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The map label for this gene is oxaA [H]

Identifier: 50086619

GI number: 50086619

Start: 3595516

End: 3597267

Strand: Reverse

Name: oxaA [H]

Synonym: ACIAD3681

Alternate gene names: 50086619

Gene position: 3597267-3595516 (Counterclockwise)

Preceding gene: 50086620

Following gene: 50086618

Centisome position: 99.96

GC content: 43.84

Gene sequence:

>1752_bases
ATGCAACAATGGGCCAGGTTTGCAATTCTCGGGGCCATGTTTGTCACGGCATATTTGCTCATTTTGGCTTGGCAAAAAGA
TTATGGTCATGCAAATACAGCTGTTCAGCCACAAGCTGCTGCTGTTGTATCACATGACGTATCTGCTGATTTGCCAAACA
GCCAAAGTACTGCGGCAGCATCATCTGATGTGCCTCAGGCAAATATTGCTGCTCAACAAACACCTGCAGCAACATCAACC
GCTGCAAGTCAACAGCTTATTTCAATACAAACTGACCTTTATCATCTTTGGATCAATCCTAAAGGTGGTGATATTGTGCG
TATTGAATTACTCAATCACGATCAGAGCAAAAATAGCGATCAACCGTTTGTGATGCTTGAAAGTGATGCCAAACGTACCT
ATGTCGCGCAATCTGGTTTAATTGGTCTCAATGGTCCAGATAGTAGTCGAGGTGGTCGTCCTGTATTTGATGTTGAAAAA
TCGGCTTATACTTTAACAGACGCCAAAGAAACCAAGGATAAAGACGGAAAGCTAGTAAAAACTTTAACCGTTCCGATGGT
TTATAAAACGACTGATGGTGTTGAAATTATCAAGCGTTTTACCTTCAAACAAGGCGATTATCCAATTGTGGTGAGCTATC
AGGTGGTTAACCGTAGCCCGCAAAACTGGCAAGGTCAGATGTTTGGTCAGATTAAACGCGATAATTCTGAAGATCCAGGC
AAGTCAGATCAGGGTATCTTTACTTTGGGTACGTTCTTGGGCGGTGCTTGGGGCACACCTGAAGAGCATTACAACAAGCT
GAAGTTTGCCAATTTCTCTGATGAAAAGCTAAATGTTGAAGCAAAAGGTGGTTGGGTGGCAATGGTTCAGCACTACTTTG
TGAGTGCATGGATTCCAGGACACTTTGGAGATCAGGCCTATACGGCGAAGCTTGAATCACGTAAATCTGCCGATAACATG
AATATCATTGGCTTTACCTCTCCAACCATTAACGTACCAGCGGGCAAGACCATGACCGTTGATGCTACGTTCTATTCTGG
TCCAAAAATCCAGTCTGAATTAAAAGATCTGGCTGTGGGCTTGAATCAGACCGTCGATTATGGCTGGTTATGGCCAATTG
CCAAGTTACTGTTCATTGGCTTGCAATTTTTCCATAACATTGTTGGAAACTGGGGCTGGTCAATTATCTTGTTGACGGTA
TTGGTGAAGCTGATCTTGTGGCCGCTGTCTTCAAAGAGCTATCGCTCAATGGCCAAGATGCGTGTGATTGCACCTGAAAT
GCAACGCATGAAAGAAGAGTTTGGCGAAGACCGTATGCGTTTTTCTCAAGAGATGATGGCGTTGTACAAGCGTGAGCAAG
TCAATCCGCTATCGGGTTGCTTACCATTGCTACTTCAAATGCCGATCTTTCTGGCACTTTACTGGGTATTGATGGAAAGT
GTGGAATTACGCCATGCGCCTTGGATGTTGTGGATTCAGGATTTATCTGCAATGGATCCGTGGTTCATCCTTCCGCTGTT
GATGGGCGCAACCATGTTCATCCAGCAAATGCTGAACCCGCAACCAGCAGATCCAATGCAAGCGAAAGTTTTCCGCATTA
TGCCGATTATTTTTACGGTATTTATGCTGTTCTTCCCTGCAGGTCTGGTACTGTACTGGATTGTCAACAACACCATTACC
ATTACACAACAATGGTTTATTAATAAAAGTGTTGCAAAAGCTCGTGAAAATAAAGTGGAAACGACCTCATAA

Upstream 100 bases:

>100_bases
TTTCGTTTCAGCAAATAGATTCTCAAATGCTTCACGTTACTGTACCCTTTCGTGAACGTTTACTGAACCTAAATCACTCT
AACCACTTGGGGTAATAGAT

Downstream 100 bases:

>100_bases
TCGTTTGATACTTGAGAGCTGAATCAATCCGCTTAAGATGTTACGCTTAGGCGGATTTTTATTTGATCTGTATTTTTCTG
TTTTTAGGTTTCTATATGCA

Product: inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MQQWARFAILGAMFVTAYLLILAWQKDYGHANTAVQPQAAAVVSHDVSADLPNSQSTAAASSDVPQANIAAQQTPAATST
AASQQLISIQTDLYHLWINPKGGDIVRIELLNHDQSKNSDQPFVMLESDAKRTYVAQSGLIGLNGPDSSRGGRPVFDVEK
SAYTLTDAKETKDKDGKLVKTLTVPMVYKTTDGVEIIKRFTFKQGDYPIVVSYQVVNRSPQNWQGQMFGQIKRDNSEDPG
KSDQGIFTLGTFLGGAWGTPEEHYNKLKFANFSDEKLNVEAKGGWVAMVQHYFVSAWIPGHFGDQAYTAKLESRKSADNM
NIIGFTSPTINVPAGKTMTVDATFYSGPKIQSELKDLAVGLNQTVDYGWLWPIAKLLFIGLQFFHNIVGNWGWSIILLTV
LVKLILWPLSSKSYRSMAKMRVIAPEMQRMKEEFGEDRMRFSQEMMALYKREQVNPLSGCLPLLLQMPIFLALYWVLMES
VELRHAPWMLWIQDLSAMDPWFILPLLMGATMFIQQMLNPQPADPMQAKVFRIMPIIFTVFMLFFPAGLVLYWIVNNTIT
ITQQWFINKSVAKARENKVETTS

Sequences:

>Translated_583_residues
MQQWARFAILGAMFVTAYLLILAWQKDYGHANTAVQPQAAAVVSHDVSADLPNSQSTAAASSDVPQANIAAQQTPAATST
AASQQLISIQTDLYHLWINPKGGDIVRIELLNHDQSKNSDQPFVMLESDAKRTYVAQSGLIGLNGPDSSRGGRPVFDVEK
SAYTLTDAKETKDKDGKLVKTLTVPMVYKTTDGVEIIKRFTFKQGDYPIVVSYQVVNRSPQNWQGQMFGQIKRDNSEDPG
KSDQGIFTLGTFLGGAWGTPEEHYNKLKFANFSDEKLNVEAKGGWVAMVQHYFVSAWIPGHFGDQAYTAKLESRKSADNM
NIIGFTSPTINVPAGKTMTVDATFYSGPKIQSELKDLAVGLNQTVDYGWLWPIAKLLFIGLQFFHNIVGNWGWSIILLTV
LVKLILWPLSSKSYRSMAKMRVIAPEMQRMKEEFGEDRMRFSQEMMALYKREQVNPLSGCLPLLLQMPIFLALYWVLMES
VELRHAPWMLWIQDLSAMDPWFILPLLMGATMFIQQMLNPQPADPMQAKVFRIMPIIFTVFMLFFPAGLVLYWIVNNTIT
ITQQWFINKSVAKARENKVETTS
>Mature_583_residues
MQQWARFAILGAMFVTAYLLILAWQKDYGHANTAVQPQAAAVVSHDVSADLPNSQSTAAASSDVPQANIAAQQTPAATST
AASQQLISIQTDLYHLWINPKGGDIVRIELLNHDQSKNSDQPFVMLESDAKRTYVAQSGLIGLNGPDSSRGGRPVFDVEK
SAYTLTDAKETKDKDGKLVKTLTVPMVYKTTDGVEIIKRFTFKQGDYPIVVSYQVVNRSPQNWQGQMFGQIKRDNSEDPG
KSDQGIFTLGTFLGGAWGTPEEHYNKLKFANFSDEKLNVEAKGGWVAMVQHYFVSAWIPGHFGDQAYTAKLESRKSADNM
NIIGFTSPTINVPAGKTMTVDATFYSGPKIQSELKDLAVGLNQTVDYGWLWPIAKLLFIGLQFFHNIVGNWGWSIILLTV
LVKLILWPLSSKSYRSMAKMRVIAPEMQRMKEEFGEDRMRFSQEMMALYKREQVNPLSGCLPLLLQMPIFLALYWVLMES
VELRHAPWMLWIQDLSAMDPWFILPLLMGATMFIQQMLNPQPADPMQAKVFRIMPIIFTVFMLFFPAGLVLYWIVNNTIT
ITQQWFINKSVAKARENKVETTS

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI223718097, Length=204, Percent_Identity=28.921568627451, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790140, Length=521, Percent_Identity=46.6410748560461, Blast_Score=449, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24662345, Length=203, Percent_Identity=30.0492610837438, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356443, Length=203, Percent_Identity=30.0492610837438, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 65542; Mature: 65542

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQWARFAILGAMFVTAYLLILAWQKDYGHANTAVQPQAAAVVSHDVSADLPNSQSTAAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
SSDVPQANIAAQQTPAATSTAASQQLISIQTDLYHLWINPKGGDIVRIELLNHDQSKNSD
CCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCC
QPFVMLESDAKRTYVAQSGLIGLNGPDSSRGGRPVFDVEKSAYTLTDAKETKDKDGKLVK
CCEEEEECCCCEEEEECCCEEECCCCCCCCCCCCEEECCCCEEEECCCHHCCCCCCCEEE
TLTVPMVYKTTDGVEIIKRFTFKQGDYPIVVSYQVVNRSPQNWQGQMFGQIKRDNSEDPG
EEEEEEEEECCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHEEECCCCCCCC
KSDQGIFTLGTFLGGAWGTPEEHYNKLKFANFSDEKLNVEAKGGWVAMVQHYFVSAWIPG
CCCCCEEEEHHHHCCCCCCCHHHHCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCC
HFGDQAYTAKLESRKSADNMNIIGFTSPTINVPAGKTMTVDATFYSGPKIQSELKDLAVG
CCCCCHHHHHHHHCCCCCCCEEEEECCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHC
LNQTVDYGWLWPIAKLLFIGLQFFHNIVGNWGWSIILLTVLVKLILWPLSSKSYRSMAKM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RVIAPEMQRMKEEFGEDRMRFSQEMMALYKREQVNPLSGCLPLLLQMPIFLALYWVLMES
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VELRHAPWMLWIQDLSAMDPWFILPLLMGATMFIQQMLNPQPADPMQAKVFRIMPIIFTV
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
FMLFFPAGLVLYWIVNNTITITQQWFINKSVAKARENKVETTS
HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQQWARFAILGAMFVTAYLLILAWQKDYGHANTAVQPQAAAVVSHDVSADLPNSQSTAAA
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
SSDVPQANIAAQQTPAATSTAASQQLISIQTDLYHLWINPKGGDIVRIELLNHDQSKNSD
CCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCC
QPFVMLESDAKRTYVAQSGLIGLNGPDSSRGGRPVFDVEKSAYTLTDAKETKDKDGKLVK
CCEEEEECCCCEEEEECCCEEECCCCCCCCCCCCEEECCCCEEEECCCHHCCCCCCCEEE
TLTVPMVYKTTDGVEIIKRFTFKQGDYPIVVSYQVVNRSPQNWQGQMFGQIKRDNSEDPG
EEEEEEEEECCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHEEECCCCCCCC
KSDQGIFTLGTFLGGAWGTPEEHYNKLKFANFSDEKLNVEAKGGWVAMVQHYFVSAWIPG
CCCCCEEEEHHHHCCCCCCCHHHHCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCC
HFGDQAYTAKLESRKSADNMNIIGFTSPTINVPAGKTMTVDATFYSGPKIQSELKDLAVG
CCCCCHHHHHHHHCCCCCCCEEEEECCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHC
LNQTVDYGWLWPIAKLLFIGLQFFHNIVGNWGWSIILLTVLVKLILWPLSSKSYRSMAKM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RVIAPEMQRMKEEFGEDRMRFSQEMMALYKREQVNPLSGCLPLLLQMPIFLALYWVLMES
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VELRHAPWMLWIQDLSAMDPWFILPLLMGATMFIQQMLNPQPADPMQAKVFRIMPIIFTV
HHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
FMLFFPAGLVLYWIVNNTITITQQWFINKSVAKARENKVETTS
HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA