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The map label for this gene is ygbD [C]

Identifier: 50364852

GI number: 50364852

Start: 51298

End: 52656

Strand: Direct

Name: ygbD [C]

Synonym: Mfl037

Alternate gene names: 50364852

Gene position: 51298-52656 (Clockwise)

Preceding gene: 50364851

Following gene: 50364853

Centisome position: 6.47

GC content: 30.83

Gene sequence:

>1359_bases
ATGAAAGTTATTGTTTTAGGTACTAACCATGCAGGAACAACTGCAGTTAGAACATTAAAAAGACTTAACCCAGAAATCGA
AGTTACTACTTATGATAGAAATGATGTTATTTCATTTTTAGGATGTGGAATCGCTTTATGAGTTAAAGGTGAAGTTAAAG
ATCCAAATGGATTATTTTACGCAACACCAGAAATTTTAGAATCAGAAGGAATCAATGTAAAAATGAAACATGAATGAGTT
TCAATTGATGCTGATAAAAAAACTGTTTTAATTAAAAACTTAGAAACAGGTGAAACATTCGAAGACAATTACGATAAAGT
TATTGTTGCAACAGGTACATGACCTTTATTACCACCAATCCCAGGATTAGACTTAAAAGGTGTACAAATTTGTAAAAACT
ATGACCATGCTAAAAAAATTCAACAAGCAAACCTAGATGATTCAATCAAAAAAGTTACTGTTGTAGGAGCTGGATATATT
GGAGTTGAATTAGTTGATGCATTTGTTGCTCATGGTAAAGAAGTTACATTAGTTGACTTTGCTGATAGAATCATGCCAGT
ATACTATGATGCAGAATTTACAAAACACGTTGAAGAAAGAATGGAAAAAGCTGGAGTTAAATTAGCTTTAAGCCAAGGTG
TTAAAGAATTTAAAGGTGCTAATGGAAAAGTTACACATGTTGTTACTGACAAAGAAGAAATTCCAACTGATTACGTAATC
TTCTCAGTTGGTGTAGTTGCTCAAACTAAACAATTAGAAGGTGTTGTTGAATTAAATGACAGAAAAGCTATTTTAACAAA
TGAATACTGTCAATCATCAAACCCAGATATTTATGCAATTGGAGATTGTTCAACAGTTTTCAATAAAGCATTAAACATGG
AAATGCCAATTCAATTAGCAACTACTGCAGTTAGAACAGGTATTCTTGCAGCAGCAAATATTGTTAATGGAAATAAATTA
GCATCACCAGGTTTCACAGGAGCAAATGGTATTGAAGTATTTGGATTTAAAATGGCTTCAGCTGGTGTAAGTGAAACAAG
TGCTAAAAAAATGGGATTAGATTATGAAGCAATTTTATTATCTGATTCAGACCGTCCAGAATTTATGTCAACTTATAAAG
AAGCTTGAATTAAATTAGTATGAGACAAAAAAACCAGAAAAATTATTGGAGCTCAAGTAGCTAGTGAAAATAACCATACA
GAAATTATGTATATGCTTTCATTAGGAATTCAAAAAGAATTAACTATTGATGAATTGCCATTAGTTGATATATTCTTCTT
ACCTCACTTCAACAAGCCATACAACTTTGTTACATTAGCAGGTTTAGAAGTATTAGGATTAAATTACTTTAAAAAATAA

Upstream 100 bases:

>100_bases
TTTATGTTATTTTTGAAAAATTTTCCAAAATTGTATAAATTTACACACTTTATTGGATATTTATTCCAATAAATAAAAAT
TATTAAGAGGAGTTATAAAT

Downstream 100 bases:

>100_bases
GATGATTAATCTATTTATTTCAAAATCAAACGATCCAGCATACAACTTAGCTGTTGAAGAGTATTTGACATATCATTACC
AAACTAAAGACCCTATTTTG

Product: NADH oxidase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKVIVLGTNHAGTTAVRTLKRLNPEIEVTTYDRNDVISFLGCGIALWVKGEVKDPNGLFYATPEILESEGINVKMKHEWV
SIDADKKTVLIKNLETGETFEDNYDKVIVATGTWPLLPPIPGLDLKGVQICKNYDHAKKIQQANLDDSIKKVTVVGAGYI
GVELVDAFVAHGKEVTLVDFADRIMPVYYDAEFTKHVEERMEKAGVKLALSQGVKEFKGANGKVTHVVTDKEEIPTDYVI
FSVGVVAQTKQLEGVVELNDRKAILTNEYCQSSNPDIYAIGDCSTVFNKALNMEMPIQLATTAVRTGILAAANIVNGNKL
ASPGFTGANGIEVFGFKMASAGVSETSAKKMGLDYEAILLSDSDRPEFMSTYKEAWIKLVWDKKTRKIIGAQVASENNHT
EIMYMLSLGIQKELTIDELPLVDIFFLPHFNKPYNFVTLAGLEVLGLNYFKK

Sequences:

