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The map label for this gene is yabD [H]

Identifier: 50364862

GI number: 50364862

Start: 62639

End: 63439

Strand: Direct

Name: yabD [H]

Synonym: Mfl047

Alternate gene names: 50364862

Gene position: 62639-63439 (Clockwise)

Preceding gene: 50364860

Following gene: 50364863

Centisome position: 7.9

GC content: 26.22

Gene sequence:

>801_bases
ATGTTAAAAGAAAATAAGATTTTTGATGCACACATACATTTTAATGATGATTATAAATATACAAATGAAATGATAGAACC
TATGATTAATGAAGCTATTAAAAATGATGTTGAAGGTTTTTTATGCGCAAGCTTTGATATTAATTCAAGTAAAAAAGCTG
TTGAACTTTCTAAAAAATATAAAGGAATTGTTTTTGCAGGTATTGCTATTCATCCAAACGATGTTTCAAAAAATAATTTT
TCAGTTATGGAAGAATTAGATGAATTAGCAAAAGAAGCAGAGGTTATAGCAATTGGTGAAACAGGTCTTGATTATTTTTA
TACTAAGGAAGACGCAGAGTTGCAAAAAACATTTTTTAAAAAACATATTGAGTTAGCAAAAAAACATAATAAAGCATTGC
AAATACATATAAGAGATCACGTTAATGTTTTTGAAGCATATGATGATGTTGTTGAAATTTTAAAAGAATATAATTTAGAA
AAAGTTATAGTACATTGCTTTTCGGCTAATTCTATATACGCACAAAAATTTTTGGATTTAGGTTGTTACATAAATATAGG
GGGTGCAGTAACTTTTAAAAATGCAAAAGTGCTTCAAGAAGCCGTTGAAATTATACCTTTAGAAAAAATGCTAGTTGAAA
CAGACGCACCTTATTTAACACCACATCCACATAGAGGACAATTAAACGAAGCAAAATTTATTAATTTAACTGTTGAGAAA
ATTGCAGAAATAAAAAATGTAACTAAAGAAGAAGTAATAAAATTAACAACAAGCAACGCTAAATTAATTTTTAATATTTA
A

Upstream 100 bases:

>100_bases
AATAATTTACTCATAAAAATATTCTCCTTTTTATTATTTTAATTATATCACTAAAAGTTTATAATCAATATTAACAAAAC
AACTGAAAAGGAATATAAAA

Downstream 100 bases:

>100_bases
AAGTTTTATAATTAAAGAGTAAGAGAAAAAGAGGATTACATAATGGCAGGAGTATATGATACACATTGTCACTTAAATGA
CAATATTTATATTGAAAATG

Product: Mg2+ dependent DNAse

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLKENKIFDAHIHFNDDYKYTNEMIEPMINEAIKNDVEGFLCASFDINSSKKAVELSKKYKGIVFAGIAIHPNDVSKNNF
SVMEELDELAKEAEVIAIGETGLDYFYTKEDAELQKTFFKKHIELAKKHNKALQIHIRDHVNVFEAYDDVVEILKEYNLE
KVIVHCFSANSIYAQKFLDLGCYINIGGAVTFKNAKVLQEAVEIIPLEKMLVETDAPYLTPHPHRGQLNEAKFINLTVEK
IAEIKNVTKEEVIKLTTSNAKLIFNI

Sequences:

>Translated_266_residues
MLKENKIFDAHIHFNDDYKYTNEMIEPMINEAIKNDVEGFLCASFDINSSKKAVELSKKYKGIVFAGIAIHPNDVSKNNF
SVMEELDELAKEAEVIAIGETGLDYFYTKEDAELQKTFFKKHIELAKKHNKALQIHIRDHVNVFEAYDDVVEILKEYNLE
KVIVHCFSANSIYAQKFLDLGCYINIGGAVTFKNAKVLQEAVEIIPLEKMLVETDAPYLTPHPHRGQLNEAKFINLTVEK
IAEIKNVTKEEVIKLTTSNAKLIFNI
>Mature_266_residues
MLKENKIFDAHIHFNDDYKYTNEMIEPMINEAIKNDVEGFLCASFDINSSKKAVELSKKYKGIVFAGIAIHPNDVSKNNF
SVMEELDELAKEAEVIAIGETGLDYFYTKEDAELQKTFFKKHIELAKKHNKALQIHIRDHVNVFEAYDDVVEILKEYNLE
KVIVHCFSANSIYAQKFLDLGCYINIGGAVTFKNAKVLQEAVEIIPLEKMLVETDAPYLTPHPHRGQLNEAKFINLTVEK
IAEIKNVTKEEVIKLTTSNAKLIFNI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=227, Percent_Identity=29.9559471365639, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI110349734, Length=227, Percent_Identity=29.5154185022026, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI226061853, Length=233, Percent_Identity=29.1845493562232, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI226061614, Length=217, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI225903424, Length=199, Percent_Identity=29.1457286432161, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI14042943, Length=205, Percent_Identity=28.2926829268293, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226061595, Length=190, Percent_Identity=27.3684210526316, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI225903439, Length=184, Percent_Identity=29.3478260869565, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787342, Length=266, Percent_Identity=35.7142857142857, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI48994985, Length=243, Percent_Identity=29.6296296296296, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI87082439, Length=264, Percent_Identity=24.6212121212121, Blast_Score=107, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=245, Percent_Identity=29.3877551020408, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71980746, Length=226, Percent_Identity=31.858407079646, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=198, Percent_Identity=32.8282828282828, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17565396, Length=198, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=29.5774647887324, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30372; Mature: 30372

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKENKIFDAHIHFNDDYKYTNEMIEPMINEAIKNDVEGFLCASFDINSSKKAVELSKKY
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHC
KGIVFAGIAIHPNDVSKNNFSVMEELDELAKEAEVIAIGETGLDYFYTKEDAELQKTFFK
CCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCHHHHHHHHH
KHIELAKKHNKALQIHIRDHVNVFEAYDDVVEILKEYNLEKVIVHCFSANSIYAQKFLDL
HHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHEEHHHHHCCCCHHHHHHHCC
GCYINIGGAVTFKNAKVLQEAVEIIPLEKMLVETDAPYLTPHPHRGQLNEAKFINLTVEK
CCEEEECCEEEECHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHH
IAEIKNVTKEEVIKLTTSNAKLIFNI
HHHHHCCCHHHHEEEECCCCEEEEEC
>Mature Secondary Structure
MLKENKIFDAHIHFNDDYKYTNEMIEPMINEAIKNDVEGFLCASFDINSSKKAVELSKKY
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHC
KGIVFAGIAIHPNDVSKNNFSVMEELDELAKEAEVIAIGETGLDYFYTKEDAELQKTFFK
CCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCHHHHHHHHH
KHIELAKKHNKALQIHIRDHVNVFEAYDDVVEILKEYNLEKVIVHCFSANSIYAQKFLDL
HHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHEEHHHHHCCCCHHHHHHHCC
GCYINIGGAVTFKNAKVLQEAVEIIPLEKMLVETDAPYLTPHPHRGQLNEAKFINLTVEK
CCEEEECCEEEECHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHH
IAEIKNVTKEEVIKLTTSNAKLIFNI
HHHHHCCCHHHHEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]