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The map label for this gene is actP [H]

Identifier: 50086426

GI number: 50086426

Start: 3387996

End: 3389732

Strand: Reverse

Name: actP [H]

Synonym: ACIAD3463

Alternate gene names: 50086426

Gene position: 3389732-3387996 (Counterclockwise)

Preceding gene: 50086427

Following gene: 50086424

Centisome position: 94.2

GC content: 43.7

Gene sequence:

>1737_bases
ATGAAAAAGGACTGCACTAAGATGAAATGGAATTCATTCAAAGCGTTGGCTTTAATGGCAGTTGGAGTACTCTTCTCTAC
ACTTGCGATGGCAAGTCCTGATCTGGGTCAGTCAGAGCAGCAAGCAACAAACTGGCATGCAATTATCATGTTTGTTGCGT
TTGTTGGAGGAACTTTGTTCATTACAAAATGGGCAGCCAAGCAAACCACCAGTACCAAAGATTTCTATACAGCAGGCGGC
GGTATTTCTGGTTTCCAGAATGGTCTGGCGATTGCTGGGGACTATATGTCGGCTGCTTCGTTCCTGGGTATTTCGGCTTT
AGTGTTTAGTTCAGGATTCGATGGTTTACTGTATTCTCTAGGTTTTATGGTGGGCTGGCCAATCGTATTGTTCTTGATTG
CCGAGCGCTTACGTAACTTGGGCAAATATAATCTATCTGATGTAGTGTCATTCCGTCTGGAAGAAAAGCCAGTGCGTACG
CTTGCTGCATTTAGCTCGCTGGTGGTTGTAGCATTTTATCTGATTGCGCAAATGGTGGGTGCAGGGCAATTGATCAAGCT
TCTCTTTGGCTTGAACTATAATATTGCGGTTGTGATTGTGGGTTTACTCATGATGGCTTATGTCATCTTTGGTGGCATGC
TAGCAACCACTTGGGTACAAATTATTAAAGCAGTGCTTTTGCTCTCAGGTGCAACCTTCATGGCATTTATGGTCATGAAA
GCAGTCGGCTTTAGCTTTAGTAACATGTTCACTCAGGCCATTGATGTTTATGCCAATGTTCGTAATATCAGTCTGGATGA
TGCAGCCAAGATTATGGGGCCAGGTAAACTCGCTGCGAATCCAATCGATGCGATTTCTCTTGGTTTGGCATTGATGTTTG
GTACTGCGGGATTGCCACATATTTTGATGCGTTTCTTTACAGTGAAAGATGCGAAAGAAGCACGTAAATCTGTTGTAGTG
GCTACAGGATTCATTGGTTATTTCTACCTGCTCACGTTTATTATTGGCTTCGGTGCGATTCTGTTTGTTTCAAACAATCC
ACAGTTCCTTGATGTTGCCAAAATGGCAGTGACAGGCAAACTTGAGTTGATGGGCGGGAATAACATGGCTGCGGTGCATT
TAAGTGATGCATTGGGCGGCGATTTATTCATGGGCTTCATTTCAGCAGTGGCTTTCGCAACCATTCTTGCGGTTGTTGCG
GGTTTAACGCTGTCTGGCGCCTCTGCGATTTCACACGACTTATATGCCAACGTATTTAGAAAAGGCAAAACTACGCCTGA
ATCTGAATTACGTATGTCTAAAATCGCAACACTTGGTCTTGCAATTTTTGCGATGATTTTGGGTATTCTGTTTGAAAAGC
AAAACGTGGCTTTCATGGTTGGTTTAGCATTCTCGGTTGCGTGTTGTGCCAATTTCCCAGTTCTTGTACTTTCAATGTTC
TGGAAAGGTTTAACTACGCGCGGTGCAGTGATTGGTGGTGTAGTTGGTTTAACAACTGCGGTGGTGCTCATTATTCTGTC
TAAAGCAGTGTGGGTGGATACTCTCAAGATTTCAGATACACCAATTAACCCATTTAATGGTCCTGCAATCTTTGCAATGC
CATTGTCATTCCTATGCTGCTGGTTCTTTTCAATCACAGATAACTCAGCACGTGCTAAAGCTGAACGTAAAGCATTTGAT
GCGCAATATGTTCGCTCAATGACAGGGGTTGGAATTTCAGGTGCATCGGATCACTAA

Upstream 100 bases:

>100_bases
GTTCTGTCATTTGTTCTATGTGGTGTCTATTCGTACATTGCAAACAATACACTCGATCAACTCAATGAAGAAGCATTGAG
AGAAGTCGAAAATATTACTC

Downstream 100 bases:

