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The map label for this gene is lifO

Identifier: 50086293

GI number: 50086293

Start: 3214851

End: 3215882

Strand: Direct

Name: lifO

Synonym: ACIAD3308

Alternate gene names: 50086293

Gene position: 3214851-3215882 (Clockwise)

Preceding gene: 50086289

Following gene: 50086294

Centisome position: 89.34

GC content: 39.24

Gene sequence:

>1032_bases
ATGAATGGATCGAAAAAAATTTACCTAGGGATTGGGTTAGTCGCATTATTAATGATATTCATCTATTGGTTAATGCCAAA
AGATACTGCCAATGCATCCTCTCAAATTGAGAGTACGAATGCCTCAGCAATTATAGCAACCAGTCCAGGGCAGCAGAATC
AACTTTCTGAAAATACGACACCATTTGGTAGTGTAAGTCAGCATGATACTCAAGTGAATTGCCAACTTCAGCTCAATGCA
GCTAACCACTTAATCGTCAATGAACAAACACGTAACTGCTTTGAATATTTTCTTACGCAATACGGCGAGAAAAGCCTGAC
TCAAATTGATCAAGACATCAAAAATTACTTCACTCAAAGTCTTCCCCAGCCTGCACGCGATCAGGCACAAGATTTATGGC
AACGTTATCTCAAATATCGCGAAGAACTCGGAAATTTAAAAGAACCAGCGATCGCCAAAACTGATATTGCTTATTATCGT
GCAGTATTTACCTCTAGACAGATGCTCAGACAACGTTTTTTTTCTGCGACAGAAATTGCAGGGCTGTTCGGCTCAGAAGA
TATTTATAACCAATATACCCTGGAACGGATGGCGATTCTAAATAATAGCAAACTCAGTGAGATTGAAAAAGCCAAGCAAC
TCAAAGCATTATTTGATCAATTGCCCCAAGACTGGAAAGCGAATCTTGAACAACTTTCAAAATTGGATGATTTAAAGCAA
TTAACCACATCAATCAAAAAGAATGGAGGCTCAGCACAAGAGTTACATGATATGCGAACCAATTTGGTTGGACATGATGC
CACTGCACGTCTAGAACAATTGGATGTCGAACGCTCAAACTGGAAAAGTAACGTCACTCAGTATCTTGATGAGCGTCAGA
CTATTTTAAACAGCAATATGAGTGATACAGCGAAACAGAACGCCATCAGTGCACTTAGAAGTAAAAATTTTACTGCACCA
CAGGATCAGATTCGGGTACAAGCATTTGAATCTGCAAAAGATCAAGGACAAAGCTTACCCTTTTCTGAATAA

Upstream 100 bases:

>100_bases
ATTCATCCGTTTTTGTATTATTTGTCCAAAGTTATGCTATTTTTATAATCATTCAATTCAATGATGAAATAAAAATTGCG
TCGTATTGGAATATAAAAAC

Downstream 100 bases:

>100_bases
TTTTATATCACTATTTAATCAAGGAGAAAATAGACCTTAATTTAGCTTTACCCGTGTTTTAACGGAAATAATATGCGGTT
TGAAAATGGATGAATTTTCA

Product: lipase chaperone

Products: NA

Alternate protein names: Lipase activator protein; Lipase foldase; Lipase helper protein; Lipase modulator

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNGSKKIYLGIGLVALLMIFIYWLMPKDTANASSQIESTNASAIIATSPGQQNQLSENTTPFGSVSQHDTQVNCQLQLNA
ANHLIVNEQTRNCFEYFLTQYGEKSLTQIDQDIKNYFTQSLPQPARDQAQDLWQRYLKYREELGNLKEPAIAKTDIAYYR
AVFTSRQMLRQRFFSATEIAGLFGSEDIYNQYTLERMAILNNSKLSEIEKAKQLKALFDQLPQDWKANLEQLSKLDDLKQ
LTTSIKKNGGSAQELHDMRTNLVGHDATARLEQLDVERSNWKSNVTQYLDERQTILNSNMSDTAKQNAISALRSKNFTAP
QDQIRVQAFESAKDQGQSLPFSE

Sequences:

