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The map label for this gene is pilQ [H]

Identifier: 50086334

GI number: 50086334

Start: 3262339

End: 3264510

Strand: Reverse

Name: pilQ [H]

Synonym: ACIAD3355

Alternate gene names: 50086334

Gene position: 3264510-3262339 (Counterclockwise)

Preceding gene: 50086335

Following gene: 50086333

Centisome position: 90.72

GC content: 41.67

Gene sequence:

>2172_bases
ATGAGAACAGATTTTAACGTTTTTACGACTGGGGGAGCTCCGATGAAACAGATCATACGTCAATTTTCGATCGGGACAGT
TGCTTATGCCATCATGCAGGTTGCAAGTGCTCAGGTTGCAATCACTAACGTGGTTCCAATGAATATTCCAGGACAAGGCA
CAGAAATTCGGGTCATGTTTAATGGATTGCCGCCTCAGCCTCAAGCCTATCAACTTGAGCAGCCAGCGCGTCTGATTCTG
GATTTTGATAAAGCAGGTCAGAAGCTTGCAAAAAGCTTGATTCCTGTGACCACTAATGAAGCTAGCTCAATTGATGTTAG
TTCGGATGATAAACGCGCCAGAGTTGTGGTTAATCTAAAAGATGCTGGCGCATTCACCACACGCGTTGAAGGCAATGTTT
TCATTCTTAAAATTAACAATATTCAATCGACTGCAACGCCTGTTGCAACGTCAGCACCTGCGCCTCAGCAGGGCATTGGT
AATATCGGTTTTCAGCGTGGTGCTCAAGGTGAAGGGCTGGTTGTTATTGATTTGCAAGGAACAAATACGCCTGTTGATGT
GCAGCAACAAGGCAGCAAAGTGGTGGTGCGTTTCCCAGGAATCAAAATACCCACACATTTAGCTCGTCGTCTAAATACAA
CTGATTTTGCAACACCTGTTGCTTCAATAGATTCCTATAATGATGGCAGTAATGGGGTTATTTCCATTCAGTCTACGGGT
AGCTACGAATATATGGCCTATCAGGCTGAAAATAAGCTCACCATTAGTTTAAAACGTCCGCAGGATAATGTACGCCTCAA
TTCCAAAAACAATCAGAATTATACAGGGAAAAAGATTTCTCTAGATTTTCAGGATATTGAAGTGCGCCGTGTACTACAGC
TACTTGCAGACTTCACCAATATTAATATGGTCACTGCCGATTCTGTACAGGGTAATATTACGTTGCATCTTAAAGATGTA
CCTTGGGATCAGGCACTGGATATTATTTTAAAAACAAAAAATCTGGATAAACGCCGTAATGGGAATGTGATCTGGATTGC
GCCTGTTTCAGAGTTGATTAAATCTGAAGAAGATGAAGCGAAGGCAATTGCGCAAAGTACCAAGCTTGCACCGCTACAAA
CTGAATATATTTTATTGAAATATGCTAAAGCTGCAGATATTGAAAAGTTAATTACCCAAGGGCGTAATAGTGGTACATCC
AATAGCAATACGAATGGCAGTGCGACTGTTGAACCTTTAGGCGATAGTGTTGGAACTTTGCTGAGTCCAAGAGGAACCAT
TTCCCTTGATCCGCGAACCAATACCTTAATTATTAATGATACCTCACAAAAAATTGACCAGATTCGTAAGATGATTGACT
TACTGGATATTCCAGTCAAGCAGGTGATGATTGAAGCACGGATCGTACGTGCGACGACATCTTTTAGTAAAGAAATGGGT
GTGAAATGGGGGATTTTATCTCAAGGTATCAATCAAAATAGCAATCTGTTAGTGGGCGGGAGTGAAACAACGCTTTGGAA
CTTGCGTAACCCTGATAGTAACGGGACGTATACGATAGAACGTCCAGACAATCTGAATGTGGATCTTGGTGTGACCACCA
CAGGTGCAAGCAGTATTGCCTTTGGTTTGATTAGTCTTTCTGATTTTATGCTGGATTTAGAACTTTCTGCGTTGCAGGCA
GATGGATATGGTGAAGTCATTTCGACACCTAAAGTCATGTCGGCAGATAAGCAAAAGGCTAAAGTTGCAACCGGTGTTGA
AGTTCCGTATCAATCAACAACCAATTCGGCTGCTGGTTCAACGGCGACAACATCATTTAAAGAAGCATTACTCAGCCTTG
AAGTAACACCTAATATTACCCCAGACGGCAAAATCTTGATGGAACTCAACATTGCCAACGACTCAATTAACAGTTATGCC
CAAAATGGCGAAGCGATTTTAAATAAAAATACCATTAACACCAATGTGCTGGTGAATAATGGCGAAACTGTAGTATTGGG
TGGCGTATTTGAGCAAACAACCAACAATGCCGTGACTAAAGTACCATTTTTAGGTGATCTTCCTTACGTTGGACGCCTAT
TTAAGAAGACGGCCAAAAGTGAGGCAAAAAATGAGCTGCTAATTTTTGTGACGCCTCGAATAGTTAATGACACTATTGTT
GGAAATCATTAA

Upstream 100 bases:

>100_bases
ATTTAATGGAAATTGTACCAGATGGACATGATGGGTATATCGAACGACCTCGAAGTTTGGTCTTAATTGGGCCTAAGCCT
TAAAGTATAAAGGGATAACA

Downstream 100 bases:

>100_bases
TATAGTTTTAATTCAAGTAATTCAATAGGTGACTCCTTGCCAAGCAAAGAGTTTGACACCCTGCCAAATATTTATTTGGT
AGGGCCCATGGGAGCAGGAA

Product: outer membrane protein (ComQ)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MRTDFNVFTTGGAPMKQIIRQFSIGTVAYAIMQVASAQVAITNVVPMNIPGQGTEIRVMFNGLPPQPQAYQLEQPARLIL
DFDKAGQKLAKSLIPVTTNEASSIDVSSDDKRARVVVNLKDAGAFTTRVEGNVFILKINNIQSTATPVATSAPAPQQGIG
NIGFQRGAQGEGLVVIDLQGTNTPVDVQQQGSKVVVRFPGIKIPTHLARRLNTTDFATPVASIDSYNDGSNGVISIQSTG
SYEYMAYQAENKLTISLKRPQDNVRLNSKNNQNYTGKKISLDFQDIEVRRVLQLLADFTNINMVTADSVQGNITLHLKDV
PWDQALDIILKTKNLDKRRNGNVIWIAPVSELIKSEEDEAKAIAQSTKLAPLQTEYILLKYAKAADIEKLITQGRNSGTS
NSNTNGSATVEPLGDSVGTLLSPRGTISLDPRTNTLIINDTSQKIDQIRKMIDLLDIPVKQVMIEARIVRATTSFSKEMG
VKWGILSQGINQNSNLLVGGSETTLWNLRNPDSNGTYTIERPDNLNVDLGVTTTGASSIAFGLISLSDFMLDLELSALQA
DGYGEVISTPKVMSADKQKAKVATGVEVPYQSTTNSAAGSTATTSFKEALLSLEVTPNITPDGKILMELNIANDSINSYA
QNGEAILNKNTINTNVLVNNGETVVLGGVFEQTTNNAVTKVPFLGDLPYVGRLFKKTAKSEAKNELLIFVTPRIVNDTIV
GNH

Sequences:

