLKFDLVVYLKVSDETSIRRINERGRAAELSIDKNY*KI
LNESYEEYYQEHKNDFPFLVIDANNDNLNEKVEEVIRNIEKIKKEF
>Mature_206_residues
MKIAIFGTVGAGKSSISQELSERLNYEIFPEPIDENPYFEDYYKDIKAYAFRMQIFMLTARSKQLFAAKDLKNKIFDRTI
IEDPIFMNVGHKMGNVNDTDYKTYCDFFQYVVSENLRYPNDRLKFDLVVYLKVSDETSIRRINERGRAAELSIDKNY*KI
LNESYEEYYQEHKNDFPFLVIDANNDNLNEKVEEVIRNIEKIKKEF

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.76 [H]

Molecular weight: Translated: 24361; Mature: 24361

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIFGTVGAGKSSISQELSERLNYEIFPEPIDENPYFEDYYKDIKAYAFRMQIFMLTA
CEEEEEEECCCCHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEC
RSKQLFAAKDLKNKIFDRTIIEDPIFMNVGHKMGNVNDTDYKTYCDFFQYVVSENLRYPN
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
DRLKFDLVVYLKVSDETSIRRINERGRAAELSIDKNYKILNESYEEYYQEHKNDFPFLVI
CCEEEEEEEEEEECCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEE
DANNDNLNEKVEEVIRNIEKIKKEF
ECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIAIFGTVGAGKSSISQELSERLNYEIFPEPIDENPYFEDYYKDIKAYAFRMQIFMLTA
CEEEEEEECCCCHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEC
RSKQLFAAKDLKNKIFDRTIIEDPIFMNVGHKMGNVNDTDYKTYCDFFQYVVSENLRYPN
CCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
DRLKFDLVVYLKVSDETSIRRINERGRAAELSIDKNYKILNESYEEYYQEHKNDFPFLVI
CCEEEEEEEEEEECCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEE
DANNDNLNEKVEEVIRNIEKIKKEF
ECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA