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The map label for this gene is fhuE [H]

Identifier: 50086162

GI number: 50086162

Start: 3088813

End: 3090969

Strand: Reverse

Name: fhuE [H]

Synonym: ACIAD3161

Alternate gene names: 50086162

Gene position: 3090969-3088813 (Counterclockwise)

Preceding gene: 50086167

Following gene: 50086158

Centisome position: 85.89

GC content: 40.15

Gene sequence:

>2157_bases
TTGTTCATGTTTCATTGTGTCATTGGAAATTTTAAAGTTCATCCGCTGGTCATGGCGATGACTATGCTTGCTTCTCCATT
CATTTATGCTGAACCTACTGAAAAGGGAGAGGTATTACCAACGATTGAGTTAAAAGCAGACTCCGAACAACAAGCCAATA
CTTATGCTGCCAATACAGCTTCTACTGCATTACCTCTAAAACTGAATATTAAGGAAATTCCACAGTCTGTTTCTGTCATT
ACCCAGCAGCGTATGCAAGATCAAGGCTTAACAACTTTAGTTGAAGTAGCAGAAAACGTGACTGGAGTGAACGTTAATCG
TTATGAGACGAATCGTGGTGGATTATATTCACGAGGATTTGTTATCGATAACTATATTATTGATGGGATACCAACCACGT
ATTCGTTGCCTTGGTCATCTGGTGAAATATTCTCTAGTACGGCGATTTATGATCACATTGATGTTGTACGTGGCTCGACA
GGCCTAACAACGGGCACAGGTAATCCATCCGCAGCGATTAATATGGTACGAAAACGAGCTACCAGCAAGATTCCAGCAGC
AACTATAGAAGTAAGTGGTGGAAGTTGGGACAATTATCGGGTATTGGGAGATATTTCTAATCGCCTCAATCAATCAGGTT
CCCTTCGGGGAAGAGCCGTTGCTCAATATGAGCAGGGAGATAGCTACACAGATTTACTCAGTAAGCAACGTTTAACTTTG
CTTTTAACAGGTGAGGCAGATCTCACAGATTCGACGCTTCTTTCAGCAGGTGTAAGTTATCAGGAAGACGACCCGCGAGG
TCCAATGTGGGGAGGATTGCCTGCTTATTTCAGTGATGGTAGTCGTACCACGTGGTGGAAAGGATTAACCACCTCTCAGG
ACTGGACGCGCTGGAATGTTAAATATACCAATTGGTTTGCAGACTTAACTCAAAAAATCAATGAGAACTGGAATGTTAAG
CTGGCTTATTCACATGGTAAGCGTGAAGCAGATTCCAAATTATTTTATGTATCAGGTAATCCAGATAAAACGACAGGTTT
AGGTTTATCTGGATTTGCGGGTGCGTATGATGTAAATGTTGATCAGGATGATGTGACATTACAACTTGATGGTCAATTCA
ATTTATTTGGTCAAAATCATCGAGTGGTGGCGGGTTATCAATATCTAAATCAGGATTTTATTGCATTAGGTCGCTCTGTT
CAGGATATTAGTACAAGTAGTATTTATGCTTGGAATACATCTTTGCCAGAACCTGCATGGGGTGCATGGACACCTGCTGA
AAAATATACGGTAAAGCAGAATGCAGTGTTTGCGGCAACACAATTGACCTTACTTGACCCTTTGAAACTGATTCTCGGTG
GGAGAGTGACGCAGTATGAAAAAAACCTTCCTTTAAAAAAGAAGACGATTGAATATGATCATGAATTTATCCCTTATGCA
GGGCTGATCTACGATATCAATCCAACTTATTCGGCCTATGTCAGTTATACCAGTATCTTTCAGCCACAAGATGCCAAAGA
TATTAATAATAATTATTTAGATCCAATTGAAGGCAATAGTACCGAAATTGGTGTGAAATCTTCTTGGTTTGATCAGCGCT
TAAATGGTTCTTTGGCTATTTTTCAAATCAAGCAAGATCATTTGGCACAATCTATAGGGGAGAAGATTCCTGGTACTAAC
AATGAAGATGCGTATCGCGCTGCTGAGGGCACAGAAAGTAAAGGTTTTGAACTCGAACTGAGTGGGAAGGTCACAGATCA
GTGGAATATTACTGCGGGTTATAGTCAGTACAAAGCAACCGATGCCAATGGTGCAGATGTAAACTCACAATTACCACGTA
AGCAGATACAAACTTATACGACGTACCAGCTTCCAGACAAATGGGAGGCTTTAACCATTGGTGGTGGAATCAATTGGCAA
AGTGAAACCTATATTAAGGCAAGTAATGCACCTAAAAATGCAGATTCACGGGTTGAACAAGGTGCTTATGCATTGGTTAA
TCTAATGGCTAAATATAAAATATCTAAAGATTTTTCTGCACAGCTCAATATTAATAATGTATTTAATCAAGATTATTACG
GTGTTTTTGCGACTTATGGTCAGATCACTCAGGGTGCACCACGTAATGCAACCTTAACGTTTAGATATCATTTCTAA

Upstream 100 bases:

>100_bases
TTATTGTTATTTTTTGTTGATTGATTTTATTCGTCTGTATTTTATTTTTGATTAATGCTTAGGTGTTTGTGTTAGTCGCC
AGCTAAGCGGATAAGGATTA

Downstream 100 bases:

>100_bases
AAAAGAGCCAATGATCACAGCAATTGCTCATTGGCTCTTTGTTTTATTGTTCTTGATAAGGATTCTCTAATCCTAATTTC
GCCAGAATCTCAATTTCCAG

Product: outer membrane porin

Products: NA

Alternate protein names: Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MFMFHCVIGNFKVHPLVMAMTMLASPFIYAEPTEKGEVLPTIELKADSEQQANTYAANTASTALPLKLNIKEIPQSVSVI
TQQRMQDQGLTTLVEVAENVTGVNVNRYETNRGGLYSRGFVIDNYIIDGIPTTYSLPWSSGEIFSSTAIYDHIDVVRGST
GLTTGTGNPSAAINMVRKRATSKIPAATIEVSGGSWDNYRVLGDISNRLNQSGSLRGRAVAQYEQGDSYTDLLSKQRLTL
LLTGEADLTDSTLLSAGVSYQEDDPRGPMWGGLPAYFSDGSRTTWWKGLTTSQDWTRWNVKYTNWFADLTQKINENWNVK
LAYSHGKREADSKLFYVSGNPDKTTGLGLSGFAGAYDVNVDQDDVTLQLDGQFNLFGQNHRVVAGYQYLNQDFIALGRSV
QDISTSSIYAWNTSLPEPAWGAWTPAEKYTVKQNAVFAATQLTLLDPLKLILGGRVTQYEKNLPLKKKTIEYDHEFIPYA
GLIYDINPTYSAYVSYTSIFQPQDAKDINNNYLDPIEGNSTEIGVKSSWFDQRLNGSLAIFQIKQDHLAQSIGEKIPGTN
NEDAYRAAEGTESKGFELELSGKVTDQWNITAGYSQYKATDANGADVNSQLPRKQIQTYTTYQLPDKWEALTIGGGINWQ
SETYIKASNAPKNADSRVEQGAYALVNLMAKYKISKDFSAQLNINNVFNQDYYGVFATYGQITQGAPRNATLTFRYHF

Sequences:

>Translated_718_residues
MFMFHCVIGNFKVHPLVMAMTMLASPFIYAEPTEKGEVLPTIELKADSEQQANTYAANTASTALPLKLNIKEIPQSVSVI
TQQRMQDQGLTTLVEVAENVTGVNVNRYETNRGGLYSRGFVIDNYIIDGIPTTYSLPWSSGEIFSSTAIYDHIDVVRGST
GLTTGTGNPSAAINMVRKRATSKIPAATIEVSGGSWDNYRVLGDISNRLNQSGSLRGRAVAQYEQGDSYTDLLSKQRLTL
LLTGEADLTDSTLLSAGVSYQEDDPRGPMWGGLPAYFSDGSRTTWWKGLTTSQDWTRWNVKYTNWFADLTQKINENWNVK
LAYSHGKREADSKLFYVSGNPDKTTGLGLSGFAGAYDVNVDQDDVTLQLDGQFNLFGQNHRVVAGYQYLNQDFIALGRSV
QDISTSSIYAWNTSLPEPAWGAWTPAEKYTVKQNAVFAATQLTLLDPLKLILGGRVTQYEKNLPLKKKTIEYDHEFIPYA
GLIYDINPTYSAYVSYTSIFQPQDAKDINNNYLDPIEGNSTEIGVKSSWFDQRLNGSLAIFQIKQDHLAQSIGEKIPGTN
NEDAYRAAEGTESKGFELELSGKVTDQWNITAGYSQYKATDANGADVNSQLPRKQIQTYTTYQLPDKWEALTIGGGINWQ
SETYIKASNAPKNADSRVEQGAYALVNLMAKYKISKDFSAQLNINNVFNQDYYGVFATYGQITQGAPRNATLTFRYHF
>Mature_718_residues
MFMFHCVIGNFKVHPLVMAMTMLASPFIYAEPTEKGEVLPTIELKADSEQQANTYAANTASTALPLKLNIKEIPQSVSVI
TQQRMQDQGLTTLVEVAENVTGVNVNRYETNRGGLYSRGFVIDNYIIDGIPTTYSLPWSSGEIFSSTAIYDHIDVVRGST
GLTTGTGNPSAAINMVRKRATSKIPAATIEVSGGSWDNYRVLGDISNRLNQSGSLRGRAVAQYEQGDSYTDLLSKQRLTL
LLTGEADLTDSTLLSAGVSYQEDDPRGPMWGGLPAYFSDGSRTTWWKGLTTSQDWTRWNVKYTNWFADLTQKINENWNVK
LAYSHGKREADSKLFYVSGNPDKTTGLGLSGFAGAYDVNVDQDDVTLQLDGQFNLFGQNHRVVAGYQYLNQDFIALGRSV
QDISTSSIYAWNTSLPEPAWGAWTPAEKYTVKQNAVFAATQLTLLDPLKLILGGRVTQYEKNLPLKKKTIEYDHEFIPYA
GLIYDINPTYSAYVSYTSIFQPQDAKDINNNYLDPIEGNSTEIGVKSSWFDQRLNGSLAIFQIKQDHLAQSIGEKIPGTN
NEDAYRAAEGTESKGFELELSGKVTDQWNITAGYSQYKATDANGADVNSQLPRKQIQTYTTYQLPDKWEALTIGGGINWQ
SETYIKASNAPKNADSRVEQGAYALVNLMAKYKISKDFSAQLNINNVFNQDYYGVFATYGQITQGAPRNATLTFRYHF

Specific function: Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid [H]

COG id: COG4773

COG function: function code P; Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=717, Percent_Identity=39.0516039051604, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1786344, Length=732, Percent_Identity=22.4043715846995, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787024, Length=255, Percent_Identity=24.3137254901961, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79738; Mature: 79738

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMFHCVIGNFKVHPLVMAMTMLASPFIYAEPTEKGEVLPTIELKADSEQQANTYAANTA
CEEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCHHCCEEECCCC
STALPLKLNIKEIPQSVSVITQQRMQDQGLTTLVEVAENVTGVNVNRYETNRGGLYSRGF
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEECCE
VIDNYIIDGIPTTYSLPWSSGEIFSSTAIYDHIDVVRGSTGLTTGTGNPSAAINMVRKRA
EEECEEECCCCCEEECCCCCCCEEECCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHH
TSKIPAATIEVSGGSWDNYRVLGDISNRLNQSGSLRGRAVAQYEQGDSYTDLLSKQRLTL
CCCCCEEEEEECCCCCCCEEEEECHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCEEE
LLTGEADLTDSTLLSAGVSYQEDDPRGPMWGGLPAYFSDGSRTTWWKGLTTSQDWTRWNV
EEECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECCCCCCCCCEEEEE
KYTNWFADLTQKINENWNVKLAYSHGKREADSKLFYVSGNPDKTTGLGLSGFAGAYDVNV
EEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCC
DQDDVTLQLDGQFNLFGQNHRVVAGYQYLNQDFIALGRSVQDISTSSIYAWNTSLPEPAW
CCCCEEEEECCEEEEECCCCEEEEEHHHHCHHHHHHCCCHHCCCCCEEEEECCCCCCCCC
GAWTPAEKYTVKQNAVFAATQLTLLDPLKLILGGRVTQYEKNLPLKKKTIEYDHEFIPYA
CCCCCCCCEEEECCEEEEEEEEHHHHHHHHHHCCCEEEHHCCCCCCEEEECCCCCCCCCC
GLIYDINPTYSAYVSYTSIFQPQDAKDINNNYLDPIEGNSTEIGVKSSWFDQRLNGSLAI
CEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCCEEE
FQIKQDHLAQSIGEKIPGTNNEDAYRAAEGTESKGFELELSGKVTDQWNITAGYSQYKAT
EEECHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCEECCCEEEEECCCCEEEC
DANGADVNSQLPRKQIQTYTTYQLPDKWEALTIGGGINWQSETYIKASNAPKNADSRVEQ
CCCCCCCCCCCCHHHHCEEEEEECCCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHH
GAYALVNLMAKYKISKDFSAQLNINNVFNQDYYGVFATYGQITQGAPRNATLTFRYHF
HHHHHHHHHHHHEECCCCEEEEEECHHCCCCCCEEEEECCHHHCCCCCCCEEEEEEEC
>Mature Secondary Structure
MFMFHCVIGNFKVHPLVMAMTMLASPFIYAEPTEKGEVLPTIELKADSEQQANTYAANTA
CEEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCHHCCEEECCCC
STALPLKLNIKEIPQSVSVITQQRMQDQGLTTLVEVAENVTGVNVNRYETNRGGLYSRGF
CCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCEECCE
VIDNYIIDGIPTTYSLPWSSGEIFSSTAIYDHIDVVRGSTGLTTGTGNPSAAINMVRKRA
EEECEEECCCCCEEECCCCCCCEEECCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHH
TSKIPAATIEVSGGSWDNYRVLGDISNRLNQSGSLRGRAVAQYEQGDSYTDLLSKQRLTL
CCCCCEEEEEECCCCCCCEEEEECHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCEEE
LLTGEADLTDSTLLSAGVSYQEDDPRGPMWGGLPAYFSDGSRTTWWKGLTTSQDWTRWNV
EEECCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECCCCCCCCCEEEEE
KYTNWFADLTQKINENWNVKLAYSHGKREADSKLFYVSGNPDKTTGLGLSGFAGAYDVNV
EEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCC
DQDDVTLQLDGQFNLFGQNHRVVAGYQYLNQDFIALGRSVQDISTSSIYAWNTSLPEPAW
CCCCEEEEECCEEEEECCCCEEEEEHHHHCHHHHHHCCCHHCCCCCEEEEECCCCCCCCC
GAWTPAEKYTVKQNAVFAATQLTLLDPLKLILGGRVTQYEKNLPLKKKTIEYDHEFIPYA
CCCCCCCCEEEECCEEEEEEEEHHHHHHHHHHCCCEEEHHCCCCCCEEEECCCCCCCCCC
GLIYDINPTYSAYVSYTSIFQPQDAKDINNNYLDPIEGNSTEIGVKSSWFDQRLNGSLAI
CEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCCEEE
FQIKQDHLAQSIGEKIPGTNNEDAYRAAEGTESKGFELELSGKVTDQWNITAGYSQYKAT
EEECHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCEECCCEEEEECCCCEEEC
DANGADVNSQLPRKQIQTYTTYQLPDKWEALTIGGGINWQSETYIKASNAPKNADSRVEQ
CCCCCCCCCCCCHHHHCEEEEEECCCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHH
GAYALVNLMAKYKISKDFSAQLNINNVFNQDYYGVFATYGQITQGAPRNATLTFRYHF
HHHHHHHHHHHHEECCCCEEEEEECHHCCCCCCEEEEECCHHHCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162465; 8905232; 9278503; 3032906 [H]