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The map label for this gene is resE [H]

Identifier: 50086176

GI number: 50086176

Start: 3103183

End: 3104442

Strand: Reverse

Name: resE [H]

Synonym: ACIAD3176

Alternate gene names: 50086176

Gene position: 3104442-3103183 (Counterclockwise)

Preceding gene: 50086181

Following gene: 50086175

Centisome position: 86.27

GC content: 37.14

Gene sequence:

>1260_bases
ATGATAGAAGCAGAACTCCCTGAAAATGAATTGGGACGGATACATGCCTTAAGTGAGTATCATATTTTGGATACCATGGC
GGAGCAATGTTTGGATGATTTAGTAGAACTTGCATCAAAAATTTGTGATGCTCCAGTTTCGATTATCAGTCTTATTGATG
AAACCCGAAGCTGGTTTAAGTCTTCACATGGTGTGCCACGAGGCGAGGTAGATCGTAAATATAGTATTTGCAGTCATGCC
ATTTTACAAAAAGAGATTTTTGTTGTTGAAGATACGCTACTAGATGAACGATTTCATGATAATCCGATTGTTCAAGGGGA
GCTAGCTGTTCGCTTTTATGCGGGGGCGCCTTTAACGACAAGTGATGGATTTAATCTTGGAACGTTATGTTTGGTAGATT
CAAAACCACGTACATTAAGTGAAGATCAATATAAGGCATTGTCCGTGCTAGCTGTGCAAGTGGTTCAGCAGTTTGAACTG
CGTAAATCCAATCTGGAAATTCAAAAGAAAAATCAAGAACTACAGTATTTGAATGAAAGTAAAGATAAGTTCTTTTCAAT
TATTGCTCATGATTTACGTGCCCCATTTCACGGTATTTTAGGATTTTCTGATGTTTTAGAAACAGAAATTGAAACATTAG
ACGAGCAAGGTATTCGGGATATTGCAGGTTATTTGCGTAGTACCGCACAGGCGACATTTAAGCTTCTGGAAAATCTTTTA
CAATGGGCAATGTCAGAAGGAGGAGCGATTGTTTACAATCCTCAATCGATTAATATGCCTGAATTGATGACAGATGTTTG
TGAAATTCTTCAGGCGGTTGCACAGAAAAAAAACATTCAAATTGAATGTGATATCGAGACTGATTTACACTGTTTTGTCG
ATTTTAACATGATGTTGTCTGTTCTTCAGAATCTAATTTCCAATGCACTTAAATTTACGCCGCACGGTGGAAAAATCTAT
TTAACTGCACATACGGCTCAAGATCATGTCGAAATTAGTGTTCGTGATACCGGTGTGGGAATGTCAGACGAATCTTTCAA
CAACTTTAATTTACGTAAGCAGATTCGTAGTGAAAAAGGAACTGATGGTGAGAAGGGATCAGGTTTGGGATTGCTATTGT
GTTTACAGTTTATCGAAAAGAATCATGGGAGTTTGAGTGTTAAAACTGAAAAAGATGTAGGCAGTACTTTTGTTATTCAA
CTTCCGATCAATGTTGATTATAAAGCTGCATTAAATGCAGATTTTAAAAATATTGCGTGA

Upstream 100 bases:

>100_bases
AATAATGTTGAAGTCGTCTTAAATACTTTAGCAAAAATAAAAGACATAAATAACATGGTTCATACGAACTTGACTCGGCT
CAACCCTAATCGGACTAATC

Downstream 100 bases:

>100_bases
ATGATAGCATCATGATTTCGATGTTTAGTACATAGGATGCTGTTCTATCAGTAGGTATGTATTCAAAGCATGAAAGTGAA
TTCACCTGTTTAGCTGTTAA

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MIEAELPENELGRIHALSEYHILDTMAEQCLDDLVELASKICDAPVSIISLIDETRSWFKSSHGVPRGEVDRKYSICSHA
ILQKEIFVVEDTLLDERFHDNPIVQGELAVRFYAGAPLTTSDGFNLGTLCLVDSKPRTLSEDQYKALSVLAVQVVQQFEL
RKSNLEIQKKNQELQYLNESKDKFFSIIAHDLRAPFHGILGFSDVLETEIETLDEQGIRDIAGYLRSTAQATFKLLENLL
QWAMSEGGAIVYNPQSINMPELMTDVCEILQAVAQKKNIQIECDIETDLHCFVDFNMMLSVLQNLISNALKFTPHGGKIY
LTAHTAQDHVEISVRDTGVGMSDESFNNFNLRKQIRSEKGTDGEKGSGLGLLLCLQFIEKNHGSLSVKTEKDVGSTFVIQ
LPINVDYKAALNADFKNIA

Sequences:

>Translated_419_residues
MIEAELPENELGRIHALSEYHILDTMAEQCLDDLVELASKICDAPVSIISLIDETRSWFKSSHGVPRGEVDRKYSICSHA
ILQKEIFVVEDTLLDERFHDNPIVQGELAVRFYAGAPLTTSDGFNLGTLCLVDSKPRTLSEDQYKALSVLAVQVVQQFEL
RKSNLEIQKKNQELQYLNESKDKFFSIIAHDLRAPFHGILGFSDVLETEIETLDEQGIRDIAGYLRSTAQATFKLLENLL
QWAMSEGGAIVYNPQSINMPELMTDVCEILQAVAQKKNIQIECDIETDLHCFVDFNMMLSVLQNLISNALKFTPHGGKIY
LTAHTAQDHVEISVRDTGVGMSDESFNNFNLRKQIRSEKGTDGEKGSGLGLLLCLQFIEKNHGSLSVKTEKDVGSTFVIQ
LPINVDYKAALNADFKNIA
>Mature_419_residues
MIEAELPENELGRIHALSEYHILDTMAEQCLDDLVELASKICDAPVSIISLIDETRSWFKSSHGVPRGEVDRKYSICSHA
ILQKEIFVVEDTLLDERFHDNPIVQGELAVRFYAGAPLTTSDGFNLGTLCLVDSKPRTLSEDQYKALSVLAVQVVQQFEL
RKSNLEIQKKNQELQYLNESKDKFFSIIAHDLRAPFHGILGFSDVLETEIETLDEQGIRDIAGYLRSTAQATFKLLENLL
QWAMSEGGAIVYNPQSINMPELMTDVCEILQAVAQKKNIQIECDIETDLHCFVDFNMMLSVLQNLISNALKFTPHGGKIY
LTAHTAQDHVEISVRDTGVGMSDESFNNFNLRKQIRSEKGTDGEKGSGLGLLLCLQFIEKNHGSLSVKTEKDVGSTFVIQ
LPINVDYKAALNADFKNIA

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=237, Percent_Identity=29.535864978903, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI145693157, Length=290, Percent_Identity=28.2758620689655, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=24.1379310344828, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=262, Percent_Identity=25.5725190839695, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=24.1666666666667, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=23.574144486692, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=23.5042735042735, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=23.1707317073171, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=254, Percent_Identity=24.8031496062992, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=23.3480176211454, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=23.8805970149254, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=24.4813278008299, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46887; Mature: 46887

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEAELPENELGRIHALSEYHILDTMAEQCLDDLVELASKICDAPVSIISLIDETRSWFK
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SSHGVPRGEVDRKYSICSHAILQKEIFVVEDTLLDERFHDNPIVQGELAVRFYAGAPLTT
HCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCCEECEEEEEEEECCCCCC
SDGFNLGTLCLVDSKPRTLSEDQYKALSVLAVQVVQQFELRKSNLEIQKKNQELQYLNES
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHH
KDKFFSIIAHDLRAPFHGILGFSDVLETEIETLDEQGIRDIAGYLRSTAQATFKLLENLL
HHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWAMSEGGAIVYNPQSINMPELMTDVCEILQAVAQKKNIQIECDIETDLHCFVDFNMMLS
HHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHH
VLQNLISNALKFTPHGGKIYLTAHTAQDHVEISVRDTGVGMSDESFNNFNLRKQIRSEKG
HHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCC
TDGEKGSGLGLLLCLQFIEKNHGSLSVKTEKDVGSTFVIQLPINVDYKAALNADFKNIA
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCHHHCCCCHHCCC
>Mature Secondary Structure
MIEAELPENELGRIHALSEYHILDTMAEQCLDDLVELASKICDAPVSIISLIDETRSWFK
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SSHGVPRGEVDRKYSICSHAILQKEIFVVEDTLLDERFHDNPIVQGELAVRFYAGAPLTT
HCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHCCCCCCEECEEEEEEEECCCCCC
SDGFNLGTLCLVDSKPRTLSEDQYKALSVLAVQVVQQFELRKSNLEIQKKNQELQYLNES
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHH
KDKFFSIIAHDLRAPFHGILGFSDVLETEIETLDEQGIRDIAGYLRSTAQATFKLLENLL
HHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWAMSEGGAIVYNPQSINMPELMTDVCEILQAVAQKKNIQIECDIETDLHCFVDFNMMLS
HHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHHH
VLQNLISNALKFTPHGGKIYLTAHTAQDHVEISVRDTGVGMSDESFNNFNLRKQIRSEKG
HHHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCC
TDGEKGSGLGLLLCLQFIEKNHGSLSVKTEKDVGSTFVIQLPINVDYKAALNADFKNIA
CCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]