>Translated_343_residues
MNGSKKIYLGIGLVALLMIFIYWLMPKDTANASSQIESTNASAIIATSPGQQNQLSENTTPFGSVSQHDTQVNCQLQLNA
ANHLIVNEQTRNCFEYFLTQYGEKSLTQIDQDIKNYFTQSLPQPARDQAQDLWQRYLKYREELGNLKEPAIAKTDIAYYR
AVFTSRQMLRQRFFSATEIAGLFGSEDIYNQYTLERMAILNNSKLSEIEKAKQLKALFDQLPQDWKANLEQLSKLDDLKQ
LTTSIKKNGGSAQELHDMRTNLVGHDATARLEQLDVERSNWKSNVTQYLDERQTILNSNMSDTAKQNAISALRSKNFTAP
QDQIRVQAFESAKDQGQSLPFSE
>Mature_343_residues
MNGSKKIYLGIGLVALLMIFIYWLMPKDTANASSQIESTNASAIIATSPGQQNQLSENTTPFGSVSQHDTQVNCQLQLNA
ANHLIVNEQTRNCFEYFLTQYGEKSLTQIDQDIKNYFTQSLPQPARDQAQDLWQRYLKYREELGNLKEPAIAKTDIAYYR
AVFTSRQMLRQRFFSATEIAGLFGSEDIYNQYTLERMAILNNSKLSEIEKAKQLKALFDQLPQDWKANLEQLSKLDDLKQ
LTTSIKKNGGSAQELHDMRTNLVGHDATARLEQLDVERSNWKSNVTQYLDERQTILNSNMSDTAKQNAISALRSKNFTAP
QDQIRVQAFESAKDQGQSLPFSE

Specific function: May be involved in the folding of the extracellular lipase during its passage through the periplasm

COG id: COG5380

COG function: function code O; Lipase chaperone

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase chaperone family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LIFO_ACIAD (Q43961)

Other databases:

- EMBL:   X80800
- EMBL:   CR543861
- PIR:   A57253
- RefSeq:   YP_047803.1
- ProteinModelPortal:   Q43961
- SMR:   Q43961
- STRING:   Q43961
- GeneID:   2881105
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3308
- NMPDR:   fig|62977.3.peg.2996
- eggNOG:   COG5380
- HOGENOM:   HBG688050
- OMA:   LITRDIR
- ProtClustDB:   PRK01294
- BioCyc:   ASP62977:ACIAD3308-MONOMER
- HAMAP:   MF_00790
- InterPro:   IPR004961

Pfam domain/function: PF03280 Lipase_chap

EC number: NA

Molecular weight: Translated: 39016; Mature: 39016

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd153530)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSKKIYLGIGLVALLMIFIYWLMPKDTANASSQIESTNASAIIATSPGQQNQLSENTT
CCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCC
PFGSVSQHDTQVNCQLQLNAANHLIVNEQTRNCFEYFLTQYGEKSLTQIDQDIKNYFTQS
CCCCCCCCCCEEEEEEEECCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LPQPARDQAQDLWQRYLKYREELGNLKEPAIAKTDIAYYRAVFTSRQMLRQRFFSATEIA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFGSEDIYNQYTLERMAILNNSKLSEIEKAKQLKALFDQLPQDWKANLEQLSKLDDLKQ
HHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LTTSIKKNGGSAQELHDMRTNLVGHDATARLEQLDVERSNWKSNVTQYLDERQTILNSNM
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
SDTAKQNAISALRSKNFTAPQDQIRVQAFESAKDQGQSLPFSE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure
MNGSKKIYLGIGLVALLMIFIYWLMPKDTANASSQIESTNASAIIATSPGQQNQLSENTT
CCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCC
PFGSVSQHDTQVNCQLQLNAANHLIVNEQTRNCFEYFLTQYGEKSLTQIDQDIKNYFTQS
CCCCCCCCCCEEEEEEEECCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LPQPARDQAQDLWQRYLKYREELGNLKEPAIAKTDIAYYRAVFTSRQMLRQRFFSATEIA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFGSEDIYNQYTLERMAILNNSKLSEIEKAKQLKALFDQLPQDWKANLEQLSKLDDLKQ
HHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LTTSIKKNGGSAQELHDMRTNLVGHDATARLEQLDVERSNWKSNVTQYLDERQTILNSNM
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
SDTAKQNAISALRSKNFTAPQDQIRVQAFESAKDQGQSLPFSE
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7768830