>100_bases
AAAATAAATTTAATAAAAAAAGCGCTTAGAGCGCTTTTTTTATTGCTTGGTATAGACCTGACCATTGAGTTGCATTTGCC
AGTGCTGGTTTTGTTGATAA

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MKKDCTKMKWNSFKALALMAVGVLFSTLAMASPDLGQSEQQATNWHAIIMFVAFVGGTLFITKWAAKQTTSTKDFYTAGG
GISGFQNGLAIAGDYMSAASFLGISALVFSSGFDGLLYSLGFMVGWPIVLFLIAERLRNLGKYNLSDVVSFRLEEKPVRT
LAAFSSLVVVAFYLIAQMVGAGQLIKLLFGLNYNIAVVIVGLLMMAYVIFGGMLATTWVQIIKAVLLLSGATFMAFMVMK
AVGFSFSNMFTQAIDVYANVRNISLDDAAKIMGPGKLAANPIDAISLGLALMFGTAGLPHILMRFFTVKDAKEARKSVVV
ATGFIGYFYLLTFIIGFGAILFVSNNPQFLDVAKMAVTGKLELMGGNNMAAVHLSDALGGDLFMGFISAVAFATILAVVA
GLTLSGASAISHDLYANVFRKGKTTPESELRMSKIATLGLAIFAMILGILFEKQNVAFMVGLAFSVACCANFPVLVLSMF
WKGLTTRGAVIGGVVGLTTAVVLIILSKAVWVDTLKISDTPINPFNGPAIFAMPLSFLCCWFFSITDNSARAKAERKAFD
AQYVRSMTGVGISGASDH

Sequences:

>Translated_578_residues
MKKDCTKMKWNSFKALALMAVGVLFSTLAMASPDLGQSEQQATNWHAIIMFVAFVGGTLFITKWAAKQTTSTKDFYTAGG
GISGFQNGLAIAGDYMSAASFLGISALVFSSGFDGLLYSLGFMVGWPIVLFLIAERLRNLGKYNLSDVVSFRLEEKPVRT
LAAFSSLVVVAFYLIAQMVGAGQLIKLLFGLNYNIAVVIVGLLMMAYVIFGGMLATTWVQIIKAVLLLSGATFMAFMVMK
AVGFSFSNMFTQAIDVYANVRNISLDDAAKIMGPGKLAANPIDAISLGLALMFGTAGLPHILMRFFTVKDAKEARKSVVV
ATGFIGYFYLLTFIIGFGAILFVSNNPQFLDVAKMAVTGKLELMGGNNMAAVHLSDALGGDLFMGFISAVAFATILAVVA
GLTLSGASAISHDLYANVFRKGKTTPESELRMSKIATLGLAIFAMILGILFEKQNVAFMVGLAFSVACCANFPVLVLSMF
WKGLTTRGAVIGGVVGLTTAVVLIILSKAVWVDTLKISDTPINPFNGPAIFAMPLSFLCCWFFSITDNSARAKAERKAFD
AQYVRSMTGVGISGASDH
>Mature_578_residues
MKKDCTKMKWNSFKALALMAVGVLFSTLAMASPDLGQSEQQATNWHAIIMFVAFVGGTLFITKWAAKQTTSTKDFYTAGG
GISGFQNGLAIAGDYMSAASFLGISALVFSSGFDGLLYSLGFMVGWPIVLFLIAERLRNLGKYNLSDVVSFRLEEKPVRT
LAAFSSLVVVAFYLIAQMVGAGQLIKLLFGLNYNIAVVIVGLLMMAYVIFGGMLATTWVQIIKAVLLLSGATFMAFMVMK
AVGFSFSNMFTQAIDVYANVRNISLDDAAKIMGPGKLAANPIDAISLGLALMFGTAGLPHILMRFFTVKDAKEARKSVVV
ATGFIGYFYLLTFIIGFGAILFVSNNPQFLDVAKMAVTGKLELMGGNNMAAVHLSDALGGDLFMGFISAVAFATILAVVA
GLTLSGASAISHDLYANVFRKGKTTPESELRMSKIATLGLAIFAMILGILFEKQNVAFMVGLAFSVACCANFPVLVLSMF
WKGLTTRGAVIGGVVGLTTAVVLIILSKAVWVDTLKISDTPINPFNGPAIFAMPLSFLCCWFFSITDNSARAKAERKAFD
AQYVRSMTGVGISGASDH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=483, Percent_Identity=22.5672877846791, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1790503, Length=543, Percent_Identity=66.1141804788214, Blast_Score=710, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=472, Percent_Identity=25.635593220339, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082237, Length=441, Percent_Identity=23.1292517006803, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 61735; Mature: 61735

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA