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The map label for this gene is secY [H]

Identifier: 50364957

GI number: 50364957

Start: 156258

End: 157718

Strand: Direct

Name: secY [H]

Synonym: Mfl142

Alternate gene names: 50364957

Gene position: 156258-157718 (Clockwise)

Preceding gene: 50364956

Following gene: 50364958

Centisome position: 19.7

GC content: 30.94

Gene sequence:

>1461_bases
ATGGCAAAAAAGTTCGCTAAAAAAAGCAAACAATATTCAGCCAAAAAATCACAAAGTAATAATAGCGATTTAAGAACTGG
CAACTTCTTTATTAAAAATAAAGATATTCTAGGTAGAATCGCTTTTACTTTATTATTATTAGTGATTATTAGAATTGGAG
TATATATAACAGTACCTGGTATCAGATTGACTTCTGATTATCAAAATGCTATTAACAATTCACAGTTCTTTCAATTACTT
TCAACTTTGGGGGGAGGTACTATTGGAAGATTCTCGATTCTAGCATTAGGGGTATCTCCTTATATTACTGCTTCCATTAT
TGTTCAGTTGCTTTCAACTGATGTTGTTCCTATCTTAACTAGATGAAATAAATCTGGTGAAAGAGGAAGAAAGAAATTAG
ATAAATTAACAAAAGTATTAATGATTCCATTTGCTTTAATGCAAGGGATTGCAACGATATTTACACTTCAACAACAAGGT
GTTATTGAACCTGGTTGATCAAGTGATAATGTATTAGCTTCTCCAGCATTTTACTATGTATTAGTACCACTTGTTATGTT
AGCTGGTTCATACTTTATGTTATGAATTGCTGATCAAATTACAATCAAAGGTGTTGGTAATGGTATTTCAATAGTTATCT
TTATTGGTATTATTGTTCAATTGCCTAACCAAATAAAAGCTACATATGATTTCTGAATACCTTCAAATGAAAGTATTAAC
GTTTTCTTTGACGGAATAATTAAGTTTTCTATTTACATGTTAGTTTTCTTTGTTGTTATATTCTCTGTTGTACTTATGAA
TGAAGCAGAACGTAAAGTGCCTATTCAGCAGACCGGTAGTGGTTTAATTGATTCAAAAGATCATACACCATATCTACCAC
TAAAACTGAATAATGCCGGGGTTATACCAGTTATCTTTGCATCTGCATTGATATCAACTCCAATTACAATTGCACAAATT
ATTGACCCAACAGCTAGCACGTCTACCGTTGATTCGGCAAATGCATTTGTAAGGTTTACACAACATTACCTTTCATTTAA
TACGTGATGAGGAATTGGAATATTTGCTGTAATGATTGTATTATTTACATTCTTATATGCTCAAGTTCAAATTAATCCTG
AAAAAATAAGTGAGAACTTTCAAAAATCAGGAACTTTCATTCCTGGGATTAAACCTGGAAAAGATACAACAAATTTCTTA
AAAGGAACTATTAATAGATTGTCTTTATTTGGTGCTATATTCTTAGCTGCAATTGCTGCGTTGCCATATGTTATATCTAA
ATTGACTAATTTACCAAGTCAGTTAGCTATTGGGGGAACCGGTTTAATTATTTGTATATCGGTTGCTATTCAAACAACAC
AACAATTACAAGGAAGAATTACACAACACAAATTTATTGAAAGCAAAAAACAAAACTTTACTGAAGAAGCCTCAACAAAT
TCTTCAAGTCATATTTGATAA

Upstream 100 bases:

>100_bases
GGTTCAATTACTTCAGCAATTAATGTAAAATTAAACAAAGTTTCAAAATCAGCTCAAGCTGAAATTGAAAAACTTGGAGG
AAAAGTAGAGGTGATTTAAT

Downstream 100 bases:

>100_bases
AAGACTATCAGTAGTCTTTTTTCTTTTGGTTTAAACCTATTTTTAGATATAATATAATTGTTATGAAAGAGGTAAAGATG
ACTGAAAAGCAAAATGTATT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MAKKFAKKSKQYSAKKSQSNNSDLRTGNFFIKNKDILGRIAFTLLLLVIIRIGVYITVPGIRLTSDYQNAINNSQFFQLL
STLGGGTIGRFSILALGVSPYITASIIVQLLSTDVVPILTRWNKSGERGRKKLDKLTKVLMIPFALMQGIATIFTLQQQG
VIEPGWSSDNVLASPAFYYVLVPLVMLAGSYFMLWIADQITIKGVGNGISIVIFIGIIVQLPNQIKATYDFWIPSNESIN
VFFDGIIKFSIYMLVFFVVIFSVVLMNEAERKVPIQQTGSGLIDSKDHTPYLPLKLNNAGVIPVIFASALISTPITIAQI
IDPTASTSTVDSANAFVRFTQHYLSFNTWWGIGIFAVMIVLFTFLYAQVQINPEKISENFQKSGTFIPGIKPGKDTTNFL
KGTINRLSLFGAIFLAAIAALPYVISKLTNLPSQLAIGGTGLIICISVAIQTTQQLQGRITQHKFIESKKQNFTEEASTN
SSSHIW

Sequences:

>Translated_486_residues
MAKKFAKKSKQYSAKKSQSNNSDLRTGNFFIKNKDILGRIAFTLLLLVIIRIGVYITVPGIRLTSDYQNAINNSQFFQLL
STLGGGTIGRFSILALGVSPYITASIIVQLLSTDVVPILTR*NKSGERGRKKLDKLTKVLMIPFALMQGIATIFTLQQQG
VIEPG*SSDNVLASPAFYYVLVPLVMLAGSYFML*IADQITIKGVGNGISIVIFIGIIVQLPNQIKATYDF*IPSNESIN
VFFDGIIKFSIYMLVFFVVIFSVVLMNEAERKVPIQQTGSGLIDSKDHTPYLPLKLNNAGVIPVIFASALISTPITIAQI
IDPTASTSTVDSANAFVRFTQHYLSFNT**GIGIFAVMIVLFTFLYAQVQINPEKISENFQKSGTFIPGIKPGKDTTNFL
KGTINRLSLFGAIFLAAIAALPYVISKLTNLPSQLAIGGTGLIICISVAIQTTQQLQGRITQHKFIESKKQNFTEEASTN
SSSHI*
>Mature_485_residues
AKKFAKKSKQYSAKKSQSNNSDLRTGNFFIKNKDILGRIAFTLLLLVIIRIGVYITVPGIRLTSDYQNAINNSQFFQLLS
TLGGGTIGRFSILALGVSPYITASIIVQLLSTDVVPILTR*NKSGERGRKKLDKLTKVLMIPFALMQGIATIFTLQQQGV
IEPG*SSDNVLASPAFYYVLVPLVMLAGSYFML*IADQITIKGVGNGISIVIFIGIIVQLPNQIKATYDF*IPSNESINV
FFDGIIKFSIYMLVFFVVIFSVVLMNEAERKVPIQQTGSGLIDSKDHTPYLPLKLNNAGVIPVIFASALISTPITIAQII
DPTASTSTVDSANAFVRFTQHYLSFNT**GIGIFAVMIVLFTFLYAQVQINPEKISENFQKSGTFIPGIKPGKDTTNFLK
GTINRLSLFGAIFLAAIAALPYVISKLTNLPSQLAIGGTGLIICISVAIQTTQQLQGRITQHKFIESKKQNFTEEASTNS
SSHI*

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=445, Percent_Identity=31.0112359550562, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 52150; Mature: 52019

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKFAKKSKQYSAKKSQSNNSDLRTGNFFIKNKDILGRIAFTLLLLVIIRIGVYITVPG
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCEEEECC
IRLTSDYQNAINNSQFFQLLSTLGGGTIGRFSILALGVSPYITASIIVQLLSTDVVPILT
EEECCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEE
RNKSGERGRKKLDKLTKVLMIPFALMQGIATIFTLQQQGVIEPGSSDNVLASPAFYYVLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHH
PLVMLAGSYFMLIADQITIKGVGNGISIVIFIGIIVQLPNQIKATYDFIPSNESINVFFD
HHHHHHCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHEECCCCCCEEHHHH
GIIKFSIYMLVFFVVIFSVVLMNEAERKVPIQQTGSGLIDSKDHTPYLPLKLNNAGVIPV
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCCCCCCCCCCCCEEEEEECCCCCHHH
IFASALISTPITIAQIIDPTASTSTVDSANAFVRFTQHYLSFNTGIGIFAVMIVLFTFLY
HHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQVQINPEKISENFQKSGTFIPGIKPGKDTTNFLKGTINRLSLFGAIFLAAIAALPYVIS
HHHEECHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLTNLPSQLAIGGTGLIICISVAIQTTQQLQGRITQHKFIESKKQNFTEEASTNSSSHI
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
AKKFAKKSKQYSAKKSQSNNSDLRTGNFFIKNKDILGRIAFTLLLLVIIRIGVYITVPG
CCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCEEEECC
IRLTSDYQNAINNSQFFQLLSTLGGGTIGRFSILALGVSPYITASIIVQLLSTDVVPILT
EEECCHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEE
RNKSGERGRKKLDKLTKVLMIPFALMQGIATIFTLQQQGVIEPGSSDNVLASPAFYYVLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHH
PLVMLAGSYFMLIADQITIKGVGNGISIVIFIGIIVQLPNQIKATYDFIPSNESINVFFD
HHHHHHCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHEECCCCCCEEHHHH
GIIKFSIYMLVFFVVIFSVVLMNEAERKVPIQQTGSGLIDSKDHTPYLPLKLNNAGVIPV
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCCCCCCCCCCCCEEEEEECCCCCHHH
IFASALISTPITIAQIIDPTASTSTVDSANAFVRFTQHYLSFNTGIGIFAVMIVLFTFLY
HHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AQVQINPEKISENFQKSGTFIPGIKPGKDTTNFLKGTINRLSLFGAIFLAAIAALPYVIS
HHHEECHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLTNLPSQLAIGGTGLIICISVAIQTTQQLQGRITQHKFIESKKQNFTEEASTNSSSHI
HHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3481422 [H]