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The map label for this gene is yajO [H]

Identifier: 50086131

GI number: 50086131

Start: 3054846

End: 3055904

Strand: Reverse

Name: yajO [H]

Synonym: ACIAD3128

Alternate gene names: 50086131

Gene position: 3055904-3054846 (Counterclockwise)

Preceding gene: 50086134

Following gene: 50086128

Centisome position: 84.92

GC content: 43.44

Gene sequence:

>1059_bases
TTGAGAGCCATCATGAAATATCGCTTTTTAGGCAACTCTGGTTTGCAGGTTTCAGAATTAGGTTTTGGTGCGGGAACGCT
AGGAGGCAAAGGACAGATCTTTTCTGCGTGGGGACAACCCGACCAGAATGAGGCCAATCGACTGATTAAGATCTGTTTGG
ATGCAGGCATTAATTATTTTGATACAGCAGATGTTTATTCTGACGGAGCGTCAGAAACAATGTTAGGCCGAGGCTTAGGT
TCAGAAAGAAAAAACAATATTATTTCGACCAAGATTGGATTACGTTACGCATCTGGTTTAAATGAGACTGGCTTTCATCG
TCATTACCTAAAAAAAGCAGTCGAAGCCTCTCTTAAGCGATTAAATACCGATTACATTGATGTTTTGCAATTGCATCAAT
TTGATAGTTTTACCTCGCTTGAGCAGCTGATGCGCACCTTAAATGAGTTAGTACAAAGTGGAAAAGTTCGCTTTATTGGG
GTATCGAACTTTTCGGGCTGGCAACTGATGAAGGCACAAGCGATTGCGGAGCAGTATGGCTATGAAAAATTTGTGGCAAA
TCAAGTTTATTATTCTTTGATTGGTCGAGATTATGAATGGGAACTTATGCCATTAAATGACGATCAACACATCGGAGCTG
TGATTTGGAGTCCATTGGGCTGGGGACGTCTGACAGGCCGCTTTGATCGTGAGCATCCAATACCCGCATCAAGCCGTTTG
CATCAAACAGCGCAATATGCACCTCCAGTTGATGACGAACATTTATATCGGGTACTTGAGGTGATGCAACAGATTAACAC
TGAAACAGGTTATTCGATTCCGCAAATTGCACTTTCCTGGTTGTTAGGGCGTCCCACCGTTTCAAGTGTTTTGGTGGGTG
CCAGAAATGAGCAGCAACTCCGTGACAATTTGCTCGCTCAGAACTGCGATCTGAGTACAGAATATATTGAAAAACTCAAT
CAGATTAGCGCTGTGTCTCCGCCGTATCCTTATTATCCATACTGGAATGGGCAGTTTGGAGAGCGCTTCAAGCCCATTGT
TGCATCTCAGATGGGATAG

Upstream 100 bases:

>100_bases
GTATTCATAATCAATAAAATCAGAATAGTCTTTTCTGATTATCCTGCTTTTTTAAAAAATCTTATAGACCTATCTTGGAT
GATGTAATGAATCGTTCATA

Downstream 100 bases:

>100_bases
TTGTCGAAACTATCGATGGTTTACAAGAGATTATTATCTTGTGCCTGAATGGGTGGAGGTGTTGGTTTACCTAAGGTACT
GAGTAATTCAATCTCAATCA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRAIMKYRFLGNSGLQVSELGFGAGTLGGKGQIFSAWGQPDQNEANRLIKICLDAGINYFDTADVYSDGASETMLGRGLG
SERKNNIISTKIGLRYASGLNETGFHRHYLKKAVEASLKRLNTDYIDVLQLHQFDSFTSLEQLMRTLNELVQSGKVRFIG
VSNFSGWQLMKAQAIAEQYGYEKFVANQVYYSLIGRDYEWELMPLNDDQHIGAVIWSPLGWGRLTGRFDREHPIPASSRL
HQTAQYAPPVDDEHLYRVLEVMQQINTETGYSIPQIALSWLLGRPTVSSVLVGARNEQQLRDNLLAQNCDLSTEYIEKLN
QISAVSPPYPYYPYWNGQFGERFKPIVASQMG

Sequences:

>Translated_352_residues
MRAIMKYRFLGNSGLQVSELGFGAGTLGGKGQIFSAWGQPDQNEANRLIKICLDAGINYFDTADVYSDGASETMLGRGLG
SERKNNIISTKIGLRYASGLNETGFHRHYLKKAVEASLKRLNTDYIDVLQLHQFDSFTSLEQLMRTLNELVQSGKVRFIG
VSNFSGWQLMKAQAIAEQYGYEKFVANQVYYSLIGRDYEWELMPLNDDQHIGAVIWSPLGWGRLTGRFDREHPIPASSRL
HQTAQYAPPVDDEHLYRVLEVMQQINTETGYSIPQIALSWLLGRPTVSSVLVGARNEQQLRDNLLAQNCDLSTEYIEKLN
QISAVSPPYPYYPYWNGQFGERFKPIVASQMG
>Mature_352_residues
MRAIMKYRFLGNSGLQVSELGFGAGTLGGKGQIFSAWGQPDQNEANRLIKICLDAGINYFDTADVYSDGASETMLGRGLG
SERKNNIISTKIGLRYASGLNETGFHRHYLKKAVEASLKRLNTDYIDVLQLHQFDSFTSLEQLMRTLNELVQSGKVRFIG
VSNFSGWQLMKAQAIAEQYGYEKFVANQVYYSLIGRDYEWELMPLNDDQHIGAVIWSPLGWGRLTGRFDREHPIPASSRL
HQTAQYAPPVDDEHLYRVLEVMQQINTETGYSIPQIALSWLLGRPTVSSVLVGARNEQQLRDNLLAQNCDLSTEYIEKLN
QISAVSPPYPYYPYWNGQFGERFKPIVASQMG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=334, Percent_Identity=32.3353293413174, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4504825, Length=337, Percent_Identity=32.0474777448071, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436964, Length=339, Percent_Identity=33.0383480825959, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI27436962, Length=313, Percent_Identity=33.5463258785943, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI27436966, Length=339, Percent_Identity=32.4483775811209, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI27436971, Length=312, Percent_Identity=29.8076923076923, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI223718702, Length=296, Percent_Identity=25.6756756756757, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI41152114, Length=299, Percent_Identity=25.752508361204, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI41327764, Length=284, Percent_Identity=25.3521126760563, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI223718708, Length=141, Percent_Identity=29.0780141843972, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=33.6336336336336, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=30, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1788070, Length=333, Percent_Identity=31.5315315315315, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789199, Length=362, Percent_Identity=28.1767955801105, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788081, Length=177, Percent_Identity=32.2033898305085, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787674, Length=315, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994888, Length=311, Percent_Identity=26.3665594855305, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786400, Length=290, Percent_Identity=25.5172413793103, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=320, Percent_Identity=28.125, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=29.5774647887324, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=28.3987915407855, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=305, Percent_Identity=28.8524590163934, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=27.2189349112426, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=27.906976744186, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321052, Length=164, Percent_Identity=31.7073170731707, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646155, Length=342, Percent_Identity=28.9473684210526, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24640980, Length=349, Percent_Identity=25.214899713467, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI45549126, Length=321, Percent_Identity=25.2336448598131, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646159, Length=309, Percent_Identity=29.4498381877023, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39741; Mature: 39741

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00060 ADH_IRON_2 ; PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIMKYRFLGNSGLQVSELGFGAGTLGGKGQIFSAWGQPDQNEANRLIKICLDAGINYF
CCCHHEEEEECCCCCEEHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCC
DTADVYSDGASETMLGRGLGSERKNNIISTKIGLRYASGLNETGFHRHYLKKAVEASLKR
CCHHHHCCCCCHHHHHCCCCCHHHCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LNTDYIDVLQLHQFDSFTSLEQLMRTLNELVQSGKVRFIGVSNFSGWQLMKAQAIAEQYG
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHC
YEKFVANQVYYSLIGRDYEWELMPLNDDQHIGAVIWSPLGWGRLTGRFDREHPIPASSRL
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCHHCCCCCCCCCCCHHHHH
HQTAQYAPPVDDEHLYRVLEVMQQINTETGYSIPQIALSWLLGRPTVSSVLVGARNEQQL
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHH
RDNLLAQNCDLSTEYIEKLNQISAVSPPYPYYPYWNGQFGERFKPIVASQMG
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAIMKYRFLGNSGLQVSELGFGAGTLGGKGQIFSAWGQPDQNEANRLIKICLDAGINYF
CCCHHEEEEECCCCCEEHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCC
DTADVYSDGASETMLGRGLGSERKNNIISTKIGLRYASGLNETGFHRHYLKKAVEASLKR
CCHHHHCCCCCHHHHHCCCCCHHHCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
LNTDYIDVLQLHQFDSFTSLEQLMRTLNELVQSGKVRFIGVSNFSGWQLMKAQAIAEQYG
HCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHC
YEKFVANQVYYSLIGRDYEWELMPLNDDQHIGAVIWSPLGWGRLTGRFDREHPIPASSRL
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCHHCCCCCCCCCCCHHHHH
HQTAQYAPPVDDEHLYRVLEVMQQINTETGYSIPQIALSWLLGRPTVSSVLVGARNEQQL
HHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCHHHH
RDNLLAQNCDLSTEYIEKLNQISAVSPPYPYYPYWNGQFGERFKPIVASQMG
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]