>Translated_723_residues
MRTDFNVFTTGGAPMKQIIRQFSIGTVAYAIMQVASAQVAITNVVPMNIPGQGTEIRVMFNGLPPQPQAYQLEQPARLIL
DFDKAGQKLAKSLIPVTTNEASSIDVSSDDKRARVVVNLKDAGAFTTRVEGNVFILKINNIQSTATPVATSAPAPQQGIG
NIGFQRGAQGEGLVVIDLQGTNTPVDVQQQGSKVVVRFPGIKIPTHLARRLNTTDFATPVASIDSYNDGSNGVISIQSTG
SYEYMAYQAENKLTISLKRPQDNVRLNSKNNQNYTGKKISLDFQDIEVRRVLQLLADFTNINMVTADSVQGNITLHLKDV
PWDQALDIILKTKNLDKRRNGNVIWIAPVSELIKSEEDEAKAIAQSTKLAPLQTEYILLKYAKAADIEKLITQGRNSGTS
NSNTNGSATVEPLGDSVGTLLSPRGTISLDPRTNTLIINDTSQKIDQIRKMIDLLDIPVKQVMIEARIVRATTSFSKEMG
VKWGILSQGINQNSNLLVGGSETTLWNLRNPDSNGTYTIERPDNLNVDLGVTTTGASSIAFGLISLSDFMLDLELSALQA
DGYGEVISTPKVMSADKQKAKVATGVEVPYQSTTNSAAGSTATTSFKEALLSLEVTPNITPDGKILMELNIANDSINSYA
QNGEAILNKNTINTNVLVNNGETVVLGGVFEQTTNNAVTKVPFLGDLPYVGRLFKKTAKSEAKNELLIFVTPRIVNDTIV
GNH
>Mature_723_residues
MRTDFNVFTTGGAPMKQIIRQFSIGTVAYAIMQVASAQVAITNVVPMNIPGQGTEIRVMFNGLPPQPQAYQLEQPARLIL
DFDKAGQKLAKSLIPVTTNEASSIDVSSDDKRARVVVNLKDAGAFTTRVEGNVFILKINNIQSTATPVATSAPAPQQGIG
NIGFQRGAQGEGLVVIDLQGTNTPVDVQQQGSKVVVRFPGIKIPTHLARRLNTTDFATPVASIDSYNDGSNGVISIQSTG
SYEYMAYQAENKLTISLKRPQDNVRLNSKNNQNYTGKKISLDFQDIEVRRVLQLLADFTNINMVTADSVQGNITLHLKDV
PWDQALDIILKTKNLDKRRNGNVIWIAPVSELIKSEEDEAKAIAQSTKLAPLQTEYILLKYAKAADIEKLITQGRNSGTS
NSNTNGSATVEPLGDSVGTLLSPRGTISLDPRTNTLIINDTSQKIDQIRKMIDLLDIPVKQVMIEARIVRATTSFSKEMG
VKWGILSQGINQNSNLLVGGSETTLWNLRNPDSNGTYTIERPDNLNVDLGVTTTGASSIAFGLISLSDFMLDLELSALQA
DGYGEVISTPKVMSADKQKAKVATGVEVPYQSTTNSAAGSTATTSFKEALLSLEVTPNITPDGKILMELNIANDSINSYA
QNGEAILNKNTINTNVLVNNGETVVLGGVFEQTTNNAVTKVPFLGDLPYVGRLFKKTAKSEAKNELLIFVTPRIVNDTIV
GNH

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=447, Percent_Identity=30.8724832214765, Blast_Score=223, Evalue=4e-59,
Organism=Escherichia coli, GI87082242, Length=358, Percent_Identity=28.2122905027933, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 78168; Mature: 78168

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDFNVFTTGGAPMKQIIRQFSIGTVAYAIMQVASAQVAITNVVPMNIPGQGTEIRVMF
CCCCCEEEECCCCHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCEEEEEE
NGLPPQPQAYQLEQPARLILDFDKAGQKLAKSLIPVTTNEASSIDVSSDDKRARVVVNLK
CCCCCCCCCEECCCCCEEEEEHHHHHHHHHHHHCCEECCCCCEECCCCCCCCEEEEEEEE
DAGAFTTRVEGNVFILKINNIQSTATPVATSAPAPQQGIGNIGFQRGAQGEGLVVIDLQG
CCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
TNTPVDVQQQGSKVVVRFPGIKIPTHLARRLNTTDFATPVASIDSYNDGSNGVISIQSTG
CCCCCCHHCCCCEEEEEECCCCCHHHHHHHCCCCHHCCCHHHCCCCCCCCCCEEEEEECC
SYEYMAYQAENKLTISLKRPQDNVRLNSKNNQNYTGKKISLDFQDIEVRRVLQLLADFTN
CEEEEEEECCCEEEEEEECCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCC
INMVTADSVQGNITLHLKDVPWDQALDIILKTKNLDKRRNGNVIWIAPVSELIKSEEDEA
CEEEEECCCCCEEEEEEECCCHHHHEEEEEEECCCCCCCCCCEEEEECHHHHHCCCCHHH
KAIAQSTKLAPLQTEYILLKYAKAADIEKLITQGRNSGTSNSNTNGSATVEPLGDSVGTL
HHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHH
LSPRGTISLDPRTNTLIINDTSQKIDQIRKMIDLLDIPVKQVMIEARIVRATTSFSKEMG
CCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHHHHC
VKWGILSQGINQNSNLLVGGSETTLWNLRNPDSNGTYTIERPDNLNVDLGVTTTGASSIA
CEEEHHHCCCCCCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEECCCHHHH
FGLISLSDFMLDLELSALQADGYGEVISTPKVMSADKQKAKVATGVEVPYQSTTNSAAGS
HHHHHHHHHHEEEEEEEEECCCCCCCCCCCCHHCCCCHHHHEECCCCCCCCCCCCCCCCC
TATTSFKEALLSLEVTPNITPDGKILMELNIANDSINSYAQNGEAILNKNTINTNVLVNN
CCHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCCCEEEECCCCEEEEEEEC
GETVVLGGVFEQTTNNAVTKVPFLGDLPYVGRLFKKTAKSEAKNELLIFVTPRIVNDTIV
CCEEEEECCHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCC
GNH
CCC
>Mature Secondary Structure
MRTDFNVFTTGGAPMKQIIRQFSIGTVAYAIMQVASAQVAITNVVPMNIPGQGTEIRVMF
CCCCCEEEECCCCHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCEEEEEE
NGLPPQPQAYQLEQPARLILDFDKAGQKLAKSLIPVTTNEASSIDVSSDDKRARVVVNLK
CCCCCCCCCEECCCCCEEEEEHHHHHHHHHHHHCCEECCCCCEECCCCCCCCEEEEEEEE
DAGAFTTRVEGNVFILKINNIQSTATPVATSAPAPQQGIGNIGFQRGAQGEGLVVIDLQG
CCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
TNTPVDVQQQGSKVVVRFPGIKIPTHLARRLNTTDFATPVASIDSYNDGSNGVISIQSTG
CCCCCCHHCCCCEEEEEECCCCCHHHHHHHCCCCHHCCCHHHCCCCCCCCCCEEEEEECC
SYEYMAYQAENKLTISLKRPQDNVRLNSKNNQNYTGKKISLDFQDIEVRRVLQLLADFTN
CEEEEEEECCCEEEEEEECCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCC
INMVTADSVQGNITLHLKDVPWDQALDIILKTKNLDKRRNGNVIWIAPVSELIKSEEDEA
CEEEEECCCCCEEEEEEECCCHHHHEEEEEEECCCCCCCCCCEEEEECHHHHHCCCCHHH
KAIAQSTKLAPLQTEYILLKYAKAADIEKLITQGRNSGTSNSNTNGSATVEPLGDSVGTL
HHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHH
LSPRGTISLDPRTNTLIINDTSQKIDQIRKMIDLLDIPVKQVMIEARIVRATTSFSKEMG
CCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEHHHHHHHHHC
VKWGILSQGINQNSNLLVGGSETTLWNLRNPDSNGTYTIERPDNLNVDLGVTTTGASSIA
CEEEHHHCCCCCCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCCEEEEEEECCCHHHH
FGLISLSDFMLDLELSALQADGYGEVISTPKVMSADKQKAKVATGVEVPYQSTTNSAAGS
HHHHHHHHHHEEEEEEEEECCCCCCCCCCCCHHCCCCHHHHEECCCCCCCCCCCCCCCCC
TATTSFKEALLSLEVTPNITPDGKILMELNIANDSINSYAQNGEAILNKNTINTNVLVNN
CCHHHHHHHHEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCCCEEEECCCCEEEEEEEC
GETVVLGGVFEQTTNNAVTKVPFLGDLPYVGRLFKKTAKSEAKNELLIFVTPRIVNDTIV
CCEEEEECCHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCC
GNH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]