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The map label for this gene is yabD [H]

Identifier: 50364863

GI number: 50364863

Start: 63482

End: 64273

Strand: Direct

Name: yabD [H]

Synonym: Mfl048

Alternate gene names: 50364863

Gene position: 63482-64273 (Clockwise)

Preceding gene: 50364862

Following gene: 50364864

Centisome position: 8.0

GC content: 29.29

Gene sequence:

>792_bases
ATGGCAGGAGTATATGATACACATTGTCACTTAAATGACAATATTTATATTGAAAATGAAATCTCAAGCAGCGAAATGGC
GGCTGAGGCTAAAAAAAGCGGAGTAGACATAATTAATAATGTTGGGTATGATATAAAATCATCAAAAGTTGCTTTAGTTC
AAGCACAAAAAAATAAACATGTTTGAGCATTAGTTGGAATACATCCAACACACGCACAATTTTTTACAGATGAAGCATAT
AATACTTTAGAGATTTTAGCTAACGCAGATAAAGTGGTTGGAATTGGTGAGACCGGTTTAGATTATTCAAGAGGCATTGA
ATATAAAAACCAACAAATTAGTGGATTTACAAAACAAGTTAAACTTGCTAAGAAAATGGATTTACCATTAATGTTACACG
TAAGGGATATTGAAGGATCAATTGATGCTTATCACGATGTTTTAGCTATATTAAAAAAAGAGAAATATCATAAAGCAGTT
TTACATGCTTTTAATGAAAGTTTAGAGATTGCAGAAATGTTTATTGAAAAAGGTATTCTAATATCAATAAATGGTCAAGT
TACAAGAGATAAAAATTTAAAAAAAGTTGTTAAAGAATTACCAATGAATAGTATAGTTGTTGAATCAGATGCACCTTACG
ATACACCTAAACCATACAATAAAAAAACTAATGCTCCAAAATATTTACCTTTAGTTGTTGAAGCAATAGCTAATATTAAA
AAAATGAGCAGATCTGATGTAGCAGAAATAACAAGGGATAATGCAGTTAGATTATTTTTCCCAAAAAGATAA

Upstream 100 bases:

>100_bases
TAAAGAAGAAGTAATAAAATTAACAACAAGCAACGCTAAATTAATTTTTAATATTTAAAAGTTTTATAATTAAAGAGTAA
GAGAAAAAGAGGATTACATA

Downstream 100 bases:

>100_bases
AAAACTTAGCAAACGCTAAGTTTTTTATTAGTCACAAGCACACTCACTCATTGTGCAATTGCAATCTTTACAAGTACAGC
TTTCTTTAGTGCAATCAGCA

Product: Mg2+ dependent DNAse

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MAGVYDTHCHLNDNIYIENEISSSEMAAEAKKSGVDIINNVGYDIKSSKVALVQAQKNKHVWALVGIHPTHAQFFTDEAY
NTLEILANADKVVGIGETGLDYSRGIEYKNQQISGFTKQVKLAKKMDLPLMLHVRDIEGSIDAYHDVLAILKKEKYHKAV
LHAFNESLEIAEMFIEKGILISINGQVTRDKNLKKVVKELPMNSIVVESDAPYDTPKPYNKKTNAPKYLPLVVEAIANIK
KMSRSDVAEITRDNAVRLFFPKR

Sequences:

>Translated_263_residues
MAGVYDTHCHLNDNIYIENEISSSEMAAEAKKSGVDIINNVGYDIKSSKVALVQAQKNKHV*ALVGIHPTHAQFFTDEAY
NTLEILANADKVVGIGETGLDYSRGIEYKNQQISGFTKQVKLAKKMDLPLMLHVRDIEGSIDAYHDVLAILKKEKYHKAV
LHAFNESLEIAEMFIEKGILISINGQVTRDKNLKKVVKELPMNSIVVESDAPYDTPKPYNKKTNAPKYLPLVVEAIANIK
KMSRSDVAEITRDNAVRLFFPKR
>Mature_262_residues
AGVYDTHCHLNDNIYIENEISSSEMAAEAKKSGVDIINNVGYDIKSSKVALVQAQKNKHV*ALVGIHPTHAQFFTDEAYN
TLEILANADKVVGIGETGLDYSRGIEYKNQQISGFTKQVKLAKKMDLPLMLHVRDIEGSIDAYHDVLAILKKEKYHKAVL
HAFNESLEIAEMFIEKGILISINGQVTRDKNLKKVVKELPMNSIVVESDAPYDTPKPYNKKTNAPKYLPLVVEAIANIKK
MSRSDVAEITRDNAVRLFFPKR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=28.6245353159851, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=28.6245353159851, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=28.2608695652174, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061614, Length=261, Percent_Identity=27.2030651340996, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI225903439, Length=253, Percent_Identity=28.0632411067194, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI14042943, Length=271, Percent_Identity=26.5682656826568, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI225903424, Length=279, Percent_Identity=26.8817204301075, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787342, Length=260, Percent_Identity=30.3846153846154, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI48994985, Length=248, Percent_Identity=29.8387096774194, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082439, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17559024, Length=261, Percent_Identity=27.9693486590038, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=209, Percent_Identity=32.0574162679426, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=242, Percent_Identity=30.1652892561983, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71980746, Length=276, Percent_Identity=25, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648690, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24586117, Length=254, Percent_Identity=29.5275590551181, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI221330018, Length=254, Percent_Identity=29.5275590551181, Blast_Score=91, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29323; Mature: 29192

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVYDTHCHLNDNIYIENEISSSEMAAEAKKSGVDIINNVGYDIKSSKVALVQAQKNKH
CCCCCCCEEEECCCEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEECCCCE
VALVGIHPTHAQFFTDEAYNTLEILANADKVVGIGETGLDYSRGIEYKNQQISGFTKQVK
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCCCCCHHHHHHHHHH
LAKKMDLPLMLHVRDIEGSIDAYHDVLAILKKEKYHKAVLHAFNESLEIAEMFIEKGILI
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEE
SINGQVTRDKNLKKVVKELPMNSIVVESDAPYDTPKPYNKKTNAPKYLPLVVEAIANIKK
EECCCEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MSRSDVAEITRDNAVRLFFPKR
HHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
AGVYDTHCHLNDNIYIENEISSSEMAAEAKKSGVDIINNVGYDIKSSKVALVQAQKNKH
CCCCCCEEEECCCEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEECCCCE
VALVGIHPTHAQFFTDEAYNTLEILANADKVVGIGETGLDYSRGIEYKNQQISGFTKQVK
EEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHCCCCCCCHHHHHHHHHH
LAKKMDLPLMLHVRDIEGSIDAYHDVLAILKKEKYHKAVLHAFNESLEIAEMFIEKGILI
HHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEE
SINGQVTRDKNLKKVVKELPMNSIVVESDAPYDTPKPYNKKTNAPKYLPLVVEAIANIKK
EECCCEECCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MSRSDVAEITRDNAVRLFFPKR
HHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]