>Translated_452_residues
MKVIVLGTNHAGTTAVRTLKRLNPEIEVTTYDRNDVISFLGCGIAL*VKGEVKDPNGLFYATPEILESEGINVKMKHE*V
SIDADKKTVLIKNLETGETFEDNYDKVIVATGT*PLLPPIPGLDLKGVQICKNYDHAKKIQQANLDDSIKKVTVVGAGYI
GVELVDAFVAHGKEVTLVDFADRIMPVYYDAEFTKHVEERMEKAGVKLALSQGVKEFKGANGKVTHVVTDKEEIPTDYVI
FSVGVVAQTKQLEGVVELNDRKAILTNEYCQSSNPDIYAIGDCSTVFNKALNMEMPIQLATTAVRTGILAAANIVNGNKL
ASPGFTGANGIEVFGFKMASAGVSETSAKKMGLDYEAILLSDSDRPEFMSTYKEA*IKLV*DKKTRKIIGAQVASENNHT
EIMYMLSLGIQKELTIDELPLVDIFFLPHFNKPYNFVTLAGLEVLGLNYFKK
>Mature_452_residues
MKVIVLGTNHAGTTAVRTLKRLNPEIEVTTYDRNDVISFLGCGIAL*VKGEVKDPNGLFYATPEILESEGINVKMKHE*V
SIDADKKTVLIKNLETGETFEDNYDKVIVATGT*PLLPPIPGLDLKGVQICKNYDHAKKIQQANLDDSIKKVTVVGAGYI
GVELVDAFVAHGKEVTLVDFADRIMPVYYDAEFTKHVEERMEKAGVKLALSQGVKEFKGANGKVTHVVTDKEEIPTDYVI
FSVGVVAQTKQLEGVVELNDRKAILTNEYCQSSNPDIYAIGDCSTVFNKALNMEMPIQLATTAVRTGILAAANIVNGNKL
ASPGFTGANGIEVFGFKMASAGVSETSAKKMGLDYEAILLSDSDRPEFMSTYKEA*IKLV*DKKTRKIIGAQVASENNHT
EIMYMLSLGIQKELTIDELPLVDIFFLPHFNKPYNFVTLAGLEVLGLNYFKK

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1789065, Length=307, Percent_Identity=25.4071661237785, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789765, Length=227, Percent_Identity=31.2775330396476, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788892, Length=217, Percent_Identity=26.7281105990783, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786307, Length=334, Percent_Identity=25.4491017964072, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17559934, Length=285, Percent_Identity=28.0701754385965, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565766, Length=317, Percent_Identity=25.8675078864353, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358499, Length=185, Percent_Identity=33.5135135135135, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639257, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359715, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359713, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639250, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18543267, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639252, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585130, Length=296, Percent_Identity=23.9864864864865, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48863; Mature: 48863

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIVLGTNHAGTTAVRTLKRLNPEIEVTTYDRNDVISFLGCGIALVKGEVKDPNGLFYA
CEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCEEEEECCCCCCCCEEEE
TPEILESEGINVKMKHEVSIDADKKTVLIKNLETGETFEDNYDKVIVATGTPLLPPIPGL
CHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCC
DLKGVQICKNYDHAKKIQQANLDDSIKKVTVVGAGYIGVELVDAFVAHGKEVTLVDFADR
CCCHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEEHHCC
IMPVYYDAEFTKHVEERMEKAGVKLALSQGVKEFKGANGKVTHVVTDKEEIPTDYVIFSV
CEEEEECHHHHHHHHHHHHHCCEEEEHHHCHHHHCCCCCEEEEEEECHHHCCCCEEEEEE
GVVAQTKQLEGVVELNDRKAILTNEYCQSSNPDIYAIGDCSTVFNKALNMEMPIQLATTA
CHHEEHHHHCCEEEECCCEEEEEHHHHCCCCCCEEEECCHHHHHHHHCCCCCCHHHHHHH
VRTGILAAANIVNGNKLASPGFTGANGIEVFGFKMASAGVSETSAKKMGLDYEAILLSDS
HHHHHHHHEEEECCCEECCCCCCCCCCEEEEEEEEECCCCCCCHHHHHCCCEEEEEEECC
DRPEFMSTYKEAIKLVDKKTRKIIGAQVASENNHTEIMYMLSLGIQKELTIDELPLVDIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEE
FLPHFNKPYNFVTLAGLEVLGLNYFKK
EECCCCCCCCEEEECCHHEECCHHHCC
>Mature Secondary Structure
MKVIVLGTNHAGTTAVRTLKRLNPEIEVTTYDRNDVISFLGCGIALVKGEVKDPNGLFYA
CEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHCCCEEEEECCCCCCCCEEEE
TPEILESEGINVKMKHEVSIDADKKTVLIKNLETGETFEDNYDKVIVATGTPLLPPIPGL
CHHHHHCCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCC
DLKGVQICKNYDHAKKIQQANLDDSIKKVTVVGAGYIGVELVDAFVAHGKEVTLVDFADR
CCCHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEEHHCC
IMPVYYDAEFTKHVEERMEKAGVKLALSQGVKEFKGANGKVTHVVTDKEEIPTDYVIFSV
CEEEEECHHHHHHHHHHHHHCCEEEEHHHCHHHHCCCCCEEEEEEECHHHCCCCEEEEEE
GVVAQTKQLEGVVELNDRKAILTNEYCQSSNPDIYAIGDCSTVFNKALNMEMPIQLATTA
CHHEEHHHHCCEEEECCCEEEEEHHHHCCCCCCEEEECCHHHHHHHHCCCCCCHHHHHHH
VRTGILAAANIVNGNKLASPGFTGANGIEVFGFKMASAGVSETSAKKMGLDYEAILLSDS
HHHHHHHHEEEECCCEECCCCCCCCCCEEEEEEEEECCCCCCCHHHHHCCCEEEEEEECC
DRPEFMSTYKEAIKLVDKKTRKIIGAQVASENNHTEIMYMLSLGIQKELTIDELPLVDIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEE
FLPHFNKPYNFVTLAGLEVLGLNYFKK
EECCCCCCCCEEEECCHHEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA