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The map label for this gene is aroB

Identifier: 50086332

GI number: 50086332

Start: 3260650

End: 3261738

Strand: Reverse

Name: aroB

Synonym: ACIAD3353

Alternate gene names: 50086332

Gene position: 3261738-3260650 (Counterclockwise)

Preceding gene: 50086333

Following gene: 50086331

Centisome position: 90.64

GC content: 43.34

Gene sequence:

>1089_bases
ATGCAAACTCTACACGTTGAATTAGGCGATCGCCGTTATCCGATATTTATTGGTAGTCAGCTAAATCCTCAGAATCTACT
CGCACCTTATATCAAGGGTCGTCAGGTCATGATTGTGACCAACACCACGTTAGAACAATTATATTTGCAACATTATCAAG
ATGCATTACATGCACTTGATAAGCAGGTGGCGGTTTGTGTATTGCCTGACGGTGAAAAATATAAAAATATTGAACACCTT
AATCTGATTTTTGATGCATTGCTAAAGGCTGGCTTCAATCGGGACTGTACTGTTTTAGCTTTAGGTGGAGGTGTCATTGG
GGATATGGCTGGCTTTGCCGCTGCGAGTTTTCAGCGCGGTGTGTATTTTGTGCAGATACCTACCACTTTGTTATCTCAGG
TCGATTCAAGTGTAGGTGGTAAAACAGGTATTAACCATCCACTTGGCAAAAATATGATTGGTGCATTTAAGCAGCCTGAA
GTGGTCATGGCAGATATGTCACAGTTAAAGACTCTGCCACCACGTGAACTTTCAGCAGGCTTGGCTGAGGTCATCAAGTA
TGCGCTACTTGGGGATATTGAGTTTTTAGGCTGGCTTGAAACGCATATGGACGGCCTGATTGCAGGCGATGAAACTTTGT
TGGCCGAGGCTGTATATCGCTCTTGTGCACACAAAGCCCGAATAGTTGCCAATGATGAAAAAGAGCAGGGCGAACGTGCC
TTGCTGAATCTAGGGCATACTTTTGGTCATGCCATTGAGTCTTATCTTGGCTATGGTGAGTGGCTACATGGTGAGGCGGT
TGCAACAGGTATGGTGATGGCAGCAGATTTATCACACCGTCTGGGCTGGATTTCATCAGGTGATCTTGAGCGTACAAAAA
AAATTATCCAGCGTGCCAATTTGCCGATATCATGTCCGCCAATTCCACTGGATGAGTTCTTGTCTTACATGTCGCATGAT
AAGAAAGTACTCAATGGACAATTAAGACTGGTATTATTGCAACAGTTAGGACAAGCAATCATTACCAAGACATTTGATGT
TGAGATGATGAAAGCAGCAATTCTAGCAAATCAAGCAAGTCATACATAA

Upstream 100 bases:

>100_bases
TATCGAAACAAATCAAGGTGCTGCCCGAGAGCTGGCTCAGCAAATTTTACGTGTGATTTTAAGTTCTGGATCACATTAAG
TTTTTACTGGTTTAAATTTT

Downstream 100 bases:

>100_bases
GGTGAAAGCATGACAGCACATCGCACAGTTTGGCAAAAGATTCAGCACTATAGCTGGCTGGTCTGTGCGCTTGCCTGTCT
GTTTCTGGCGCTGATATTTT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MQTLHVELGDRRYPIFIGSQLNPQNLLAPYIKGRQVMIVTNTTLEQLYLQHYQDALHALDKQVAVCVLPDGEKYKNIEHL
NLIFDALLKAGFNRDCTVLALGGGVIGDMAGFAAASFQRGVYFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFKQPE
VVMADMSQLKTLPPRELSAGLAEVIKYALLGDIEFLGWLETHMDGLIAGDETLLAEAVYRSCAHKARIVANDEKEQGERA
LLNLGHTFGHAIESYLGYGEWLHGEAVATGMVMAADLSHRLGWISSGDLERTKKIIQRANLPISCPPIPLDEFLSYMSHD
KKVLNGQLRLVLLQQLGQAIITKTFDVEMMKAAILANQASHT

Sequences:

>Translated_362_residues
MQTLHVELGDRRYPIFIGSQLNPQNLLAPYIKGRQVMIVTNTTLEQLYLQHYQDALHALDKQVAVCVLPDGEKYKNIEHL
NLIFDALLKAGFNRDCTVLALGGGVIGDMAGFAAASFQRGVYFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFKQPE
VVMADMSQLKTLPPRELSAGLAEVIKYALLGDIEFLGWLETHMDGLIAGDETLLAEAVYRSCAHKARIVANDEKEQGERA
LLNLGHTFGHAIESYLGYGEWLHGEAVATGMVMAADLSHRLGWISSGDLERTKKIIQRANLPISCPPIPLDEFLSYMSHD
KKVLNGQLRLVLLQQLGQAIITKTFDVEMMKAAILANQASHT
>Mature_362_residues
MQTLHVELGDRRYPIFIGSQLNPQNLLAPYIKGRQVMIVTNTTLEQLYLQHYQDALHALDKQVAVCVLPDGEKYKNIEHL
NLIFDALLKAGFNRDCTVLALGGGVIGDMAGFAAASFQRGVYFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFKQPE
VVMADMSQLKTLPPRELSAGLAEVIKYALLGDIEFLGWLETHMDGLIAGDETLLAEAVYRSCAHKARIVANDEKEQGERA
LLNLGHTFGHAIESYLGYGEWLHGEAVATGMVMAADLSHRLGWISSGDLERTKKIIQRANLPISCPPIPLDEFLSYMSHD
KKVLNGQLRLVLLQQLGQAIITKTFDVEMMKAAILANQASHT

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=363, Percent_Identity=52.6170798898072, Blast_Score=350, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6320332, Length=311, Percent_Identity=38.9067524115756, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_ACIAD (Q6F7E5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047842.1
- ProteinModelPortal:   Q6F7E5
- SMR:   Q6F7E5
- STRING:   Q6F7E5
- GeneID:   2878787
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3353
- NMPDR:   fig|62977.3.peg.3035
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   Q6F7E5
- ProtClustDB:   PRK00002
- BioCyc:   ASP62977:ACIAD3353-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39744; Mature: 39744

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLHVELGDRRYPIFIGSQLNPQNLLAPYIKGRQVMIVTNTTLEQLYLQHYQDALHALD
CCEEEEEECCCCCCEEECCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHC
KQVAVCVLPDGEKYKNIEHLNLIFDALLKAGFNRDCTVLALGGGVIGDMAGFAAASFQRG
CCEEEEECCCCHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
VYFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFKQPEVVMADMSQLKTLPPRELSAG
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCHHHHHH
LAEVIKYALLGDIEFLGWLETHMDGLIAGDETLLAEAVYRSCAHKARIVANDEKEQGERA
HHHHHHHHHHCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHCEEEECCCHHHHHHH
LLNLGHTFGHAIESYLGYGEWLHGEAVATGMVMAADLSHRLGWISSGDLERTKKIIQRAN
HHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
LPISCPPIPLDEFLSYMSHDKKVLNGQLRLVLLQQLGQAIITKTFDVEMMKAAILANQAS
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HT
CC
>Mature Secondary Structure
MQTLHVELGDRRYPIFIGSQLNPQNLLAPYIKGRQVMIVTNTTLEQLYLQHYQDALHALD
CCEEEEEECCCCCCEEECCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHC
KQVAVCVLPDGEKYKNIEHLNLIFDALLKAGFNRDCTVLALGGGVIGDMAGFAAASFQRG
CCEEEEECCCCHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
VYFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFKQPEVVMADMSQLKTLPPRELSAG
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCHHHHHH
LAEVIKYALLGDIEFLGWLETHMDGLIAGDETLLAEAVYRSCAHKARIVANDEKEQGERA
HHHHHHHHHHCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHCEEEECCCHHHHHHH
LLNLGHTFGHAIESYLGYGEWLHGEAVATGMVMAADLSHRLGWISSGDLERTKKIIQRAN
HHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
LPISCPPIPLDEFLSYMSHDKKVLNGQLRLVLLQQLGQAIITKTFDVEMMKAAILANQAS
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HT
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA